Ivan Bieche

Ivan Bieche

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Ivan Bieche

Ivan Bieche

Publications by authors named "Ivan Bieche"

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Immune gene expression in head and neck squamous cell carcinoma patients.

Eur J Cancer 2019 Nov 5;121:210-223. Epub 2019 Oct 5.

Department of Drug Development and Innovation, Institut Curie, Paris & Saint-Cloud, France; INSERM U900 Research Unit, Institut Curie, Saint-Cloud, France; Versailles-Saint-Quentin-en-Yvelines University, Montigny-le-Bretonneux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.08.028DOI Listing
November 2019

P-cadherin-induced decorin secretion is required for collagen fiber alignment and directional collective cell migration.

J Cell Sci 2019 Nov 8;132(21). Epub 2019 Nov 8.

CRBM, Centre de Recherche en Biologie cellulaire de Montpellier, CNRS UMR 5237, 34000 Montpellier, France Montpellier University, 34000 Montpellier, France

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http://dx.doi.org/10.1242/jcs.233189DOI Listing
November 2019

Mechanistic Signatures of Human Papillomavirus Insertions in Anal Squamous Cell Carcinomas.

Cancers (Basel) 2019 Nov 22;11(12). Epub 2019 Nov 22.

Institut Curie, Medical Oncology Department, Versailles Saint-Quentin University, 35 rue Dailly, 92210 Saint-Cloud, France.

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http://dx.doi.org/10.3390/cancers11121846DOI Listing
November 2019

GNAS but Not Extended RAS Mutations Spectrum are Associated with a Better Prognosis in Intraductal Pancreatic Mucinous Neoplasms.

Ann Surg Oncol 2019 Aug 25;26(8):2640-2650. Epub 2019 Apr 25.

Institut National de la Santé et de la Recherche Médicale - Centre de Recherche Biomédicale Bichat Beaujon (CRI)/INSERM U1149, Clichy, France.

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http://dx.doi.org/10.1245/s10434-019-07389-6DOI Listing
August 2019

Differential gene expression in growth factors, epithelial mesenchymal transition and chemotaxis in the diffuse type compared with the intestinal type of gastric cancer.

Oncol Lett 2019 Jul 21;18(1):674-686. Epub 2019 May 21.

Department of Genetics, Pharmacogenomics Unit-Institut Curie, University of Paris-Descartes-Paris 5, 75005 Paris, France.

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http://dx.doi.org/10.3892/ol.2019.10392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546989PMC
July 2019

Precision medicine in oncology: what is it exactly and where are we?

Per Med 2018 09 27;15(5):351-353. Epub 2018 Sep 27.

Pharmacogenomics Unit, Institute Curie, Paris, France.

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http://dx.doi.org/10.2217/pme-2018-0036DOI Listing
September 2018

High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast.

Histopathology 2018 Aug 7;73(2):273-283. Epub 2018 May 7.

Institut Curie, Paris Sciences Lettres Research University, Pôle de médecine diagnostique et théranostique, Paris, France.

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http://dx.doi.org/10.1111/his.13514DOI Listing
August 2018

Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer.

Breast Cancer Res 2018 08 7;20(1):88. Epub 2018 Aug 7.

Pharmacogenomic Unit, Department of Genetics, Curie Institute, PSL Research University, 26 rue d'Ulm, 75005, Paris, France.

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http://dx.doi.org/10.1186/s13058-018-1007-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081877PMC
August 2018

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis.

Breast Cancer Res 2018 07 11;20(1):73. Epub 2018 Jul 11.

University of Lille, CNRS, Institut Pasteur de Lille, UMR 8161 - M3T - Mechanisms of Tumorigenesis and Targeted Therapies, F-59000, Lille, France.

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http://dx.doi.org/10.1186/s13058-018-0992-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042225PMC
July 2018

Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data.

J Clin Oncol 2018 04 22;36(10):981-990. Epub 2018 Feb 22.

Dimitrios Zardavas and Debora Fumagalli, Breast International Group; Christos Sotiriou, Université Libre de Bruxelles, Brussels, Belgium; Luc te Marvelde and Roger L. Milne, Cancer Council; Roger L. Milne and Sherene Loi, University of Melbourne, Melbourne; Barry Iacopetta, University of Western Australia, Western Australia; Sandra O'Toole and Elena Lopez-Knowles, Garvan Institute of Medical Research, Darlinghurst, Australia; George Fountzilas and Vassiliki Kotoula, Hellenic Foundation for Cancer Research/Aristotle University of Thessaloniki, Thessaloniki; Evangelia Razis, Hygeia Hospital; George Papaxoinis, Hippokration Hospital, Athens, Greece; Heikki Joensuu, Helsinki University Hospital and University of Helsinki, Helsinki, Finland; Mary Ellen Moynahan, Memorial Sloan Kettering Cancer Center, New York, NY; Bryan T. Hennessy, Beaumont Hospital and Royal College of Surgeons, Dublin, Ireland; Ivan Bieche, Curie Institut, Paris; Thomas Bachelot, Centre de Recherche en Cancérologie de Lyon, Lyon; Stefan Michiels, Gustave Roussy and Inserm, Univ. Paris-Sud, Univ. Paris-Saclay, Villejuif, France; Lao H. Saal, Lund University, Lund; Olle Stal, Qing Wang, and Gizeh Perez-Tenorio, Linköping University, Linköping, Sweden; Jeanette Dupont Jensen, University of Southern Denmark, on behalf of the Danish Breast Cancer Cooperative Group, Odense, Denmark; Elena Lopez-Knowles, Royal Marsden NHS Trust and Institute of Cancer Research, London; Daniel W. Rea, University of Birmingham, Birmingham, United Kingdom; Mattia Barbaraeschi, Santa Chiara Hospital, Trento, Italy; Shinzaburo Noguchi, Osaka University, Osaka Japan; Hatem A. Azim Jr, American University of Beirut (AUB), Beirut, Lebanon; Enrique Lerma, Universitat Autònoma de Barcelona, Barcelona, Spain; Cornelis J.H. can de Velde, Leiden University Medical Center, Leiden, the Netherlands; Vicky Sabine, University of Guelph, Guelph; John M.S. Bartlett, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2017.74.8301DOI Listing
April 2018

Comprehensive clinical and molecular analyses of neuroendocrine carcinomas of the breast.

Mod Pathol 2018 01 8;31(1):68-82. Epub 2017 Sep 8.

Pathology-Genetics-Immunology Department, Institut Curie, Paris Sciences Lettres Research University, Paris, France.

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http://dx.doi.org/10.1038/modpathol.2017.107DOI Listing
January 2018

HPV circulating tumor DNA to monitor the efficacy of anti-PD-1 therapy in metastatic squamous cell carcinoma of the anal canal: A case report.

Int J Cancer 2017 10 12;141(8):1667-1670. Epub 2017 Jul 12.

Department of Medical Oncology, Institut Curie, PSL Research University, Paris and Saint Cloud, France.

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http://dx.doi.org/10.1002/ijc.30863DOI Listing
October 2017

Tubulin glycylation controls primary cilia length.

J Cell Biol 2017 09 7;216(9):2701-2713. Epub 2017 Jul 7.

Institut Curie, Paris Sciences et Lettres Research University, Centre National de la Recherche Scientifique UMR3348, Orsay, France

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http://dx.doi.org/10.1083/jcb.201612050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584158PMC
September 2017

Baseline β-catenin, programmed death-ligand 1 expression and tumour-infiltrating lymphocytes predict response and poor prognosis in BRAF inhibitor-treated melanoma patients.

Eur J Cancer 2017 06 14;78:70-81. Epub 2017 Apr 14.

Unit of Medical Oncology, Department of Oncology and Hematology, Papa Giovanni XXIII Hospital, Bergamo, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.03.012DOI Listing
June 2017

The SHIVA01 trial: what have we learned?

Pharmacogenomics 2017 06 8;18(9):831-834. Epub 2017 Jun 8.

Pharmacogenomics Unit, Institut Curie, Paris, France.

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http://dx.doi.org/10.2217/pgs-2017-0062DOI Listing
June 2017

The critical role of the ZNF217 oncogene in promoting breast cancer metastasis to the bone.

J Pathol 2017 05 27;242(1):73-89. Epub 2017 Mar 27.

Univ. Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon, France.

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http://dx.doi.org/10.1002/path.4882DOI Listing
May 2017

Metabolic Response to Everolimus in Patient-Derived Triple-Negative Breast Cancer Xenografts.

J Proteome Res 2017 05 3;16(5):1868-1879. Epub 2017 Apr 3.

Department of Circulation and Medical Imaging, NTNU, The Norwegian University of Science and Technology , Trondheim 7489, Norway.

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http://dx.doi.org/10.1021/acs.jproteome.6b00918DOI Listing
May 2017

Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration.

J Cell Sci 2017 03 19;130(5):938-949. Epub 2017 Jan 19.

Institut Curie, PSL Research University, CNRS UMR3348, Orsay F-91405, France

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http://dx.doi.org/10.1242/jcs.199091DOI Listing
March 2017

Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk.

J Clin Endocrinol Metab 2016 11 30;101(11):4449-4460. Epub 2016 Aug 30.

Institut E3M-ICAN, Department of Endocrinology and Reproductive Medicine (Z.C., C.C., V.Gr., I.T., P.T.), Hôpitaux Universitaires Pitié Salpêtrière Charles Foix, Centre des Pathologies Gynécologiques Rares, Firendo, Université Pierre et Marie Curie, 75013 Paris, France; Department of Oncological Surgery (F.L.), Institut Curie, 75005 Paris, France; Inserm (M.B., I.C., A.C., N.P., S.B., F.B., P.C., J.-E.G., V.G., P.T.), U1151, Institut Necker Enfants Malades, 75993 Paris, France; Université Paris Descartes (M.B., I.C., A.C., N.P., S.B., F.B., M.F., M.D.C., R.P., J.-E. G., V.G.), Sorbonne Paris Cité, France; Department of Genetics (I.B., S.V.), Institut Curie, 75005 Paris, France; Unite de Recherche Clinique (M.-L.T., A.B.), Pitie Salpêtriere Hospital, 75013 Paris, France; Inserm (M.F., M.D.C.), U1016, Institut Cochin, 75014 Paris, France; CNRS (M.F., M.D.C., R.P.), UMR8104, Paris, France; Inter Régional pour la Santé (F.R., J.T.), La Riche, France; and Department of Pathology (B.S.-Z.), Institut Curie, 75005 Paris, France.

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http://dx.doi.org/10.1210/jc.2016-2372DOI Listing
November 2016

MicroRNA-based diagnostic tools for advanced fibrosis and cirrhosis in patients with chronic hepatitis B and C.

Sci Rep 2016 10 12;6:34935. Epub 2016 Oct 12.

INSERM, UMR1149, Team «Physiopathologie et traitements des hépatites virales», Centre de Recherche sur l'Inflammation, and Université Denis Diderot Paris 7, site Bichat, BP 416, F-75018, Paris, France.

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http://dx.doi.org/10.1038/srep34935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059729PMC
October 2016

Combination of Carboplatin and Bevacizumab Is an Efficient Therapeutic Approach in Retinoblastoma Patient-Derived Xenografts.

Invest Ophthalmol Vis Sci 2016 Sep;57(11):4916-4926

Laboratory of Preclinical Investigation, Translational Research Department, Paris Sciences et Lettres (PSL) University, Institut Curie, Paris, France 8Department of Medical Oncology, Institut Curie, Paris, France.

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http://dx.doi.org/10.1167/iovs.15-18725DOI Listing
September 2016

Long Noncoding RNAs as New Architects in Cancer Epigenetics, Prognostic Biomarkers, and Potential Therapeutic Targets.

Biomed Res Int 2015 13;2015:320214. Epub 2015 Sep 13.

UMR 3244, Non-Coding RNA, Epigenetics and Genome Fluidity, Institute Curie, 75248 Paris, France.

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http://dx.doi.org/10.1155/2015/320214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584070PMC
August 2016

Expression of ANRIL-Polycomb Complexes-CDKN2A/B/ARF Genes in Breast Tumors: Identification of a Two-Gene (EZH2/CBX7) Signature with Independent Prognostic Value.

Mol Cancer Res 2016 07 21;14(7):623-33. Epub 2016 Apr 21.

Unit of Pharmacogenomics, Department of Genetics, Curie Institute, Paris, France. Faculty of Pharmaceutical and Biological Sciences, Paris Descartes University, Paris, France.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-15
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http://dx.doi.org/10.1158/1541-7786.MCR-15-0418DOI Listing
July 2016

Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers.

Int J Cancer 2016 May 6;138(10):2510-21. Epub 2016 Jan 6.

Translational Research Department, Institut Curie, Paris, 75005, France.

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http://dx.doi.org/10.1002/ijc.29974DOI Listing
May 2016

Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets.

Blood 2016 05 10;127(18):2231-40. Epub 2016 Mar 10.

Unité Mixte de Recherche (UMR) S949 INSERM, Strasbourg, France; Etablissement Français du Sang-Alsace, Strasbourg, France; Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France; Université de Strasbourg, Strasbourg, France;

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http://dx.doi.org/10.1182/blood-2015-09-670208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859197PMC
May 2016

IFI35, mir-99a and HCV genotype to predict sustained virological response to pegylated-interferon plus ribavirin in chronic hepatitis C.

PLoS One 2015 6;10(4):e0121395. Epub 2015 Apr 6.

INSERM, UMR1149, Team «Viral hepatitis », Centre de Recherche sur l'inflammation, BP 416, Paris, France; Université Denis Diderot Paris 7, site Bichat, BP 416, Paris, France; Service d'Hépatologie, PMAD Hôpital Beaujon, 100 Bd du Général Leclerc, Clichy la Garenne, Clichy, France; Laboratory of Excellence Labex INFLAMEX, PRES Paris Sorbonne Cité, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121395PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386819PMC
April 2016

Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine Trials.

J Natl Cancer Inst 2016 Apr 23;108(4). Epub 2015 Nov 23.

Affiliations of authors:Department of Medical Oncology, Institut Curie , Paris & Saint-Cloud , France (CLT, MK, MA); EA7285 Versailles-St-Quentin-en-Yvelines University , France (CLT, RR); Investigational Cancer Therapeutics, M. D. Anderson Cancer Center , Houston, TX (AMT); Drug Development Program, Department of Medical Oncology and Hematology, Princess Margaret Hospital , Toronto , Canada (PB); Department of Genetics, Institut Curie , Paris , France (GP, CC, ER, IB); Department of Pathology, Institut Curie , Paris , France (AVS); Institut Curie / INSERM U900 , Paris , France (NS, XP); Department of Surgery, Institut Curie , Paris & Saint-Cloud , France (RR); Institut Curie, INSERM U830 , Paris , France (OD); EA7331, University of Paris-Descartes , Paris , France (IB).

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http://dx.doi.org/10.1093/jnci/djv362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830395PMC
April 2016

[Recent advances in bladder urothelial carcinogenesis].

Bull Cancer 2015 Dec 23;102(12):1020-35. Epub 2015 Nov 23.

Université Paris Descartes, institut Curie, service de génétique, unité de pharmacogénomique, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.bulcan.2015.10.004DOI Listing
December 2015

Precision medicine: lessons learned from the SHIVA trial - Authors' reply.

Lancet Oncol 2015 Dec;16(16):e581-2

Institut Curie, 92210 Saint-Cloud, Paris, France.

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http://dx.doi.org/10.1016/S1470-2045(15)00455-6DOI Listing
December 2015

Unraveling the Role of Huntingtin in Breast Cancer Metastasis.

J Natl Cancer Inst 2015 Oct 20;107(10). Epub 2015 Aug 20.

Institut Curie, Paris, France (MST, JRM, CMS, LF, SL, SV, IB, AVS, SH); CNRS UMR 3306, Orsay, France (MST, JRM, CMS, SL, SH); INSERM U1005, Orsay, France (MST, JRM, CMS, SL, SH); University Paris Sud 11, Orsay, France (MST); Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', Centre National de la Recherche Scientifique UMR5238, Université de Lyon, Lyon, France (JF, AB, PM); Department of Biostatistics and Medical Informatics, Assistance Publique-Hôpitaux de Paris (STdM); Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France (STdM); INSERM, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France (STdM); University Paris Descartes, Sorbonne Paris Cité, France (IB); Department of Pathology, Institut Curie, Paris, France (AVS); Univ. Grenoble Alpes, Grenoble Institut des Neurosciences, GIN, Grenoble, France (SH); INSERM U836, Grenoble, France (SH).

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http://dx.doi.org/10.1093/jnci/djv208DOI Listing
October 2015

High-throughput pharmacogenetics identifies SLCO1A2 polymorphisms as candidates to elucidate the risk of febrile neutropenia in the breast cancer RAPP-01 trial.

Breast Cancer Res Treat 2015 Sep 29;153(2):383-9. Epub 2015 Aug 29.

Institut Curie, Service de Génétique, Unité de Pharmacogénomique, 26 rue d'Ulm, 75005, Paris, France,

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http://dx.doi.org/10.1007/s10549-015-3552-7DOI Listing
September 2015

Design and statistical principles of the SHIVA trial.

Chin Clin Oncol 2015 Sep;4(3):32

Unité INSERM, Institut Curie, Mines ParisTech U900, Paris, France; Department of Medical Oncology, Clinical Trial Unit, Institut Curie, Paris and Saint-Cloud, France.

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http://dx.doi.org/10.3978/j.issn.2304-3865.2015.02.02DOI Listing
September 2015

The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain.

Clin Epigenetics 2015 27;7:57. Epub 2015 May 27.

Brain Tumour Research Centre, University of Wolverhampton, Wolverhampton, UK ; School of Biology, Chemistry and Forensic Sciences, University of Wolverhampton, Wolverhampton, UK ; Centre for Rare Diseases and Personalised Medicine, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1186/s13148-015-0089-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457099PMC
June 2015