Isabel Alves

Isabel Alves

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Isabel Alves

Isabel Alves

Publications by authors named "Isabel Alves"

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Putative interaction site for membrane phospholipids controls activation of TRPA1 channel at physiological membrane potentials.

FEBS J 2019 Sep 6;286(18):3664-3683. Epub 2019 Jun 6.

Department of Cellular Neurophysiology, Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

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http://dx.doi.org/10.1111/febs.14931DOI Listing
September 2019

Biophysical Insight on the Membrane Insertion of an Arginine-Rich Cell-Penetrating Peptide.

Int J Mol Sci 2019 Sep 9;20(18). Epub 2019 Sep 9.

Institute of Chemistry & Biology of Membranes & Nanoobjects (CBMN), CNRS UMR5248, University of Bordeaux, Bordeaux INP, allée Geoffroy St-Hilaire, 33600 Pessac, France.

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http://dx.doi.org/10.3390/ijms20184441DOI Listing
September 2019

Microfluidic smartphone quantitation of Escherichia coli in synthetic urine.

Biosens Bioelectron 2019 Sep 6;145:111624. Epub 2019 Sep 6.

Centre for Biosensors, Bioelectronics and Biodevices (C3Bio), Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2019.111624DOI Listing
September 2019

The Contribution of Differential Scanning Calorimetry for the Study of Peptide/Lipid Interactions.

Methods Mol Biol 2019 ;1964:3-15

Chimie et Biologie des Membranes et Nanoobjets, CBMN CNRS UMR 5248, Université Bordeaux 1, Pessac, France.

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http://dx.doi.org/10.1007/978-1-4939-9179-2_1DOI Listing
August 2019

Structural insights into the AapA1 toxin of Helicobacter pylori.

Biochim Biophys Acta Gen Subj 2019 Aug 30:129423. Epub 2019 Aug 30.

INSERM, U1212, CNRS UMR 5320, Univ. Bordeaux, Laboratoire ARNA, F-33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2019.129423DOI Listing
August 2019

Study of G-Protein Coupled Receptor Signaling in Membrane Environment by Plasmon Waveguide Resonance.

Acc Chem Res 2019 Apr 13;52(4):1059-1067. Epub 2019 Mar 13.

CBMN UMR 5248 CNRS, University of Bordeaux, Bat. B14 allée Geoffroy St. Hilaire , 33600 Pessac , France.

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http://dx.doi.org/10.1021/acs.accounts.9b00007DOI Listing
April 2019

Improved Detection of Plasmon Waveguide Resonance Using Diverging Beam, Liquid Crystal Retarder, and Application to Lipid Orientation Determination.

Sensors (Basel) 2019 Mar 21;19(6). Epub 2019 Mar 21.

Department of Electrooptics and Photonics Engineering and The Ilse Katz Institute for Nanoscale Science and Technology, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.

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http://dx.doi.org/10.3390/s19061402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471420PMC
March 2019

Immunocapture of Escherichia coli in a fluoropolymer microcapillary array.

J Chromatogr A 2019 Jan 24;1585:46-55. Epub 2018 Nov 24.

Department of Chemical Engineering, Loughborough University, Leicestershire LE11 3TU, UK; Department of Chemical Engineering, Claverton Down, University of Bath, Bath BA2 7AY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2018.11.067DOI Listing
January 2019

The impact of recombination on human mutation load and disease.

Philos Trans R Soc Lond B Biol Sci 2017 Dec;372(1736)

Ontario Institute of Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, Canada M5G 0A3.

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http://dx.doi.org/10.1098/rstb.2016.0465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698626PMC
December 2017

Exploiting Benzophenone Photoreactivity To Probe the Phospholipid Environment and Insertion Depth of the Cell-Penetrating Peptide Penetratin in Model Membranes.

Angew Chem Int Ed Engl 2017 07 6;56(28):8226-8230. Epub 2017 Jun 6.

Department of Chemistry, Sorbonne Universités, UPMC Univ Paris 06, PSL Research University, Ecole Normale Supérieure, CNRS, Laboratoire des Biomolécules (LBM), 4 place Jussieu, 75005, Paris, France.

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http://dx.doi.org/10.1002/anie.201703465DOI Listing
July 2017

Real time monitoring of membrane GPCR reconstitution by plasmon waveguide resonance: on the role of lipids.

Sci Rep 2016 11 8;6:36181. Epub 2016 Nov 8.

Chemistry and Biology of Membranes and Nanoobjects, UMR 5248 CNRS, University of Bordeaux, Bat. B14 allée Geoffroy St. Hilaire, 33600 Pessac, France.

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http://dx.doi.org/10.1038/srep36181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099921PMC
November 2016

A genomic history of Aboriginal Australia.

Nature 2016 Oct 21;538(7624):207-214. Epub 2016 Sep 21.

Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.

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http://dx.doi.org/10.1038/nature18299DOI Listing
October 2016

A Pathway Toward Tumor Cell-Selective CPPs?

Methods Mol Biol 2015 ;1324:279-301

Institute of Chemistry & Biology of Membranes & Nanoobjects (UMR5248 CBMN), CNRS, Institut Polytechnique Bordeaux, Universite Bordeaux, All. Geoffroy Saint-Hilaire, 33600, Pessac, France,

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http://dx.doi.org/10.1007/978-1-4939-2806-4_18DOI Listing
April 2016

Long-Distance Dispersal Shaped Patterns of Human Genetic Diversity in Eurasia.

Mol Biol Evol 2016 Apr 4;33(4):946-58. Epub 2015 Dec 4.

Computational and Molecular Population Genetics Lab, Institute of Ecology and Evolution, University of Bern, Bern, Switzerland Swiss Institute of Bioinformatics, Lausanne, Switzerland

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http://dx.doi.org/10.1093/molbev/msv332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776706PMC
April 2016

Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane.

Biochim Biophys Acta 2015 May 14;1848(5):1147-56. Epub 2015 Feb 14.

CBMN-UMR 5248 CNRS, University of Bordeaux, IPB, Allée Geoffroy St. Hilaire, 33600 Pessac, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2015.02.003DOI Listing
May 2015

Plasmon waveguide resonance for sensing glycan-lectin interactions.

Anal Chim Acta 2015 May 24;873:71-9. Epub 2015 Feb 24.

Institute of Electronics, Microelectronics and Nanotechnology (IEMN),UMR-CNRS 8520, Université Lille 1, Cité Scientifique, 59655 Villeneuve d'Ascq, France. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2015.02.060DOI Listing
May 2015

Interaction of Aβ(1-42) amyloids with lipids promotes "off-pathway" oligomerization and membrane damage.

Biomacromolecules 2015 Mar 26;16(3):944-50. Epub 2015 Feb 26.

Chimie et Biologie des Membranes et Nanoobjets, CBMN CNRS UMR 5248, Université de Bordeaux , Allée Geoffroy de Saint Hilaire, 33600 Pessac, France.

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http://dx.doi.org/10.1021/bm501837wDOI Listing
March 2015

The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides.

Biochim Biophys Acta 2015 Feb 20;1848(2):593-602. Epub 2014 Nov 20.

CBMN-Univ Bordeaux, UMR 5248, Allée Geoffroy St Hilaire, 33600 Pessac, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2014.11.013DOI Listing
February 2015

On the importance of electrostatic interactions between cell penetrating peptides and membranes: a pathway toward tumor cell selectivity?

Biochimie 2014 Dec 5;107 Pt A:154-9. Epub 2014 Aug 5.

CBMN-Univ Bordeaux, UMR 5248, Allée Geoffroy St Hilaire, 33600 Pessac, France. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2014.07.022DOI Listing
December 2014

A peptide derived from the rotavirus outer capsid protein VP7 permeabilizes artificial membranes.

Biochim Biophys Acta 2014 Aug 15;1838(8):2026-35. Epub 2014 Apr 15.

LCRB, CNRS (UMR 8015), Université Paris Descartes, F-75270 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2014.04.005DOI Listing
August 2014

A proapoptotic peptide conjugated to penetratin selectively inhibits tumor cell growth.

Biochim Biophys Acta 2014 Aug 2;1838(8):2087-98. Epub 2014 May 2.

Sorbonne Universités, UPMC Univ Paris 6, Laboratoire des BioMolécules, 4 place Jussieu, CNRS UMR 7203 and ENS, LBM, Dpt de Chimie, 24, Rue Lhomond, 75005 Paris. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2014.04.025DOI Listing
August 2014

Endoscopic gastric band removal: safe and effective alternative to surgery.

Dig Endosc 2014 May 17;26(3):495-6. Epub 2014 Mar 17.

Department of Gastroenterology, São Francisco Xavier Hospital, Occidental Lisbon Hospital Center, Lisbon, Portugal.

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http://dx.doi.org/10.1111/den.12267DOI Listing
May 2014

Treatment of gastric metastases from renal cell carcinoma with endoscopic therapy.

Clin J Gastroenterol 2014 Apr 8;7(2):148-54. Epub 2014 Mar 8.

Department of Gastroenterology, Egas Moniz Hospital, Ocidental Lisbon Hospitalar Center, Rua da Junqueira 126, 1349-019, Lisbon, Portugal,

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http://link.springer.com/content/pdf/10.1007%2Fs12328-014-04
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http://link.springer.com/10.1007/s12328-014-0470-x
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http://dx.doi.org/10.1007/s12328-014-0470-xDOI Listing
April 2014

Rubber particle proteins, HbREF and HbSRPP, show different interactions with model membranes.

Biochim Biophys Acta 2014 Jan 12;1838(1 Pt B):287-99. Epub 2013 Sep 12.

CNRS, LCPO, UMR 5629, F-33600 Pessac, France; Univ. Bordeaux, LCPO, UMR 5629, F-33600 Pessac, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2013.08.025DOI Listing
January 2014

Homeoproteins and homeoprotein-derived peptides: going in and out.

Curr Pharm Des 2013 ;19(16):2851-62

UPMC Univ Paris 6, Laboratoire des BioMolécules, Labex MiChem, Sorbonne University, 4 place Jussieu, F-75005 Paris, France.

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http://dx.doi.org/10.2174/1381612811319160002DOI Listing
October 2013

Direct translocation of cell-penetrating peptides in liposomes: a combined mass spectrometry quantification and fluorescence detection study.

Anal Biochem 2013 Jul 20;438(1):1-10. Epub 2013 Mar 20.

UMR 7203 CNRS, ENS, Laboratoire des Biomolécules, UPMC-Université Paris 06, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.ab.2013.03.009DOI Listing
July 2013

Tryptophan within basic peptide sequences triggers glycosaminoglycan-dependent endocytosis.

FASEB J 2013 Feb 15;27(2):738-49. Epub 2012 Oct 15.

Université Pierre et Marie Curie, Université Paris 6, Unité Mixte de Recherche 7203, Paris, France.

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http://dx.doi.org/10.1096/fj.12-216176DOI Listing
February 2013

Structure and dynamics of the two amphipathic arginine-rich peptides RW9 and RL9 in a lipid environment investigated by solid-state NMR and MD simulations.

Biochim Biophys Acta 2013 Feb 19;1828(2):824-33. Epub 2012 Nov 19.

Institute for Medical Physics and Biophysics, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1016/j.bbamem.2012.11.014DOI Listing
February 2013

Genomic data reveal a complex making of humans.

PLoS Genet 2012 19;8(7):e1002837. Epub 2012 Jul 19.

CMPG, Institute of Ecology and Evolution, Berne, Switzerland.

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http://dx.doi.org/10.1371/journal.pgen.1002837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400556PMC
January 2013

The timing of pigmentation lightening in Europeans.

Mol Biol Evol 2013 Jan 25;30(1):24-35. Epub 2012 Aug 25.

IPATIMUP, Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1093/molbev/mss207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525146PMC
January 2013

Is there anybody in there? On the mechanisms of wall crossing of cell penetrating peptides.

Curr Protein Pept Sci 2012 Nov;13(7):658-71

CBMN-UMR 5248 CNRS, Université de Bordeaux, IPB, Pessac, France.

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November 2012

Membrane-active peptides: mechanisms of action.

Authors:
Isabel D Alves

Curr Protein Pept Sci 2012 Nov;13(7):601

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November 2012

A yeast toxic mutant of HET-s amyloid disrupts membrane integrity.

Biochim Biophys Acta 2012 Sep 27;1818(9):2325-34. Epub 2012 Apr 27.

Université Bordeaux 1, Allée Geoffroy de Saint Hilaire, Pessac, France.

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http://dx.doi.org/10.1016/j.bbamem.2012.04.013DOI Listing
September 2012

Membrane interactions of two arginine-rich peptides with different cell internalization capacities.

Biochim Biophys Acta 2012 Jul;1818(7):1755-63

UPMC-Paris 06, UMR 7203 CNRS, ENS, Laboratoire des BioMolecules, 4, place jussieu, Paris F-75005, France.

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http://dx.doi.org/10.1016/j.bbamem.2012.02.024DOI Listing
July 2012

The interaction of antipsychotic drugs with lipids and subsequent lipid reorganization investigated using biophysical methods.

Biochim Biophys Acta 2011 Aug 4;1808(8):2009-18. Epub 2011 Mar 4.

Université Pierre et Marie Curie-Paris 6, UMRS 7203 CNRS-ENS, Laboratoire des BioMolécules, 4, place Jussieu, 75252 Paris cedex 05, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00052736110006
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http://dx.doi.org/10.1016/j.bbamem.2011.02.021DOI Listing
August 2011

Genetic homogeneity across Bantu-speaking groups from Mozambique and Angola challenges early split scenarios between East and West Bantu populations.

Hum Biol 2011 Feb;83(1):13-38

IPATIMUP, Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Portugal.

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http://dx.doi.org/10.3378/027.083.0102DOI Listing
February 2011

Cell biology meets biophysics to unveil the different mechanisms of penetratin internalization in cells.

Biochim Biophys Acta 2010 Dec 10;1798(12):2231-9. Epub 2010 Feb 10.

Université Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1016/j.bbamem.2010.02.009DOI Listing
December 2010

NMR structure of a viral peptide inserted in artificial membranes: a view on the early steps of the birnavirus entry process.

J Biol Chem 2010 Jun 9;285(25):19409-21. Epub 2010 Apr 9.

Unité de Pharmacologie Chimique et Génétique, CNRS, UMR 8151, Faculté des Sciences Pharmaceutiques et Biologiques, Université Paris Descartes, 4 Avenue de l'Observatoire, Paris F-75270 Cedex 06, France.

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http://dx.doi.org/10.1074/jbc.M109.076083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885221PMC
June 2010

Comparing lipid photo-cross-linking efficacy of penetratin analogues bearing three different photoprobes: dithienyl ketone, benzophenone, and trifluoromethylaryldiazirine.

Bioconjug Chem 2010 Feb;21(2):352-9

UPMC Paris 06 - ENS - CNRS, UMR 7203, Laboratoire des BioMolecules, FR 2769 Chimie Moleculaire, Universite Pierre et Marie Curie, Case courier 182, 4, Place Jussieu, 75252 Paris Cedex 05, France.

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http://pubs.acs.org/doi/abs/10.1021/bc900466q
Publisher Site
http://dx.doi.org/10.1021/bc900466qDOI Listing
February 2010

Translocation and endocytosis for cell-penetrating peptide internalization.

J Biol Chem 2009 Dec 15;284(49):33957-65. Epub 2009 Oct 15.

Laboratoire des Biomolécules, Université Pierre et Marie Curie (Paris 6), 75005 Paris, France.

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http://dx.doi.org/10.1074/jbc.M109.056309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797166PMC
December 2009

The role of membranes in the organization of HIV-1 Gag p6 and Vpr: p6 shows high affinity for membrane bilayers which substantially increases the interaction between p6 and Vpr.

J Med Chem 2009 Nov;52(22):7157-62

Departement de Chimie, Ecole Normale Superieure, CNRS, UMR 8642, 24 rue Lhomond, 75231 Paris cedex 05, France.

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http://dx.doi.org/10.1021/jm901106tDOI Listing
November 2009

Lipid reorganization induced by membrane-active peptides probed using differential scanning calorimetry.

Biochim Biophys Acta 2009 Sep 7;1788(9):1772-81. Epub 2009 May 7.

UPMC Univ Paris 06, FRE 2852 Peptidome de la Peau d'Amphibiens, Paris F-75005, France.

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http://dx.doi.org/10.1016/j.bbamem.2009.05.001DOI Listing
September 2009

Chapter 6. Plasmon resonance methods in membrane protein biology applications to GPCR signaling.

Methods Enzymol 2009 ;461:123-46

Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, Arizona, USA.

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http://dx.doi.org/10.1016/S0076-6879(09)05406-8DOI Listing
August 2009

Structural studies of HIV-1 Gag p6ct and its interaction with Vpr determined by solution nuclear magnetic resonance.

Biochemistry 2009 Mar;48(11):2355-67

Unité de Pharmacologie Chimique et Génétique, Inserm U640, CNRS UMR8151, UFR des Sciences Pharmaceutiques et Biologiques, 4, avenue de l'Observatoire, 75270 Paris Cedex 06, France.

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http://dx.doi.org/10.1021/bi801794vDOI Listing
March 2009

Membrane interaction and perturbation mechanisms induced by two cationic cell penetrating peptides with distinct charge distribution.

Biochim Biophys Acta 2008 Jul-Aug;1780(7-8):948-59. Epub 2008 May 2.

UPMC Univ Paris 06, UMR 7613 Synthèse, Structure et Fonction de Molécules Bioactives, FR 2769, Paris F-75005, France.

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http://dx.doi.org/10.1016/j.bbagen.2008.04.004DOI Listing
July 2008

Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.

Mol Pharmacol 2007 May 22;71(5):1416-26. Epub 2007 Feb 22.

Department of Medical Pharmacology, The University of Arizona, Tucson, AZ 85724, USA.

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http://dx.doi.org/10.1124/mol.106.030023DOI Listing
May 2007

Analysis of an intact G-protein coupled receptor by MALDI-TOF mass spectrometry: molecular heterogeneity of the tachykinin NK-1 receptor.

Anal Chem 2007 Mar 13;79(6):2189-98. Epub 2007 Feb 13.

Synthèse, Structure et Fonction de Molécules Bioactives, and Plateforme de Protéomique et de Spectrométrie de Masse, Université Pierre et Marie Curie-Paris 6, UMR 7613 CNRS, Paris, France. alves@ ccr.jussieu.fr

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http://dx.doi.org/10.1021/ac062415uDOI Listing
March 2007

Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers.

J Am Chem Soc 2005 Apr;127(15):5435-48

The Carl S. Marvel Laboratories, Department of Chemistry, The University of Arizona, 1306 East University Blvd., Tucson, Arizona 85721, USA.

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http://dx.doi.org/10.1021/ja0432158DOI Listing
April 2005

Plasmon-waveguide resonance studies of lateral segregation of lipids and proteins into microdomains (rafts) in solid-supported bilayers.

J Biol Chem 2005 Mar 24;280(12):11175-84. Epub 2005 Jan 24.

Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, Arizona 85721, USA.

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http://dx.doi.org/10.1074/jbc.M411197200DOI Listing
March 2005

Selectivity, cooperativity, and reciprocity in the interactions between the delta-opioid receptor, its ligands, and G-proteins.

J Biol Chem 2004 Oct 17;279(43):44673-82. Epub 2004 Aug 17.

Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson 85721, USA.

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http://dx.doi.org/10.1074/jbc.M404713200DOI Listing
October 2004

Successful treatment of cutaneous leishmaniasis with lipid formulations of amphotericin B in two immunocompromised patients.

Acta Trop 2004 Oct;92(2):127-32

Infectious and Parasitic Diseases Clinic, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, Avenida Dr. Enéas de Carvalho Aguiar 255, São Paulo, Brazil.

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http://dx.doi.org/10.1016/j.actatropica.2004.06.006DOI Listing
October 2004

Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.

Biochem J 2004 Jul;381(Pt 2):351-6

Molecular Neurobiology Unit, Instituto de Biologia Molecular e Celular e Departamento de Biologia Molecular, ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1042/BJ20040011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133839PMC
July 2004

A novel 3-step enantioselective synthesis of pyrenylalanine with subsequent incorporation into opioid, CCK, and melanotropin ligands.

Biochem Biophys Res Commun 2004 May;318(2):335-40

Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ 85721, USA.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.033DOI Listing
May 2004

Direct observation of G-protein binding to the human delta-opioid receptor using plasmon-waveguide resonance spectroscopy.

J Biol Chem 2003 Dec 30;278(49):48890-7. Epub 2003 Sep 30.

Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, Arizona 85721, USA.

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http://dx.doi.org/10.1074/jbc.M306866200DOI Listing
December 2003