Isaura Simoes

Isaura Simoes

UNVERIFIED PROFILE

Are you Isaura Simoes?   Register this Author

Register author
Isaura Simoes

Isaura Simoes

Publications by authors named "Isaura Simoes"

Are you Isaura Simoes?   Register this Author

21Publications

244Reads

24Profile Views

Macrophages Infected by a Pathogen and a Non-pathogen Spotted Fever Group Reveal Differential Reprogramming Signatures Early in Infection.

Front Cell Infect Microbiol 2019 10;9:97. Epub 2019 Apr 10.

Vector Borne Disease Laboratories, Department of Pathobiological Sciences, LSU School of Veterinary Medicine, Baton Rouge, LA, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcimb.2019.00097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467950PMC
December 2019

Use of recombinant proteins as a simple and robust normalization method for untargeted proteomics screening: exhaustive performance assessment.

Talanta 2019 Dec 18;205:120163. Epub 2019 Jul 18.

CNC, Center for Neuroscience and Cell Biology, University of Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.talanta.2019.120163DOI Listing
December 2019

A Pathogen and a Non-pathogen Spotted Fever Group Trigger Differential Proteome Signatures in Macrophages.

Front Cell Infect Microbiol 2019 6;9:43. Epub 2019 Mar 6.

Vector Borne Disease Laboratories, Department of Pathobiological Sciences, LSU School of Veterinary Medicine, Baton Rouge, LA, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcimb.2019.00043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414445PMC
November 2019

Atypical and nucellin-like aspartic proteases: emerging players in plant developmental processes and stress responses.

J Exp Bot 2019 Apr;70(7):2059-2076

Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jxb/erz034DOI Listing
April 2019

An atypical aspartic protease modulates lateral root development in Arabidopsis thaliana.

J Exp Bot 2019 Apr;70(7):2157-2171

Institute for Interdisciplinary Research, University of Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jxb/erz059DOI Listing
April 2019

Cardoon-based rennets for cheese production.

Appl Microbiol Biotechnol 2018 Jun 26;102(11):4675-4686. Epub 2018 Apr 26.

Biocant, Biotechnology Innovation Center, Parque Tecnológico de Cantanhede, Núcleo 4, Lote 8, 3060-197, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-018-9032-3DOI Listing
June 2018

Differences in Intracellular Fate of Two Spotted Fever Group Rickettsia in Macrophage-Like Cells.

Front Cell Infect Microbiol 2016 29;6:80. Epub 2016 Jul 29.

Vector Borne Disease Laboratories, Department of Pathobiological Sciences, LSU School of Veterinary Medicine Baton Rouge, LA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcimb.2016.00080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965480PMC
September 2017

Functional and structural characterization of synthetic cardosin B-derived rennet.

Appl Microbiol Biotechnol 2017 Sep 2;101(18):6951-6968. Epub 2017 Aug 2.

Biocant, Biotechnology Innovation Center, Parque Tecnológico de Cantanhede, Núcleo 4 Lote 8, 3060-197, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-017-8445-8DOI Listing
September 2017

Biophysical characterization of laforin-carbohydrate interaction.

Biochem J 2016 Feb 17;473(3):335-45. Epub 2015 Nov 17.

Biocant-Biotechnology Innovation Center, Parque Tecnológico de Cantanhede, Núcleo 4, Lote 8-3060-197 Cantanhede, Portugal

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20141555DOI Listing
February 2016

Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease.

Acta Crystallogr D Biol Crystallogr 2015 Oct 30;71(Pt 10):2109-18. Epub 2015 Sep 30.

Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, MD 21702, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S1399004715013905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601372PMC
October 2015

Engineering a cardosin B-derived rennet for sheep and goat cheese manufacture.

Appl Microbiol Biotechnol 2015 Jan 2;99(1):269-81. Epub 2014 Jul 2.

Biocant, Biotechnology Innovation Center, Parque Tecnológico de Cantanhede, Núcleo 4, Lote 3, 3060-197, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-014-5902-5DOI Listing
January 2015

RC1339/APRc from Rickettsia conorii is a novel aspartic protease with properties of retropepsin-like enzymes.

PLoS Pathog 2014 Aug 21;10(8):e1004324. Epub 2014 Aug 21.

The Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal; Biocant, Biotechnology Innovation Center, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1004324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140852PMC
August 2014

Effect of α-synuclein on amyloid β-induced toxicity: relevance to Lewy body variant of Alzheimer disease.

Neurochem Res 2013 Apr 7;38(4):797-806. Epub 2013 Feb 7.

Center for Neuroscience and Cell Biology, University of Coimbra, Largo Marquês de Pombal, 3004-517 Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11064-013-0982-7DOI Listing
April 2013

Molecular cloning and characterization of procirsin, an active aspartic protease precursor from Cirsium vulgare (Asteraceae).

Phytochemistry 2012 Sep 21;81:7-18. Epub 2012 Jun 21.

Laboratorio de Investigación de Proteínas Vegetales (LIPROVE), Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phytochem.2012.05.028DOI Listing
September 2012

Chlapsin, a chloroplastidial aspartic proteinase from the green algae Chlamydomonas reinhardtii.

Planta 2012 Jul 19;236(1):283-96. Epub 2012 Feb 19.

Biocant, Biotechnology Innovation Center, Molecular Biotechnology Unit, Parque Tecnológico de Cantanhede, Núcleo 4 Lote 3, 3060-197, Cantanhede, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00425-012-1605-2DOI Listing
July 2012

Shewasin A, an active pepsin homolog from the bacterium Shewanella amazonensis.

FEBS J 2011 Sep 11;278(17):3177-86. Epub 2011 Aug 11.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1742-4658.2011.08243.x
Publisher Site
http://dx.doi.org/10.1111/j.1742-4658.2011.08243.xDOI Listing
September 2011

Characterization of recombinant CDR1, an Arabidopsis aspartic proteinase involved in disease resistance.

J Biol Chem 2007 Oct 24;282(43):31358-65. Epub 2007 Jul 24.

Departamento de Biologia Molecular e Biotecnologia, Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Apt. 3126, Coimbra 3000, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M702477200DOI Listing
October 2007

Molecular analysis of the interaction between cardosin A and phospholipase D(alpha). Identification of RGD/KGE sequences as binding motifs for C2 domains.

FEBS J 2005 Nov;272(22):5786-98

Departamento de Biologia Molecular e Biotecnologia, Centro de Neurociências e Biologia Celular, Universidade de Coimbra and Departamento de Bioquímica, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1742-4658.2005.04967.xDOI Listing
November 2005

Structure and function of plant aspartic proteinases.

Eur J Biochem 2004 Jun;271(11):2067-75

Departamento de Biologia Molecular e Biotecnologia, Centro de Neurociências e Biologia Celular, Universidade de Coimbra, 3000 Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1432-1033.2004.04136.x
Publisher Site
http://dx.doi.org/10.1111/j.1432-1033.2004.04136.xDOI Listing
June 2004