Publications by authors named "Iuliana Ionita-Laza"

54Publications

Cell Type-Specific Annotation and Fine Mapping of Variants Associated With Brain Disorders.

Front Genet 2020 3;11:575928. Epub 2020 Dec 3.

Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.

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December 2020

Differences in plasma metabolites related to Alzheimer's disease, ε4 status, and ethnicity.

Alzheimers Dement (N Y) 2020 6;6(1):e12025. Epub 2020 May 6.

College of Physicians and Surgeons Taub Institute for Research on Alzheimer's Disease and the Aging Brain Columbia University New York New York.

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May 2020

Co-localization between Sequence Constraint and Epigenomic Information Improves Interpretation of Whole-Genome Sequencing Data.

Am J Hum Genet 2020 04;106(4):513-524

Department of Biostatistics, Columbia University, New York, NY 10032, USA. Electronic address:

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April 2020

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis.

Authors:
Jingyuan Xie Lili Liu Nikol Mladkova Yifu Li Hong Ren Weiming Wang Zhao Cui Li Lin Xiaofan Hu Xialian Yu Jing Xu Gang Liu Yasar Caliskan Carlo Sidore Olivia Balderes Raphael J Rosen Monica Bodria Francesca Zanoni Jun Y Zhang Priya Krithivasan Karla Mehl Maddalena Marasa Atlas Khan Fatih Ozay Pietro A Canetta Andrew S Bomback Gerald B Appel Simone Sanna-Cherchi Matthew G Sampson Laura H Mariani Agnieszka Perkowska-Ptasinska Magdalena Durlik Krzysztof Mucha Barbara Moszczuk Bartosz Foroncewicz Leszek Pączek Ireneusz Habura Elisabet Ars Jose Ballarin Laila-Yasmin Mani Bruno Vogt Savas Ozturk Abdülmecit Yildiz Nurhan Seyahi Hakki Arikan Mehmet Koc Taner Basturk Gonca Karahan Sebahat Usta Akgul Mehmet Sukru Sever Dan Zhang Domenico Santoro Mario Bonomini Francesco Londrino Loreto Gesualdo Jana Reiterova Vladimir Tesar Claudia Izzi Silvana Savoldi Donatella Spotti Carmelita Marcantoni Piergiorgio Messa Marco Galliani Dario Roccatello Simona Granata Gianluigi Zaza Francesca Lugani GianMarco Ghiggeri Isabella Pisani Landino Allegri Ben Sprangers Jin-Ho Park BeLong Cho Yon Su Kim Dong Ki Kim Hitoshi Suzuki Antonio Amoroso Daniel C Cattran Fernando C Fervenza Antonello Pani Patrick Hamilton Shelly Harris Sanjana Gupta Chris Cheshire Stephanie Dufek Naomi Issler Ruth J Pepper John Connolly Stephen Powis Detlef Bockenhauer Horia C Stanescu Neil Ashman Ruth J F Loos Eimear E Kenny Matthias Wuttke Kai-Uwe Eckardt Anna Köttgen Julia M Hofstra Marieke J H Coenen Lambertus A Kiemeney Shreeram Akilesh Matthias Kretzler Lawrence H Beck Benedicte Stengel Hanna Debiec Pierre Ronco Jack F M Wetzels Magdalena Zoledziewska Francesco Cucca Iuliana Ionita-Laza Hajeong Lee Elion Hoxha Rolf A K Stahl Paul Brenchley Francesco Scolari Ming-Hui Zhao Ali G Gharavi Robert Kleta Nan Chen Krzysztof Kiryluk

Nat Commun 2020 03 30;11(1):1600. Epub 2020 Mar 30.

Department of Medicine, Division of Nephrology, Columbia University, College of Physicians & Surgeons, New York, USA.

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March 2020

A genome-wide scan statistic framework for whole-genome sequence data analysis.

Nat Commun 2019 07 9;10(1):3018. Epub 2019 Jul 9.

Department of Biostatistics, Columbia University, New York, NY, 10032, USA.

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July 2019

Genomic Mismatch at Locus and Kidney Allograft Rejection.

N Engl J Med 2019 05;380(20):1918-1928

From the Department of Medicine, Division of Nephrology (N.J.S., Y.L., J.A.D., C.F., L.L., K.X., Y.-J.N., Y.D.N., J.Y.Z., R.S., O.B., D.B., N.O., F.O., S.G., K.M., J.W., S.M., J.R., D.J.C., J.B., A.G.G., K.K.), the Department of Surgery (L.E.R.), and the Department of Pathology and Cell Biology (E.-R.M.V., G.V., V.D.), Vagelos College of Physicians and Surgeons, and the Departments of Epidemiology (S.M.) and Biostatistics (I.I.-L.), Mailman School of Public Health, Columbia University, New York; Immunogenetics and Biology of Transplantation, Città della Salute e della Scienza, University Hospital of Turin, and Medical Genetics, Department of Medical Sciences, University of Turin, Turin (Z.D., S.D., A.A.), and the Division of Nephrology, Azienda Ospedaliera Spedali Civili of Brescia, Montichiari Hospital, University of Brescia, Brescia (F.S.) - all in Italy; the Department of Pathology, M.D. Anderson Cancer Center, Houston (F.Z.J.); the Division of Genetics and Genomics, Boston Children's Hospital, and the Department of Medical Oncology, Dana-Farber Cancer Institute, Boston (M.R.); the Department of Pediatrics, Division of Pediatric Nephrology, University of Michigan School of Medicine, Ann Arbor (C.E.G., M.G.S.); the Department of Medicine, Renal, Electrolyte, and Hypertension Division, University of Pennsylvania, Philadelphia (Y.-A.K., K.S.); the Division of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey (Y.C.); the Nephrology Research Group, Queen's University of Belfast, Belfast, United Kingdom (A.E.C., A.P.M., A.J.M.); and the Department of Internal Medicine, Division of Nephrology (S.J.L.B., M.H.B.), and the Department of Epidemiology, Unit of Genetic Epidemiology and Bioinformatics (H.S.), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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May 2019

A semi-supervised approach for predicting cell-type specific functional consequences of non-coding variation using MPRAs.

Nat Commun 2018 12 5;9(1):5199. Epub 2018 Dec 5.

Department of Biostatistics, Columbia University, New York, 10032, NY, USA.

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December 2018

Disease Heritability Inferred from Familial Relationships Reported in Medical Records.

Cell 2018 06 17;173(7):1692-1704.e11. Epub 2018 May 17.

Department of Biomedical Informatics, Columbia University, New York, NY, USA; Institute for Genomic Medicine, Columbia University, New York, NY, USA; Observational Health Data Sciences and Informatics (OHDSI), New York, NY, USA; Department of Medicine, Columbia University, New York, NY, USA; Department of Systems Biology, Columbia University, New York, NY, USA; Data Science Institute, Columbia University, New York, NY, USA. Electronic address:

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June 2018

Rare-variant association tests in longitudinal studies, with an application to the Multi-Ethnic Study of Atherosclerosis (MESA).

Genet Epidemiol 2017 12 27;41(8):801-810. Epub 2017 Oct 27.

Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.

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December 2017

Unified Sequence-Based Association Tests Allowing for Multiple Functional Annotations and Meta-analysis of Noncoding Variation in Metabochip Data.

Am J Hum Genet 2017 Sep 24;101(3):340-352. Epub 2017 Aug 24.

Department of Biostatistics, Columbia University, New York, NY 10032, USA. Electronic address:

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September 2017

QRank: a novel quantile regression tool for eQTL discovery.

Bioinformatics 2017 Jul;33(14):2123-2130

Department of Biostatistics, Columbia University, New York, NY, USA.

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July 2017

De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia.

Neuron 2016 Mar;89(5):940-7

Department of Psychiatry, Columbia University Medical Center, New York, NY 10032, USA; New York State Psychiatric Institute, New York, NY 10032, USA. Electronic address:

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March 2016

A General and Robust Framework for Secondary Traits Analysis.

Genetics 2016 Apr 19;202(4):1329-43. Epub 2016 Feb 19.

Department of Biostatistics, Columbia University, New York, New York 10032.

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April 2016

A spectral approach integrating functional genomic annotations for coding and noncoding variants.

Nat Genet 2016 Feb 4;48(2):214-20. Epub 2016 Jan 4.

Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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February 2016

Quantile Regression in the Secondary Analysis of Case-Control Data.

J Am Stat Assoc 2016 5;111(513):344-354. Epub 2016 May 5.

Department of Medicine, New York University School of Medicine, New York, NY 10016.

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May 2016