Publications by authors named "Isabel Varela-Nieto"

74Publications

G6PD overexpression protects from oxidative stress and age-related hearing loss.

Aging Cell 2020 12 22;19(12):e13275. Epub 2020 Nov 22.

Institute for Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM, Madrid, Spain.

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December 2020

Otic Neurogenesis Is Regulated by TGFβ in a Senescence-Independent Manner.

Front Cell Neurosci 2020 17;14:217. Epub 2020 Aug 17.

Institute for Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM), Madrid, Spain.

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August 2020

Drug development for noise-induced hearing loss.

Expert Opin Drug Discov 2020 Dec 25;15(12):1457-1471. Epub 2020 Aug 25.

Institute for Biomedical Research "Alberto Sols" CSIC-UAM , Madrid, Spain.

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December 2020

Solid Lipid Nanoparticles Loaded with Glucocorticoids Protect Auditory Cells from Cisplatin-Induced Ototoxicity.

J Clin Med 2019 Sep 14;8(9). Epub 2019 Sep 14.

Institute for Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM), 28029 Madrid, Spain.

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September 2019

TGFβ2-induced senescence during early inner ear development.

Sci Rep 2019 04 11;9(1):5912. Epub 2019 Apr 11.

Instituto de Investigaciones Biomédicas "Alberto Sols" (CSIC-UAM), Madrid, Spain.

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April 2019

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.

Elife 2019 04 2;8. Epub 2019 Apr 2.

Institute for Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM), Madrid, Spain.

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April 2019

Neuroglial Involvement in Abnormal Glutamate Transport in the Cochlear Nuclei of the Mouse.

Front Cell Neurosci 2019 1;13:67. Epub 2019 Mar 1.

Grupo de Neurobiología de la Audición, Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.

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March 2019

Complementary and distinct roles of autophagy, apoptosis and senescence during early inner ear development.

Hear Res 2019 05 23;376:86-96. Epub 2019 Jan 23.

Institute for Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM), Madrid, Spain; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Madrid, Spain; Biology Department, Faculty of Sciences, Autonomous University of Madrid (UAM), Madrid, Spain. Electronic address:

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May 2019

Editorial: Hormones and Neural Aging: Lessons From Experimental Models.

Front Aging Neurosci 2018 15;10:374. Epub 2018 Nov 15.

Instituto Cajal, CSIC and Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto Carlos III, Madrid, Spain.

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November 2018

Modelling physical resilience in ageing mice.

Mech Ageing Dev 2019 01 2;177:91-102. Epub 2018 Oct 2.

MRC/Arthritis Research-UK Centre for Integrated Research into Musculoskeletal Ageing (CIMA), Department of Oncology and Metabolism, The Medical School, Beech Hill Road, Sheffield, S10 2RX, United Kingdom. Electronic address:

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January 2019

MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse.

Am J Hum Genet 2018 07 28;103(1):74-88. Epub 2018 Jun 28.

Hearing and Genes Division, Department of Otorhinolaryngology, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands. Electronic address:

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July 2018

The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss.

Front Aging Neurosci 2017 12;9:411. Epub 2017 Dec 12.

"Alberto Sols" Biomedical Research Institute CSIC-UAM, Madrid, Spain.

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December 2017

The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea.

Hear Res 2018 02 14;358:10-21. Epub 2017 Dec 14.

Príncipe de Asturias University Hospital, Universidad de Alcalá, Carretera Alcalá-Meco s/n, 28805, Alcalá de Henares, Madrid, Spain; Institute of Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM), Arturo Duperier 4, 28029, Madrid, Spain; Centre for Biomedical Network Research in Rare Diseases (CIBERER), Institute of Health Carlos III (ISCIII), Monforte de Lemos, 3-5, 28029, Madrid, Spain. Electronic address:

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February 2018

Usefulness of Electrical Auditory Brainstem Responses to Assess the Functionality of the Cochlear Nerve Using an Intracochlear Test Electrode.

Otol Neurotol 2017 12;38(10):e413-e420

*Department of Otolaryngology, "La Paz" University Hospital †Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-U761) ‡Instituto de Investigación Hospital Universitario La Paz (IdiPAZ), Madrid, Spain §Med-El Corporation, Insbruck, Austria ||Instituto de Investigaciones Biomédicas "Alberto Sols" CSIC-UAM, Madrid, Spain.

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December 2017

Autophagy in the Vertebrate Inner Ear.

Front Cell Dev Biol 2017 26;5:56. Epub 2017 May 26.

Department of Endocrine and Nervous Systems Pathophysiology, Instituto de Investigaciones Biomédicas "Alberto Sols," CSIC-UAMMadrid, Spain.

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May 2017