Ituro Inoue

Ituro Inoue

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Ituro Inoue

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Different mutation profiles between epithelium and stroma in endometriosis and normal endometrium.

Hum Reprod 2019 Oct;34(10):1899-1905

Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.

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http://dx.doi.org/10.1093/humrep/dez155DOI Listing
October 2019

Exploration of intermediate-sized INDELs by next-generation multigene panel testing in Han Chinese patients with breast cancer.

Hum Genome Var 2019 29;6:51. Epub 2019 Oct 29.

3Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.

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http://dx.doi.org/10.1038/s41439-019-0080-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820797PMC
October 2019

Concurrent isolated retroperitoneal HGSC and STIC defined by somatic mutation analysis: a case report.

Diagn Pathol 2019 Feb 11;14(1):17. Epub 2019 Feb 11.

Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, 951-8510, Japan.

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http://dx.doi.org/10.1186/s13000-019-0795-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371506PMC
February 2019

High Order Formation and Evolution of Hornerin in Primates.

Genome Biol Evol 2018 12 1;10(12):3167-3175. Epub 2018 Dec 1.

Department of Genetics School of Life Sciences, SOKENDAI (Graduate University for Advanced Studies), Mishima, Japan.

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http://dx.doi.org/10.1093/gbe/evy208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280949PMC
December 2018

Novel MXD4-NUTM1 fusion transcript identified in primary ovarian undifferentiated small round cell sarcoma.

Genes Chromosomes Cancer 2018 11;57(11):557-563

Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1002/gcc.22668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221051PMC
November 2018

No novel, high penetrant gene might remain to be found in Japanese patients with unknown MODY.

J Hum Genet 2018 Jul 18;63(7):821-829. Epub 2018 Apr 18.

Department of Diabetes and Endocrinology, Graduate School of Medicine, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.1038/s10038-018-0449-4DOI Listing
July 2018

Comprehensive microbiome analysis of tonsillar crypts in IgA nephropathy.

Nephrol Dial Transplant 2017 Dec;32(12):2072-2079

Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://ndt.oxfordjournals.org/content/early/2016/09/27/ndt.g
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http://dx.doi.org/10.1093/ndt/gfw343DOI Listing
December 2017

Identification of a novel variant of the RET proto-oncogene in a novel family with Hirschsprung's disease.

Pediatr Surg Int 2017 Oct 10;33(10):1041-1046. Epub 2017 Aug 10.

Department of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan.

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http://dx.doi.org/10.1007/s00383-017-4134-zDOI Listing
October 2017

Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses.

PLoS Genet 2017 Jul 12;13(7):e1006883. Epub 2017 Jul 12.

Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka, Japan.

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http://dx.doi.org/10.1371/journal.pgen.1006883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529029PMC
July 2017

Rapid and cost-effective high-throughput sequencing for identification of germline mutations of BRCA1 and BRCA2.

J Hum Genet 2017 Apr 9;62(5):561-567. Epub 2017 Feb 9.

Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Shizuoka, Japan.

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http://dx.doi.org/10.1038/jhg.2017.5DOI Listing
April 2017

Comprehensive genetic testing approach for major inherited kidney diseases, using next-generation sequencing with a custom panel.

Clin Exp Nephrol 2017 Feb 26;21(1):63-75. Epub 2016 Feb 26.

Department of Nephrology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo, Tokyo, 113-8519, Japan.

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http://dx.doi.org/10.1007/s10157-016-1252-1DOI Listing
February 2017

A partial nuclear genome of the Jomons who lived 3000 years ago in Fukushima, Japan.

J Hum Genet 2017 Feb 1;62(2):213-221. Epub 2016 Sep 1.

Department of Genetics, School of Life Science, SOKENDAI (Graduate University for Advanced Studies), Mishima, Japan.

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http://dx.doi.org/10.1038/jhg.2016.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285490PMC
February 2017

Structure and evolution of the filaggrin gene repeated region in primates.

BMC Evol Biol 2017 01 11;17(1):10. Epub 2017 Jan 11.

Department of Genetics, School of Life Sciences, Graduate University for Advanced Studies (SOKENDAI), Mishima, 411-8540, Japan.

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http://dx.doi.org/10.1186/s12862-016-0851-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225520PMC
January 2017

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.

J Am Heart Assoc 2016 07 14;5(7). Epub 2016 Jul 14.

Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands

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http://dx.doi.org/10.1161/JAHA.115.002603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015357PMC
July 2016

Novel kinase fusion transcripts found in endometrial cancer.

Sci Rep 2015 Dec 22;5:18657. Epub 2015 Dec 22.

Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1038/srep18657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687039PMC
December 2015

Distribution of HLA haplotypes across Japanese Archipelago: similarity, difference and admixture.

J Hum Genet 2015 Nov 23;60(11):683-90. Epub 2015 Jul 23.

Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Shizuoka, Japan.

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http://dx.doi.org/10.1038/jhg.2015.90DOI Listing
November 2015

The impact of next-generation sequencing technologies on HLA research.

J Hum Genet 2015 Nov 27;60(11):665-73. Epub 2015 Aug 27.

Division of Human Genetics, National Institute of Genetics, Shizuoka, Japan.

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http://dx.doi.org/10.1038/jhg.2015.102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660052PMC
November 2015

Unique characteristics of the Ainu population in Northern Japan.

J Hum Genet 2015 Oct 16;60(10):565-71. Epub 2015 Jul 16.

Division of Population Genetics, National Institute of Genetics, Mishima, Japan.

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http://dx.doi.org/10.1038/jhg.2015.79DOI Listing
October 2015

Aggregation of rare/low-frequency variants of the mitochondria respiratory chain-related proteins in rheumatoid arthritis patients.

J Hum Genet 2015 Aug 28;60(8):449-54. Epub 2015 May 28.

Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan.

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http://dx.doi.org/10.1038/jhg.2015.50DOI Listing
August 2015

Genome-wide linkage and exome analyses identify variants of HMCN1 for splenic epidermoid cyst.

BMC Med Genet 2014 Oct 23;15:115. Epub 2014 Oct 23.

Division of Human Genetics, National Institute of Genetics, The Graduate University for Advanced Studies (SOKENDAI), Yata 1111, Mishima 411-8540, Shizuoka, Japan.

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http://dx.doi.org/10.1186/s12881-014-0115-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258954PMC
October 2014

Gene expression profiling reveals distinct molecular signatures associated with the rupture of intracranial aneurysm.

Stroke 2014 Aug 17;45(8):2239-45. Epub 2014 Jun 17.

From the Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan (H.N., K.H., I.I.); Department of Human Genetics, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan (A.T.); Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical University, Tokyo, Japan (T.Y., H.K.); and Department of Neurosurgery, School of Medicine, Showa University, Tokyo, Japan (T.M.).

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.114.005851
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http://dx.doi.org/10.1161/STROKEAHA.114.005851DOI Listing
August 2014

A Bead-based Normalization for Uniform Sequencing depth (BeNUS) protocol for multi-samples sequencing exemplified by HLA-B.

BMC Genomics 2014 Aug 4;15:645. Epub 2014 Aug 4.

Division of Human Genetics, National Institute of Genetics, 1111 Yata, Mishima, 411-8540 Shizuoka, Japan.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-15-645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133082PMC
August 2014

HLA-DPB1*04:01 allele is associated with non-obstructive azoospermia in Japanese patients.

Hum Genet 2013 Dec 10;132(12):1405-11. Epub 2013 Aug 10.

Division of Human Genetics, National Institute of Genetics, Yata 1111, Mishima, 411-8540, Japan,

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http://dx.doi.org/10.1007/s00439-013-1347-7DOI Listing
December 2013

A nonsynonymous variant of IL1A is associated with endometriosis in Japanese population.

J Hum Genet 2013 Aug 2;58(8):517-20. Epub 2013 May 2.

Department of Obstetrics and Gynecology, Niigata University Graduate School of Medicine and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1038/jhg.2013.32DOI Listing
August 2013

Improved loop-mediated isothermal amplification for HLA-DRB1 genotyping using RecA and a restriction enzyme for enhanced amplification specificity.

Immunogenetics 2013 Jun 9;65(6):405-15. Epub 2013 Mar 9.

Department of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, School of Medicine, Tokai University, Isehara, Kanagawa, Japan.

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http://link.springer.com/content/pdf/10.1007/s00251-013-0690
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http://link.springer.com/10.1007/s00251-013-0690-0
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http://dx.doi.org/10.1007/s00251-013-0690-0DOI Listing
June 2013

Phase-defined complete sequencing of the HLA genes by next-generation sequencing.

BMC Genomics 2013 May 28;14:355. Epub 2013 May 28.

Division of Human Genetics, National Institute of Genetics, Shizuoka, Japan.

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http://dx.doi.org/10.1186/1471-2164-14-355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671147PMC
May 2013

Exome sequencing identifies novel rheumatoid arthritis-susceptible variants in the BTNL2.

J Hum Genet 2013 Apr 31;58(4):210-5. Epub 2013 Jan 31.

Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Isehara, Japan.

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http://dx.doi.org/10.1038/jhg.2013.2DOI Listing
April 2013

Replication study and meta-analysis of human nonobstructive azoospermia in Japanese populations.

Biol Reprod 2013 Apr 11;88(4):87. Epub 2013 Apr 11.

Department of Pharmaceutical Information Science, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Tokushima, Japan.

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http://dx.doi.org/10.1095/biolreprod.112.106377DOI Listing
April 2013

Next-generation sequencing: impact of exome sequencing in characterizing Mendelian disorders.

J Hum Genet 2012 Oct 26;57(10):621-32. Epub 2012 Jul 26.

Division of Human Genetics, National Institute of Genetics, Mishima, Japan.

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http://www.nature.com/articles/jhg201291
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http://dx.doi.org/10.1038/jhg.2012.91DOI Listing
October 2012

Simple cloning strategy using GFPuv gene as positive/negative indicator.

Anal Biochem 2011 Sep 5;416(2):237-9. Epub 2011 May 5.

Department of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.

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http://dx.doi.org/10.1016/j.ab.2011.04.040DOI Listing
September 2011

Exact break point of a 50 kb deletion 8 kb centromeric of the HLA-A locus with HLA-A*24:02: the same deletion observed in other A*24 alleles and A*23:01 allele.

Immunogenetics 2011 Aug 26;63(8):467-74. Epub 2011 Apr 26.

Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Shimokasuya, Isehara, Kanagawa, Japan.

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http://link.springer.com/10.1007/s00251-011-0521-0
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http://dx.doi.org/10.1007/s00251-011-0521-0DOI Listing
August 2011

Exome resequencing combined with linkage analysis identifies novel PTH1R variants in primary failure of tooth eruption in Japanese.

J Bone Miner Res 2011 Jul;26(7):1655-61

Department of Orthodontics, School of Dentistry, Showa University, Tokyo, Japan.

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http://dx.doi.org/10.1002/jbmr.385DOI Listing
July 2011

Particular human leukocyte antigen alleles are associated with biochemical traits in the Japanese population.

Hum Immunol 2011 Jul 8;72(7):566-70. Epub 2011 Apr 8.

Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Kanagawa, Japan.

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http://dx.doi.org/10.1016/j.humimm.2011.03.011DOI Listing
July 2011

Germline copy number variations in BRCA1-associated ovarian cancer patients.

Genes Chromosomes Cancer 2011 Mar 7;50(3):167-77. Epub 2010 Dec 7.

Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1002/gcc.20841DOI Listing
March 2011

Meta-analysis of genome-wide association scans for genetic susceptibility to endometriosis in Japanese population.

J Hum Genet 2010 Dec 16;55(12):816-21. Epub 2010 Sep 16.

Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, Japan.

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http://dx.doi.org/10.1038/jhg.2010.118DOI Listing
December 2010

Genome-wide association analysis of copy number variations in subarachnoid aneurysmal hemorrhage.

J Hum Genet 2010 Nov 12;55(11):726-30. Epub 2010 Aug 12.

Laboratory of Genomic Diversity, Department of Life Science, Sogang University, Shinsu-dong, Mapo-gu, Seoul, Republic of Korea.

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http://dx.doi.org/10.1038/jhg.2010.97DOI Listing
November 2010

Genetics of Moyamoya disease.

J Hum Genet 2010 Nov 26;55(11):711-6. Epub 2010 Aug 26.

Department of Neurosurgery, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1038/jhg.2010.103DOI Listing
November 2010

Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms.

J Hum Genet 2010 Oct 8;55(10):656-61. Epub 2010 Jul 8.

Department of Molecular Life Sciences, Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Kanagawa, Japan.

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http://dx.doi.org/10.1038/jhg.2010.82DOI Listing
October 2010

TRIM39 and RNF39 are associated with Behçet's disease independently of HLA-B∗51 and -A∗26.

Biochem Biophys Res Commun 2010 Oct 27;401(4):533-7. Epub 2010 Sep 27.

Department of Molecular Life Science, Tokai University School of Medicine, Isehara, Kanagawa 259-1143, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2010.09.088DOI Listing
October 2010

ANRIL is implicated in the regulation of nucleus and potential transcriptional target of E2F1.

Oncol Rep 2010 Sep;24(3):701-7

Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Japan.

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http://dx.doi.org/10.3892/or_00000910DOI Listing
September 2010

Differential effects of chromosome 9p21 variation on subphenotypes of intracranial aneurysm: site distribution.

Stroke 2010 Aug 1;41(8):1593-8. Epub 2010 Jul 1.

Division of Molecular Life Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan.

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http://dx.doi.org/10.1161/STROKEAHA.110.586529DOI Listing
August 2010

[Genome informatics].

Nihon Rinsho 2010 Aug;68 Suppl 8:93-9

Division of Molecular Life Science, School of Medicine, Tokai University.

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August 2010

Meta-analysis of genetic association studies: methodologies, between-study heterogeneity and winner's curse.

J Hum Genet 2009 Nov 23;54(11):615-23. Epub 2009 Oct 23.

Division of Molecular Life Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan.

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http://dx.doi.org/10.1038/jhg.2009.95DOI Listing
November 2009

Further evidence for an association between mandibular height and the growth hormone receptor gene in a Japanese population.

Am J Orthod Dentofacial Orthop 2009 Oct;136(4):536-41

Department of Orthodontics, School of Dentistry, Showa University, Tokyo, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S088954060900629
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http://dx.doi.org/10.1016/j.ajodo.2007.10.054DOI Listing
October 2009

Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort.

Cerebrovasc Dis 2009 5;28(2):131-4. Epub 2009 Jun 5.

Department of Neurology, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.

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http://dx.doi.org/10.1159/000223438DOI Listing
September 2009

Genome-wide association database developed in the Japanese Integrated Database Project.

J Hum Genet 2009 Sep 24;54(9):543-6. Epub 2009 Jul 24.

Central Research Laboratory, Hitachi Ltd, Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2009.68DOI Listing
September 2009

Regulation of the hepatitis C virus genome replication by miR-199a.

J Hepatol 2009 Mar 9;50(3):453-60. Epub 2008 Jul 9.

Center for Genomic Medicine, Kyoto University, Shogoin-Kawaharacho, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.jhep.2008.06.010DOI Listing
March 2009

Identification of SNP markers for common CNV regions and association analysis of risk of subarachnoid aneurysmal hemorrhage in Japanese population.

Biochem Biophys Res Commun 2008 Sep 2;373(4):593-6. Epub 2008 Jul 2.

Department of Genetic Epidemiology, SNP Genetics, Inc., Room 1407, Complex B, WooLim Lion's Valley, 371-28, Gasan-Dong, Geumcheon-Gu, Seoul 153-801, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2008.06.083DOI Listing
September 2008

Evaluating the performance of Affymetrix SNP Array 6.0 platform with 400 Japanese individuals.

BMC Genomics 2008 Sep 22;9:431. Epub 2008 Sep 22.

Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1186/1471-2164-9-431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566316PMC
September 2008

Expressed sequence tags from cynomolgus monkey (Macaca fascicularis) liver: a systematic identification of drug-metabolizing enzymes.

FEBS Lett 2008 Jan 31;582(2):351-8. Epub 2007 Dec 31.

Division of Genetic Diagnosis, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan.

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http://doi.wiley.com/10.1016/j.febslet.2007.12.031
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http://dx.doi.org/10.1016/j.febslet.2007.12.031DOI Listing
January 2008

Citrin/mitochondrial glycerol-3-phosphate dehydrogenase double knock-out mice recapitulate features of human citrin deficiency.

J Biol Chem 2007 Aug 25;282(34):25041-52. Epub 2007 Jun 25.

Department of Molecular Metabolism and Biochemical Genetics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.

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http://dx.doi.org/10.1074/jbc.M702031200DOI Listing
August 2007

Identification of FAZF as a novel BMP2-induced transcription factor during osteoblastic differentiation.

J Cell Biochem 2007 May;101(1):147-54

Department of Clinical Pharmacy and pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1002/jcb.21165DOI Listing
May 2007

The alanine/threonine polymorphism of the alpha-1-antichymotrypsin (SERPINA3) gene and ruptured intracranial aneurysms in the Japanese population.

Cerebrovasc Dis 2007 12;23(1):46-9. Epub 2006 Sep 12.

Division of Genetic Diagnosis, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1159/000095758DOI Listing
March 2007

ADAM33 polymorphisms are associated with aspirin-intolerant asthma in the Japanese population.

J Hum Genet 2007 24;52(1):66-72. Epub 2006 Oct 24.

Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Niigata, 951-8510, Japan.

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http://dx.doi.org/10.1007/s10038-006-0081-6DOI Listing
March 2007

Using endothelial nitric oxide synthase gene polymorphisms to identify intracranial aneurysms more prone to rupture in Japanese patients.

J Neurosurg 2006 Nov;105(5):717-22

Division of Genetic Diagnosis, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.3171/jns.2006.105.5.717DOI Listing
November 2006

The small heat shock protein alphaB-crystallin inhibits differentiation-induced caspase 3 activation and myogenic differentiation.

Biol Pharm Bull 2006 Sep;29(9):1815-9

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan.

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http://dx.doi.org/10.1248/bpb.29.1815DOI Listing
September 2006

The genetics of intracranial aneurysms.

J Hum Genet 2006 31;51(7):587-94. Epub 2006 May 31.

Division of Genetic Diagnosis, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Tokyo 108-8639, Japan.

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http://surgicalneurologyint.com/wp-content/uploads/2015/07/t
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http://link.springer.com/content/pdf/10.1007/s10038-006-0407
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http://www.nature.com/doifinder/10.1007/s10038-006-0407-4
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http://dx.doi.org/10.1007/s10038-006-0407-4DOI Listing
August 2006