Isabelle Florent

Isabelle Florent

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Isabelle Florent

Isabelle Florent

Publications by authors named "Isabelle Florent"

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Why the -omic future of Apicomplexa should include gregarines.

Biol Cell 2020 Mar 16. Epub 2020 Mar 16.

Molécules de Communication et Adaptation des Microorganismes (MCAM, UMR 7245), Département Adaptations du Vivant (AVIV), Muséum National d'Histoire Naturelle, CNRS, Paris, Cedex 05, France.

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http://dx.doi.org/10.1111/boc.202000006DOI Listing
March 2020

Aminobenzosuberone derivatives as PfA-M1 inhibitors: Molecular recognition and antiplasmodial evaluation.

Bioorg Chem 2020 Mar 11;98:103750. Epub 2020 Mar 11.

Université de Haute-Alsace, Université de Strasbourg, CNRS, LIMA UMR 7042, F-68000 Mulhouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2020.103750DOI Listing
March 2020

Metallopeptidases of Toxoplasma gondii: in silico identification and gene expression.

Parasite 2018 8;25:26. Epub 2018 May 8.

EA 7510, ESCAPE, Laboratory of Parasitology-Mycology, University of Reims Champagne-Ardenne, 51100 Reims, France - Laboratory of Parasitology-Mycology, Toxoplasmosis National Reference Center, Toxoplasma Biological Resource Center, Maison Blanche Hospital, 51100 Reims, France.

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http://dx.doi.org/10.1051/parasite/2018025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939537PMC
January 2019

Bile Salt Hydrolase Activities: A Novel Target to Screen Anti- Lactobacilli?

Front Microbiol 2018 8;9:89. Epub 2018 Feb 8.

INRA, Commensal and Probiotics-Host Interactions Laboratory, Micalis Institute, AgroParisTech, Paris, France.

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http://dx.doi.org/10.3389/fmicb.2018.00089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809405PMC
February 2018

Bile-Salt-Hydrolases from the Probiotic Strain La1 Mediate Anti-giardial Activity and .

Front Microbiol 2017 31;8:2707. Epub 2018 Jan 31.

UMR7245, Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique, Sorbonne-Universités, Paris, France.

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http://dx.doi.org/10.3389/fmicb.2017.02707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810305PMC
January 2018

Discovery of novel non-competitive inhibitors of mammalian neutral M1 aminopeptidase (APN).

Biochimie 2017 Nov 28;142:216-225. Epub 2017 Sep 28.

Instituto de Biotecnología, Universidad Nacional Autónoma de México (UNAM), Ave Universidad 2001, Cuernavaca, Morelos, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2017.09.015DOI Listing
November 2017

KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.

Bioorg Med Chem 2017 09 4;25(17):4628-4636. Epub 2017 Jul 4.

Departamento de Biociências, Universidade Federal de São Paulo, R. Silva Jardim, 136, 11015-020, Vila Mathias, Santos, São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.06.047DOI Listing
September 2017

Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo.

Malar J 2017 09 21;16(1):382. Epub 2017 Sep 21.

Molécules de Communication et Adaptation des Microorganismes, (MCAM, UMR7245), Muséum National Histoire Naturelle, Sorbonne Universités, CNRS, CP 52, 57 Rue Cuvier, 75005, Paris, France.

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http://dx.doi.org/10.1186/s12936-017-2032-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609037PMC
September 2017

Diversity of apostome ciliates, Chromidina spp. (Oligohymenophorea, Opalinopsidae), parasites of cephalopods of the Mediterranean Sea.

Parasite 2016 17;23:33. Epub 2016 Aug 17.

UMR 7245 CNRS MCAM, Muséum National d'Histoire Naturelle, Sorbonne Universités, CP 52, 57 rue Cuvier, 75005 Paris, France.

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http://dx.doi.org/10.1051/parasite/2016033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988119PMC
August 2017

Comparative Antibody Responses Against three Antimalarial Vaccine Candidate Antigens from Urban and Rural Exposed Individuals in Gabon.

Eur J Microbiol Immunol (Bp) 2016 Dec 3;6(4):287-297. Epub 2016 Nov 3.

Unité de Parasitologie Médicale (UPARAM), Centre International de Recherches Médicales de Franceville (CIRMF), BP 769 Franceville, Gabon; Département de Parasitologie-Mycologie, Université des Sciences de la Santé, BP 4008 Libreville, Gabon.

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http://dx.doi.org/10.1556/1886.2016.00027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146647PMC
December 2016

Immunoglobulin response to the low polymorphic Pf113 antigen in children from Lastoursville, South-East of Gabon.

Acta Trop 2016 Nov 12;163:149-56. Epub 2016 Aug 12.

Centre International de Recherches Médicales de Franceville (CIRMF), Unité de Parasitologie Médicale (UPARAM), BP 769 Franceville, Gabon; Département de Parasitologie-Mycologie Médecine Tropicale, Faculté de Médecine, Université des Sciences de la Santé, BP 4009 Libreville, Gabon. Electronic address:

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http://dx.doi.org/10.1016/j.actatropica.2016.08.014DOI Listing
November 2016

Redescription of Dicyemennea eledones (Wagener, 1857) (Phylum Dicyemida) from Eledone cirrhosa (Lamarck, 1798) (Mollusca: Cephalopoda: Octopoda).

Syst Parasitol 2016 11 14;93(9):905-915. Epub 2016 Oct 14.

Department of Biology, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan.

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http://dx.doi.org/10.1007/s11230-016-9659-3DOI Listing
November 2016

Genetic impairment of parasite myosin motors uncovers the contribution of host cell membrane dynamics to Toxoplasma invasion forces.

BMC Biol 2016 11 9;14(1):97. Epub 2016 Nov 9.

Institute for Advanced Biosciences, Team Cell & Membrane Dynamics of Host-Parasite Interactions, INSERM U1209, 38000, Grenoble, France.

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http://dx.doi.org/10.1186/s12915-016-0316-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101828PMC
November 2016

Deconjugated Bile Salts Produced by Extracellular Bile-Salt Hydrolase-Like Activities from the Probiotic La1 Inhibit Growth.

Front Microbiol 2016 27;7:1453. Epub 2016 Sep 27.

MCAM UMR 7245, Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique, Sorbonne Universités Paris, France.

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http://dx.doi.org/10.3389/fmicb.2016.01453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037171PMC
September 2016

Ultrastructure of Selenidium pendula, the Type Species of Archigregarines, and Phylogenetic Relations to Other Marine Apicomplexa.

Protist 2016 08 18;167(4):339-368. Epub 2016 Jun 18.

Sorbonne Universités, Université Pierre et Marie Curie - Paris 6, CNRS, UMR 7144, Station Biologique de Roscoff, Place Georges Teissier, CS90074, 29688 Roscoff cedex, France.

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http://dx.doi.org/10.1016/j.protis.2016.06.001DOI Listing
August 2016

A new lactobacilli in vivo expression system for the production and delivery of heterologous proteins at mucosal surfaces.

FEMS Microbiol Lett 2016 07 1;363(13). Epub 2016 May 1.

Micalis Institute, INRA, AgroParisTech, Paris-Saclay University, Domaine de Vilvert, 78350 Jouy-en-Josas, France

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http://dx.doi.org/10.1093/femsle/fnw117DOI Listing
July 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Access to new endoperoxide derivatives by electrochemical oxidation of substituted 3-azabicyclo[4.1.0]hept-4-enes.

Chemistry 2015 Mar 20;21(14):5584-93. Epub 2015 Feb 20.

Institut de Chimie des Substances Naturelles, (CNRS) UPR 2301, Centre de Recherche de Gif - 1, av. de la Terrasse, 91198 Gif-sur-Yvette (France).

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http://dx.doi.org/10.1002/chem.201406138DOI Listing
March 2015

Cycloartane triterpenes from the leaves of Neoboutonia macrocalyx L.

Phytochemistry 2014 Jun 25;102:189-96. Epub 2014 Mar 25.

College of Veterinary Medicine, Animal Resources and Biosecurity, P.O. Box 7062, Kampala, Uganda.

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http://dx.doi.org/10.1016/j.phytochem.2014.02.005DOI Listing
June 2014

Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors.

J Med Chem 2012 Dec 5;55(24):10909-17. Epub 2012 Dec 5.

INSERM U761, Biostructures and Drug Discovery and Faculté de Pharmacie, Université Lille Nord de France, 3 rue du Pr Laguesse, Lille F-59000, France.

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http://dx.doi.org/10.1021/jm301506hDOI Listing
December 2012

Probiotics for the control of parasites: an overview.

J Parasitol Res 2011 28;2011:610769. Epub 2011 Sep 28.

Team Adaptation of Protozoa to their Environment, UMR 7245 CNRS, National Museum of Natural History, CP52, 61 rue Buffon, 75231 Paris Cedex 05, France.

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http://dx.doi.org/10.1155/2011/610769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182331PMC
November 2011

Aminocyclopropanes as precursors of endoperoxides with antimalarial activity.

Org Biomol Chem 2010 Dec 11;8(24):5591-601. Epub 2010 Oct 11.

Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France.

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http://dx.doi.org/10.1039/c0ob00308eDOI Listing
December 2010

Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole.

Malar J 2010 Jun 30;9:189. Epub 2010 Jun 30.

FRE3206 CNRS/MNHN, Department Regulations, Development, Molecular Diversity, CP52, 61 rue Buffon, F-75005 Paris, France.

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http://dx.doi.org/10.1186/1475-2875-9-189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914058PMC
June 2010

Assessing functional annotation transfers with inter-species conserved coexpression: application to Plasmodium falciparum.

BMC Genomics 2010 Jan 15;11:35. Epub 2010 Jan 15.

Méthodes et algorithmes pour la Bioinformatique, LIRMM, Univ, Montpellier 2, CNRS; 161 rue Ada, 34392 MONTPELLIER, France.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
Publisher Site
http://dx.doi.org/10.1186/1471-2164-11-35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826313PMC
January 2010

Plasmodium falciparum: functional mitochondrial ADP/ATP transporter in Escherichia coli plasmic membrane as a tool for selective drug screening.

Exp Parasitol 2008 Feb 28;118(2):181-7. Epub 2007 Aug 28.

Biologie Fonctionnelle des Protozoaires, USM504-EA3335, Département Régulations, Développement, Diversité Moléculaire, Muséum National d'Histoire Naturelle, 61 rue Buffon, 75005 Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00144894070020
Publisher Site
http://dx.doi.org/10.1016/j.exppara.2007.07.015DOI Listing
February 2008

Characterization of PfDYN2, a dynamin-like protein of Plasmodium falciparum expressed in schizonts.

Microbes Infect 2007 Jun 1;9(7):797-805. Epub 2007 Mar 1.

USM504-EA3335, RDDM, Muséum National d'Histoire Naturelle, 61, rue Buffon, CP52, 75231 Paris cedex 05, France.

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http://dx.doi.org/10.1016/j.micinf.2007.02.020DOI Listing
June 2007

Biochemical properties and cellular localization of Plasmodium falciparum protein disulfide isomerase.

Biochimie 2007 Mar 27;89(3):337-46. Epub 2006 Nov 27.

USM 0504 Biologie Fonctionnelle des Protozoaires, EA3335, Département Régulations, Développement, Diversité Moléculaire, CP 52, Muséum National d'Histoire Naturelle, 75231 Paris cedex 05, France.

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http://dx.doi.org/10.1016/j.biochi.2006.11.001DOI Listing
March 2007

Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.

J Med Chem 2007 Mar 28;50(6):1322-34. Epub 2007 Feb 28.

Inserm, U761, Biostructures and Drug Discovery, Lille F-59006 France.

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http://dx.doi.org/10.1021/jm061169bDOI Listing
March 2007

Labelling of four distinct trophozoite falcipains of Plasmodium falciparum by a cystatin-derived probe.

Biol Chem 2005 Apr;386(4):401-6

Biologie Fonctionnelle des Protozoaires, Département Régulation, Dévelopement, Diversité Moléculaire, Muséum National d'Histoire Naturelle, 61, rue Buffon, F-75005 Paris, France.

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http://dx.doi.org/10.1515/BC.2005.048DOI Listing
April 2005

Plasmodium falciparum genes differentially expressed during merozoite morphogenesis.

Mol Biochem Parasitol 2004 May;135(1):143-8

Biologie Fonctionnelle des Protozoaires, USM504/EA3335, Département Regulations Développement Diversité Moléculaire, Muséum National d'Histoire Naturelle, 61 rue Buffon, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.molbiopara.2003.12.010DOI Listing
May 2004

Design, synthesis and antimalarial activity of novel, quinoline-based, zinc metallo-aminopeptidase inhibitors.

Bioorg Med Chem Lett 2003 Aug;13(16):2659-62

UMR CNRS 8525, Institut Pasteur et Institut de Biologie de Lille, Université de Lille 2, Lille, France.

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http://dx.doi.org/10.1016/s0960-894x(03)00550-xDOI Listing
August 2003