Isao Kosugi

Isao Kosugi

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Isao Kosugi

Isao Kosugi

Publications by authors named "Isao Kosugi"

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The NanoSuit method: a novel histological approach for examining paraffin sections in a nondestructive manner by correlative light and electron microscopy.

Lab Invest 2020 Jan 29;100(1):161-173. Epub 2019 Aug 29.

Institute for NanoSuit Research, Preeminent Medical Photonics Education & Research Center, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1038/s41374-019-0309-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917571PMC
January 2020

CD248 and integrin alpha-8 are candidate markers for differentiating lung fibroblast subtypes.

BMC Pulm Med 2020 Jan 21;20(1):21. Epub 2020 Jan 21.

Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu City, Shizuoka, 431-3192, Japan.

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http://dx.doi.org/10.1186/s12890-020-1054-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975017PMC
January 2020

Sarcoid-like reaction and vitiligo occurring after nivolumab therapy in a patient with metastatic melanoma.

J Dermatol 2019 10 15;46(10):e359-e360. Epub 2019 Apr 15.

Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1111/1346-8138.14887DOI Listing
October 2019

An Autopsy Case of a 5-Year-Old Child with Acute Pancreatitis Caused by Eosinophilic Granulomatosis with Polyangiitis-like Necrotizing Vasculitis.

Case Rep Rheumatol 2019 2;2019:9053747. Epub 2019 Sep 2.

Department of Diagnostic Pathology, Seirei Mikatahara Hospital, 3453 Mikataharacho, Hamamatsu 433-8558, Japan.

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http://dx.doi.org/10.1155/2019/9053747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745468PMC
September 2019

Infection of endotheliotropic human cytomegalovirus of trabecular meshwork cells.

Jpn J Ophthalmol 2018 Nov 6;62(6):667-676. Epub 2018 Sep 6.

Department of Ophthalmology and Visual Science, Tottori University Faculty of Medicine, 36-1 Nishicho, Yonago, 683-8504, Japan.

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http://link.springer.com/10.1007/s10384-018-0618-1
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http://dx.doi.org/10.1007/s10384-018-0618-1DOI Listing
November 2018

Podoplanin-positive myofibroblasts: a pathological hallmark of pleuroparenchymal fibroelastosis.

Histopathology 2018 Jun 25;72(7):1209-1215. Epub 2018 Mar 25.

Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine, Shizuoka, Japan.

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http://dx.doi.org/10.1111/his.13494DOI Listing
June 2018

A case of a primary hepatic so-called adenosarcoma with heterotopic ossification: possibly of biliary adenofibroma origin.

Hum Pathol 2018 03 24;73:108-113. Epub 2017 Oct 24.

Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, 431-3192, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00468177173037
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http://dx.doi.org/10.1016/j.humpath.2017.10.009DOI Listing
March 2018

MHC class I in dopaminergic neurons suppresses relapse to reward seeking.

Sci Adv 2018 03 14;4(3):eaap7388. Epub 2018 Mar 14.

Department of Psychology and Behavioral Neuroscience, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan.

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http://dx.doi.org/10.1126/sciadv.aap7388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851664PMC
March 2018

Digoxin Attenuates Murine Experimental Colitis by Downregulating Th17-related Cytokines.

Inflamm Bowel Dis 2017 05;23(5):728-738

*First Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan; Departments of †Health Science, ‡Infectious Diseases, §Regenerative and infectious Pathology, and ‖Endoscopic and Photodynamic Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan; and ¶Center for Clinical Research, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1097/MIB.0000000000001096DOI Listing
May 2017

Phenotypic characterization of perivascular myoid cell neoplasms, using myosin 1B, a newly identified human pericyte marker.

Hum Pathol 2017 Apr 11;62:187-198. Epub 2017 Jan 11.

Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka 431-3192, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2016.12.024DOI Listing
April 2017

Pathogenesis of developmental anomalies of the central nervous system induced by congenital cytomegalovirus infection.

Pathol Int 2017 Feb 10;67(2):72-82. Epub 2017 Jan 10.

Department of Regenerative & Infectious Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1111/pin.12502DOI Listing
February 2017

H11/HSPB8 Restricts HIV-2 Vpx to Restore the Anti-Viral Activity of SAMHD1.

Front Microbiol 2016 13;7:883. Epub 2016 Jun 13.

Department of Microbiology, School of Medicine, Yokohama City University Yokohama, Japan.

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http://dx.doi.org/10.3389/fmicb.2016.00883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904303PMC
July 2016

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain.

J Vis Exp 2016 07 24(113). Epub 2016 Jul 24.

Department of Regenerative & Infectious Pathology, Hamamatsu University School of Medicine.

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http://dx.doi.org/10.3791/54164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091671PMC
July 2016

Restricted infection of murine cytomegalovirus (MCMV) in neonatal mice with MCMV-induced sensorineural hearing loss.

J Clin Virol 2015 Aug 19;69:138-45. Epub 2015 Jun 19.

Department of Microbiology, Fukushima Medical University School of Medicine, Fukushima, Japan.

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http://dx.doi.org/10.1016/j.jcv.2015.06.083DOI Listing
August 2015

Cytomegalovirus initiates infection selectively from high-level β1 integrin-expressing cells in the brain.

Am J Pathol 2015 May 19;185(5):1304-23. Epub 2015 Mar 19.

Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1016/j.ajpath.2015.01.032DOI Listing
May 2015

Aberrant fetal macrophage/microglial reactions to cytomegalovirus infection.

Ann Clin Transl Neurol 2014 Aug 28;1(8):570-88. Epub 2014 Jul 28.

Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine Hamamatsu, Japan.

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http://dx.doi.org/10.1002/acn3.88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184560PMC
August 2014

Direct isolation of myofibroblasts and fibroblasts from bleomycin-injured lungs reveals their functional similarities and differences.

Fibrogenesis Tissue Repair 2013 Aug 8;6(1):15. Epub 2013 Aug 8.

Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-ku, Hamamatsu, Japan.

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http://dx.doi.org/10.1186/1755-1536-6-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751789PMC
August 2013

Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin.

Mol Cell Biol 2012 Aug 29;32(15):2966-78. Epub 2012 May 29.

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://mcb.asm.org/content/early/2012/05/22/MCB.05688-11.ful
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http://mcb.asm.org/content/32/15/2966.full.pdf
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http://mcb.asm.org/cgi/doi/10.1128/MCB.05688-11
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http://dx.doi.org/10.1128/MCB.05688-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434519PMC
August 2012

[A case of malignant tumor of the ascending part of duodenum with osteoclast-like giant cells].

Nihon Shokakibyo Gakkai Zasshi 2011 Oct;108(10):1705-11

Department of Gastroenterology, Nagoya City West Medical Center.

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October 2011

Mouse embryonic stem cells inhibit murine cytomegalovirus infection through a multi-step process.

PLoS One 2011 Mar 2;6(3):e17492. Epub 2011 Mar 2.

Department of Second Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017492PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047572PMC
March 2011

[Cytomegalovirus (CMV)].

Authors:
Isao Kosugi

Uirusu 2010 Dec;60(2):209-20

Department of Pathology II, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.

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http://dx.doi.org/10.2222/jsv.60.209DOI Listing
December 2010

In vivo imaging assay for the convenient evaluation of antiviral compounds against cytomegalovirus in mice.

Antiviral Res 2010 Oct 13;88(1):45-52. Epub 2010 Jul 13.

Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.antiviral.2010.07.002DOI Listing
October 2010

Aggressive progression of breast cancer with microscopic pulmonary emboli possessing a stem cell-like phenotype independent of its origin.

Pathol Int 2010 Mar;60(3):228-34

Department of Second Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan.

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http://dx.doi.org/10.1111/j.1440-1827.2009.02502.xDOI Listing
March 2010

Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.

J Biol Chem 2009 Oct 13;284(41):27766-79. Epub 2009 Aug 13.

Department of Biochemistry 1, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka 431-3192, Japan.

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http://dx.doi.org/10.1074/jbc.M109.006809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788827PMC
October 2009

Induction of cytomegalovirus-infected labyrinthitis in newborn mice by lipopolysaccharide: a model for hearing loss in congenital CMV infection.

Lab Invest 2008 Jul 12;88(7):722-30. Epub 2008 May 12.

Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1038/labinvest.2008.39DOI Listing
July 2008

Roles of neural stem progenitor cells in cytomegalovirus infection of the brain in mouse models.

Pathol Int 2008 May;58(5):257-67

Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1111/j.1440-1827.2008.02221.xDOI Listing
May 2008

Enhancement of susceptibility of adult mouse brain to cytomegalovirus infection by infusion of epidermal growth factor.

J Neurosci Res 2007 Oct;85(13):2981-90

Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1002/jnr.21410DOI Listing
October 2007

Cyclosporine inhibits mouse cytomegalovirus infection via a cyclophilin-dependent pathway specifically in neural stem/progenitor cells.

J Virol 2007 Sep 6;81(17):9013-23. Epub 2007 Jun 6.

Department of Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.00261-07
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http://dx.doi.org/10.1128/JVI.00261-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951393PMC
September 2007

[Neuropathogenesis in cytomegalovirus infection].

Tanpakushitsu Kakusan Koso 2007 Aug;52(10 Suppl):1254-60

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August 2007

Mouse embryonic stem cells are not susceptible to cytomegalovirus but acquire susceptibility during differentiation.

Birth Defects Res A Clin Mol Teratol 2006 Feb;76(2):115-25

Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1002/bdra.20233DOI Listing
February 2006

Neuropathogenesis in cytomegalovirus infection: indication of the mechanisms using mouse models.

Rev Med Virol 2005 Sep-Oct;15(5):327-45

Department of Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Japan.

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http://dx.doi.org/10.1002/rmv.475DOI Listing
October 2005

Cytomegalovirus infection inhibits the expression of N-methyl-D-aspartate receptors in the developing mouse hippocampus and primary neuronal cultures.

Acta Neuropathol 2005 May 10;109(5):475-82. Epub 2005 Mar 10.

Department of Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192, Hamamatsu, Japan.

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http://dx.doi.org/10.1007/s00401-005-0987-7DOI Listing
May 2005

Activation of murine cytomegalovirus immediate-early promoter in mouse brain after transplantation of the neural stem cells.

Acta Neuropathol 2004 May 23;107(5):406-12. Epub 2004 Mar 23.

Second Department of Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, 431-3192 Hamamatsu, Japan.

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http://dx.doi.org/10.1007/s00401-004-0828-0DOI Listing
May 2004

Traumatic basal subarachnoid haemorrhage caused by the impact of a golf ball: a case report.

Med Sci Law 2003 Apr;43(2):174-8

Department of Legal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Japan.

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http://dx.doi.org/10.1258/rsmmsl.43.2.174DOI Listing
April 2003

The amount of immature glial cells in organotypic brain slices determines the susceptibility to murine cytomegalovirus infection.

Lab Invest 2002 Oct;82(10):1347-58

Second Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1097/01.lab.0000032376.58688.d4DOI Listing
October 2002

Reactivation of latent cytomegalovirus infection in mouse brain cells detected after transfer to brain slice cultures.

J Virol 2002 Jul;76(14):7247-54

Second Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136329PMC
http://dx.doi.org/10.1128/jvi.76.14.7247-7254.2002DOI Listing
July 2002

Giant inflammatory polyposis of the descending colon associated with a Crohn's disease-like colitis.

Pathol Int 2002 Apr;52(4):318-21

Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

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http://dx.doi.org/10.1046/j.1440-1827.2002.01348.xDOI Listing
April 2002