Isabelle Lucet

Isabelle Lucet

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Isabelle Lucet

Isabelle Lucet

Publications by authors named "Isabelle Lucet"

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Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum.

Sci Rep 2019 Nov 13;9(1):16720. Epub 2019 Nov 13.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, 4051, Basel, Switzerland.

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http://dx.doi.org/10.1038/s41598-019-53325-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853920PMC
November 2019

The PEAK family of pseudokinases, their role in cell signalling and cancer.

FEBS J 2019 Oct 9. Epub 2019 Oct 9.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

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http://dx.doi.org/10.1111/febs.15087DOI Listing
October 2019

Eph receptor signalling: from catalytic to non-catalytic functions.

Oncogene 2019 09 12;38(39):6567-6584. Epub 2019 Aug 12.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1038/s41388-019-0931-2DOI Listing
September 2019

Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3.

Cell Rep 2019 Sep;28(13):3309-3319.e5

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.055DOI Listing
September 2019

FSHD2- and BAMS-associated mutations confer opposing effects on SMCHD1 function.

J Biol Chem 2018 06 10;293(25):9841-9853. Epub 2018 May 10.

From the Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia,

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http://dx.doi.org/10.1074/jbc.RA118.003104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016475PMC
June 2018

Characterization of Ligand Binding to Pseudokinases Using a Thermal Shift Assay.

Methods Mol Biol 2017 ;1636:91-104

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7154-1_7DOI Listing
April 2018

Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases.

J Biol Chem 2016 Oct 16;291(41):21571-21583. Epub 2016 Aug 16.

From the Cancer Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Level 1, Building 77, Monash University, Clayton, Victoria 3800,

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http://dx.doi.org/10.1074/jbc.M116.748897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076828PMC
October 2016

Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1.

Structure 2016 09 18;24(9):1550-61. Epub 2016 Aug 18.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.07.008DOI Listing
September 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.

Biochem J 2016 06 8;473(12):1733-44. Epub 2016 Apr 8.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia Department of Medical Biology, University of Melbourne, Parkville, Victoria 3050, Australia

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http://dx.doi.org/10.1042/BCJ20160189DOI Listing
June 2016

Flicking the molecular switch underlying MLKL-mediated necroptosis.

Mol Cell Oncol 2015 Jul-Sep;2(3):e985550. Epub 2015 Jan 23.

Cell Signalling and Cell Death Division; The Walter and Eliza Hall Institute of Medical Research; Parkville, Australia; Department of Medical Biology; University of Melbourne; Parkville, Victoria, Australia.

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http://dx.doi.org/10.4161/23723556.2014.985550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905300PMC
June 2016

Molecular Mechanism of CCAAT-Enhancer Binding Protein Recruitment by the TRIB1 Pseudokinase.

Structure 2015 Nov 9;23(11):2111-21. Epub 2015 Oct 9.

Biochemistry Department, Otago School of Medical Sciences, University of Otago, PO Box 56, Dunedin 9054, New Zealand. Electronic address:

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http://www.cell.com/structure/pdf/S0969-2126(15)00367-6.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S096921261500367
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http://dx.doi.org/10.1016/j.str.2015.08.017DOI Listing
November 2015

The molecular regulation of Janus kinase (JAK) activation.

Biochem J 2014 Aug;462(1):1-13

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1042/BJ20140712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112375PMC
August 2014

An exported kinase (FIKK4.2) that mediates virulence-associated changes in Plasmodium falciparum-infected red blood cells.

Int J Parasitol 2014 Apr 14;44(5):319-28. Epub 2014 Feb 14.

Department of Microbiology, School of Biomedical Sciences, Monash University, Victoria 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ijpara.2014.01.003DOI Listing
April 2014

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.

Immunity 2013 Sep 5;39(3):443-53. Epub 2013 Sep 5.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3050, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2013.06.018DOI Listing
September 2013

Techniques to examine nucleotide binding by pseudokinases.

Biochem Soc Trans 2013 Aug;41(4):975-80

Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1042/BST20130075DOI Listing
August 2013

Regulation of Janus kinases by SOCS proteins.

Biochem Soc Trans 2013 Aug;41(4):1042-7

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1042/BST20130077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773493PMC
August 2013

Production and crystallization of recombinant JAK proteins.

Methods Mol Biol 2013 ;967:275-300

Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-62703-242-1_20DOI Listing
June 2013

Plasmodium kinases as targets for new-generation antimalarials.

Future Med Chem 2012 Dec;4(18):2295-310

Department of Biochemistry & Molecular Biology, School of Biomedical Sciences, Monash University, Wellington Road, Clayton VIC, 3800, Australia.

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http://dx.doi.org/10.4155/fmc.12.183DOI Listing
December 2012

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

J Mol Biol 2009 Mar 29;387(1):219-32. Epub 2009 Jan 29.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S00222836090009
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http://dx.doi.org/10.1016/j.jmb.2009.01.041DOI Listing
March 2009

Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state.

J Biol Chem 2009 Jan 4;284(1):284-91. Epub 2008 Nov 4.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M807850200
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http://dx.doi.org/10.1074/jbc.M807850200DOI Listing
January 2009

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.

J Mol Biol 2007 Mar 20;367(3):839-47. Epub 2007 Jan 20.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360700076
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http://dx.doi.org/10.1016/j.jmb.2007.01.036DOI Listing
March 2007

Hijacking of a substrate-binding protein scaffold for use in mycobacterial cell wall biosynthesis.

J Mol Biol 2006 Jun 25;359(4):983-97. Epub 2006 Apr 25.

The Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Vic. 3800, Australia.

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http://dx.doi.org/10.1016/j.jmb.2006.04.012DOI Listing
June 2006

Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function.

Mol Microbiol 2006 May;60(3):591-601

Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Vic. 3800, Australia.

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http://doi.wiley.com/10.1111/j.1365-2958.2006.05120.x
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http://dx.doi.org/10.1111/j.1365-2958.2006.05120.xDOI Listing
May 2006

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor.

Blood 2006 Jan 20;107(1):176-83. Epub 2005 Sep 20.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1182/blood-2005-06-2413DOI Listing
January 2006

Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens.

J Biol Chem 2005 Jan 12;280(4):2503-11. Epub 2004 Nov 12.

Department of Microbiology, Australian Bacterial Pathogenesis Program, Monash University, Victoria 3800, Australia.

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http://dx.doi.org/10.1074/jbc.M409702200DOI Listing
January 2005

DNA binding properties of TnpX indicate that different synapses are formed in the excision and integration of the Tn4451 family.

Mol Microbiol 2004 Aug;53(4):1195-207

Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Victoria 3800, Australia.

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http://dx.doi.org/10.1111/j.1365-2958.2004.04198.xDOI Listing
August 2004

The large resolvase TnpX is the only transposon-encoded protein required for transposition of the Tn4451/3 family of integrative mobilizable elements.

Mol Microbiol 2004 Mar;51(6):1787-800

Australian Bacterial Pathogenesis Programme, Department of Microbiology, Monash University, Victoria 3800, Australia.

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http://dx.doi.org/10.1111/j.1365-2958.2003.03950.xDOI Listing
March 2004

The FxRxHrS motif: a conserved region essential for DNA binding of the VirR response regulator from Clostridium perfringens.

J Mol Biol 2002 Oct;322(5):997-1011

Bacterial Pathogenesis Research Group, Department of Microbiology, Monash University, 3800 Australia.

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http://dx.doi.org/10.1016/s0022-2836(02)00850-1DOI Listing
October 2002