Ivan Yuhanna

Ivan Yuhanna

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Ivan Yuhanna

Ivan Yuhanna

Publications by authors named "Ivan Yuhanna"

30Publications

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1PubMed Central Citations

SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis.

Nature 2019 05 24;569(7757):565-569. Epub 2019 Apr 24.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1038/s41586-019-1140-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631346PMC
May 2019

Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice.

Diabetes 2016 07 26;65(7):1996-2005. Epub 2016 Apr 26.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX

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http://dx.doi.org/10.2337/db15-1605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915578PMC
July 2016

Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial cell adhesion and lesion macrophage accumulation.

Sci Signal 2016 Mar 15;9(419):ra29. Epub 2016 Mar 15.

Department of Molecular Genetics, University of Texas (UT) Southwestern Medical Center, Dallas, TX 75390, USA. Center for Translational Neurodegeneration Research, UT Southwestern Medical Center, Dallas, TX 75390, USA. Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX 75390, USA. Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, Dallas, TX 75390, USA. Center for Neuroscience, Department of Neuroanatomy, Albert-Ludwigs-University, 79104 Freiburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053773PMC
http://dx.doi.org/10.1126/scisignal.aad5578DOI Listing
March 2016

IgG receptor FcγRIIB plays a key role in obesity-induced hypertension.

Hypertension 2015 Feb 3;65(2):456-62. Epub 2014 Nov 3.

From the Department of Pediatrics, Section of Neonatology, Baylor College of Medicine, Houston, TX (N.C.S., B.-M.D.B.); and Department of Internal Medicine, Division of Cardiology, Hypertension Section (W.V.) and Department of Pediatrics, Center for Pulmonary and Vascular Biology (K.T., I.S.Y., K.L.C., C.M., P.W.S.), University of Texas Southwestern Medical Center, Dallas.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419357PMC
February 2015

HDL cholesterol efflux capacity and incident cardiovascular events.

N Engl J Med 2014 Dec 18;371(25):2383-93. Epub 2014 Nov 18.

From the Division of Cardiology, Department of Internal Medicine (A.R., A.K., J.D.B., E.G.G., C.R.A., I.J.N., J.A.L.), and the Center for Pulmonary and Vascular Biology, Department of Pediatrics (I.S.Y., P.W.S.), University of Texas Southwestern Medical Center, Dallas; the Department of Internal Medicine, Emory University, Atlanta (K.E.W.); and the Departments of Genetics and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (D.R.R.).

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http://dx.doi.org/10.1056/NEJMoa1409065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308988PMC
December 2014

Genetic variants of ApoE and ApoER2 differentially modulate endothelial function.

Proc Natl Acad Sci U S A 2014 Sep 2;111(37):13493-8. Epub 2014 Sep 2.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, and

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http://dx.doi.org/10.1073/pnas.1402106111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169937PMC
September 2014

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.

Cell Rep 2013 Nov 7;5(3):637-45. Epub 2013 Nov 7.

Department of Pediatrics, Division of Pulmonary and Vascular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950897PMC
November 2013

LXRβ/estrogen receptor-α signaling in lipid rafts preserves endothelial integrity.

J Clin Invest 2013 Aug 8;123(8):3488-97. Epub 2013 Jul 8.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1172/JCI66533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726156PMC
August 2013

Point mutations in the ERα Gαi binding domain segregate nonnuclear from nuclear receptor function.

Mol Endocrinol 2013 Jan 14;27(1):2-11. Epub 2012 Dec 14.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1210/me.2011-1378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545213PMC
January 2013

Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function.

Circ Res 2011 Oct 22;109(10):1132-40. Epub 2011 Sep 22.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.254573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215097PMC
October 2011

The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity.

Circ Res 2008 Feb 3;102(4):480-7. Epub 2008 Jan 3.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, USA.

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http://circres.ahajournals.org/content/102/4/480.full.pdf
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http://circres.ahajournals.org/cgi/doi/10.1161/CIRCRESAHA.10
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http://dx.doi.org/10.1161/CIRCRESAHA.107.159079DOI Listing
February 2008

27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen.

Nat Med 2007 Oct 16;13(10):1185-92. Epub 2007 Sep 16.

Department of Pharmacology and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, Texas 75390-9050, USA.

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http://dx.doi.org/10.1038/nm1641DOI Listing
October 2007

Nitric oxide attenuates epithelial-mesenchymal transition in alveolar epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2007 Jul 11;293(1):L212-21. Epub 2007 May 11.

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1152/ajplung.00475.2006DOI Listing
July 2007

Direct interactions with G α i and G βγ mediate nongenomic signaling by estrogen receptor α .

Mol Endocrinol 2007 Jun 3;21(6):1370-80. Epub 2007 Apr 3.

Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1210/me.2006-0360DOI Listing
June 2007

FcgammaRIIB mediates C-reactive protein inhibition of endothelial NO synthase.

Circ Res 2005 Nov 3;97(11):1124-31. Epub 2005 Nov 3.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1161/01.RES.0000194323.77203.feDOI Listing
November 2005

Dissecting the basis of nongenomic activation of endothelial nitric oxide synthase by estradiol: role of ERalpha domains with known nuclear functions.

Mol Endocrinol 2005 Feb 14;19(2):277-89. Epub 2004 Oct 14.

Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1210/me.2004-0008DOI Listing
February 2005

Hypoxia-induced left ventricular dysfunction in myoglobin-deficient mice.

Am J Physiol Heart Circ Physiol 2003 Nov 24;285(5):H2132-41. Epub 2003 Jul 24.

Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8573, USA.

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http://dx.doi.org/10.1152/ajpheart.00147.2003DOI Listing
November 2003

Pulmonary NO synthase expression is attenuated in a fetal baboon model of chronic lung disease.

Am J Physiol Lung Cell Mol Physiol 2003 May 10;284(5):L749-58. Epub 2003 Jan 10.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75390, USA.

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http://dx.doi.org/10.1152/ajplung.00334.2002DOI Listing
May 2003

High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases.

J Biol Chem 2003 Mar 2;278(11):9142-9. Epub 2003 Jan 2.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1074/jbc.M211394200DOI Listing
March 2003

Vasomodulation by skeletal muscle-derived nitric oxide requires alpha-syntrophin-mediated sarcolemmal localization of neuronal Nitric oxide synthase.

Circ Res 2003 Mar 13;92(5):554-60. Epub 2003 Feb 13.

Department of Internal Medicine, Division of Hypertension, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Tex 75390-8586, USA.

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http://dx.doi.org/10.1161/01.RES.0000061570.83105.52DOI Listing
March 2003

Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells.

Circulation 2002 Sep;106(12):1439-41

Laboratory for Atherosclerosis and Metabolic Research, Department of Pathology, UC Davis Medical Center, Sacramento, Calif 95817, USA.

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http://dx.doi.org/10.1161/01.cir.0000033116.22237.f9DOI Listing
September 2002

ERbeta has nongenomic action in caveolae.

Mol Endocrinol 2002 May;16(5):938-46

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1210/mend.16.5.0827DOI Listing
May 2002