Irving L Weissman

Irving L Weissman

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Irving L Weissman

Irving L Weissman

Publications by authors named "Irving L Weissman"

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De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.

Nat Biotechnol 2019 Oct 19;37(10):1137-1144. Epub 2019 Aug 19.

Department of Surgery, Division of Cardiothoracic Surgery, Transplant and Stem Cell Immunobiology Lab, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/s41587-019-0227-7DOI Listing
October 2019

Phagocytosis checkpoints as new targets for cancer immunotherapy.

Nat Rev Cancer 2019 Oct 28;19(10):568-586. Epub 2019 Aug 28.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41568-019-0183-zDOI Listing
October 2019

The GABA receptor GABRR1 is expressed on and functional in hematopoietic stem cells and megakaryocyte progenitors.

Proc Natl Acad Sci U S A 2019 Sep 26;116(37):18416-18422. Epub 2019 Aug 26.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1906251116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744911PMC
September 2019

Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance.

Cell Stem Cell 2019 Aug 13;25(2):185-192.e3. Epub 2019 Jun 13.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Developmental Biology and the Stanford-UC Berkeley Stem Cell Institute, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679784PMC
August 2019

CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.

Nature 2019 Aug 31;572(7769):392-396. Epub 2019 Jul 31.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.

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http://www.nature.com/articles/s41586-019-1456-0
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http://dx.doi.org/10.1038/s41586-019-1456-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697206PMC
August 2019

Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes.

Development 2019 Aug 1;146(15). Epub 2019 Aug 1.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1242/dev.170571DOI Listing
August 2019

CD47-Targeted Near-Infrared Photoimmunotherapy for Human Bladder Cancer.

Clin Cancer Res 2019 Jun 19;25(12):3561-3571. Epub 2019 Mar 19.

Department of Urology, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-3267DOI Listing
June 2019

Regenerating the field of cardiovascular cell therapy.

Nat Biotechnol 2019 03 18;37(3):232-237. Epub 2019 Feb 18.

Institute for Stem Cell Biology and Regenerative Medicine; Ludwig Center for Cancer Stem Cell Biology and Medicine; Departments of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA.

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http://www.nature.com/articles/s41587-019-0042-1
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http://dx.doi.org/10.1038/s41587-019-0042-1DOI Listing
March 2019

Wounds Inhibit Tumor Growth In Vivo.

Ann Surg 2019 Feb 27. Epub 2019 Feb 27.

Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA.

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http://dx.doi.org/10.1097/SLA.0000000000003255DOI Listing
February 2019

Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo.

Proc Natl Acad Sci U S A 2019 01 8;116(4):1447-1456. Epub 2019 Jan 8.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1801480116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347684PMC
January 2019

CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma.

N Engl J Med 2018 Nov;379(18):1711-1721

From Stanford University, Stanford (R.A., T.T., R.M., I.L.W.), City of Hope, Duarte (L.P.), and Forty Seven, Menlo Park (J.L., J.Y.C., J.-P.V., B.A., J.H., R.M., I.L.W., C.H.T., M.P.C.) - all in California; Sarah Cannon Research Institute-Tennessee Oncology, Nashville (I.F.); University of Alabama at Birmingham, Birmingham (A.F.); Washington University in St. Louis, St. Louis (N.L.B.); Levine Cancer Institute-Atrium Health, Charlotte, NC (N.G.); University of Chicago, Chicago (J.K., S.M.S.); National Cancer Institute, Rockville, MD (M.R.); Dana-Farber Cancer Institute, Boston (A.L.); and University of Oxford, Oxford, United Kingdom (G.P.C.).

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http://dx.doi.org/10.1056/NEJMoa1807315DOI Listing
November 2018

Screening for genes that regulate the differentiation of human megakaryocytic lineage cells.

Proc Natl Acad Sci U S A 2018 10 27;115(40):E9308-E9316. Epub 2018 Aug 27.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1805434115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176640PMC
October 2018

Where Hematopoietic Stem Cells Live: The Bone Marrow Niche.

Antioxid Redox Signal 2018 07 9;29(2):191-204. Epub 2018 Jan 9.

1 Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine , Stanford, California.

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http://dx.doi.org/10.1089/ars.2017.7419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016729PMC
July 2018

HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice.

Dis Model Mech 2018 07 30;11(7). Epub 2018 Jul 30.

Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), 77 Cheong Am-Ro, Nam-Gu, Pohang, Gyeongbuk 37673, South Korea

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http://dx.doi.org/10.1242/dmm.033241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078398PMC
July 2018

Isolation and functional assessment of mouse skeletal stem cell lineage.

Nat Protoc 2018 06 10;13(6):1294-1309. Epub 2018 May 10.

Stanford Stem Cell Biology and Regenerative Medicine Institute, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1038/nprot.2018.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530903PMC
June 2018

Partial Lobular Hepatectomy: A Surgical Model for Morphologic Liver Regeneration.

J Vis Exp 2018 05 31(135). Epub 2018 May 31.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München; German Center for Lung Research (DZL);

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http://dx.doi.org/10.3791/57302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101439PMC
May 2018

Computational correction of index switching in multiplexed sequencing libraries.

Nat Methods 2018 04;15(5):305-307

Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/nmeth.4666DOI Listing
April 2018

Improving immune-vascular crosstalk for cancer immunotherapy.

Nat Rev Immunol 2018 03 15;18(3):195-203. Epub 2018 Jan 15.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nri.2017.145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922422PMC
March 2018

Normal and Neoplastic Stem Cells.

Cold Spring Harb Symp Quant Biol 2016 17;81:1-9. Epub 2017 Apr 17.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305.

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http://dx.doi.org/10.1101/sqb.2016.81.030965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766001PMC
February 2018

Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.

Proc Natl Acad Sci U S A 2017 12 20;114(49):E10578-E10585. Epub 2017 Nov 20.

Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research, Stanford University School of Medicine, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1710877114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724266PMC
December 2017

Hypoxia-inducible factor-1α regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice.

Oncotarget 2017 Dec 1;8(67):111508-111521. Epub 2017 Dec 1.

Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea.

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http://dx.doi.org/10.18632/oncotarget.22851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762339PMC
December 2017

Lessons from immuno-oncology: a new era for cancer nanomedicine?

Nat Rev Drug Discov 2017 Jun 17;16(6):369-370. Epub 2017 Mar 17.

Department of Neurosurgery, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, Florida 32224, USA.

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http://dx.doi.org/10.1038/nrd.2017.34DOI Listing
June 2017

Unifying mechanism for different fibrotic diseases.

Proc Natl Acad Sci U S A 2017 05 19;114(18):4757-4762. Epub 2017 Apr 19.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1621375114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422830PMC
May 2017

Identification of mouse cochlear progenitors that develop hair and supporting cells in the organ of Corti.

Nat Commun 2017 05 11;8:15046. Epub 2017 May 11.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/ncomms15046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437288PMC
May 2017

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.

Nature 2017 05 17;545(7655):495-499. Epub 2017 May 17.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature22396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931375PMC
May 2017

Localized hepatic lobular regeneration by central-vein-associated lineage-restricted progenitors.

Proc Natl Acad Sci U S A 2017 04 22;114(14):3654-3659. Epub 2017 Mar 22.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München, 81377 Munich, Germany;

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http://dx.doi.org/10.1073/pnas.1621361114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389277PMC
April 2017

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer.

Nat Commun 2017 04 5;8:14802. Epub 2017 Apr 5.

Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/ncomms14802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382276PMC
April 2017

Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.

Cell 2017 03;168(6):1041-1052.e18

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University School of Medicine, 299 Campus Drive, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526607PMC
March 2017

Breaking Down the Barriers to Precision Cancer Nanomedicine.

Trends Biotechnol 2017 02 1;35(2):159-171. Epub 2016 Aug 1.

Department of Neurosurgery, Mayo Clinic College of Medicine, Jacksonville, FL, USA; Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA; Department of Cancer Biology, Mayo Clinic College of Medicine, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2016.07.006DOI Listing
February 2017

Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate.

Nat Commun 2017 02 22;8:14533. Epub 2017 Feb 22.

Lund University, Medical Faculty, Institution for Laboratory Medicine, Division of Molecular Hematology, Klinikgatan 26, BMC B12, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1038/ncomms14533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322498PMC
February 2017

Age-associated changes in human hematopoietic stem cells.

Semin Hematol 2017 01 20;54(1):39-42. Epub 2016 Oct 20.

Institute for Stem Cell Biology and Regenerative Medicine, Ludwig Center for Stem Cell Research, Stanford University, Stanford, CA; Department of Pathology, Stanford University, Stanford, CA.

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http://dx.doi.org/10.1053/j.seminhematol.2016.10.004DOI Listing
January 2017

The Role of Efferocytosis in Atherosclerosis.

Circulation 2017 01;135(5):476-489

From Department of Surgery, Division of Vascular Surgery (Y.K., N.J.L.), Institute for Stem Cell Biology and Regenerative Medicine (I.L.W.), and Department of Medicine, Division of Cardiovascular Medicine (N.J.L.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.025684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302553PMC
January 2017

An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development.

Sci Data 2016 12 20;3:160109. Epub 2016 Dec 20.

Department of Developmental Biology, Institute for Stem Cell Biology and Regenerative Medicine, Ludwig Center for Cancer Stem Cell Biology and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/sdata.2016.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170597PMC
December 2016

Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos.

Cell Stem Cell 2016 11;19(5):587-592

Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo 108-8639, Japan; Institute for Stem Cell Biology and Regenerative Medicine, Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.10.013DOI Listing
November 2016

LYVE1 Marks the Divergence of Yolk Sac Definitive Hemogenic Endothelium from the Primitive Erythroid Lineage.

Cell Rep 2016 11;17(9):2286-2298

Department of Molecular, Cell & Developmental Biology, UCLA, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.080DOI Listing
November 2016

Immune Priming of the Tumor Microenvironment by Radiation.

Trends Cancer 2016 11 15;2(11):638-645. Epub 2016 Oct 15.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.trecan.2016.09.007DOI Listing
November 2016

Antibody Therapy Targeting CD47 and CD271 Effectively Suppresses Melanoma Metastasis in Patient-Derived Xenografts.

Cell Rep 2016 08 28;16(6):1701-1716. Epub 2016 Jul 28.

Department of Molecular Biology and Biochemistry, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92627, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.004DOI Listing
August 2016

Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy.

Sci Transl Med 2016 08;8(351):351ra105

Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA 94305, USA. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://stm.sciencemag.org/content/scitransmed/8/351/351ra105
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http://eknygos.lsmuni.lt/springer/351/201-217.pdf
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http://dx.doi.org/10.1126/scitranslmed.aae0501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668627PMC
August 2016

CIRM and UKRMP: Different Ways to Invest in Regenerative Medicine.

Cell Stem Cell 2016 07;19(1):19-22

King's College London Centre for Stem Cells and Regenerative Medicine, Floor 28, Tower Wing, Guy's Hospital Campus, Great Maze Pond, London SE1 9RT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.05.011DOI Listing
July 2016

Developmental cell death programs license cytotoxic cells to eliminate histocompatible partners.

Proc Natl Acad Sci U S A 2016 Jun 23;113(23):6520-5. Epub 2016 May 23.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Department of Pathology, Hopkins Marine Station, Stanford University, Pacific Grove, CA 93950; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1606276113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988592PMC
June 2016

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential.

PLoS One 2015 21;10(9):e0137345. Epub 2015 Sep 21.

Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137345PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577081PMC
May 2016

Identification of human erythroid lineage-committed progenitors.

Rinsho Ketsueki 2016 05;57(5):585-91

Department of Medicine and Biosystemic Science, Kyushu University Faculty of Medicine.

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http://dx.doi.org/10.11406/rinketsu.57.585DOI Listing
May 2016

Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors.

Proc Natl Acad Sci U S A 2016 Apr 31;113(16):4464-9. Epub 2016 Mar 31.

Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University, Stanford, CA 94305; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305

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https://www.nanets.net/nanets_cd/2015/pdfs/B4.pdf
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http://www.pnas.org/lookup/doi/10.1073/pnas.1600007113
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http://dx.doi.org/10.1073/pnas.1600007113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843455PMC
April 2016

Dynamic Patterns of Clonal Evolution in Tumor Vasculature Underlie Alterations in Lymphocyte-Endothelial Recognition to Foster Tumor Immune Escape.

Cancer Res 2016 Mar 30;76(6):1348-53. Epub 2015 Dec 30.

Stanford Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California. Departments of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794394PMC
March 2016

Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche.

Nature 2016 Feb;530(7589):223-7

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature16943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854608PMC
February 2016

A Mechanism for Somatic Brain Mosaicism.

Cell 2016 Feb;164(4):593-5

The Salk Institute for Biological Studies, Laboratory of Genetics, La Jolla, CA 92037, USA. Electronic address:

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http://www.cell.com/cell/pdf/S0092-8674(16)30062-9.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S009286741630062
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http://dx.doi.org/10.1016/j.cell.2016.01.048DOI Listing
February 2016

Evidence that β7 Integrin Regulates Hematopoietic Stem Cell Homing and Engraftment Through Interaction with MAdCAM-1.

Stem Cells Dev 2016 Jan 5;25(1):18-26. Epub 2015 Nov 5.

1 Division of Hematopoietic Stem Cell and Leukemia Research, Beckman Research Institute of City of Hope , Duarte, California.

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https://www.liebertpub.com/doi/10.1089/scd.2014.0551
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http://dx.doi.org/10.1089/scd.2014.0551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692116PMC
January 2016

Surveillance of Stem Cell Fate and Function: A System for Assessing Cell Survival and Collagen Expression In Situ.

Tissue Eng Part A 2016 Jan 24;22(1-2):31-40. Epub 2015 Dec 24.

1 Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine , Stanford, California.

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http://dx.doi.org/10.1089/ten.TEA.2015.0221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741228PMC
January 2016

Macrophages are critical effectors of antibody therapies for cancer.

MAbs 2015 ;7(2):303-10

a Institute for Stem Cell Biology and Regenerative Medicine ; Stanford University School of Medicine ; Stanford , CA USA.

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http://dx.doi.org/10.1080/19420862.2015.1011450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622600PMC
November 2015

Neural Placode Tissue Derived From Myelomeningocele Repair Serves as a Viable Source of Oligodendrocyte Progenitor Cells.

Neurosurgery 2015 Nov;77(5):794-802; discussion 802

‡Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California; §Department of Neurosurgery, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, California; ¶Department of Neurosurgery, VA Palo Alto Health Care System, Stanford University School of Medicine, Palo Alto, California; ∥Department of Neurological Surgery, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1227/NEU.0000000000000918DOI Listing
November 2015

Lift NIH restrictions on chimera research.

Science 2015 Nov 5;350(6261):640. Epub 2015 Nov 5.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1126/science.350.6261.640-aDOI Listing
November 2015

Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging.

Proc Natl Acad Sci U S A 2015 Nov 10;112(47):E6506-14. Epub 2015 Nov 10.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA 94305; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305; Department of Pathology, Stanford University Medical Center, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1519623112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664306PMC
November 2015

Sleep disruption impairs haematopoietic stem cell transplantation in mice.

Nat Commun 2015 Oct 14;6:8516. Epub 2015 Oct 14.

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/ncomms9516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621781PMC
October 2015

Expression of TCR-Vβ peptides by murine bone marrow cells does not identify T-cell progenitors.

J Cell Mol Med 2015 Aug 6;19(8):1956-64. Epub 2015 Mar 6.

Research School of Biology, Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.1111/jcmm.12572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549046PMC
August 2015

Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 "Don't Eat Me" Signals.

Clin Cancer Res 2015 Aug 26;21(16):3597-601. Epub 2015 Jun 26.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California. Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California. Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California. Department of Pathology, Stanford University Medical Center, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621226PMC
August 2015

Prospective isolation of human erythroid lineage-committed progenitors.

Proc Natl Acad Sci U S A 2015 Aug 20;112(31):9638-43. Epub 2015 Jul 20.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Biology and Medicine at Stanford University, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1512076112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534255PMC
August 2015

Identification and characterization of an injury-induced skeletal progenitor.

Proc Natl Acad Sci U S A 2015 Aug 27;112(32):9920-5. Epub 2015 Jul 27.

Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305-5148; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1513066112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538608PMC
August 2015

fibroblasts and melanoma.

Melanoma Manag 2015 Aug 10;2(3):191-192. Epub 2015 Aug 10.

Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Plastic & Reconstructive Surgery, Stanford University School of Medicine, Stanford, CA, USA.

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https://www.futuremedicine.com/doi/10.2217/mmt.15.23
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http://dx.doi.org/10.2217/mmt.15.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094637PMC
August 2015

Stem cells are units of natural selection for tissue formation, for germline development, and in cancer development.

Proc Natl Acad Sci U S A 2015 Jul;112(29):8922-8

Institute for Stem Cell Biology and Regenerative Medicine and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University; and Stanford University School of Medicine, Stanford, CA 94305-5461

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http://www.pnas.org/lookup/doi/10.1073/pnas.1505464112
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http://dx.doi.org/10.1073/pnas.1505464112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517284PMC
July 2015

CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer.

Proc Natl Acad Sci U S A 2015 Apr 30;112(15):4725-30. Epub 2015 Mar 30.

Institute of Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1424795112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403197PMC
April 2015

Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential.

Science 2015 Apr;348(6232):aaa2151

Institute for Stem Cell Biology and Regenerative Medicine, Departments of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088503PMC
http://dx.doi.org/10.1126/science.aaa2151DOI Listing
April 2015

Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.

Cell 2015 Mar 26;160(6):1196-208. Epub 2015 Feb 26.

Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766813PMC
March 2015

Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk.

Proc Natl Acad Sci U S A 2015 Feb 2;112(7):2145-50. Epub 2015 Feb 2.

Institute for Stem Cell Biology and Regenerative Medicine, Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford Cancer Institute, and Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1424907112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343163PMC
February 2015

SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts.

Cell Stem Cell 2015 Jan 20;16(1):33-8. Epub 2014 Nov 20.

TSI Laboratory, University Heart Center Hamburg, Martinistrasse 52, 20246 Hamburg, Germany; Cardiovascular Research Center Hamburg (CVRC) and DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Luebeck, Martinistrasse 52, 20246 Hamburg, Germany; Stanford Cardiovascular Institute and Department of Cardiothoracic Surgery, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.11.003DOI Listing
January 2015

Identification and specification of the mouse skeletal stem cell.

Cell 2015 Jan;160(1-2):285-98

Department of Surgery, Stanford University, 450 Serra Mall, Palo Alto, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 450 Serra Mall, Palo Alto, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297645PMC
January 2015

, an emerging model for the study of aging, stem cells, and mechanisms of regeneration.

Invertebr Reprod Dev 2015 Jan 9;59(sup1):33-38. Epub 2014 Dec 9.

Department of Pathology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, and Hopkins Marine Station , Stanford , CA , USA ; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine , Stanford , CA , USA.

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http://dx.doi.org/10.1080/07924259.2014.944673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464096PMC
January 2015