Publications by authors named "Isabella Spinello"

8Publications

Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells.

Authors:
Ernestina Saulle Isabella Spinello Maria Teresa Quaranta Luca Pasquini Elvira Pelosi Egidio Iorio Germana Castelli Mattea Chirico Maria Elena Pisanu Tiziana Ottone Maria Teresa Voso Ugo Testa Catherine Labbaye

Front Oncol 2020 5;10:621458. Epub 2021 Feb 5.

National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.

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February 2021

The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells.

Authors:
Isabella Spinello Ernestina Saulle Maria Teresa Quaranta Luca Pasquini Elvira Pelosi Germana Castelli Tiziana Ottone Maria Teresa Voso Ugo Testa Catherine Labbaye

Haematologica 2019 05 22;104(5):973-985. Epub 2018 Nov 22.

National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome

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May 2019

Identification of β-Dystrobrevin as a Direct Target of miR-143: Involvement in Early Stages of Neural Differentiation.

Authors:
Maria Teresa Quaranta Isabella Spinello Rosa Paolillo Gianfranco Macchia Alessandra Boe Marina Ceccarini Catherine Labbaye Pompeo Macioce

PLoS One 2016 25;11(5):e0156325. Epub 2016 May 25.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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July 2017

Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy.

Authors:
Isabella Spinello Maria Teresa Quaranta Rosa Paolillo Elvira Pelosi Anna Maria Cerio Ernestina Saulle Francesco Lo Coco Ugo Testa Catherine Labbaye

Haematologica 2015 Sep 4;100(9):1160-71. Epub 2015 Jun 4.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, University of Rome "Tor Vergata", Rome, Italy

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September 2015

Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells.

Authors:
Rosa Paolillo Isabella Spinello Maria Teresa Quaranta Luca Pasquini Elvira Pelosi Francesco Lo Coco Ugo Testa Catherine Labbaye

PLoS One 2015 11;10(5):e0126968. Epub 2015 May 11.

Department of Hematology, Oncology and Molecular Medicine of Istituto Superiore di Sanità, 00161, Rome, Italy.

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April 2016

miR-146a controls CXCR4 expression in a pathway that involves PLZF and can be used to inhibit HIV-1 infection of CD4(+) T lymphocytes.

Authors:
Maria Teresa Quaranta Eleonora Olivetta Massimo Sanchez Isabella Spinello Rosa Paolillo Claudia Arenaccio Maurizio Federico Catherine Labbaye

Virology 2015 Apr 21;478:27-38. Epub 2015 Feb 21.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. Electronic address:

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April 2015

Autocrine role of angiopoietins during megakaryocytic differentiation.

Authors:
Ernestina Saulle Raffaella Guerriero Alessia Petronelli Elena Coppotelli Marco Gabbianelli Ornella Morsilli Isabella Spinello Elvira Pelosi Germana Castelli Ugo Testa Simona Coppola

PLoS One 2012 6;7(7):e39796. Epub 2012 Jul 6.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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March 2013

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis.

Authors:
Catherine Labbaye Isabella Spinello Maria Teresa Quaranta Elvira Pelosi Luca Pasquini Eleonora Petrucci Mauro Biffoni Eugenia Rosa Nuzzolo Monia Billi Robin Foà Ercole Brunetti Francesco Grignani Ugo Testa Cesare Peschle

Nat Cell Biol 2008 Jul 22;10(7):788-801. Epub 2008 Jun 22.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.

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July 2008