Ivan P Gorlov

Ivan P Gorlov

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Ivan P Gorlov

Ivan P Gorlov

Publications by authors named "Ivan P Gorlov"

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Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 515.33 TERT-CLPTM1Ll Region.

J Thorac Oncol 2019 Aug 19;14(8):1360-1369. Epub 2019 Apr 19.

Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193028
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http://dx.doi.org/10.1016/j.jtho.2019.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833942PMC
August 2019

Untouchable genes in the human genome: Identifying ideal targets for cancer treatment.

Cancer Genet 2019 02 24;231-232:67-79. Epub 2019 Jan 24.

Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States.

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http://dx.doi.org/10.1016/j.cancergen.2019.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727980PMC
February 2019

Gene characteristics predicting missense, nonsense and frameshift mutations in tumor samples.

BMC Bioinformatics 2018 Nov 19;19(1):430. Epub 2018 Nov 19.

The Geisel School of Medicine, Department of Biomedical Data Science, Dartmouth College, HB7936, One Medical Center Dr., Dartmouth-Hitchcock Medical Center, Beirut, NH, 03756, Lebanon.

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https://bmcbioinformatics.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12859-018-2455-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245819PMC
November 2018

Ancestry inference using principal component analysis and spatial analysis: a distance-based analysis to account for population substructure.

BMC Genomics 2017 Oct 16;18(1):789. Epub 2017 Oct 16.

Department of Biomedical Data Science, Dartmouth Geisel School of Medicine, One Medical Center Drive, Lebanon, NH, 03756, USA.

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http://dx.doi.org/10.1186/s12864-017-4166-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644186PMC
October 2017

Is age an independent risk factor for medical complications following minimally invasive radical prostatectomy? An evaluation of contemporary American College of Surgeons National Surgical Quality Improvement (ACS-NSQIP) data.

J Robot Surg 2016 Dec 4;10(4):343-346. Epub 2016 Jun 4.

Section of Urology, Department of Surgery, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, 03756, USA.

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http://dx.doi.org/10.1007/s11701-016-0605-9DOI Listing
December 2016

Prediction of the gene expression in normal lung tissue by the gene expression in blood.

BMC Med Genomics 2015 Nov 17;8:77. Epub 2015 Nov 17.

Department of Biomedical Data Science, The Geisel School of Medicine, Dartmouth College, HB7937, One Medical Center Dr., Dartmouth-Hitchcock Medical Center, Lebanon, NH, 03756, USA.

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http://dx.doi.org/10.1186/s12920-015-0152-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650316PMC
November 2015

Implementation of a Molecular Tumor Board: The Impact on Treatment Decisions for 35 Patients Evaluated at Dartmouth-Hitchcock Medical Center.

Oncologist 2015 Sep 23;20(9):1011-8. Epub 2015 Jul 23.

Departments of Pathology, Community and Family Medicine, Medicine, and Pharmacology & Toxicology, Comprehensive Breast Program, and Familial Cancer Program, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA

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http://dx.doi.org/10.1634/theoncologist.2015-0097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571816PMC
September 2015

Allelic Spectra of Risk SNPs Are Different for Environment/Lifestyle Dependent versus Independent Diseases.

PLoS Genet 2015 Jul 22;11(7):e1005371. Epub 2015 Jul 22.

The Geisel School of Medicine, Dartmouth College, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States of America.

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https://dx.plos.org/10.1371/journal.pgen.1005371
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http://dx.doi.org/10.1371/journal.pgen.1005371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511800PMC
July 2015

SNP characteristics predict replication success in association studies.

Hum Genet 2014 Dec 2;133(12):1477-86. Epub 2014 Oct 2.

Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, 74 College Street Vail 7th Floor, HB 7260 Vail, Hanover, NH, 03755, USA,

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http://dx.doi.org/10.1007/s00439-014-1493-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384517PMC
December 2014

Modified logistic regression models using gene coexpression and clinical features to predict prostate cancer progression.

Comput Math Methods Med 2013 4;2013:917502. Epub 2013 Dec 4.

School of Applied Chemistry and Biotechnology, Shenzhen Polytechnic, Shenzhen, Guangdong 518055, China.

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http://www.hindawi.com/journals/cmmm/2013/917502/
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http://dx.doi.org/10.1155/2013/917502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866878PMC
August 2014

How to get the most from microarray data: advice from reverse genomics.

BMC Genomics 2014 Mar 21;15:223. Epub 2014 Mar 21.

Department of Genitourinary Medical Oncology, Unit 1374, The University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX 77030-3721, USA.

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http://dx.doi.org/10.1186/1471-2164-15-223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997969PMC
March 2014

Building a statistical model for predicting cancer genes.

PLoS One 2012 15;7(11):e49175. Epub 2012 Nov 15.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049175PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499550PMC
May 2013

In silico functional profiling of individual prostate cancer tumors: many genes, few functions.

Cancer Genomics Proteomics 2012 May-Jun;9(3):109-14

Department of Genitourinary Medical Oncology, Unit 1374, The University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX 77030-3721, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922615PMC
November 2012

Initial medical attention on patients with early-stage non-small cell lung cancer.

PLoS One 2012 7;7(3):e32644. Epub 2012 Mar 7.

Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032644PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296738PMC
August 2012

Cryptorchidism in mice with an androgen receptor ablation in gubernaculum testis.

Mol Endocrinol 2012 Apr 9;26(4):598-607. Epub 2012 Feb 9.

Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, Miami, Florida 33199, USA.

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http://dx.doi.org/10.1210/me.2011-1283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327355PMC
April 2012

Derived SNP alleles are used more frequently than ancestral alleles as risk-associated variants in common human diseases.

J Bioinform Comput Biol 2012 Apr;10(2):1241008

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030-3721, USA.

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http://dx.doi.org/10.1142/S0219720012410089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655427PMC
April 2012

Beyond comparing means: the usefulness of analyzing interindividual variation in gene expression for identifying genes associated with cancer development.

J Bioinform Comput Biol 2012 Apr;10(2):1241013

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030-3721, USA.

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http://dx.doi.org/10.1142/S0219720012410132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893106PMC
April 2012

Association of smoking with tumor size at diagnosis in non-small cell lung cancer.

Lung Cancer 2011 Dec 8;74(3):378-83. Epub 2011 Jun 8.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.lungcan.2011.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197014PMC
December 2011

Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.

Carcinogenesis 2011 Oct 18;32(10):1493-9. Epub 2011 Jul 18.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston,TX 77030, USA.

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http://dx.doi.org/10.1093/carcin/bgr136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179422PMC
October 2011

Suppression of insulin-like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development.

Mol Endocrinol 2011 Jan 8;25(1):170-83. Epub 2010 Dec 8.

Department of Human Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, Miami, FL 33199, USA.

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http://dx.doi.org/10.1210/me.2010-0330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089031PMC
January 2011

Prioritizing genes associated with prostate cancer development.

BMC Cancer 2010 Nov 2;10:599. Epub 2010 Nov 2.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1186/1471-2407-10-599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988752PMC
November 2010

Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study.

J Natl Cancer Inst 2010 Aug 16;102(15):1199-205. Epub 2010 Jun 16.

Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/jnci/djq232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914761PMC
August 2010

Housekeeping genes in prostate tumorigenesis.

Int J Cancer 2009 Dec;125(11):2603-8

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030-4009, USA.

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http://dx.doi.org/10.1002/ijc.24680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531049PMC
December 2009

Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data.

BMC Med Genomics 2009 Aug 4;2:48. Epub 2009 Aug 4.

Department of Genitourinary Medical Oncology, The University of Texas M, D, Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1186/1755-8794-2-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731785PMC
August 2009

Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome.

BMC Genomics 2008 Jun 17;9:292. Epub 2008 Jun 17.

Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1186/1471-2164-9-292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442617PMC
June 2008

Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms.

Am J Hum Genet 2008 Jan;82(1):100-12

Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.ajhg.2007.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253956PMC
January 2008

ATM sequence variants associate with susceptibility to non-small cell lung cancer.

Int J Cancer 2007 Nov;121(10):2254-9

Department of Epidemiology, The University of Texas M.D. Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1002/ijc.22918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477817PMC
November 2007

Strength of the purifying selection against different categories of the point mutations in the coding regions of the human genome.

Hum Mol Genet 2006 Apr 24;15(7):1143-50. Epub 2006 Feb 24.

Department of Epidemiology, The University of Texas M.D Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/hmg/ddl029DOI Listing
April 2006

Predicting the oncogenicity of missense mutations reported in the International Agency for Cancer Research (IARC) mutation database on p53.

Hum Mutat 2005 Nov;26(5):446-54

Department of Epidemiology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030., USA.

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http://dx.doi.org/10.1002/humu.20242DOI Listing
November 2005

Missense mutations in cancer suppressor gene TP53 are colocalized with exonic splicing enhancers (ESEs).

Mutat Res 2004 Oct;554(1-2):175-83

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Box 189, 1515 Holcombe Boulevard, Houston 77030, USA.

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http://dx.doi.org/10.1016/j.mrfmmm.2004.04.014DOI Listing
October 2004

Polymorphisms of folate metabolic genes and susceptibility to bladder cancer: a case-control study.

Carcinogenesis 2004 Sep 29;25(9):1639-47. Epub 2004 Apr 29.

Department of Epidemiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/carcin/bgh175DOI Listing
September 2004

Missense mutations in hMLH1 and hMSH2 are associated with exonic splicing enhancers.

Am J Hum Genet 2003 Nov 1;73(5):1157-61. Epub 2003 Oct 1.

Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180494PMC
http://dx.doi.org/10.1086/378819DOI Listing
November 2003

PAX6, paired domain influences sequence recognition by the homeodomain.

J Biol Chem 2002 Dec 17;277(51):49488-94. Epub 2002 Oct 17.

Department of Biochemistry and Molecular Biology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M206478200
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http://dx.doi.org/10.1074/jbc.M206478200DOI Listing
December 2002

Mutations of the GREAT gene cause cryptorchidism.

Hum Mol Genet 2002 Sep;11(19):2309-18

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/hmg/11.19.2309DOI Listing
September 2002

A method for isolating alternatively spliced isoforms: isolation of murine Pax6 isoforms.

Anal Biochem 2002 Sep;308(2):401-4

Department of Biochemistry and Molecular Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/s0003-2697(02)00244-0DOI Listing
September 2002