Publications by authors named "Isabelle Brun-Heath"

18Publications

Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs.

J Chem Inf Model 2020 12 16;60(12):5730-5734. Epub 2020 Jul 16.

Joint IRB-BSC-CRG Program in Computational Biology, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10-12, 08020 Barcelona, Catalonia, Spain.

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December 2020

Nucleosome Dynamics: a new tool for the dynamic analysis of nucleosome positioning.

Nucleic Acids Res 2019 10;47(18):9511-9523

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, Barcelona 08028, Spain.

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October 2019

Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope.

Proc Natl Acad Sci U S A 2019 05 26;116(20):10009-10018. Epub 2019 Apr 26.

Institute for Research in Biomedicine (IRB Barcelona), the Barcelona Institute of Science and Technology, 08028 Barcelona, Catalonia, Spain;

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May 2019

A multifunctional toolkit for target-directed cancer therapy.

Chem Commun (Camb) 2019 Jan;55(6):802-805

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Joint IRB-BSC Program in Computational Biology, Baldiri Reixac 10-12, 08028 Barcelona, Spain.

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January 2019

Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators.

Structure 2018 01 7;26(1):145-152.e3. Epub 2017 Dec 7.

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028 Barcelona, Spain; ICREA, Passeig Lluís Companys 23, 08010 Barcelona, Spain. Electronic address:

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January 2018

Efficient siRNA-peptide conjugation for specific targeted delivery into tumor cells.

Chem Commun (Camb) 2017 Mar;53(19):2870-2873

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Joint IRB-BSC Program in Computational Biology, Baldiri Reixac 10-12, 08028 Barcelona, Spain.

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March 2017

Rational design of novel N-alkyl-N capped biostable RNA nanostructures for efficient long-term inhibition of gene expression.

Nucleic Acids Res 2016 05 14;44(9):4354-67. Epub 2016 Mar 14.

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Joint IRB-BSC Program in Computational Biology, Baldiri Reixac 10-12, 08028 Barcelona, Spain Barcelona Supercomputing Center, Jordi Girona 29, 08034 Barcelona, Spain Department of Biochemistry and Molecular Biology, University of Barcelona, 08028 Barcelona, Spain

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May 2016

Differential expression of the bone and the liver tissue non-specific alkaline phosphatase isoforms in brain tissues.

Cell Tissue Res 2011 Mar 31;343(3):521-36. Epub 2010 Dec 31.

Unité de Pathologie Cellulaire et Génétique, UPRES-EA2493, Université de Versailles Saint Quentin en Yvelines, 78035 Versailles, France.

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March 2011

Delayed transport of tissue-nonspecific alkaline phosphatase with missense mutations causing hypophosphatasia.

Eur J Med Genet 2007 Sep-Oct;50(5):367-78. Epub 2007 Jul 21.

Equipe Structure-Fonction et Génétique, EA 2493, CHU Paris Ile de France Ouest, Université de Versailles-Saint Quentin en Yvelines, France.

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November 2007

Characterization of 11 novel mutations in the tissue non-specific alkaline phosphatase gene responsible for hypophosphatasia and genotype-phenotype correlations.

Mol Genet Metab 2005 Mar 19;84(3):273-7. Epub 2004 Dec 19.

Equipe Structure-Fonction et Génétique, EA 2493, CHU Paris Ile de France Ouest, Université de Versailles-Saint Quentin en Yvelines, France.

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March 2005