Publications by authors named "Isabelle Green"

7Publications

Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.

Authors:
Anna A Marusiak Natalie L Stephenson Hayeon Baik Eleanor W Trotter Yaoyong Li Karen Blyth Susan Mason Phil Chapman Lorena A Puto Jon A Read Claire Brassington Hannah K Pollard Chris Phillips Isabelle Green Ross Overman Matthew Collier Ewelina Testoni Crispin J Miller Tony Hunter Owen J Sansom John Brognard

Cancer Res 2016 Feb 4;76(3):724-35. Epub 2015 Dec 4.

Signalling Networks in Cancer Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom.

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February 2016

Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases.

Authors:
Les A Dakin Michael H Block Huawei Chen Erin Code James E Dowling Xiaomei Feng Andrew D Ferguson Isabelle Green Alexander W Hird Tina Howard Erika K Keeton Michelle L Lamb Paul D Lyne Hannah Pollard Jon Read Allan J Wu Tao Zhang Xiaolan Zheng

Bioorg Med Chem Lett 2012 Jul 6;22(14):4599-604. Epub 2012 Jun 6.

Oncology iMed Sciences Group, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, MA 02451, USA.

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July 2012

Co-expression of protein phosphatases in insect cells affects phosphorylation status and expression levels of proteins.

Authors:
Rebecca L Brading W Mark Abbott Isabelle Green Alison Davies Eileen J McCall

Protein Expr Purif 2012 Jun 21;83(2):217-25. Epub 2012 Apr 21.

Faculty of Life Sciences, Manchester University, UK.

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June 2012

Structural basis of substrate methylation and inhibition of SMYD2.

Authors:
Andrew D Ferguson Nicholas A Larsen Tina Howard Hannah Pollard Isabelle Green Christie Grande Tony Cheung Renee Garcia-Arenas Scott Cowen Jiaquan Wu Robert Godin Huawei Chen Nicholas Keen

Structure 2011 Sep 21;19(9):1262-73. Epub 2011 Jul 21.

DECS Structural Chemistry, AstraZeneca, Waltham, MA 02451, USA.

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September 2011

Discovery of 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a novel inhibitor of the Jak/Stat pathway.

Authors:
Stephanos Ioannidis Michelle L Lamb Tao Wang Lynsie Almeida Michael H Block Audrey M Davies Bo Peng Mei Su Hai-Jun Zhang Ethan Hoffmann Caroline Rivard Isabelle Green Tina Howard Hannah Pollard Jon Read Marat Alimzhanov Geraldine Bebernitz Kirsten Bell Minwei Ye Dennis Huszar Michael Zinda

J Med Chem 2011 Jan 7;54(1):262-76. Epub 2010 Dec 7.

Department of Cancer Chemistry, AstraZeneca R&D, Boston, Massachusetts, United States.

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January 2011

Inhibitors of the tyrosine kinase EphB4. Part 3: identification of non-benzodioxole-based kinase inhibitors.

Authors:
Catherine Bardelle Bernard Barlaam Nigel Brooks Tanya Coleman Darren Cross Richard Ducray Isabelle Green Christine Lambert-van der Brempt Annie Olivier Jon Read

Bioorg Med Chem Lett 2010 Nov 16;20(21):6242-5. Epub 2010 Sep 16.

AstraZeneca, Mereside, Alderley Park, Macclesfield SK10 4TG, UK.

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November 2010

Protein transduction domains: are they delivering?

Authors:
Isabelle Green Richard Christison Catherine J Voyce Ken R Bundell Mark A Lindsay

Trends Pharmacol Sci 2003 May;24(5):213-5

EST-Biology, AstraZeneca Pharmaceuticals, Mereside, Alderley Park, Cheshire SK10 4TG, UK.

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May 2003