Dr. Itziar Salaverria, PhD - Institut d'Investigacions Biomèdiques August Pi i Sunyer

Dr. Itziar Salaverria

PhD

Institut d'Investigacions Biomèdiques August Pi i Sunyer

Barcelona | Spain

Main Specialties: Pediatrics

Additional Specialties: Genetics, Molecular biology, Lymphoma, pediatric lymphoma

Dr. Itziar Salaverria, PhD - Institut d'Investigacions Biomèdiques August Pi i Sunyer

Dr. Itziar Salaverria

PhD

Introduction

Primary Affiliation: Institut d'Investigacions Biomèdiques August Pi i Sunyer - Barcelona , Spain

Specialties:

Additional Specialties:

Education

Apr 2008
University of Barcelona
Doctor
Biology
Jun 2002
UAB
Biology
Genetics and Cell Biology

Publications

61Publications

3219Reads

-Profile Views

1118PubMed Central Citations

LMO2-negative Expression Predicts the Presence of MYC Translocations in Aggressive B-Cell Lymphomas.

Am J Surg Pathol 2017 Jul;41(7):877-886

*Department of Pathology, Hematopathology Unit, Hospital del Mar, Institute of Investigacions Mediques-IMIM, University Pompeu Fabra †Department of Pathology, Hematopathology Section, Hospital Clinic, Institute of Investigacions Biomediques Agust Pi Sunyer (IDIBAPS), University of Barcelona ‡Department of Pathology, Hospital de Bellvitge-IDIBELL, Hospitalet de Llobregat ¶Department of Pathology, Hospital de Sant Pau #Microarray Analysis Service, Institute of Investigacions Mediques-IMIM, Barcelona §Department of Pathology, Hospital Germans Trias i Pujol, Badalona ∥Department of Pathology, Hospital Mutua Terrassa, Terrassa, Spain **Institute of Pathology, Locarno, Switzerland.

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http://dx.doi.org/10.1097/PAS.0000000000000839DOI Listing
July 2017
126 Reads
1 Citation
5.145 Impact Factor

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism.

Cell Rep 2016 08 11;16(8):2061-2067. Epub 2016 Aug 11.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK; Division of Molecular Pathology, The Institute of Cancer Research, London SW7 3RP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999417PMC
August 2016
120 Reads
3 Citations
7.210 Impact Factor

NOTCH1, TP53, and MAP2K1 Mutations in Splenic Diffuse Red Pulp Small B-cell Lymphoma Are Associated With Progressive Disease.

Am J Surg Pathol 2016 Feb;40(2):192-201

*Hospital Clinic, Hematopathology Unit†Department of Anatomic Pathology, Universitat de Barcelona‡Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain§Pathology and Cytopathology Department, Hospital Base Puerto Montt, Puerto Montt, Chile∥Institute of Human Genetics, Christian-Albrechts-University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany¶Royal Marsden Hospital, London, UK.

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http://dx.doi.org/10.1097/PAS.0000000000000523DOI Listing
February 2016
49 Reads
5 Citations
5.145 Impact Factor

Check'-ing DLBCL.

Oncoscience 2015 8;2(2):71-2. Epub 2015 Feb 8.

Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388487PMC
http://dx.doi.org/10.18632/oncoscience.124DOI Listing
April 2015
18 Reads

Comprehensive characterization of complex structural variations in cancer by directly comparing genome sequence reads.

Nat Biotechnol 2014 Nov 26;32(11):1106-12. Epub 2014 Oct 26.

1] Joint IRB-BSC Program in Computational Biology, Barcelona Supercomputing Center, Barcelona, Spain. [2] Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

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http://dx.doi.org/10.1038/nbt.3027DOI Listing
November 2014
124 Reads
16 Citations
41.514 Impact Factor

Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma.

Oncotarget 2014 Aug;5(16):6788-800

Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Hematopathology Unit, Department of Pathology, Hospital Clínic, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196163PMC
http://dx.doi.org/10.18632/oncotarget.2253DOI Listing
August 2014
50 Reads
16 Citations
6.360 Impact Factor

Assessment of SOX11 expression in routine lymphoma tissue sections: characterization of new monoclonal antibodies for diagnosis of mantle cell lymphoma.

Am J Surg Pathol 2014 Jan;38(1):86-93

*Hematopathology Unit, Pathology Department, Hospital Clínic ‡Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) §Department of Anatomic Pathology, Pharmacology and Microbiology, University of Barcelona, Barcelona, Spain †Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland ∥Research and Development, Atlas Antibodies, Stockholm, Sweden.

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http://dx.doi.org/10.1097/PAS.0b013e3182a43996DOI Listing
January 2014
91 Reads
2 Citations
5.145 Impact Factor

Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.

Authors:
Sonja I Berndt Christine F Skibola Vijai Joseph Nicola J Camp Alexandra Nieters Zhaoming Wang Wendy Cozen Alain Monnereau Sophia S Wang Rachel S Kelly Qing Lan Lauren R Teras Nilanjan Chatterjee Charles C Chung Meredith Yeager Angela R Brooks-Wilson Patricia Hartge Mark P Purdue Brenda M Birmann Bruce K Armstrong Pierluigi Cocco Yawei Zhang Gianluca Severi Anne Zeleniuch-Jacquotte Charles Lawrence Laurie Burdette Jeffrey Yuenger Amy Hutchinson Kevin B Jacobs Timothy G Call Tait D Shanafelt Anne J Novak Neil E Kay Mark Liebow Alice H Wang Karin E Smedby Hans-Olov Adami Mads Melbye Bengt Glimelius Ellen T Chang Martha Glenn Karen Curtin Lisa A Cannon-Albright Brandt Jones W Ryan Diver Brian K Link George J Weiner Lucia Conde Paige M Bracci Jacques Riby Elizabeth A Holly Martyn T Smith Rebecca D Jackson Lesley F Tinker Yolanda Benavente Nikolaus Becker Paolo Boffetta Paul Brennan Lenka Foretova Marc Maynadie James McKay Anthony Staines Kari G Rabe Sara J Achenbach Celine M Vachon Lynn R Goldin Sara S Strom Mark C Lanasa Logan G Spector Jose F Leis Julie M Cunningham J Brice Weinberg Vicki A Morrison Neil E Caporaso Aaron D Norman Martha S Linet Anneclaire J De Roos Lindsay M Morton Richard K Severson Elio Riboli Paolo Vineis Rudolph Kaaks Dimitrios Trichopoulos Giovanna Masala Elisabete Weiderpass María-Dolores Chirlaque Roel C H Vermeulen Ruth C Travis Graham G Giles Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Jacqueline Clavel Tongzhang Zheng Theodore R Holford Kenneth Offit Andrew Zelenetz Robert J Klein John J Spinelli Kimberly A Bertrand Francine Laden Edward Giovannucci Peter Kraft Anne Kricker Jenny Turner Claire M Vajdic Maria Grazia Ennas Giovanni M Ferri Lucia Miligi Liming Liang Joshua Sampson Simon Crouch Ju-Hyun Park Kari E North Angela Cox John A Snowden Josh Wright Angel Carracedo Carlos Lopez-Otin Silvia Bea Itziar Salaverria David Martin-Garcia Elias Campo Joseph F Fraumeni Silvia de Sanjose Henrik Hjalgrim James R Cerhan Stephen J Chanock Nathaniel Rothman Susan L Slager

Nat Genet 2013 Aug 16;45(8):868-76. Epub 2013 Jun 16.

Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ng.2652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729927PMC
August 2013
145 Reads
68 Citations
29.352 Impact Factor

Recurrent loss of heterozygosity in 1p36 associated with TNFRSF14 mutations in IRF4 translocation negative pediatric follicular lymphomas.

Haematologica 2013 Aug 26;98(8):1237-41. Epub 2013 Feb 26.

Institute of Human Genetics, University Hospital Schleswig-Holstein Campus Kiel/Christian-Albrechts University Kiel, Kiel, Germany.

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http://dx.doi.org/10.3324/haematol.2012.073916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729904PMC
August 2013
40 Reads
11 Citations
5.870 Impact Factor

Follicular lymphomas in children and young adults: a comparison of the pediatric variant with usual follicular lymphoma.

Am J Surg Pathol 2013 Mar;37(3):333-43

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1097/PAS.0b013e31826b9b57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566339PMC
March 2013
14 Reads
10 Citations
5.145 Impact Factor

High resolution copy number analysis of IRF4 translocation-positive diffuse large B-cell and follicular lymphomas.

Genes Chromosomes Cancer 2013 Feb 17;52(2):150-5. Epub 2012 Oct 17.

Institute of Human Genetics, University Hospital Schleswig-Holstein Campus Kiel/Christian-Albrechts University, Kiel, Germany.

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http://dx.doi.org/10.1002/gcc.22014DOI Listing
February 2013
58 Reads
2 Citations
4.041 Impact Factor

The CBFA2T3/ACSF3 locus is recurrently involved in IGH chromosomal translocation t(14;16)(q32;q24) in pediatric B-cell lymphoma with germinal center phenotype.

Genes Chromosomes Cancer 2012 Apr;51(4):338-43

Institute of Human Genetics, University Hospital Schleswig-Holstein Campus Kiel/Christian-Albrechts University, Kiel, Germany.

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April 2012
21 Reads
7 Citations
4.041 Impact Factor

Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma.

Blood 2012 Feb 11;119(8):1882-7. Epub 2012 Jan 11.

Department of Pathology, Hematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Campus Kiel/University of Kiel, Kiel, Germany.

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http://dx.doi.org/10.1182/blood-2011-10-388470DOI Listing
February 2012
10 Reads
27 Citations
10.452 Impact Factor

The complex landscape of genetic alterations in mantle cell lymphoma.

Semin Cancer Biol 2011 Nov 18;21(5):322-34. Epub 2011 Sep 18.

Institut d'Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Hematopathology Section, Hospital Clínic, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.semcancer.2011.09.007DOI Listing
November 2011
12 Reads
17 Citations
9.330 Impact Factor

Follicular lymphoma grade 3B is a distinct neoplasm according to cytogenetic and immunohistochemical profiles.

Haematologica 2011 Sep 9;96(9):1327-34. Epub 2011 Jun 9.

Departement of Clinical Pathology, Robert-Bosch-Hospital, Stuttgart, Germany.

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http://dx.doi.org/10.3324/haematol.2011.042531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166103PMC
September 2011
38 Reads
9 Citations
5.870 Impact Factor

Follicular lymphoma grade 3B.

Best Pract Res Clin Haematol 2011 Jun 13;24(2):111-9. Epub 2011 Apr 13.

Institute of Human Genetics, University Hospital Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Schwanenweg 24, D-24105 Kiel, Germany.

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http://dx.doi.org/10.1016/j.beha.2011.02.002DOI Listing
June 2011
10 Reads
2 Citations
2.120 Impact Factor

The gray zone between Burkitt's lymphoma and diffuse large B-cell lymphoma from a genetics perspective.

J Clin Oncol 2011 May 11;29(14):1835-43. Epub 2011 Apr 11.

Institute of Human Genetics, University Hospital Schleswig-Holstein, Campus Kiel/Christian-Albrechts-University Kiel, Schwanenweg 24 D-24105 Kiel, Germany.

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http://dx.doi.org/10.1200/JCO.2010.32.8385DOI Listing
May 2011
43 Reads
26 Citations
18.430 Impact Factor

Clinical, pathological and genetic features of primary mediastinal large B-cell lymphomas and mediastinal gray zone lymphomas in children.

Haematologica 2011 Feb 22;96(2):262-8. Epub 2010 Oct 22.

Department of Pathology, Hematopathology Section and Lymph Node Registry, Christian-Albrechts-University Kiel, University Hospital Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.3324/haematol.2010.030809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031694PMC
February 2011
21 Reads
8 Citations
5.870 Impact Factor

MicroRNA expression, chromosomal alterations, and immunoglobulin variable heavy chain hypermutations in Mantle cell lymphomas.

Cancer Res 2009 Sep 18;69(17):7071-8. Epub 2009 Aug 18.

Department of Pathology (Hematopathology Unit), Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1095DOI Listing
September 2009
24 Reads
19 Citations
9.330 Impact Factor

Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling.

Blood 2009 Mar 4;113(13):3059-69. Epub 2008 Nov 4.

Hematopathology Unit, Department of Pathology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1182/blood-2008-07-170183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662646PMC
March 2009
37 Reads
53 Citations
10.452 Impact Factor

Multiple recurrent chromosomal breakpoints in mantle cell lymphoma revealed by a combination of molecular cytogenetic techniques.

Genes Chromosomes Cancer 2008 Dec;47(12):1086-97

Department of Pathology, Hematopathology Unit, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/gcc.20609DOI Listing
December 2008
45 Reads
8 Citations
4.041 Impact Factor

Genomic profiling reveals different genetic aberrations in systemic ALK-positive and ALK-negative anaplastic large cell lymphomas.

Br J Haematol 2008 Mar;140(5):516-26

Haematopathology Section, Department of Pathology, Hospital Clinic, Istitute d'Inverstigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06924.xDOI Listing
March 2008
57 Reads
23 Citations
4.711 Impact Factor

Gene expression profile and genomic changes in disease progression of early-stage chronic lymphocytic leukemia.

Haematologica 2008 Jan;93(1):132-6

Hematopathology Section, Department of Pathology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3324/haematol.11694DOI Listing
January 2008
36 Reads
2 Citations
5.870 Impact Factor

Leukemic involvement is a common feature in mantle cell lymphoma.

Cancer 2007 Jun;109(12):2473-80

Department of Hematology, Hospital Clinic, University of Barcelona, IDIBAPS, Barcelona, Spain.

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http://dx.doi.org/10.1002/cncr.22715DOI Listing
June 2007
24 Reads
13 Citations
4.890 Impact Factor

Unbalanced expression of licensing DNA replication factors occurs in a subset of mantle cell lymphomas with genomic instability.

Int J Cancer 2006 Dec;119(12):2768-74

Genomics Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.22146DOI Listing
December 2006
23 Reads
10 Citations
5.085 Impact Factor

Genomic imbalances and patterns of karyotypic variability in mantle-cell lymphoma cell lines.

Leuk Res 2006 Aug 31;30(8):923-34. Epub 2006 Jan 31.

Departament de Biologia Cellular, Fisiologia i Immunologia and Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

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http://dx.doi.org/10.1016/j.leukres.2005.11.013DOI Listing
August 2006
20 Reads
11 Citations
2.351 Impact Factor

Analysis of Aurora-A and hMPS1 mitotic kinases in mantle cell lymphoma.

Int J Cancer 2006 Jan;118(2):357-63

Department of Pathology, Hospital Clinic, Institut d'Investigacións Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.21370DOI Listing
January 2006
18 Reads
8 Citations
5.085 Impact Factor

Mantle cell lymphoma: from pathology and molecular pathogenesis to new therapeutic perspectives.

Haematologica 2006 Jan;91(1):11-6

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January 2006
9 Reads
15 Citations
5.870 Impact Factor

Frequent polymorphic changes but not mutations of TRAIL receptors DR4 and DR5 in mantle cell lymphoma and other B-cell lymphoid neoplasms.

Haematologica 2004 Nov;89(11):1322-31

Hematopathology Section, Laboratory of Pathology, Hematology Department, Hospital Clínic, Institut d'Investigacions Biomediques August Pi ISunyer, University of Barcelona, Barcelona, Spain.

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November 2004
30 Reads
3 Citations
5.870 Impact Factor

Clinicopathologic significance and prognostic value of chromosomal imbalances in diffuse large B-cell lymphomas.

J Clin Oncol 2004 Sep;22(17):3498-506

Laboratory of Pathology and Hematology Department, Hospital Clínic, Institut d'Investigactions Biomediques August Pi I Sunyer, University of Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2004.11.025DOI Listing
September 2004
27 Reads
21 Citations
18.430 Impact Factor

Top co-authors

Silvia Bea
Silvia Bea

IDIBAPS

27
Reiner Siebert
Reiner Siebert

Institute of Human Genetics

25
Elias Campo
Elias Campo

Hospital Clinic

24
German Ott
German Ott

Department of Clinical Pathology

18
Andreas Rosenwald
Andreas Rosenwald

Institute of Pathology

18
Elias Campo
Elias Campo

Hospital Clinic

16
Dolors Colomer
Dolors Colomer

Hospital Clínic

15
Alba Navarro
Alba Navarro

Hospital Clínic

14
Elaine S Jaffe
Elaine S Jaffe

Laboratory of Pathology

13
Pedro Jares
Pedro Jares

Hospital Clínic

12