Istvan Bartha

Istvan Bartha

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Istvan Bartha

Istvan Bartha

Publications by authors named "Istvan Bartha"

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Functional characterization of 3D protein structures informed by human genetic diversity.

Proc Natl Acad Sci U S A 2019 Apr 15;116(18):8960-8965. Epub 2019 Apr 15.

The Scripps Research Institute, La Jolla, CA 92037;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1820813116
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http://dx.doi.org/10.1073/pnas.1820813116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500140PMC
April 2019

Human gene essentiality.

Nat Rev Genet 2018 Jan 30;19(1):51-62. Epub 2017 Oct 30.

Human Longevity Inc., San Diego, California 92121, USA.

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http://dx.doi.org/10.1038/nrg.2017.75DOI Listing
January 2018

Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control.

PLoS Comput Biol 2017 02 9;13(2):e1005339. Epub 2017 Feb 9.

School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1371/journal.pcbi.1005339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300119PMC
February 2017

Corrigendum: Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Sepsis.

Front Immunol 2016 27;7:447. Epub 2016 Oct 27.

Lady Cilento Children's Hospital, Brisbane, QLD, Australia; Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Paediatric Critical Care Research Group (PCCRG), Mater Research, University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.3389/fimmu.2016.00447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081341PMC
October 2016

Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Sepsis.

Front Immunol 2016 20;7:357. Epub 2016 Sep 20.

Lady Cilento Children's Hospital, Brisbane, QLD, Australia; Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Paediatric Critical Care Research Group (PCCRG), Mater Research, University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.3389/fimmu.2016.00357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028722PMC
September 2016

Role of APOBEC3F Gene Variation in HIV-1 Disease Progression and Pneumocystis Pneumonia.

PLoS Genet 2016 Mar 4;12(3):e1005921. Epub 2016 Mar 4.

Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778847PMC
March 2016

Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses.

Am J Hum Genet 2015 Nov 8;97(5):738-43. Epub 2015 Oct 8.

School of Life Sciences, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.ajhg.2015.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667104PMC
November 2015

Adaptation on a genomic scale.

Elife 2015 Feb 3;4:e06193. Epub 2015 Feb 3.

School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland and Host-pathogen genomics group, Swiss Institute of Bioinformatics, Lausanne, Switzerland,

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http://dx.doi.org/10.7554/eLife.06193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337601PMC
February 2015

Analysis of stop-gain and frameshift variants in human innate immunity genes.

PLoS Comput Biol 2014 Jul 24;10(7):e1003757. Epub 2014 Jul 24.

Department of Laboratories, University Hospital of Lausanne, Lausanne, Switzerland; University of Lausanne, Lausanne, Switzerland.

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https://dx.plos.org/10.1371/journal.pcbi.1003757
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http://dx.doi.org/10.1371/journal.pcbi.1003757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110073PMC
July 2014

Dynamics of HIV latency and reactivation in a primary CD4+ T cell model.

PLoS Pathog 2014 May 29;10(5):e1004156. Epub 2014 May 29.

Institute of Microbiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1004156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038609PMC
May 2014

GuavaH: a compendium of host genomic data in HIV biology and disease.

Retrovirology 2014 Jan 15;11. Epub 2014 Jan 15.

Institute of Microbiology, University Hospital Lausanne, Lausanne, Switzerland.

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http://retrovirology.biomedcentral.com/articles/10.1186/1742
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http://dx.doi.org/10.1186/1742-4690-11-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937115PMC
January 2014

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.

Elife 2013 Oct 29;2:e01123. Epub 2013 Oct 29.

School of Life Sciences , École Polytechnique Fédérale de Lausanne , Lausanne , Switzerland ; Institute of Microbiology , University Hospital and University of Lausanne , Lausanne , Switzerland ; Research Group of Theoretical Biology and Evolutionary Ecology , Eötvös Loránd University and the Hungarian Academy of Sciences , Budapest , Hungary ; Swiss Institute of Bioinformatics , Lausanne , Switzerland.

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http://dx.doi.org/10.7554/eLife.01123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807812PMC
October 2013

Structural insights into the Trp-cage folding intermediate formation.

Chemistry 2013 Feb 14;19(8):2628-40. Epub 2013 Jan 14.

Laboratory of Structural Chemistry and Biology, Institute of Chemistry and Protein Modeling Group of HAS-ELTE, Eötvös Loránd University, 1117 Budapest, Pázmány Péter sétány 1/A, Hungary.

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http://dx.doi.org/10.1002/chem.201203764DOI Listing
February 2013

24 hours in the life of HIV-1 in a T cell line.

PLoS Pathog 2013 Jan 31;9(1):e1003161. Epub 2013 Jan 31.

Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1003161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561177PMC
January 2013

Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints.

Retrovirology 2011 Nov 1;8:87. Epub 2011 Nov 1.

Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland.

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http://retrovirology.biomedcentral.com/articles/10.1186/1742
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http://dx.doi.org/10.1186/1742-4690-8-87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229471PMC
November 2011

Has HIV evolved to induce immune pathogenesis?

Trends Immunol 2008 Jul 2;29(7):322-8. Epub 2008 Jun 2.

Institute of Biology, Eötvös Loránd University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.it.2008.04.005DOI Listing
July 2008