Isao Tsuboi

Isao Tsuboi

UNVERIFIED PROFILE

Are you Isao Tsuboi?   Register this Author

Register author
Isao Tsuboi

Isao Tsuboi

Publications by authors named "Isao Tsuboi"

Are you Isao Tsuboi?   Register this Author

36Publications

383Reads

47Profile Views

Dynamics of hematopoiesis is disrupted by impaired hematopoietic microenvironment in a mouse model of hemophagocytic lymphohistiocytosis.

Ann Hematol 2020 Jul 6;99(7):1515-1523. Epub 2020 Jun 6.

Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine, 30-1 Ohyaguchi-kami-machi, Itabashi-ku, Tokyo, 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00277-020-04095-2DOI Listing
July 2020

Senescence-accelerated mice (SAMP1/TA-1) treated repeatedly with lipopolysaccharide develop a condition that resembles hemophagocytic lymphohistiocytosis.

Haematologica 2019 10 28;104(10):1995-2005. Epub 2019 Feb 28.

Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine, Tokyo.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2018.209551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886438PMC
October 2019

Combined treatment with benzo[a]pyrene and 1α,25-dihydroxyvitamin D induces expression of plasminogen activator inhibitor 1 in monocyte/macrophage-derived cells.

Toxicol Appl Pharmacol 2018 04 7;345:48-56. Epub 2018 Mar 7.

Division of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2018.03.003DOI Listing
April 2018

Long-Term Hypoxic Tolerance in Murine Cornea.

High Alt Med Biol 2018 03 20;19(1):35-41. Epub 2017 Dec 20.

1 Department of Functional Morphology, Nihon University School of Medicine , Itabashiku, Tokyo, Japan .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ham.2017.0114DOI Listing
March 2018

Differential Regulation of Lympho-Myelopoiesis by Stromal Cells in the Early and Late Phases in BALB/c Mice Repeatedly Exposed to Lipopolysaccharide.

Biol Pharm Bull 2016 ;39(12):1939-1947

Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1248/bpb.b16-00375DOI Listing
January 2017

A case of a quadricuspid pulmonary valve in a Japanese female.

Anat Sci Int 2016 Sep 24;91(4):419-22. Epub 2015 Oct 24.

Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12565-015-0310-1DOI Listing
September 2016

Quantitative Analysis of Formaldehyde-induced Fluorescence in Paraffin-embedded Specimens of Malignant Melanomas and Other Melanocytic Lesions.

Acta Derm Venereol 2016 Mar;96(3):309-13

Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2340/00015555-2238DOI Listing
March 2016

Cell cycle of primitive hematopoietic progenitors decelerated in senescent mice is reactively accelerated after 2-Gy whole-body irradiation.

Exp Biol Med (Maywood) 2016 Mar 6;241(5):485-92. Epub 2016 Jan 6.

Department of Functional Morphology, Nihon University School of Medicine, Tokyo 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1535370215625472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950487PMC
March 2016

Lipopolysaccharide reciprocally alters the stromal cell-regulated positive and negative balance between myelopoiesis and B lymphopoiesis in C57BL/6 mice.

Biol Pharm Bull 2014 ;37(12):1872-81

Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1248/bpb.b14-00279DOI Listing
August 2015

Decreased "ineffective erythropoiesis" preserves polycythemia in mice under long-term hypoxia.

Clin Exp Med 2015 May 13;15(2):179-88. Epub 2014 Jun 13.

Department of Functional Morphology, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10238-014-0286-5DOI Listing
May 2015

Experimentally induced, synergistic late effects of a single dose of radiation and aging: significance in LKS fraction as compared with mature blood cells.

J Appl Toxicol 2015 Mar 21;35(3):230-40. Epub 2014 Nov 21.

Cellular and Molecular Toxicology Division, National Center for Biological Safety and Research, National Institute of Health Sciences, 1-18-1 Kamiyohga, Setagayaku, Tokyo, 158-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jat.3088DOI Listing
March 2015

Age-related decline of mast cell regeneration in senescence-accelerated mice (SAMP1) after chemical myeloablation due to senescent stromal cell impairment.

Exp Biol Med (Maywood) 2012 Nov;237(11):1289-97

Department of Functional Morphology, Nihon University School of Medicine, Ohyaguchi-kami-machi, Itabashiku, Tokyo.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1258/ebm.2012.012158DOI Listing
November 2012

Asymmetric uptake of sepiapterin and 7,8-dihydrobiopterin as a gateway of the salvage pathway of tetrahydrobiopterin biosynthesis from the lumenal surface of rat endothelial cells.

Mol Genet Metab 2011 Nov 12;104(3):404-6. Epub 2011 Jun 12.

Department of Functional Morphology, Nihon University School of Medicine Itabashi, Tokyo, 173-8610, Japan.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S109671921100188
Publisher Site
http://dx.doi.org/10.1016/j.ymgme.2011.06.003DOI Listing
November 2011

Novel three-dimensional long-term bone marrow culture system using polymer particles with grafted epoxy-polymer-chains supports the proliferation and differentiation of hematopoietic stem cells.

Exp Biol Med (Maywood) 2011 Nov 20;236(11):1342-50. Epub 2011 Oct 20.

Department of Internal Medicine, Nihon University School of Medicine, 30-1 Oyaguchikamicho, Itabashi-ku, Tokyo 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1258/ebm.2011.011075DOI Listing
November 2011

Inflammatory biomarker, neopterin, predominantly enhances myelopoiesis, which suppresses erythropoiesis via activated stromal cells.

Immunobiology 2010 May 9;215(5):348-55. Epub 2009 Jul 9.

Department of Functional Morphology, Nihon University School of Medicine, 30-1 Ohyaguchi-kami-machi, Itabashiku, Tokyo 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.imbio.2009.05.004DOI Listing
May 2010

Comparison of murine gene expression profiles between spontaneous and radiation-induced myelogenous leukemias: stochastic and probabilistic expression variances in the former vs radiation-specific expression commonalities in the latter.

Exp Hematol 2009 Feb 13;37(2):195-205. Epub 2008 Dec 13.

Division of Cellular and Molecular Toxicology, National Center for Biological Safety and Research, National Institute of Health Sciences, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2008.10.006DOI Listing
February 2009

Role of hematopoietic microenvironment in prolonged impairment of B cell regeneration in age-related stromal-cell-impaired SAMP1 mouse: effects of a single dose of 5-fluorouracil.

J Appl Toxicol 2008 Aug;28(6):797-805

Department of Functional Morphology, Nihon University School of Medicine, 30-1 Ohyaguchikami-machi, Itabashiku, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jat.1341DOI Listing
August 2008

Membrane channel connexin 32 maintains Lin(-)/c-kit(+) hematopoietic progenitor cell compartment: analysis of the cell cycle.

J Membr Biol 2007 Jun 15;217(1-3):105-13. Epub 2007 Jul 15.

Division of Cellular and Molecular Toxicology, Center for Biological Safety and Research, National Institute of Health Sciences, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00232-007-9042-zDOI Listing
June 2007

Protective role of connexin 32 in steady-state hematopoiesis, regeneration state, and leukemogenesis.

Exp Biol Med (Maywood) 2007 May;232(5):700-12

Division of Cellular and Molecular Toxicology, Center for Biological Safety and Research, National Institute of Health Sciences, Tokyo, Japan.

View Article

Download full-text PDF

Source
May 2007

Thioredoxin overexpression in mice, model of attenuation of oxidative stress, prevents benzene-induced hemato-lymphoid toxicity and thymic lymphoma.

Exp Hematol 2006 Dec;34(12):1687-97

Division of Cellular and Molecular Toxicology, Biological Safety and Research Center, National Institute of Health Sciences, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0301472X0600492
Publisher Site
http://dx.doi.org/10.1016/j.exphem.2006.08.005DOI Listing
December 2006

L-arginine import via cationic amino acid transporter CAT1 is essential for both differentiation and proliferation of erythrocytes.

Blood 2006 Feb 6;107(4):1352-6. Epub 2005 Oct 6.

Department of Molecular Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamasaki, Noda, Chiba, 278-8510, Japan.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2005-08-31
Publisher Site
http://dx.doi.org/10.1182/blood-2005-08-3166DOI Listing
February 2006

Role of polyamines derived from arginine in differentiation and proliferation of human blood cells.

Biol Pharm Bull 2006 Feb;29(2):234-9

Department of Molecular Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamasaki, Noda, Chiba 278-8510, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1248/bpb.29.234DOI Listing
February 2006

Effects of neopterin on the hematopoietic microenvironment of senescence-accelerated mice (SAM).

Biol Pharm Bull 2006 Jan;29(1):43-8

Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1248/bpb.29.43DOI Listing
January 2006

Ineffective erythropoiesis in mutant mice with deficient pyruvate kinase activity.

Exp Hematol 2005 Nov;33(11):1292-8

Department of Anatomy, Nihon University School of Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2005.07.008DOI Listing
November 2005

Cyclic polylactate inhibited growth of cloned leukemic cells through reducing glycolytic enzyme activities.

Oncol Rep 2005 Aug;14(2):501-5

Department of Anatomy, Nihon University School of Medicine, 30-1 Ohyaguchi-kami-machi, Itabashi-ku, Tokyo 173-8610, Japan.

View Article

Download full-text PDF

Source
August 2005

Expression of organic cation transporter OCTN1 in hematopoietic cells during erythroid differentiation.

Exp Hematol 2004 Dec;32(12):1156-62

Department of Molecular Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamasaki, Noda, Chiba, Japan.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0301472X0400291
Publisher Site
http://dx.doi.org/10.1016/j.exphem.2004.08.009DOI Listing
December 2004

Senescent B lymphopoiesis is balanced in suppressive homeostasis: decrease in interleukin-7 and transforming growth factor-beta levels in stromal cells of senescence-accelerated mice.

Exp Biol Med (Maywood) 2004 Jun;229(6):494-502

Division of Cellular and Molecular Toxicology, National Institute of Health Sciences, Tokyo 158-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/153537020422900607DOI Listing
June 2004

Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells.

Toxicology 2004 Jan;195(1):19-29

Division of Cellular and Molecular Toxicology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagayaku, Tokyo 158-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2003.08.014DOI Listing
January 2004

Requirement of soluble factors produced by bone marrow stromal cells on the growth of novel established human myeloma cell line.

Int J Oncol 2003 Mar;22(3):631-7

Department of Internal Medicine, Nihon University School of Medicine, Tokyo 173-8610, Japan.

View Article

Download full-text PDF

Source
March 2003