Publications by authors named "Isabella Manni"

39Publications

Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of hedgehog-dependent medulloblastoma.

Cancer Lett 2020 Nov 26. Epub 2020 Nov 26.

Department of Molecular Medicine, University La Sapienza, Roma, Italy; Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Molecular Medicine, University La Sapienza, Roma, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2020.11.028DOI Listing
November 2020

Uncovering the expression patterns and the clinical significance of miR-182, miR-205, miR-27a and miR-369 in patients with urinary bladder cancer.

Mol Biol Rep 2020 Nov 31;47(11):8819-8830. Epub 2020 Oct 31.

Laboratory of proteins engineering and bioactive molecules (LIP-MB), INSAT, University of Tunis Carthage, Tunis, Tunisia.

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http://dx.doi.org/10.1007/s11033-020-05932-3DOI Listing
November 2020

Diabetes promotes invasive pancreatic cancer by increasing systemic and tumour carbonyl stress in Kras mice.

J Exp Clin Cancer Res 2020 Aug 10;39(1):152. Epub 2020 Aug 10.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Via di Grottarossa, 1035-1039 -, 00189, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-020-01665-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418209PMC
August 2020

Transgenic Animal Models to Visualize Cancer-Related Cellular Processes by Bioluminescence Imaging.

Front Pharmacol 2019 15;10:235. Epub 2019 Mar 15.

UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, IRCCS-Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.3389/fphar.2019.00235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428995PMC
March 2019

Radiolabeling of VEGF165 with 99mTc to evaluate VEGFR expression in tumor angiogenesis.

Int J Oncol 2017 Jun 8;50(6):2171-2179. Epub 2017 May 8.

Nuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, 'Sapienza' University of Rome, Rome, Italy.

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http://dx.doi.org/10.3892/ijo.2017.3989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903896PMC
June 2017

Monitoring the Response of Hyperbilirubinemia in the Mouse Brain by In Vivo Bioluminescence Imaging.

Int J Mol Sci 2016 Dec 28;18(1). Epub 2016 Dec 28.

Department of Research, Advanced Diagnostic, and Technological Innovation, Regina Elena National Cancer Institute, 00144 Rome, Italy.

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http://dx.doi.org/10.3390/ijms18010050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297685PMC
December 2016

NF-Y in cancer: Impact on cell transformation of a gene essential for proliferation.

Biochim Biophys Acta Gene Regul Mech 2017 May 9;1860(5):604-616. Epub 2016 Dec 9.

Department of Research, Advanced Diagnostics and Technological Innovation, UOSD SAFU, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2016.12.005DOI Listing
May 2017

Infinity: An In-Silico Tool for Genome-Wide Prediction of Specific DNA Matrices in miRNA Genomic Loci.

PLoS One 2016 15;11(4):e0153658. Epub 2016 Apr 15.

Department of Research, Advanced Diagnostics, and Technological Innovation, Regina Elena National Cancer Institute, Rome, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153658PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833383PMC
September 2016

Bioluminescence imaging of estrogen receptor activity during breast cancer progression.

Am J Nucl Med Mol Imaging 2016 28;6(1):32-41. Epub 2016 Jan 28.

Department of Pharmacological and Biomolecular Sciences, Center of Excellence on Neurodegenerative Diseases, University of Milan 20133, Milan, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749503PMC
April 2016

A bioluminescent mouse model of proliferation to highlight early stages of pancreatic cancer: A suitable tool for preclinical studies.

Ann Anat 2016 Sep 15;207:2-8. Epub 2015 Dec 15.

Department of Research, Advanced Diagnostics and Technological Innovation, Regina Elena National Cancer Institute, Via Elio Chianesi 53, Rome 00144, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.aanat.2015.11.010DOI Listing
September 2016

In Vivo Imaging of Natural Killer Cell Trafficking in Tumors.

J Nucl Med 2015 Oct 13;56(10):1575-80. Epub 2015 Aug 13.

Nuclear Medicine Unit, Faculty of Medicine and Psychology, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University, Rome, Italy Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.2967/jnumed.114.152918DOI Listing
October 2015

ATM kinase sustains HER2 tumorigenicity in breast cancer.

Nat Commun 2015 Apr 16;6:6886. Epub 2015 Apr 16.

1] Laboratory of Cell Signaling, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, 00179 Rome, Italy [2] Department of Biology, University of Rome 'Tor Vergata', 00133 Rome, Italy.

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http://dx.doi.org/10.1038/ncomms7886DOI Listing
April 2015

In vivo imaging of cell proliferation for a dynamic, whole body, analysis of undesired drug effects.

Toxicol Sci 2015 Jun 12;145(2):296-306. Epub 2015 Mar 12.

*Center of Excellence on Neurodegenerative Diseases and Department of Pharmacological Sciences, University of Milan, 20133 Milan, Italy; Experimental Oncology Department, Istituto Regina Elena, 00158 Rome, Italy

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http://dx.doi.org/10.1093/toxsci/kfv056DOI Listing
June 2015

(99m)Tc-labeled-rhTSH analogue (TR1401) for imaging poorly differentiated metastatic thyroid cancer.

Thyroid 2014 Aug 20;24(8):1297-308. Epub 2014 Jun 20.

1 Nuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, "Sapienza" University of Rome , Rome, Italy .

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http://dx.doi.org/10.1089/thy.2013.0429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106381PMC
August 2014

Immunotherapy in new pre-clinical models of HPV-associated oral cancers.

Hum Vaccin Immunother 2013 Mar 7;9(3):534-43. Epub 2013 Jan 7.

Laboratory of Virology; Regina Elena National Cancer Institute; Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891709PMC
http://dx.doi.org/10.4161/hv.23232DOI Listing
March 2013

The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms.

FASEB J 2009 Nov 16;23(11):3957-66. Epub 2009 Jul 16.

Experimental Oncology Department, Istituto Regina Elena, Via delle Messi D'Oro 156, 00158 Rome, Italy.

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http://www.fasebj.org/content/23/11/3957.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.09-131847
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http://dx.doi.org/10.1096/fj.09-131847DOI Listing
November 2009

Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity.

Mol Biol Cell 2008 Dec 24;19(12):5203-13. Epub 2008 Sep 24.

Molecular Oncogenesis Laboratory, Regina Elena Cancer Institute, 00158 Rome, Italy.

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http://www.molbiolcell.org/doi/10.1091/mbc.e08-03-0295
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http://dx.doi.org/10.1091/mbc.e08-03-0295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592644PMC
December 2008

Cell cycle regulation of NF-YC nuclear localization.

Cell Cycle 2004 Feb;3(2):217-22

Dipartimento di Biologia Animale; Universita di Modena e Reggio Emilia, Modena, Italy.

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February 2004

YB-1 as a cell cycle-regulated transcription factor facilitating cyclin A and cyclin B1 gene expression.

J Biol Chem 2003 Jul 14;278(30):27988-96. Epub 2003 Apr 14.

Max-Delbrück-Centrum für Molekulare Medizin, Robert-Rössle-Strasse 10, 13092 Berlin, Germany.

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http://dx.doi.org/10.1074/jbc.M212966200DOI Listing
July 2003