Italo Tempera

Italo Tempera

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Italo Tempera

Italo Tempera

Publications by authors named "Italo Tempera"

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Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1.

PLoS Pathog 2018 11 5;14(11):e1007394. Epub 2018 Nov 5.

Fels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States of America.

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http://dx.plos.org/10.1371/journal.ppat.1007394
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http://dx.doi.org/10.1371/journal.ppat.1007394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237423PMC
November 2018

PARP1 Stabilizes CTCF Binding and Chromatin Structure To Maintain Epstein-Barr Virus Latency Type.

J Virol 2018 09 29;92(18). Epub 2018 Aug 29.

Fels Institute for Cancer Research & Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA

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http://jvi.asm.org/lookup/doi/10.1128/JVI.00755-18
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http://dx.doi.org/10.1128/JVI.00755-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146685PMC
September 2018

Poly(ADP-ribose) Polymerase 1, PARP1, modifies EZH2 and inhibits EZH2 histone methyltransferase activity after DNA damage.

Oncotarget 2018 Feb 24;9(12):10585-10605. Epub 2018 Jan 24.

Fels Institute for Cancer Research & Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.

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http://dx.doi.org/10.18632/oncotarget.24291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828221PMC
February 2018

Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of CTLA-4.

Cancer Res 2018 01 17;78(2):436-450. Epub 2017 Nov 17.

Fels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771950PMC
January 2018

Poly(ADP-ribosylated) proteins in mononuclear cells from patients with type 2 diabetes identified by proteomic studies.

Acta Diabetol 2017 Sep 12;54(9):833-842. Epub 2017 Jun 12.

Departments of Biochemical Sciences and of Experimental Medicine, Sapienza University of Roma, Rome, Italy.

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http://dx.doi.org/10.1007/s00592-017-1013-yDOI Listing
September 2017

PARP1 restricts Epstein Barr Virus lytic reactivation by binding the BZLF1 promoter.

Virology 2017 07 26;507:220-230. Epub 2017 Apr 26.

Fels Institute for Cancer Research & Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2017.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521201PMC
July 2017

HIV-1 Vpr disrupts mitochondria axonal transport and accelerates neuronal aging.

Neuropharmacology 2017 05 14;117:364-375. Epub 2017 Feb 14.

Molecular Studies of Neurodegenerative Diseases Lab, United States; Department of Neurology, The Fels Institute for Cancer Research & Molecular Biology, United States; Temple University School of Medicine, Philadelphia, PA 19140, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2017.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397298PMC
May 2017

Novel STIM1-dependent control of Ca2+ clearance regulates NFAT activity during T-cell activation.

FASEB J 2016 11 15;30(11):3878-3886. Epub 2016 Aug 15.

Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA;

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http://dx.doi.org/10.1096/fj.201600532RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067253PMC
November 2016

Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1.

J Virol 2016 10 12;90(19):8520-30. Epub 2016 Sep 12.

Department of Microbiology and Immunology, Fels Institute for Cancer Research, Temple University School of Medicine, Philadelphia, Pennsylvania, USA

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http://jvi.asm.org/lookup/doi/10.1128/JVI.01180-16
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http://dx.doi.org/10.1128/JVI.01180-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021435PMC
October 2016

Alterations in nuclear structure promote lupus autoimmunity in a mouse model.

Dis Model Mech 2016 08 9;9(8):885-97. Epub 2016 Jun 9.

Section of Rheumatology, Temple University School of Medicine, Philadelphia, PA 19140, USA

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http://dx.doi.org/10.1242/dmm.024851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007980PMC
August 2016

Global Transcriptome Analysis Reveals That Poly(ADP-Ribose) Polymerase 1 Regulates Gene Expression through EZH2.

Mol Cell Biol 2015 Dec 14;35(23):3934-44. Epub 2015 Sep 14.

Fels Institute for Cancer and Molecular Biology, Temple University, Philadelphia, Pennsylvania, USA Department of Microbiology and Immunology, Temple University, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1128/MCB.00635-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628063PMC
December 2015

Epigenetic regulation of EBV persistence and oncogenesis.

Semin Cancer Biol 2014 Jun 24;26:22-9. Epub 2014 Jan 24.

The Wistar Institute, Philadelphia, PA 19140, United States. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2014.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048758PMC
June 2014

CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation.

Nucleic Acids Res 2014 Jan 10;42(2):774-89. Epub 2013 Oct 10.

Department of Cell & Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA, Program of Gene Expression and Regulation, The Wistar Institute, Philadelphia, PA 19104, USA, Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA and Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.

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http://dx.doi.org/10.1093/nar/gkt910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902912PMC
January 2014

EBNA1 binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells.

Virol J 2014 Jan 24;11:12. Epub 2014 Jan 24.

The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/1743-422X-11-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904692PMC
January 2014

Interpreting the Epstein-Barr Virus (EBV) epigenome using high-throughput data.

Viruses 2013 Apr 2;5(4):1042-54. Epub 2013 Apr 2.

Memorial Sloan Kettering Cancer Center, NY, USA.

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http://dx.doi.org/10.3390/v5041042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705264PMC
April 2013

EBV latency types adopt alternative chromatin conformations.

PLoS Pathog 2011 Jul 28;7(7):e1002180. Epub 2011 Jul 28.

The Wistar Institute, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145795PMC
July 2011

Biological effects of MC2050, a quinazoline-based PARP-1 inhibitor, in human neuroblastoma and EBV-positive Burkitt's lymphoma cells.

ChemMedChem 2011 Apr 1;6(4):606-11. Epub 2011 Mar 1.

Department of Biochemical Sciences, "Sapienza" University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

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http://dx.doi.org/10.1002/cmdc.201000536DOI Listing
April 2011

CTCF prevents the epigenetic drift of EBV latency promoter Qp.

PLoS Pathog 2010 Aug 12;6(8):e1001048. Epub 2010 Aug 12.

The Wistar Institute, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1001048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921154PMC
August 2010

Chromatin organization of gammaherpesvirus latent genomes.

Biochim Biophys Acta 2010 Mar-Apr;1799(3-4):236-45. Epub 2009 Oct 22.

The Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.bbagrm.2009.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839031PMC
May 2010

Regulation of Epstein-Barr virus OriP replication by poly(ADP-ribose) polymerase 1.

J Virol 2010 May 10;84(10):4988-97. Epub 2010 Mar 10.

The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1128/JVI.02333-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863838PMC
May 2010

GD3 nuclear localization after apoptosis induction in HUT-78 cells.

Biochem Biophys Res Commun 2008 Apr 7;368(3):495-500. Epub 2008 Feb 7.

Department of Biochemical Sciences, University "La Sapienza", p.le A. Moro, 5, 00185 Roma, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2007.12.196DOI Listing
April 2008

Characterization of catechol-thioether-induced apoptosis in human SH-SY5Y neuroblastoma cells.

J Neurosci Res 2008 Mar;86(4):954-60

Department of Biochemical Sciences, University Sapienza, Roma, Italy.

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http://dx.doi.org/10.1002/jnr.21536DOI Listing
March 2008

Inhibition of Poly(ADP-ribose)polymerase impairs Epstein Barr Virus lytic cycle progression.

Infect Agent Cancer 2007 Oct 11;2:18. Epub 2007 Oct 11.

Department of Biochemical Sciences, University "Sapienza", P,le Aldo Moro, 5, 00185, Rome, Italy.

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http://dx.doi.org/10.1186/1750-9378-2-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170434PMC
October 2007