Isaac J Nijman

Isaac J Nijman

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Isaac J Nijman

Isaac J Nijman

Publications by authors named "Isaac J Nijman"

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62Publications

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Amplicon-Based Targeted Next-Generation Sequencing of Formalin-Fixed, Paraffin-Embedded Tissue.

Methods Mol Biol 2019 ;1908:1-17

Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-9004-7_1DOI Listing
June 2019

Mice lacking functional CD95-ligand display reduced proliferation of the intestinal epithelium without gross homeostatic alterations.

Med Mol Morphol 2016 Jun 23;49(2):110-8. Epub 2015 Dec 23.

Department of Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00795-015-0129-9DOI Listing
June 2016

Genetic etiology of renal agenesis: fine mapping of Renag1 and identification of Kit as the candidate functional gene.

PLoS One 2015 18;10(2):e0118147. Epub 2015 Feb 18.

McArdle Laboratory for Cancer Research, Department of Oncology, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, United States of America; University of Wisconsin Carbone Cancer Center, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.

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http://edoc.mdc-berlin.de/14656/1/14656oa.pdf
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http://dx.plos.org/10.1371/journal.pone.0118147
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118147PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333340PMC
December 2015

Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia.

Am J Hum Genet 2015 Oct 17;97(4):621-6. Epub 2015 Sep 17.

Department of Medical Genetics, Centre for Molecular Medicine, University Medical Centre Utrecht, 3508 AB Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596913PMC
October 2015

Sambamba: fast processing of NGS alignment formats.

Bioinformatics 2015 Jun 19;31(12):2032-4. Epub 2015 Feb 19.

Department of Statistical Simulation, St. Petersburg State University, St. Petersburg, Russia, Illumina Cambridge, Cambridge, UK, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands, Department of Medical Genetics, Institute for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands and Department of Nematology, Wageningen University, Wageningen, The Netherlands Department of Statistical Simulation, St. Petersburg State University, St. Petersburg, Russia, Illumina Cambridge, Cambridge, UK, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands, Department of Medical Genetics, Institute for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands and Department of Nematology, Wageningen University, Wageningen, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/btv098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765878PMC
June 2015

Effective Therapeutic Intervention and Comprehensive Genetic Analysis of mTOR Signaling in PEComa: A Case Report.

Anticancer Res 2015 Jun;35(6):3399-403

Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.

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June 2015

Myeloid lineage-restricted somatic mosaicism of NLRP3 mutations in patients with variant Schnitzler syndrome.

J Allergy Clin Immunol 2015 Feb 16;135(2):561-4. Epub 2014 Sep 16.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, The Netherlands; Nijmegen Center for Immunodeficiency and Autoinflammation, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2014.07.050DOI Listing
February 2015

Simultaneous detection of clinically relevant mutations and amplifications for routine cancer pathology.

J Mol Diagn 2015 Jan 24;17(1):10-8. Epub 2014 Oct 24.

Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan Utrecht, Utrecht, the Netherlands; Netherlands Center for Personalized Cancer Treatment, Universiteitsweg Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.jmoldx.2014.09.004DOI Listing
January 2015

Effector identification in the lettuce downy mildew Bremia lactucae by massively parallel transcriptome sequencing.

Mol Plant Pathol 2012 Sep 1;13(7):719-31. Epub 2012 Feb 1.

Plant-Microbe Interactions, Department of Biology, Utrecht University, Padualaan 8, 3508 CH Utrecht, the Netherlands.

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http://dx.doi.org/10.1111/j.1364-3703.2011.00780.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638827PMC
September 2012

Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach.

BMC Genomics 2011 May 20;12:256. Epub 2011 May 20.

Hubrecht Institute, Developmental Biology and Stem Cell Research, KNAW and University Medical Center Utrecht, Uppsalalaan 8, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/1471-2164-12-256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114748PMC
May 2011

Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples.

Nat Methods 2010 Nov 17;7(11):913-5. Epub 2010 Oct 17.

Hubrecht Institute, Developmental Biology and Stem Cell Research, Royal Netherlands Academy of Arts and Sciences and the University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nmeth.1516DOI Listing
November 2010

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries.

Nucleic Acids Res 2010 Jun 17;38(10):e116. Epub 2010 Feb 17.

Hubrecht Institute and University Medical Center Utrecht, KNAW, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkq072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879533PMC
June 2010

Identification of genetic modifiers of behavioral phenotypes in serotonin transporter knockout rats.

BMC Genet 2010 May 7;11:37. Epub 2010 May 7.

Hubrecht Institute & University Medical Center Utrecht, Uppsalalaan 8, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/1471-2156-11-37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874760PMC
May 2010

Tracing the history of goat pastoralism: new clues from mitochondrial and Y chromosome DNA in North Africa.

Mol Biol Evol 2009 Dec 3;26(12):2765-73. Epub 2009 Sep 3.

Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1093/molbev/msp200DOI Listing
December 2009

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

BMC Genomics 2008 Oct 7;9:460. Epub 2008 Oct 7.

Hubrecht Institute for Developmental Biology and Stem Cell Research, Cancer Genomics Center, Royal Netherlands Academy of Sciences, Utrecht, The Netherlands.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-9-460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567347PMC
October 2008

Mismatch repair deficiency does not enhance ENU mutagenesis in the zebrafish germ line.

Mutagenesis 2008 Jul 9;23(4):325-9. Epub 2008 May 9.

Hubrecht Institute and Cancer Genomics Center, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/mutage/gen019DOI Listing
July 2008

Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors.

Cancer Res 2008 Jul;68(13):5059-66

Hubrecht Institute for Developmental Biology and Stem Cell Research, Cancer Genomics Center, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-0019DOI Listing
July 2008

A genome-wide SNP panel for mapping and association studies in the rat.

BMC Genomics 2008 Feb 25;9:95. Epub 2008 Feb 25.

Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/1471-2164-9-95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266910PMC
February 2008

Maternal and paternal lineages in cross-breeding bovine species. Has wisent a hybrid origin?

Mol Biol Evol 2004 Jul 22;21(7):1165-70. Epub 2004 Jan 22.

Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/molbev/msh064DOI Listing
July 2004

The phylogenetic position of the Theileria buffeli group in relation to other Theileria species.

Parasitol Res 2002 May;88(13 Suppl 1):S28-32

Division of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.

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http://dx.doi.org/10.1007/s00436-001-0566-3DOI Listing
May 2002

SINE retrotransposition during the evolution of the Pecoran ruminants.

J Mol Evol 2002 Jan;54(1):9-16

Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00239-001-0012-2DOI Listing
January 2002