Publications by authors named "Isabelle Arnulf"

100Publications

Speculating on Kleine-Levin Syndrome mechanisms.

J Clin Sleep Med 2021 Jan 8. Epub 2021 Jan 8.

National Reference Center for Kleine-Levin syndrome, Sleep Disorders Unit, Pitie-Salpetriere Hospital, APHP-Sorbonne, Paris, France.

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January 2021

Parkinson Disease Propagation Using MRI Biomarkers and Partial Least Squares Path Modeling.

Neurology 2020 Dec 4. Epub 2020 Dec 4.

From the Institut Cerveau Moelle (N.P., L.Y.-C., R.V., R.G., S.F.-V., S.L.), Centre de NeuroImagerie de Recherche; Sorbonne Université (N.P., L.Y.-C,, R.G., F.G., C.E., C.G., S.F.-V., I.A., M.V., S.L.), Paris 06, UMR S 1127, CNRS UMR 7225, Institut Cerveau Moelle, F-75013; Institut Cerveau Moelle Team Movement Investigation and Therapeutics (N.P., R.G., F.G., C.E., C.G., I.A., M.V., S.L.); Service de neuroradiologie (N.P., M.V., S.L.), APHP, Pitié-Salpêtrière; and Clinique des Mouvements Anormaux (C.E.), Département des Maladies du Système Nerveux, and Service des Pathologies du Sommeil (I.A.), Hôpital Pitié-Salpêtrière, APHP, Paris, France.

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December 2020

Successful treatment of drug-resistant cataplexy with the anticholinergic drug tropatepine.

J Clin Sleep Med 2020 Nov 24. Epub 2020 Nov 24.

National Reference Center for Narcolepsy, Sleep Disorders Unit, University Hospital Pitié-Salpêtrière, Paris, France.

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November 2020

A strange New Year's Eve: triggers in Kleine-Levin syndrome.

J Clin Sleep Med 2020 Oct 7. Epub 2020 Oct 7.

National Reference Center for Kleine-Levin syndrome, France.

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October 2020

N3 sleep with rapid eye movements in a PCDH19 mutation: a new dissociate state between N3 and REM sleep.

Sleep Med 2020 10 26;74:341-342. Epub 2020 Aug 26.

Sleep Disorders Unit, Pitie-Salpetriere Hospital, AP-HP Sorbonne, Paris, France. Electronic address:

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October 2020

Dreams and nightmares in healthy adults and in patients with sleep and neurological disorders.

Lancet Neurol 2020 10 16;19(10):849-859. Epub 2020 Sep 16.

Paris Brain Institute, Paris, France; Sorbonne University, Paris, France; Sleep Disorders Unit, Assistance Publique Hôpitaux de Paris, Paris, France. Electronic address:

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October 2020

Idiopathic Hypersomnia and Other Hypersomnia Syndromes.

Neurotherapeutics 2020 Sep 8. Epub 2020 Sep 8.

Service des Pathologies du Sommeil, Centre National de Reference des Hypersomnies Rares, Hôpitaux Universitaires Pitié-Salpêtrière, Sorbonne Université, Paris, 75013, France.

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September 2020

Maintenance of wakefulness test: how does it predict accident risk in patients with sleep disorders?

Sleep Med 2020 Apr 20. Epub 2020 Apr 20.

Reference National Center for Narcolepsy, Sleep Unit, CHU Montpellier, Montpellier, France; PSNREC, Univ Montpellier, INSERM, Montpellier, France.

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April 2020

Narcolepsy with cataplexy: Does age at diagnosis change the clinical picture?

CNS Neurosci Ther 2020 Aug 6. Epub 2020 Aug 6.

Integrative Physiology of the Brain Arousal Systems, CRNL, INSERM-U1028, CNRS UMR5292, University of Lyon 1, Lyon, France.

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August 2020

variants in REM sleep behavior disorder: A multicenter study.

Neurology 2020 08 26;95(8):e1008-e1016. Epub 2020 Jun 26.

From the Department of Human Genetics (L.K., U.R., G.A.R., Z.G.-O.), Montreal Neurological Institute (L.K., J.A.R., U.R., E.L., F.A., R.B.P., G.A.R., Z.G.-O.), and Department of Neurology and Neurosurgery (J.A.R., F.A., R.B.P., G.A.R., Z.G.-O.), McGill University, Montréal; Oxford Parkinson's Disease Centre (M.T.M.H.) and Nuffield Department of Clinical Neurosciences (M.T.M.H.), University of Oxford, UK; Sleep Disorders Unit (I.A.), Pitié Salpêtrière Hospital, Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière and Sorbonne Universities, Paris; National Reference Center for Narcolepsy, Sleep Unit (Y.D.), Department of Neurology, Gui-de-Chauliac Hospital, CHU Montpellier, University of Montpellier, Inserm U1061, France; Sleep Disorders Unit, Department of Neurology (B.H., A.S.), Medical University of Innsbruck, Austria; Department of Clinical Neurophysiology and Sleep Center (C.C.M.), University Lille North of France, CHU Lille; Sleep Disorder Unit (B.A.), Carémeau Hospital, University Hospital of Nîmes, France; Department of Biomedical and Neuromotor Sciences (DIBINEM) (G.P., E.A.), Alma Mater Studiorum, University of Bologna; IRCCS (G.P., E.A.), Istituto delle Scienze Neurologiche, Bologna; Department of Neurological Sciences (L.F.-S.), Università Vita-Salute San Raffaele, Milan, Italy; Department of Neurology with Institute of Translational Neurology (A.H.), University of Muenster, Germany; Department of Neurology (B.F.B.), Mayo Clinic, Rochester, MN; UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders (A.J.E.), Cincinnati, OH; Sleep and Neurology Unit (V.C.D.C.), Beau Soleil Clinic, Montpellier; EuroMov (V.C.D.C.), University of Montpellier, France; Paracelsus-Elena-Klinik (B.M., F.S.-D., C.T.), Kassel; Department of Neurology (B.M., C.T.), University Medical Centre Goettingen; Department of Neurology (F.S.-D., W.O.), Philipps University, Marburg, Germany; Department of Neurology and Centre of Clinical Neuroscience (K.S., D.K.), Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic; Department of Medical Sciences and Public Health, Sleep Disorder Research Center (M.F., M.P.), University of Cagliari, Italy; Laboratory for Sleep Disorders (F.D., M.V.) and Department of Neurology (F.D., M.V.), St. Dimpna Regional Hospital, Geel, Belgium; Department of Medicine (DAME) (M.T., M.V.), University of Udine, Italy; Department of Clinical and Movement Neurosciences (M.T.), UCL Queen Square Institute of Neurology, London, UK; Clinical Neurology Unit (G.L.G., M.V.), Department of Neurosciences, University Hospital of Udine; DMIF (G.L.G.), University of Udine, Italy; Centre d'Études Avancées en Médecine du Sommeil (J.-F.G., A.D., J.Y.M., R.B.P.), Hôpital du Sacré-Cœur de Montréal; and Departments of Psychology (J.-F.G.), Neurosciences (A.D.), and Psychiatry (J.Y.M.), Université du Québec à Montréal, Canada.

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August 2020

Blackout of my nights: Contentless, timeless and selfless report from the night in patients with central hypersomnias.

Conscious Cogn 2020 05 24;81:102931. Epub 2020 Apr 24.

Sorbonne University, Paris, France; Paris Brain Institute (IHU@ICM; Inserm UMR_S 975; CNRS UMR 7225), Paris, France; Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France; National Reference Center on Narcolepsy and Rare Hypersomnias, France. Electronic address:

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May 2020

Simple behavioral criteria for the diagnosis of disorders of arousal.

J Clin Sleep Med 2020 01 4;16(1):121-128. Epub 2019 Dec 4.

AP-HP, Pitié -Salpêtrière Hospital, Sleep Disorders Unit, Paris, France.

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January 2020

Evening sock marks as an adjunct to the clinical prediction of obstructive sleep apnea.

Sleep Breath 2020 Dec 8;24(4):1365-1371. Epub 2019 Dec 8.

Service de Pathologies du Sommeil, Département R3S, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Paris, France.

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December 2020

Secondary hypersomnia as an initial manifestation of neuromyelitis optica spectrum disorders.

Mult Scler Relat Disord 2020 Feb 25;38:101869. Epub 2019 Nov 25.

Département de neurologie, Hôpital de la pitié salpêtrière, APHP, Sorbonne Université, Paris 75013, France.

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February 2020

Postural preinspiratory cortical activity, genioglossus activity and fluid shift in awake obstructive sleep apnoea patients.

Exp Physiol 2020 02 9;105(2):370-378. Epub 2019 Dec 9.

Sorbonne Université, INSERM, UMRS 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.

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February 2020

Abnormal Activity of Neck Inspiratory Muscles during Sleep as a Prognostic Indicator in Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2020 02;201(4):414-422

UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, INSERM, Sorbonne Université, Paris, France.

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February 2020

Overt replay during REM sleep of the UPDRS finger taps sequence in a patient with REM sleep behavior disorder.

Sleep Med 2019 11 8;63:38-40. Epub 2019 Jun 8.

Sleep Disorder Unit, Pitié-Salpêtrière, University Hospital, APHP, Paris, France; Sorbonne University, Paris, France; Brain and Spine Institute - ICM, IHU@ICM, Paris, France. Electronic address:

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November 2019

Precision Medicine for Idiopathic Hypersomnia.

Sleep Med Clin 2019 Sep;14(3):333-350

National Reference Center for Rare Hypersomnias, Pitie-Salpetriere University Hospital, APHP, and Sorbonne University, 47-83 Boulevard de l'Hôpital, Paris 75013, France.

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September 2019

Mandibular advancement reveals long-term suppression of breathing discomfort in patients with obstructive sleep apnea syndrome.

Respir Physiol Neurobiol 2019 05 11;263:47-54. Epub 2019 Mar 11.

Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, F-75005, Paris, France; AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie, Médecine Intensive et Réanimation (Département "R3S"), F-75013, Paris, France. Electronic address:

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May 2019

Postural respiratory-related cortical activation and rostral fluid shift in awake healthy humans.

Exp Physiol 2019 06 20;104(6):887-895. Epub 2019 Mar 20.

Sorbonne Université, INSERM UMRS 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.

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June 2019

Smiling asleep: A study of happy emotional expressions during adult sleep.

J Sleep Res 2019 08 6;28(4):e12814. Epub 2019 Jan 6.

Sleep Disorder Unit, Pitie-Salpetriere University Hospital, APHP, Paris, France.

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August 2019

Sleepwalking.

Authors:
Isabelle Arnulf

Curr Biol 2018 11 19;28(22):R1288-R1289. Epub 2018 Nov 19.

Institut du Cerveau et de la Moelle, Sorbonne University, Pitié Salpêtrière Hospital, Paris, France. Electronic address:

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November 2018

Michel Jouvet: an explorer of dreams and a great storyteller.

Sleep Med 2018 09 6;49:4-9. Epub 2018 Jun 6.

INSERM/UCBL-U628, Physiologie intégrée du système d'éveil, Lyon, France.

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September 2018

Emerging psychiatric disorders in Kleine-Levin syndrome.

J Sleep Res 2018 10 14;27(5):e12690. Epub 2018 Apr 14.

National Reference Centre for Narcolepsy, Hypersomnia and Kleine-Levin Syndrome, Pitie-Salpetriere University Hospital, AP-HP, Paris, France.

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October 2018

Author Correction: REM sleep respiratory behaviours match mental content in narcoleptic lucid dreamers.

Sci Rep 2018 Apr 12;8(1):6128. Epub 2018 Apr 12.

Sorbonne Université, IHU@ICM, INSERM, CNRS UMR7225, équipe MOV'IT, F-75013, Paris, France.

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April 2018

Rapid eye movement sleep behavior disorder or epileptic seizure during sleep? A video analysis of motor events.

Seizure 2018 May 21;58:1-5. Epub 2018 Mar 21.

Sorbonne Universitiés, UPMC Univ. Paris 06, F-75005, Paris, France; Brain and Spine Institute (ICM, INSERM UMRS1127, INSERM UMRS975, CNRS UMR7225, UPMC) F-75013, Paris, France; AP-HP, GH Pitié-Salpêtrière-Charles Foix Sleep Disorders Unit, F-75013, Paris, France.

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May 2018

LRRK2 protective haplotype and full sequencing study in REM sleep behavior disorder.

Parkinsonism Relat Disord 2018 07 21;52:98-101. Epub 2018 Mar 21.

Montreal Neurological Institute, McGill University, Montréal, QC, H3A 0G4, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, QC, H3A 0G4, Canada, Canada; Department of Human Genetics, McGill University, H3A 0G4, Montréal, QC, Canada. Electronic address:

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July 2018

IV steroids during long episodes of Kleine-Levin syndrome.

Neurology 2018 04 23;90(17):e1488-e1492. Epub 2018 Mar 23.

From the Sleep Disorders Unit (A.L., E.G., C.C., S.L.-S., I.A.), National Reference Center for Narcolepsy, Hypersomnia and Kleine-Levin Syndrome, Brain Research Institute (CRICM, UPMC, Paris 6; Inserm UMR_S 975; CNRS UMR 7225), Sorbonne University Paris; Sleep Medicine and Respiratory Disease Center (L.P.-D.), Competence Center for Narcolepsy, Hypersomnia and Kleine-Levin Syndrome, Hospices Civils de Lyon, France; and Center for Investigation and Research in Sleep (A.O.R.), Lausanne University Hospital and Lausanne University, Switzerland.

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April 2018

Stridor combined with other sleep breathing disorders in multiple system atrophy: a tailored treatment?

Sleep Med 2018 02 8;42:53-60. Epub 2018 Jan 8.

Sleep Disorder Unit, Pitie-Salpetriere Hospital, AP-HP, Paris, France(1); Sorbonne University, Paris, France. Electronic address:

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February 2018

REM sleep respiratory behaviours mental content in narcoleptic lucid dreamers.

Sci Rep 2018 02 8;8(1):2636. Epub 2018 Feb 8.

Sorbonne Université, IHU@ICM, INSERM, CNRS UMR7225, équipe MOV'IT, F-75013 Paris, France.

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February 2018

Complex HLA association in paraneoplastic cerebellar ataxia with anti-Yo antibodies.

J Neuroimmunol 2018 02 18;315:28-32. Epub 2017 Dec 18.

Center for Sleep Sciences and Medicine, Stanford University, 3165 Porter Drive, Palo Alto, CA 94304, USA. Electronic address:

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February 2018

Prevalence and Phenotype of Sleep Disorders in 60 Adults With Prader-Willi Syndrome.

Sleep 2017 12;40(12)

Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pathologies du Sommeil (Département R3S) et Centre de Référence National pour Narcolepsie, Hypersomnie et Syndrome de Kleine-Levin, Paris, France.

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December 2017

Upper airway stabilization by osteopathic manipulation of the sphenopalatine ganglion versus sham manipulation in OSAS patients: a proof-of-concept, randomized, crossover, double-blind, controlled study.

BMC Complement Altern Med 2017 Dec 20;17(1):546. Epub 2017 Dec 20.

Sorbonne Universités, UPMC Université Paris 06, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.

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December 2017

Impact of earplugs and eye mask on sleep in critically ill patients: a prospective randomized study.

Crit Care 2017 Nov 21;21(1):284. Epub 2017 Nov 21.

Neurophysiologie respiratoire expérimentale et clinique, Sorbonne Universités, UPMC Université Paris 06, INSERM, UMRS1158, Paris, France.

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November 2017

"I feel my arm shaking": partial cataplexy mistaken for drug-resistant focal epilepsy.

Sleep Med 2017 08 22;36:119-121. Epub 2017 May 22.

Sleep Disorders Unit, National Reference Center for Narcolepsy, Hypersomnia and Kleine-Levin Syndrome, Pitié-Salpêtrière Hospital, Paris, France.

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August 2017

Dopamine and serotonin levels in cerebrospinal fluid during episodes of Kleine-Levin syndrome.

Sleep Med 2017 08 27;36:184-185. Epub 2017 May 27.

Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, AP-HP, Paris, France; University-Hospital Institute, ICM, UPMC-Paris 6, Inserm U 1127, CNRS UMR 722, Paris, France. Electronic address:

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August 2017

Is there a common motor dysregulation in sleepwalking and REM sleep behaviour disorder?

J Sleep Res 2017 10 17;26(5):614-622. Epub 2017 May 17.

Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, APHP, Paris, France.

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October 2017

Sexsomnia: A Specialized Non-REM Parasomnia?

Sleep 2017 Feb;40(2)

Sleep Disorders Unit and Hospital-University, Pitié-Salpêtrière Hospital (APHP).

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February 2017

Familial idiopathic rapid eye movement sleep behavior disorder.

Sleep Med 2017 02 7;30:29-30. Epub 2016 Jun 7.

Sleep Disorder Unit, Pitie-Salpetriere University Hospital, Paris, France; Pierre and Marie Curie University, Paris, France. Electronic address:

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February 2017

Phasic activity during non REM sleep.

Sleep Med 2017 01 10;29:37-40. Epub 2016 Nov 10.

Sleep Disorders Unit, APHP, Pitié-Salpêtrière Hospital, Paris, France; CRICM, Inserm U975-CNRS, Pierre and Marie Curie University (Sorbonne Universities, Univ Paris 6), Paris, France.

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January 2017

Normal sleep on mechanical ventilation in adult patients with congenital central alveolar hypoventilation (Ondine's curse syndrome).

Orphanet J Rare Dis 2017 01 23;12(1):18. Epub 2017 Jan 23.

Sorbonne Universités, UPMC Université Paris 06, INSERM, UMRS1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France.

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January 2017

Idiopathic REM sleep behavior disorder and neurodegenerative risk: To tell or not to tell to the patient? How to minimize the risk?

Sleep Med Rev 2017 12 10;36:82-95. Epub 2016 Nov 10.

Sleep Disorder Unit, Pitie-Salpetriere Hospital, APHP, Pierre and Marie Curie University, Paris, France. Electronic address:

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December 2017

Predictors of long-term effectiveness to mandibular repositioning device treatment in obstructive sleep apnea patients after 1000 days.

Sleep Med 2016 Nov - Dec;27-28:107-114. Epub 2016 Oct 27.

AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Stomatologie et Chirurgie Maxillo-faciale, 47-83 boulevard de l'hôpital, 75013 Paris, France. Electronic address:

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February 2018

Comorbidity between central disorders of hypersomnolence and immune-based disorders.

Neurology 2017 Jan 18;88(1):93-100. Epub 2016 Nov 18.

From the National Reference Centre for Orphan Diseases, Narcolepsy, Idiopathic Hypersomnia and Kleine-Levin Syndrome (L.B., R.L., I.A., M.L., P.F., S.L.-S., Y.D.), Paris; Clinical Neurophysiology Department (X.D), CHU de Poitiers; Inserm, U1061 (L.B., R.L., I.J., Y.D.), Montpellier; Université de Montpellier (L.B., R.L., I.J., Y.D.); Sleep Disorders Center, Department of Neurology (L.B., R.L., Y.D.), Gui-de-Chauliac Hospital, CHU Montpellier; Sleep Disorders Unit (I.A., S.L.-S.), Pitié-Salpêtrière University Hospital, AP-HP, Brain Research Institute (CRICM-UPMC-Paris 6; Inserm UMR-S 975; CNRS UMR 7225), Sorbonne University, UPMC Univ Paris 06; Pediatric Sleep Disorder Centre (M.L.), CHU Robert-Debré, AP-HP, Paris; and Pediatric Sleep Unit (P.F.), Hôpital Femme Mère Enfant, Integrative Physiology of Brain Arousal System, CRNL, INSERM-U1028, CNRS UMR5292, University Lyon 1, France.

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January 2017

Medulla oblongata damage and cardiac autonomic dysfunction in Parkinson disease.

Neurology 2016 Dec 11;87(24):2540-2545. Epub 2016 Nov 11.

From Centre de NeuroImagerie de Recherche-CENIR (N.P., M.M., R.V., L.Y-C., I.A., S.L.), Institut du Cerveau et de la Moelle Épinière (ICM), Paris; UPMC Univ Paris 06, UMR S 1127, CNRS UMR 7225, ICM, F-75013 (N.P., M.M., R.V., L.Y-C., E.D., M.V., I.A., S.L.), Sorbonne Universités; Service de Neuroradiologie (N.P., S.L.), Clinique des Mouvements Anormaux, Département des Maladies du Système Nerveux (C.E., M.V.), INSERM, Centre d'Investigation Clinique (CIC9503), Département des Maladies du Système Nerveux (M.V.), and Service des Pathologies du Sommeil (E.D., I.A.), Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière; and NeuroSpin (C.P.), Commissariat à l'Energie Atomique (CEA), Gif-Sur-Yvette, France.

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December 2016

Familial Kleine-Levin Syndrome: A Specific Entity?

Sleep 2016 Aug 1;39(8):1535-42. Epub 2016 Aug 1.

National Reference Center for Narcolepsy, Idiopathic Hypersomnia and Kleine-Levin Syndrome, Sleep Disorders Unit and Hospital-University Institute of Neuroscience, Pitié-Salpêtrière Hospital (APHP), Pierre and Marie Curie University, Paris, France.

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August 2016

The role of the melanoma gene MC1R in Parkinson disease and REM sleep behavior disorder.

Neurobiol Aging 2016 07 6;43:180.e7-180.e13. Epub 2016 Apr 6.

Montreal Neurological Institute, McGill University, Montréal, Quebec, Canada; Department of Human Genetics, McGill University, Montréal, Quebec, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec, Canada. Electronic address:

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July 2016

Sleepiness in sleepwalking and sleep terrors: a higher sleep pressure?

Sleep Med 2016 10 4;26:54-59. Epub 2016 Jan 4.

Sleep Disorders Unit of the Pitié-Salpêtrière University Hospital, APHP, Paris, France; Biostatistics Department of the Pitié-Salpêtrière University Hospital, APHP, Paris, France; Brain Research Institute (CRICM), INSERM UMR-S975, CNRS UMR7225, Paris, France. Electronic address:

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October 2016

The coeruleus/subcoeruleus complex in idiopathic rapid eye movement sleep behaviour disorder.

Brain 2016 Apr 26;139(Pt 4):1180-8. Epub 2016 Feb 26.

Sleep Disorders Unit, Pitié-Salpêtrière Hospital, AP-HP, Paris, France Sorbonne University, UPMC Paris-6, Paris, France Brain and Spine Institute - ICM, Centre for Neuroimaging Research - CENIR, UPMC UMR 1127; Inserm U 1127; CNRS UMR 7225, Team Control of Normal and Abnormal Movement, Paris, France INSERM AP-HP, CIC-1421, University Hospital, Paris, 75013, France

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April 2016

Does Postural Rigidity Decrease during REM Sleep without Atonia in Parkinson Disease?

J Clin Sleep Med 2016 06 15;12(6):839-47. Epub 2016 Jun 15.

APHP- Pitié-Salpêtrière Hospital, Sleep Disorders Unit, Paris, France.

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June 2016

Loss of REM sleep features across nighttime in REM sleep behavior disorder.

Sleep Med 2016 Jan 2;17:134-7. Epub 2015 Dec 2.

Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France. Electronic address:

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January 2016

Benefits and risk of sodium oxybate in idiopathic hypersomnia versus narcolepsy type 1: a chart review.

Sleep Med 2016 Jan 19;17:38-44. Epub 2015 Oct 19.

AP-HP, Hôpital Universitaire Pitié-Salpêtrière, Services des Pathologies du Sommeil, Paris, France; Centre National de Référence: Narcolepsie et Hypersomnie, Paris, France; Université Pierre et Marie Curie - Paris 6, Paris, France; Institut Hospitalo-Universitaire de Neuroscience, Université Pierre et Marie Curie - Paris 6, Paris, France. Electronic address:

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January 2016

Complex periodic limb movements during sleep or partial epileptic seizures?

Neurology 2015 Dec;85(24):2180

From the Epileptology Unit, Department of Neurology (V.-H.N.-M., O.S., V.L., S.D., C.A.), and the Sleep Disorders Unit, National Reference Center for Narcolepsy, Hypersomnia and Kleine-Levin Syndrome (I.A.), Pitié-Salpêtrière Hospital, Paris, France.

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December 2015

Smoking, Alcohol, Drug Use, Abuse and Dependence in Narcolepsy and Idiopathic Hypersomnia: A Case-Control Study.

Sleep 2016 Mar 1;39(3):573-80. Epub 2016 Mar 1.

Sleep Disorders Center, Department of Neurology, Gui-de-Chauliac Hospital, CHU Montpellier, France.

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March 2016

Sleep aspects on video-polysomnography in LRRK2 mutation carriers.

Mov Disord 2015 Nov 15;30(13):1839-43. Epub 2015 Oct 15.

AP-HP, Hôpital Pitié-Salpêtrière, Sleep Disorders unit and Neurology Department, F-75013, Paris, France.

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November 2015

Reply to Piano et al.

Sleep Med 2016 04 28;20:174-5. Epub 2015 Aug 28.

APHP, Sleep Disorder Unit, Pitié-Salpêtrière University Hospital, Paris, France; Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière - Université Pierre et Marie Curie-Paris 6, Inserm UMR_S 975, CNRS UMR 7225, France. Electronic address:

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April 2016

Lithium therapy in Kleine-Levin syndrome: An open-label, controlled study in 130 patients.

Neurology 2015 Nov 9;85(19):1655-62. Epub 2015 Oct 9.

From the Sleep Disorders Unit and National Reference Center for Narcolepsy, Hypersomnia and Kleine-Levin Syndrome (S.L.-S., T.L.C., E.G., S.L., I.A.), and Department of Biostatistics (J.-L.G.), Pitié-Salpêtrière University Hospital; AP-HP (S.L.-S., I.A.), Brain Research Institute (CRICM-UPMC-Paris 6; Inserm UMR_S 975; CNRS UMR 7225), Sorbonne Universities, UPMC Univ Paris 06; and AP-HP and ER4 (J.-L.G.), Pierre and Marie Curie University, Paris, France.

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November 2015

From state dissociation to status dissociatus.

Sleep Med Rev 2016 08 6;28:5-17. Epub 2015 Aug 6.

Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy; IRCCS Institute of Neurological Sciences, Bologna, Italy. Electronic address:

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August 2016

Long-Term Cognitive Impairment in Kleine-Levin Syndrome.

Sleep 2016 Feb 1;39(2):429-38. Epub 2016 Feb 1.

Sorbonne University, UPMC Univ Paris 06, IHU neuroscience, Reference Center for Kleine-Levin Syndrome of the Pitié-Salpêtrière University Hospital, Assistance Publique - Hôpitaux de Paris, France.

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February 2016

GBA mutations are associated with Rapid Eye Movement Sleep Behavior Disorder.

Ann Clin Transl Neurol 2015 Sep 31;2(9):941-5. Epub 2015 Jul 31.

Montreal Neurological Institute, McGill University Montréal, Quebec, Canada ; Department of Human Genetics, McGill University Montréal, Quebec, Canada ; Department of Neurology and Neurosurgery, McGill University Montréal, Quebec, Canada.

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September 2015

Sleep-Related Painful Erections in a Patient With Obstructive Sleep Apnea Syndrome.

Arch Sex Behav 2016 Jan 21;45(1):241-5. Epub 2015 Sep 21.

Sleep Disorders Unit, Pitié-Salpêtrière Hospital, Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière, Pierre and Marie Curie University, UMR_S 975-CNRS UMR 722, Paris, France.

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January 2016

Choking during sleep: can it be expression of arousal disorder?

Sleep Med 2015 Nov 29;16(11):1441-1447. Epub 2015 May 29.

Sleep Disorders Unit, Chest and Sleep Department, Hôpital Pitié-Salpêtrière, APHP, Paris, France; Centre de Recherche de l'Institut du Cerveau et de la Moelle Épinière, INSERM U 1127-CNRS UMR 722, Université Pierre et Marie Curie-Paris 6, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, F-75013 Paris, France. Electronic address:

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November 2015

Evidence that non-dreamers do dream: a REM sleep behaviour disorder model.

J Sleep Res 2015 Dec 25;24(6):602-9. Epub 2015 Aug 25.

Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, APHP, Paris, France.

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December 2015

Cortical Drive to Breathe during Wakefulness in Patients with Obstructive Sleep Apnea Syndrome.

Sleep 2015 Nov 1;38(11):1743-9. Epub 2015 Nov 1.

Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158 "Neurophysiologie Respiratoire Expérimentale et Clinique", Paris, France.

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November 2015

Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms in Pediatric Narcolepsy: A Cross-Sectional Study.

Sleep 2015 Aug 1;38(8):1285-95. Epub 2015 Aug 1.

National Reference Centre for Orphan Diseases, Narcolepsy, Idiopathic hypersomnia and Kleine-Levin Syndrome, France.

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August 2015

Serum cytokine levels in Kleine-Levin syndrome.

Sleep Med 2015 Aug 15;16(8):961-5. Epub 2015 May 15.

Center for Sleep Sciences and Medicine, Department of Psychiatry and Behavioral Studies, Stanford School of Medicine, Palo Alto, CA, USA.

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August 2015

Kleine-Levin Syndrome.

Authors:
Isabelle Arnulf

Sleep Med Clin 2015 Jun;10(2):151-61

Sleep Disorder Unit, National Reference Center for Narcolepsy, Idiopathic Hypersomnia and Kleine Levin syndrome, Inserm U975, Pitié-Salpêtrière Hospital (APHP), Paris 6 University, Paris, France. Electronic address:

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June 2015

Car Crashes and Central Disorders of Hypersomnolence: A French Study.

PLoS One 2015 8;10(6):e0129386. Epub 2015 Jun 8.

Sleep Disorders Center, Department of Neurology, Gui-de-Chauliac Hospital, CHU Montpellier, Montpellier, France; Inserm U1061, Montpellier, France, Université Montpellier 1, Montpellier, France; National Reference Centre for Orphan Diseases, Narcolepsy, Idiopathic hypersomnia and Kleine-Levin Syndrome (CNR narcolepsie-hypersomnie), Paris, France.

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February 2016

Status dissociatus and disturbed dreaming in a patient with Morvan syndrome plus myasthenia gravis.

Sleep Med 2015 Jul 21;16(7):894-6. Epub 2015 Apr 21.

Sleep Disorders Unit, APHP, Pitié-Salpêtrière Hospital, Paris, France; CRICM, Inserm U975-CNRS, Pierre and Marie Curie University (Sorbonne Universities, Univ Paris 6), Paris, France. Electronic address:

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July 2015

Characterization of the painful restless legs syndrome.

Sleep Med 2015 Jul 28;16(7):897. Epub 2015 Apr 28.

Sleep Disorder Unit, Pitié-Salpêtrière University Hospital, Paris, France; Pierre and Marie Curie University, Paris, France; Brain and Spinal Cord Research Institute (CRICM)-UPMC/Inserm U1127/CNRS UMR7225, Paris, France. Electronic address:

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July 2015

Nocturnal agitation in Huntington disease is caused by arousal-related abnormal movements rather than by rapid eye movement sleep behavior disorder.

Sleep Med 2015 Jun 3;16(6):754-9. Epub 2015 Mar 3.

APHP, Sleep Disorder Unit, Pitié-Salpêtrière University Hospital, Paris, France; Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière, INSERM UMR_S 975, CNRS UMR 7225, Université Pierre et Marie Curie, Paris 6, Paris, France. Electronic address:

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June 2015

Impact of cytokine in type 1 narcolepsy: Role of pandemic H1N1 vaccination ?

J Autoimmun 2015 Jun 16;60:20-31. Epub 2015 Apr 16.

National Reference Centre for Orphan Diseases, Narcolepsy, Idiopathic Hypersomnia and Kleine-Levin Syndrome (CNR narcolepsie-hypersomnie), France; Inserm U1061, Montpellier, France; Université Montpellier 1, Montpellier, France; Sleep Disorders Center, Department of Neurology, Gui-de-Chauliac Hospital, CHU Montpellier, France. Electronic address:

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June 2015