Publications by authors named "Issam S Hamadeh"

18 Publications

  • Page 1 of 1

Implications of Polymorphisms in the BCKDK and GATA-4 Gene Regions on Stable Warfarin Dose in African Americans.

Authors:
Salma A Bargal Jennifer N Kight Felipe Augusto de Oliveira Mohamed H Shahin Taimour Langaee Yan Gong Issam S Hamadeh Rhonda M Cooper-DeHoff Larisa H Cavallari

Clin Transl Sci 2020 Dec 5. Epub 2020 Dec 5.

Department of Pharmacotherapy & Translational Research, Center for Pharmacogenomics & Precision Medicine, College of Pharmacy, University of Florida, Gainesville, Florida, USA.

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December 2020

Phase 2 Study of the Safety and Efficacy of Umbralisib in Patients with CLL Who Are Intolerant to BTK or PI3Kδ Inhibitor Therapy.

Authors:
Anthony R Mato Nilanjan Ghosh Stephen J Schuster Nicole Lamanna John M Pagel Ian W Flinn Jacqueline Barrientos Kanti R Rai James A Reeves Bruce D Cheson Paul M Barr Suman Kambhampati Frederick Lansigan Jeffrey J Pu Alan P Skarbnik Lindsey Elizabeth Roeker Gustavo Fonseca Andrea Sitlinger Issam S Hamadeh Colleen Dorsey Nicole LaRatta Hanna Weissbrot Eline T Luning Prak Patricia Y Tsao Dana Paskalis Peter Sportelli Hari P Miskin Michael S Weiss Jakub Svoboda Danielle M Brander

Blood 2020 Dec 1. Epub 2020 Dec 1.

Duke University Health System, Durham, North Carolina, United States.

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December 2020

Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores.

Authors:
Cameron D Thomas Scott A Mosley Sarah Kim Karthik Lingineni Nihal El Rouby Taimour Y Langaee Yan Gong Danxin Wang Siegfried O Schmidt Philip F Binkley David S Estores Kairui Feng Hyewon Kim Minori Kinjo Zhichuan Li Lanyan Fang Arlene B Chapman Rhonda M Cooper-DeHoff John G Gums Issam S Hamadeh Liang Zhao Stephan Schmidt Reginald F Frye Julie A Johnson Larisa H Cavallari

CPT Pharmacometrics Syst Pharmacol 2020 Dec 3;9(12):678-685. Epub 2020 Nov 3.

Department of Pharmacotherapy and Translation Research, Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, Florida, USA.

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December 2020

Pharmacogenomics-guided opioid management.

Authors:
Jai N Patel Issam S Hamadeh

BMJ Support Palliat Care 2020 12 21;10(4):374-378. Epub 2020 Aug 21.

Department of Cancer Pharmacology & Pharmacogenomics, Levine Cancer Institute, Charlotte, North Carolina, USA.

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December 2020

Pharmacogenetics and tacrolimus administration in stem cell transplantation.

Authors:
Jai N Patel Issam S Hamadeh

Pharmacogenomics 2020 04 20;21(6):419-426. Epub 2020 Apr 20.

Department of Cancer Pharmacology, Levine Cancer Institute, Atrium Health, Charlotte, NC 28204, USA.

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April 2020

Safety and Cost Benefits of the Rapid Daratumumab Infusion Protocol.

Authors:
Issam S Hamadeh Emily S Reese Justin R Arnall Ekaterina Kachur Allison L Martin Meghan Schneider Reed Friend Barry Paul Shebli Atrash Manisha Bhutani Peter M Voorhees Saad Z Usmani

Clin Lymphoma Myeloma Leuk 2020 08 7;20(8):526-532.e1. Epub 2020 Mar 7.

Plasma Cell Disorders Division, Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute/Atrium Health, Charlotte, NC. Electronic address:

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August 2020

Pain Management Using Clinical Pharmacy Assessments With and Without Pharmacogenomics in an Oncology Palliative Medicine Clinic.

Authors:
Jai N Patel Danielle Boselli Issam S Hamadeh James Symanowski Rebecca Edwards Beth Susi Rebecca Greiner Donna Baldassare Melissa Waller Stephanie Wodarski ShRhonda Turner Courtney Slaughter Connie Edelen

JCO Oncol Pract 2020 02 7;16(2):e166-e174. Epub 2020 Jan 7.

Department of Supportive Oncology, Levine Cancer Institute, Atrium Health, Charlotte, NC.

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February 2020

Evaluation of CYP2C19 Genotype-Guided Voriconazole Prophylaxis After Allogeneic Hematopoietic Cell Transplant.

Authors:
Jai N Patel Issam S Hamadeh Myra Robinson Zainab Shahid James Symanowski Nury Steuerwald Alicia Hamilton Emily S Reese Dragos C Plesca Justin Arnall Margaret Taylor Jigar Trivedi Michael R Grunwald Jonathan Gerber Nilanjan Ghosh Belinda Avalos Edward Copelan

Clin Pharmacol Ther 2020 03 26;107(3):571-579. Epub 2019 Oct 26.

Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, North Carolina, USA.

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March 2020

Pharmacogenomics of osteonecrosis of the jaw.

Authors:
Guang Yang Sonal Singh Yiqing Chen Issam S Hamadeh Taimour Langaee Caitrin W McDonough L Shannon Holliday Jatinder K Lamba Jan S Moreb Joseph Katz Yan Gong

Bone 2019 07 22;124:75-82. Epub 2019 Apr 22.

Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL, USA; UF Health Cancer Center, Gainesville, FL, USA. Electronic address:

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July 2019

Effect of CYP3A4, CYP3A5, and ABCB1 Polymorphisms on Intravenous Tacrolimus Exposure and Adverse Events in Adult Allogeneic Stem Cell Transplant Patients.

Authors:
Issam S Hamadeh Qing Zhang Nury Steuerwald Alicia Hamilton Lawrence J Druhan Meredith McSwain Yordanis Diez Stephanie Rusin Yimei Han James Symanowski Jonathan Gerber Michael R Grunwald Nilanjan Ghosh Dragos Plesca Justin Arnall Jigar Trivedi Belinda Avalos Edward Copelan Jai N Patel

Biol Blood Marrow Transplant 2019 04 29;25(4):656-663. Epub 2018 Dec 29.

Department of Cancer Pharmacology, Levine Cancer Institute, Atrium Health, Charlotte, North Carolina. Electronic address:

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April 2019

Personalizing aromatase inhibitor therapy in patients with breast cancer.

Authors:
Issam S Hamadeh Jai N Patel Stephanie Rusin Antoinette R Tan

Cancer Treat Rev 2018 Nov 23;70:47-55. Epub 2018 Jul 23.

Department of Solid Tumor Oncology and Investigational Therapeutics, Levine Cancer Institute, Atrium Health, Charlotte, NC, United States.

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November 2018

Optimization of Voriconazole Therapy for the Treatment of Invasive Fungal Infections in Adults.

Authors:
Naveen Mangal Issam S Hamadeh Meghan J Arwood Larisa H Cavallari Tanay S Samant Kenneth P Klinker Jurgen Bulitta Stephan Schmidt

Clin Pharmacol Ther 2018 11 13;104(5):957-965. Epub 2018 Feb 13.

Center for Pharmacometrics & Systems Pharmacology, College of Pharmacy, University of Florida, Orlando, Florida, USA.

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November 2018

Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.

Authors:
Larisa H Cavallari Craig R Lee Amber L Beitelshees Rhonda M Cooper-DeHoff Julio D Duarte Deepak Voora Stephen E Kimmel Caitrin W McDonough Yan Gong Chintan V Dave Victoria M Pratt Tameka D Alestock R David Anderson Jorge Alsip Amer K Ardati Brigitta C Brott Lawrence Brown Supatat Chumnumwat Michael J Clare-Salzler James C Coons Joshua C Denny Chrisly Dillon Amanda R Elsey Issam S Hamadeh Shuko Harada William B Hillegass Lindsay Hines Richard B Horenstein Lucius A Howell Linda J B Jeng Mark D Kelemen Yee Ming Lee Oyunbileg Magvanjav May Montasser David R Nelson Edith A Nutescu Devon C Nwaba Ruth E Pakyz Kathleen Palmer Josh F Peterson Toni I Pollin Alison H Quinn Shawn W Robinson Jamie Schub Todd C Skaar D Max Smith Vindhya B Sriramoju Petr Starostik Tomasz P Stys James M Stevenson Nicholas Varunok Mark R Vesely Dyson T Wake Karen E Weck Kristin W Weitzel Russell A Wilke James Willig Richard Y Zhao Rolf P Kreutz George A Stouffer Philip E Empey Nita A Limdi Alan R Shuldiner Almut G Winterstein Julie A Johnson

JACC Cardiovasc Interv 2018 01 1;11(2):181-191. Epub 2017 Nov 1.

Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida; Department of Medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida.

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January 2018

SIRT1/HERC4 Locus Associated With Bisphosphonate-Induced Osteonecrosis of the Jaw: An Exome-Wide Association Analysis.

Authors:
Guang Yang Issam S Hamadeh Joseph Katz Alberto Riva Peter Lakatos Bernadett Balla Janos Kosa Mihaly Vaszilko Gian Andrea Pelliccioni Noa Davis Taimour Y Langaee Jan S Moreb Yan Gong

J Bone Miner Res 2018 01 16;33(1):91-98. Epub 2017 Oct 16.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL, USA.

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January 2018

Impact of the CYP2C19 genotype on voriconazole exposure in adults with invasive fungal infections.

Authors:
Issam S Hamadeh Kenneth P Klinker Samuel J Borgert Ashley I Richards Wenhui Li Naveen Mangal John W Hiemenz Stephan Schmidt Taimour Y Langaee Charles A Peloquin Julie A Johnson Larisa H Cavallari

Pharmacogenet Genomics 2017 05;27(5):190-196

aDepartment of Pharmacotherapy and Translational Research bCenter for Pharmacogenomics, College of Pharmacy, University of Florida cUniversity of Florida Health Shands Hospital, Gainesville dDepartment of Pharmaceutics eCenter for Pharmacometrics and Systems Pharmacology, College of Pharmacy, University of Florida, Orlando fDepartment of Medicine, Division of Hematology and Oncology gDepartment of Medicine, Division of Cardiology, College of Medicine, University of Florida, Gainesville, Florida, USA.

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May 2017

Osteonecrosis of the Jaw in the United States Food and Drug Administration's Adverse Event Reporting System (FAERS).

Authors:
Xiaoyan Zhang Issam S Hamadeh Shuang Song Joseph Katz Jan S Moreb Taimour Y Langaee Lawrence J Lesko Yan Gong

J Bone Miner Res 2016 Feb 4;31(2):336-40. Epub 2015 Sep 4.

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.

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February 2016

Drug induced osteonecrosis of the jaw.

Authors:
Issam S Hamadeh Bridget A Ngwa Yan Gong

Cancer Treat Rev 2015 May 21;41(5):455-64. Epub 2015 Apr 21.

Center for Pharmacogenomics, Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Fl, United States. Electronic address:

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May 2015

Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for tamoxifen pharmacogenetic studies.

Authors:
Julie A Johnson Issam S Hamadeh Taimour Y Langaee

J Natl Cancer Inst 2015 Feb 31;107(2). Epub 2015 Jan 31.

Center for Pharmacogenomics, Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL (JAJ, ISH, TYL).

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February 2015