Publications by authors named "Isaiah J Fidler"

100Publications

Commentary on "Tumor Heterogeneity and the Biology of Cancer Invasion and Metastasis".

Authors:
Isaiah J Fidler

Cancer Res 2016 06;76(12):3441-2

University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1330DOI Listing
June 2016

Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel.

Neuro Oncol 2016 Apr;18(4):486-96

Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).

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http://dx.doi.org/10.1093/neuonc/now037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799693PMC
April 2016

The challenge of targeting metastasis.

Cancer Metastasis Rev 2015 Dec;34(4):635-41

Department of Immunology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 173, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s10555-015-9586-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661188PMC
December 2015

The Biology of Brain Metastasis: Challenges for Therapy.

Authors:
Isaiah J Fidler

Cancer J 2015 Jul-Aug;21(4):284-93

From the Cancer Metastasis Lab, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PPO.0000000000000126DOI Listing
May 2016

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs.

Authors:
Ayalew Tefferi Hagop Kantarjian S Vincent Rajkumar Lawrence H Baker Jan L Abkowitz John W Adamson Ranjana Hira Advani James Allison Karen H Antman Robert C Bast John M Bennett Edward J Benz Nancy Berliner Joseph Bertino Ravi Bhatia Smita Bhatia Deepa Bhojwani Charles D Blanke Clara D Bloomfield Linda Bosserman Hal E Broxmeyer John C Byrd Fernando Cabanillas George Peter Canellos Bruce A Chabner Asher Chanan-Khan Bruce Cheson Bayard Clarkson Susan L Cohn Gerardo Colon-Otero Jorge Cortes Steven Coutre Massimo Cristofanilli Walter J Curran George Q Daley Daniel J DeAngelo H Joachim Deeg Lawrence H Einhorn Harry P Erba Francisco J Esteva Elihu Estey Isaiah J Fidler James Foran Stephen Forman Emil Freireich Charles Fuchs James N George Morie A Gertz Sergio Giralt Harvey Golomb Peter Greenberg Jordan Gutterman Robert I Handin Samuel Hellman Paulo Marcelo Hoff Ronald Hoffman Waun Ki Hong Mary Horowitz Gabriel N Hortobagyi Clifford Hudis Jean Pierre Issa Bruce Evan Johnson Philip W Kantoff Kenneth Kaushansky David Khayat Fadlo R Khuri Thomas J Kipps Margaret Kripke Robert A Kyle Richard A Larson Theodore S Lawrence Ross Levine Michael P Link Scott M Lippman Sagar Lonial Gary H Lyman Maurie Markman John Mendelsohn Neal J Meropol Yoav Messinger Therese M Mulvey Susan O'Brien Roman Perez-Soler Raphael Pollock Josef Prchal Oliver Press Jerald Radich Kanti Rai Saul A Rosenberg Jacob M Rowe Hope Rugo Carolyn D Runowicz Brenda M Sandmaier Alan Saven Andrew I Schafer Charles Schiffer Mikkael A Sekeres Richard T Silver Lillian L Siu David P Steensma F Marc Stewart Wendy Stock Richard Stone Rainer Storb Louise C Strong Martin S Tallman Michael Thompson Naoto T Ueno Richard A Van Etten Julie M Vose Peter H Wiernik Eric P Winer Anas Younes Andrew D Zelenetz Charles A LeMaistre

Mayo Clin Proc 2015 Aug 23;90(8):996-1000. Epub 2015 Jul 23.

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http://dx.doi.org/10.1016/j.mayocp.2015.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365030PMC
August 2015

Modulation of the cancer cell transcriptome by culture media formulations and cell density.

Int J Oncol 2015 May 17;46(5):2067-75. Epub 2015 Mar 17.

Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.3892/ijo.2015.2930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383016PMC
May 2015

The molecular biology of lung cancer brain metastasis: an overview of current comprehensions and future perspectives.

J Med Invest 2014 ;61(3-4):241-53

Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, The University of Tokushima Graduate School.

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http://dx.doi.org/10.2152/jmi.61.241DOI Listing
May 2016

Hematogenous metastasis of ovarian cancer: rethinking mode of spread.

Cancer Cell 2014 Jul;26(1):77-91

Department of Gynecologic Oncology and Reproductive Medicine, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-coding RNA, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100212PMC
July 2014

Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells.

Neuro Oncol 2014 Dec 9;16(12):1585-98. Epub 2014 Jul 9.

Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (S.W.K., H.J.C., H.-J.L., J.H., Q.W., R.R.L., I.J.F., S.-J.K.).

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http://dx.doi.org/10.1093/neuonc/nou128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232084PMC
December 2014

Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresis.

Am J Transl Res 2013 24;5(4):441-9. Epub 2013 May 24.

Center for Molecular Medicine, China Medical University Hospital Taichung 404, Taiwan ; Graduate Institute of Cancer Biology, China Medical University Taichung 404, Taiwan ; the Ph.D. program for Cancer Biology and Drug Discovery, China Medical University Taichung 404, Taiwan ; Department of Biotechnology, Asia University Taichung 413, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665917PMC
June 2013

The biology of brain metastasis.

Clin Chem 2013 Jan 31;59(1):180-9. Epub 2012 Oct 31.

Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1373/clinchem.2012.193342DOI Listing
January 2013

Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers.

Cancer Lett 2013 Jul 18;334(2):319-27. Epub 2012 Sep 18.

Department of Nanomedicine, The Methodist Hospital Research Institute, 6670 Bertner St., Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.canlet.2012.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779123PMC
July 2013

Biological heterogeneity of cancer: implication to therapy.

Authors:
Isaiah J Fidler

Hum Vaccin Immunother 2012 Aug 1;8(8):1141-2. Epub 2012 Aug 1.

Department of Cancer Biology, Metastasis Research Center, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.4161/hv.19643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551889PMC
August 2012

Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist.

Transl Oncol 2012 Feb 1;5(1):39-47. Epub 2012 Feb 1.

Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281406PMC
http://dx.doi.org/10.1593/tlo.11286DOI Listing
February 2012

Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis.

Proc Natl Acad Sci U S A 2011 Oct 10;108(42):17456-61. Epub 2011 Oct 10.

Department of Systems Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1073/pnas.1114210108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198333PMC
October 2011

Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar.

Am J Pathol 2011 May;178(5):2357-66

Department of Cancer Biology-Cancer Metastasis Research Center, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1016/j.ajpath.2011.01.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081177PMC
May 2011

Identification and validation of SRC and phospho-SRC family proteins in circulating mononuclear cells as novel biomarkers for pancreatic cancer.

Transl Oncol 2011 Apr 1;4(2):83-91. Epub 2011 Apr 1.

Department of Cancer Biology, Cancer Metastasis Research Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069651PMC
http://dx.doi.org/10.1593/tlo.10202DOI Listing
April 2011

The seed and soil hypothesis revisited--the role of tumor-stroma interactions in metastasis to different organs.

Int J Cancer 2011 Jun 25;128(11):2527-35. Epub 2011 Mar 25.

Department of Cancer Biology, Cancer Metastasis Research Center, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/ijc.26031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075088PMC
June 2011

Formation of solid tumors by a single multinucleated cancer cell.

Cancer 2011 Sep 1;117(17):4092-9. Epub 2011 Mar 1.

Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, College of Natural Science and Mathematics, University of Houston, Houston, Texas, USA.

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http://dx.doi.org/10.1002/cncr.26021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136613PMC
September 2011

Consistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouse.

Int Immunopharmacol 2011 Jul 18;11(7):862-72. Epub 2011 Jan 18.

Department of Cancer Biology, Cancer Metastasis Research Center, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.intimp.2011.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086935PMC
July 2011

The role of the organ microenvironment in brain metastasis.

Authors:
Isaiah J Fidler

Semin Cancer Biol 2011 Apr 16;21(2):107-12. Epub 2010 Dec 16.

Department of Cancer Biology, Cancer Metastasis Research Center, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.semcancer.2010.12.009DOI Listing
April 2011

Nitric oxide-mediated tumoricidal activity of murine microglial cells.

Transl Oncol 2010 Dec 1;3(6):380-8. Epub 2010 Dec 1.

Department of Cancer Biology, Cancer Metastasis Research Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000463PMC
http://dx.doi.org/10.1593/tlo.10208DOI Listing
December 2010

The biology of cancer metastasis.

Authors:
Isaiah J Fidler

Semin Cancer Biol 2011 Apr 9;21(2):71. Epub 2010 Dec 9.

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http://dx.doi.org/10.1016/j.semcancer.2010.12.004DOI Listing
April 2011

Finding the tumor copycat. Therapy fails, patients don't.

Nat Med 2010 Sep;16(9):974-5

Department of Cancer Biology, Houston, Texas, USA.

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http://dx.doi.org/10.1038/nm0910-974DOI Listing
September 2010

The brain microenvironment and cancer metastasis.

Mol Cells 2010 Aug 19;30(2):93-8. Epub 2010 Aug 19.

Department of Cancer Biology, Cancer Metastasis Research Center, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

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http://link.springer.com/10.1007/s10059-010-0133-9
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http://dx.doi.org/10.1007/s10059-010-0133-9DOI Listing
August 2010

AACR centennial series: the biology of cancer metastasis: historical perspective.

Cancer Res 2010 Jul 7;70(14):5649-69. Epub 2010 Jul 7.

The University of Nebraska Medical Center, Transplantation Immunology Laboratory, Omaha, Nebraska, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037932PMC
July 2010

Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma.

Neoplasia 2010 Feb;12(2):173-82

Department of Surgical and Radiological Sciences, University of California Davis School of Medicine, Davis, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814355PMC
http://dx.doi.org/10.1593/neo.91604DOI Listing
February 2010

Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis.

Int J Oncol 2009 Oct;35(4):665-72

Department of Cancer Biology, Unit 173, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882684PMC
http://dx.doi.org/10.3892/ijo_00000378DOI Listing
October 2009

Circulating monocytes expressing CD31: implications for acute and chronic angiogenesis.

Am J Pathol 2009 May 6;174(5):1972-80. Epub 2009 Apr 6.

Department of Cancer Biology, Cancer MetastasisResearch Center, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.2353/ajpath.2009.080819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671284PMC
May 2009

Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain.

Cancer Res 2009 Feb 13;69(3):828-35. Epub 2009 Jan 13.

Department of Cancer Biology, Cancer Metastasis Research Center, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230-1429, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633423PMC
February 2009

Neoadjuvant platelet derived growth factor receptor inhibitor therapy combined with docetaxel and androgen ablation for high risk localized prostate cancer.

J Urol 2009 Jan 13;181(1):81-7; discussion 87. Epub 2008 Nov 13.

Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1016/j.juro.2008.09.006DOI Listing
January 2009

The "seed and soil" hypothesis revisited.

Lancet Oncol 2008 Aug;9(8):808

Cancer Metastasis Research Center, MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/S1470-2045(08)70201-8DOI Listing
August 2008

Survival of cancer cells is maintained by EGFR independent of its kinase activity.

Cancer Cell 2008 May;13(5):385-93

Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15356108080012
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http://dx.doi.org/10.1016/j.ccr.2008.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413063PMC
May 2008

Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy.

Clin Exp Metastasis 2008 7;25(4):477-89. Epub 2008 Mar 7.

Department of Cancer Biology, Unit 173, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10585-008-9153-7DOI Listing
August 2008

Impact of sentinel lymphadenectomy on survival in a murine model of melanoma.

Clin Exp Metastasis 2008 9;25(3):191-9. Epub 2008 Feb 9.

Department of Cancer Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10585-008-9141-yDOI Listing
July 2008

Stromal metalloproteinase-9 is essential to angiogenesis and progressive growth of orthotopic human pancreatic cancer in parabiont nude mice.

Neoplasia 2007 Nov;9(11):979-86

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77230-1429, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077889PMC
http://dx.doi.org/10.1593/neo.07742DOI Listing
November 2007

Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice.

Mol Cancer Ther 2007 Oct 3;6(10):2652-63. Epub 2007 Oct 3.

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 432, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0759DOI Listing
October 2007

Zonal heterogeneity for gene expression in human pancreatic carcinoma.

Cancer Res 2007 Aug;67(16):7597-604

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77230-1429, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-0874DOI Listing
August 2007

Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis.

Endocr Rev 2007 May 4;28(3):297-321. Epub 2007 Apr 4.

Department of Cancer Biology, Unit 173, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1210/er.2006-0027DOI Listing
May 2007

Murine models to evaluate novel and conventional therapeutic strategies for cancer.

Am J Pathol 2007 Mar;170(3):793-804

University of Nebraska Medical Center, 987660 Nebraska Medical Center, Omaha, NE 68198-7660, USA.

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http://dx.doi.org/10.2353/ajpath.2007.060929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1864878PMC
March 2007

Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade.

Mol Cancer Ther 2007 Feb;6(2):471-83

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Unit 97, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0416DOI Listing
February 2007

Gene expression profile of metastatic human pancreatic cancer cells depends on the organ microenvironment.

Cancer Res 2007 Jan;67(1):139-48

Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77230, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-06-2563DOI Listing
January 2007

The role of the organ microenvironment in the biology and therapy of cancer metastasis.

J Cell Biochem 2007 Jul;101(4):927-36

Department of Cancer Biology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/jcb.21148DOI Listing
July 2007

Models for spontaneous metastasis.

Authors:
Isaiah J Fidler

Cancer Res 2006 Oct;66(19):9787

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http://dx.doi.org/10.1158/0008-5472.CAN-06-2396DOI Listing
October 2006

Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential.

Int J Cancer 2006 Dec;119(11):2567-74

Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230-1429, USA.

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http://dx.doi.org/10.1002/ijc.22229DOI Listing
December 2006

Antivascular therapy of cancer metastasis.

Authors:
Isaiah J Fidler

J Surg Oncol 2006 Sep;94(3):178-80

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http://dx.doi.org/10.1002/jso.20380DOI Listing
September 2006

Loss of adhesion in the circulation converts amelanotic metastatic melanoma cells to melanotic by inhibition of AKT.

Neoplasia 2006 Jul;8(7):543-50

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1593/neo.05655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1601939PMC
July 2006

Apoptotic cells initiate endothelial cell sprouting via electrostatic signaling.

Cancer Res 2005 Dec;65(24):11529-35

Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, 77230, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1404497PMC
December 2005

Construction of a novel constitutively active chimeric EGFR to identify new targets for therapy.

Neoplasia 2005 Dec;7(12):1065-72

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501175PMC
http://dx.doi.org/10.1593/neo.05553DOI Listing
December 2005

Blockade of the TGF-beta superfamily by Smad7: breaking a link in the metastatic chain.

Authors:
Isaiah J Fidler

J Natl Cancer Inst 2005 Dec;97(23):1714-5

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http://dx.doi.org/10.1093/jnci/dji437DOI Listing
December 2005

Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine.

Cancer Res 2005 Dec;65(23):10794-800

Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77230-1429, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534114PMC
December 2005

Understanding bone metastases: the key to the effective treatment of prostate cancer.

Authors:
Isaiah J Fidler

Clin Adv Hematol Oncol 2003 May;1(5):278-9

Department of Cancer Biology, University of Texas M. D. Cancer Center, Houston, USA.

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May 2003

Cancer biology is the foundation for therapy.

Authors:
Isaiah J Fidler

Cancer Biol Ther 2005 Sep 7;4(9):1036-9. Epub 2005 Sep 7.

Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas 7703, USA.

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http://dx.doi.org/10.4161/cbt.4.9.2111DOI Listing
September 2005

Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer.

Int J Oncol 2005 Nov;27(5):1361-9

Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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November 2005

Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors.

Clin Cancer Res 2005 Jul;11(13):4923-33

Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77230-1439, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-2060DOI Listing
July 2005

Plasma protein profiling for diagnosis of pancreatic cancer reveals the presence of host response proteins.

Clin Cancer Res 2005 Feb;11(3):1110-8

Department of Molecular Pathology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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February 2005

Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells.

Clin Cancer Res 2005 Jan;11(2 Pt 1):440-9

Department of Surgical Oncology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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January 2005

Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice.

Clin Cancer Res 2005 Jan;11(1):306-14

Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas, USA.

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January 2005

Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage.

Prostate 2005 Jun;64(1):40-9

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://doi.wiley.com/10.1002/pros.20223
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http://dx.doi.org/10.1002/pros.20223DOI Listing
June 2005

From here to there; a life based on migration. An interview with Isaiah J. Fidler.

Authors:
Isaiah J Fidler

Int J Dev Biol 2004 ;48(5-6):457-62

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http://dx.doi.org/10.1387/ijdb.041790ihDOI Listing
February 2005

Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer.

J Clin Oncol 2004 Aug;22(16):3323-9

Department of Genitourinary Medical Oncology, Unit 427, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://ascopubs.org/doi/10.1200/JCO.2004.10.116
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http://dx.doi.org/10.1200/JCO.2004.10.116DOI Listing
August 2004

Neoplastic angiogenesis--not all blood vessels are created equal.

N Engl J Med 2004 Jul;351(3):215-6

Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, USA

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http://dx.doi.org/10.1056/NEJMp048080DOI Listing
July 2004

Combination docetaxel and platelet-derived growth factor receptor inhibition with imatinib mesylate in prostate cancer.

Semin Oncol 2004 Apr;31(2 Suppl 6):24-9

University of Texas M.D. Anderson Cancer Center, Department of Genitourinary Medical Oncology, Houston, 77030, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2004.03.037DOI Listing
April 2004

Activation of the platelet-derived growth factor-receptor enhances survival of murine bone endothelial cells.

Cancer Res 2004 Jun;64(11):3727-30

Department of Cancer Biology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-03-3863DOI Listing
June 2004

Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.

Clin Cancer Res 2004 Apr;10(7):2299-306

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.ccr-03-0488DOI Listing
April 2004

Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines.

Gynecol Oncol 2004 Apr;93(1):78-86

Department of Gynecologic Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.ygyno.2003.12.041DOI Listing
April 2004

Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma.

Clin Cancer Res 2004 Feb;10(3):897-908

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.ccr-1151-3DOI Listing
February 2004

Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model.

Clin Cancer Res 2003 Dec;9(17):6534-44

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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December 2003

Bioassay using epidermal keratinocytes to determine phosphorylation status of the epidermal growth factor receptor in distant neoplasms.

Int J Oncol 2004 Jan;24(1):19-24

Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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January 2004