Isaac B Hilton

Isaac B Hilton

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Isaac B Hilton

Isaac B Hilton

Publications by authors named "Isaac B Hilton"

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10Publications

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Genetic engineering: Chemical control for CRISPR editing.

Nat Chem Biol 2017 Jan 7;13(1):2-3. Epub 2016 Nov 7.

Department of Biomedical Engineering and the Center for Genomic &Computational Biology, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1038/nchembio.2243DOI Listing
January 2017

Editing the epigenome: technologies for programmable transcription and epigenetic modulation.

Nat Methods 2016 Feb;13(2):127-37

Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1038/nmeth.3733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922638PMC
February 2016

Enabling functional genomics with genome engineering.

Genome Res 2015 Oct;25(10):1442-55

Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA; Center for Genomic and Computational Biology, Duke University, Durham, North Carolina 27708, USA; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1101/gr.190124.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579329PMC
October 2015

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.

Nat Biotechnol 2015 May 6;33(5):510-7. Epub 2015 Apr 6.

1] Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA. [2] Center for Genomic &Computational Biology, Duke University, Durham, North Carolina, USA. [3] Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, USA.

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http://www.nature.com/articles/nbt.3199
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http://dx.doi.org/10.1038/nbt.3199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430400PMC
May 2015

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector.

Nucleic Acids Res 2014 Oct 13;42(19):e147. Epub 2014 Aug 13.

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA

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http://dx.doi.org/10.1093/nar/gku749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231726PMC
October 2014

The open chromatin landscape of Kaposi's sarcoma-associated herpesvirus.

J Virol 2013 Nov 28;87(21):11831-42. Epub 2013 Aug 28.

Lineberger Comprehensive Cancer Center.

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http://dx.doi.org/10.1128/JVI.01685-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807352PMC
November 2013

Quantitative analysis of the bidirectional viral G-protein-coupled receptor and lytic latency-associated nuclear antigen promoter of Kaposi's sarcoma-associated herpesvirus.

J Virol 2012 Sep 27;86(18):9683-95. Epub 2012 Jun 27.

Curriculum in Genetics and Molecular Biology, Comprehensive Cancer Center, Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1128/JVI.00881-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446609PMC
September 2012

Distinct p53, p53:LANA, and LANA complexes in Kaposi's Sarcoma--associated Herpesvirus Lymphomas.

J Virol 2010 Apr 3;84(8):3898-908. Epub 2010 Feb 3.

Department of Microbiology and Immunology, Lineberger Comprehensive Cancer Center, Center for AIDS Research, University of North Carolina at Chapel Hill, CB no. 7290, 715 Mary Ellen Jones Bldg., Chapel Hill, NC 27599-7290, USA.

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http://dx.doi.org/10.1128/JVI.01321-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849491PMC
April 2010