Isaac Kinde

Isaac Kinde

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Isaac Kinde

Isaac Kinde

Publications by authors named "Isaac Kinde"

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30Publications

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Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing.

Proc Natl Acad Sci U S A 2016 08 15;113(35):9846-51. Epub 2016 Aug 15.

Ludwig Center for Cancer Genetics and Therapeutics, Department of Oncology, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21231.

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http://dx.doi.org/10.1073/pnas.1607794113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024639PMC
August 2016

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer.

Sci Transl Med 2016 07;8(346):346ra92

Division of Systems Biology and Personalised Medicine, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia. Department of Medical Oncology, Western Health, St Albans, Victoria 3021, Australia. Department of Medical Oncology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria 3010, Australia. Ludwig Institute for Cancer Research, New York, NY 10017, USA.

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http://stm.sciencemag.org/content/8/346/346ra92.full.pdf
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http://dx.doi.org/10.1126/scitranslmed.aaf6219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346159PMC
July 2016

Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study.

J Clin Oncol 2015 Dec 9;33(36):4293-300. Epub 2015 Nov 9.

Elisabeth Maritschnegg, Nina Pecha, Reinhard Horvat, Paul Speiser, and Robert Zeillinger, Medical University of Vienna, Vienna, Austria; Yuxuan Wang, Isaac Kinde, Luis A. Diaz Jr, Nickolas Papadopoulos, Kenneth W. Kinzler, and Bert Vogelstein, Johns Hopkins University, Baltimore, MD; Els Van Nieuwenhuysen and Ignace Vergote, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium; Florian Heitz, Kliniken Essen Mitte, Essen; and Jalid Sehouli, Charité Medical University, Berlin, Germany.

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http://dx.doi.org/10.1200/JCO.2015.61.3083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678180PMC
December 2015

A combination of molecular markers and clinical features improve the classification of pancreatic cysts.

Gastroenterology 2015 Nov 4;149(6):1501-10. Epub 2015 Aug 4.

The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, Baltimore, Maryland; Department of Surgery, The Johns Hopkins University, Baltimore, Maryland; Department of Medicine, The Johns Hopkins University, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.07.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782782PMC
November 2015

Detection of somatic TP53 mutations in tampons of patients with high-grade serous ovarian cancer.

Obstet Gynecol 2014 Nov;124(5):881-5

Departments of Obstetrics and Gynecology and Pathology, University of Alabama at Birmingham, Birmingham, Alabama; the Ludwig Center of Cancer Genetics and Therapeutics and the Swim Across America Laboratory at Johns Hopkins University, Baltimore, Maryland; and the Departments of Obstetrics and Gynecology and Pathology, University of Virginia, Charlottesville, Virginia.

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http://dx.doi.org/10.1097/AOG.0000000000000484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316672PMC
November 2014

Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas.

Genes Chromosomes Cancer 2014 Jan 5;53(1):15-24. Epub 2013 Nov 5.

Ludwig Center, the Howard Hughes Medical Institutions, and the Departmentof Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287.

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http://dx.doi.org/10.1002/gcc.22114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007004PMC
January 2014

Association of the autoimmune disease scleroderma with an immunologic response to cancer.

Science 2014 Jan 5;343(6167):152-7. Epub 2013 Dec 5.

Ludwig Center, the Howard Hughes Medical Institutions, and the Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1126/science.1246886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038033PMC
January 2014

TERT promoter mutations occur early in urothelial neoplasia and are biomarkers of early disease and disease recurrence in urine.

Cancer Res 2013 Dec 11;73(24):7162-7. Epub 2013 Oct 11.

Authors' Affiliations: The Ludwig Center for Cancer Genetics and Therapeutics, The Swim Across America Laboratory at Johns Hopkins, and The Howard Hughes Medical Institute at Johns Hopkins Kimmel Cancer Center; Departments of Pathology, Oncology, and Urology, The Johns Hopkins Medical Institutes, Baltimore, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966102PMC
December 2013

FAST-SeqS: a simple and efficient method for the detection of aneuploidy by massively parallel sequencing.

PLoS One 2012 18;7(7):e41162. Epub 2012 Jul 18.

The Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041162PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399813PMC
January 2013

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers.

Nature 2012 Jun;486(7404):537-40

Ludwig Center for Cancer Genetics and Therapeutics, Howard Hughes Medical Institute at Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1038/nature11219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436069PMC
June 2012

Detection and quantification of rare mutations with massively parallel sequencing.

Proc Natl Acad Sci U S A 2011 Jun 17;108(23):9530-5. Epub 2011 May 17.

The Ludwig Center for Cancer Genetics and Therapeutics and The Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1105422108
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http://dx.doi.org/10.1073/pnas.1105422108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111315PMC
June 2011

Development of personalized tumor biomarkers using massively parallel sequencing.

Sci Transl Med 2010 Feb;2(20):20ra14

Ludwig Center for Cancer Genetics and Therapeutics and Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1126/scitranslmed.3000702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858564PMC
February 2010

Entropic switch regulates myristate exposure in the HIV-1 matrix protein.

Proc Natl Acad Sci U S A 2004 Jan 29;101(2):517-22. Epub 2003 Dec 29.

Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250-5398, USA.

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http://dx.doi.org/10.1073/pnas.0305665101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC327179PMC
January 2004

Antiviral inhibition of the HIV-1 capsid protein.

J Mol Biol 2003 Apr;327(5):1013-20

Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250-5398, USA.

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http://dx.doi.org/10.1016/s0022-2836(03)00289-4DOI Listing
April 2003