Isabelle Fruh

Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units.

Authors:

Elisa Giorgetti Moh Panesar Yunyu Zhang Stefanie Joller Marie Ronco Michael Obrecht Christian Lambert Nathalie Accart Nicolau Beckmann Arno Doelemeyer Ludovic Perrot Isabelle Fruh Matthias Mueller Eliane Pierrel Serge Summermatter Michael Bidinosti Derya R Shimshek Sophie Brachat Mark Nash

Cell Rep 2019 Nov;29(6):1539-1554.e7

Musculoskeletal Diseases Area, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland. Electronic address:

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November 2019

Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo.

Authors:

Oliver M Russell Isabelle Fruh Pavandeep K Rai David Marcellin Thierry Doll Amy Reeve Mitchel Germain Julie Bastien Karolina A Rygiel Raffaele Cerino Andreas W Sailer Majlinda Lako Robert W Taylor Matthias Mueller Robert N Lightowlers Doug M Turnbull Stephen B Helliwell

Sci Rep 2018 01 29;8(1):1799. Epub 2018 Jan 29.

Novartis Institutes for BioMedical Research, Novartis Campus, Basel, CH-4056, Switzerland.

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January 2018

CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations.

Stem Cell Reports 2016 12 10;7(6):1059-1071. Epub 2016 Nov 10.

Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland. Electronic address:

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December 2016

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.

Science 2016 Mar 4;351(6278):1199-203. Epub 2016 Feb 4.

Developmental Molecular Pathways, Novartis Institutes for Biomedical Research, Basel, Switzerland.

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March 2016

Identification of Small Molecules Which Induce Skeletal Muscle Differentiation in Embryonic Stem Cells via Activation of the Wnt and Inhibition of Smad2/3 and Sonic Hedgehog Pathways.

Authors:

Hyunwoo Lee Corinne Haller Carole Manneville Thierry Doll Isabelle Fruh Caroline Gubser Keller Shola M Richards Yvonne Ibig-Rehm Maude Patoor Marjo Goette Laure C Bouchez Matthias Mueller

Stem Cells 2016 Feb 17;34(2):299-310. Epub 2015 Nov 17.

Developmental and Molecular Pathways, Basel, Switzerland.

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February 2016

High-Throughput Screening Using iPSC-Derived Neuronal Progenitors to Identify Compounds Counteracting Epigenetic Gene Silencing in Fragile X Syndrome.

Authors:

Markus Kaufmann Ansgar Schuffenhauer Isabelle Fruh Jessica Klein Anke Thiemeyer Pierre Rigo Baltazar Gomez-Mancilla Valerie Heidinger-Millot Tewis Bouwmeester Ulrich Schopfer Matthias Mueller Barna D Fodor Amanda Cobos-Correa

J Biomol Screen 2015 Oct 29;20(9):1101-11. Epub 2015 May 29.

Center of Proteomic Chemistry, Novartis Institutes for Biomedical Research, Novartis Campus, Basel, Switzerland

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October 2015

Publications by authors named "Isabelle Fruh"

Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units.

Authors:

Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo.

Authors:

CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations.

Authors:

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.

Authors:

Identification of Small Molecules Which Induce Skeletal Muscle Differentiation in Embryonic Stem Cells via Activation of the Wnt and Inhibition of Smad2/3 and Sonic Hedgehog Pathways.

Authors:

High-Throughput Screening Using iPSC-Derived Neuronal Progenitors to Identify Compounds Counteracting Epigenetic Gene Silencing in Fragile X Syndrome.

Authors: