Publications by authors named "Iros Barozzi"

52Publications

Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.

Authors:
David U Gorkin Iros Barozzi Yuan Zhao Yanxiao Zhang Hui Huang Ah Young Lee Bin Li Joshua Chiou Andre Wildberg Bo Ding Bo Zhang Mengchi Wang J Seth Strattan Jean M Davidson Yunjiang Qiu Veena Afzal Jennifer A Akiyama Ingrid Plajzer-Frick Catherine S Novak Momoe Kato Tyler H Garvin Quan T Pham Anne N Harrington Brandon J Mannion Elizabeth A Lee Yoko Fukuda-Yuzawa Yupeng He Sebastian Preissl Sora Chee Jee Yun Han Brian A Williams Diane Trout Henry Amrhein Hongbo Yang J Michael Cherry Wei Wang Kyle Gaulton Joseph R Ecker Yin Shen Diane E Dickel Axel Visel Len A Pennacchio Bing Ren

Nature 2021 Jan;589(7842):E4

Ludwig Institute for Cancer Research, La Jolla, CA, USA.

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January 2021

Phenotypic mapping of pathological crosstalk between glioblastoma and innate immune cells by synthetic genetic tracing.

Authors:
Matthias Jürgen Schmitt Carlos Company Yuliia Dramaretska Iros Barozzi Andreas Göhrig Sonia Kertalli Melanie Großmann Heike Naumann Maria Pilar Sanchez-Bailon Danielle Hulsman Rainer Glass Massimo Squatrito Michela Serresi Gaetano Gargiulo

Cancer Discov 2020 Dec 23. Epub 2020 Dec 23.

Cancer Research, Max Delbrück Center for Molecular Medicine

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December 2020

Evolution of Advanced Chronic Lymphoid Leukemia Unveiled by Single-Cell Transcriptomics: A Case Report.

Authors:
Pavel Ostasov Henry Robertson Paolo Piazza Avik Datta Jane Apperley Lucie Houdova Daniel Lysak Monika Holubova Katerina Tesarova Valentina S Caputo Iros Barozzi

Front Oncol 2020 30;10:584607. Epub 2020 Oct 30.

Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

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October 2020

Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.

Authors:
David U Gorkin Iros Barozzi Yuan Zhao Yanxiao Zhang Hui Huang Ah Young Lee Bin Li Joshua Chiou Andre Wildberg Bo Ding Bo Zhang Mengchi Wang J Seth Strattan Jean M Davidson Yunjiang Qiu Veena Afzal Jennifer A Akiyama Ingrid Plajzer-Frick Catherine S Novak Momoe Kato Tyler H Garvin Quan T Pham Anne N Harrington Brandon J Mannion Elizabeth A Lee Yoko Fukuda-Yuzawa Yupeng He Sebastian Preissl Sora Chee Jee Yun Han Brian A Williams Diane Trout Henry Amrhein Hongbo Yang J Michael Cherry Wei Wang Kyle Gaulton Joseph R Ecker Yin Shen Diane E Dickel Axel Visel Len A Pennacchio Bing Ren

Nature 2020 Oct;586(7831):E31

Ludwig Institute for Cancer Research, La Jolla, CA, USA.

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October 2020

Supervised enhancer prediction with epigenetic pattern recognition and targeted validation.

Authors:
Anurag Sethi Mengting Gu Emrah Gumusgoz Landon Chan Koon-Kiu Yan Joel Rozowsky Iros Barozzi Veena Afzal Jennifer A Akiyama Ingrid Plajzer-Frick Chengfei Yan Catherine S Novak Momoe Kato Tyler H Garvin Quan Pham Anne Harrington Brandon J Mannion Elizabeth A Lee Yoko Fukuda-Yuzawa Axel Visel Diane E Dickel Kevin Y Yip Richard Sutton Len A Pennacchio Mark Gerstein

Nat Methods 2020 08 29;17(8):807-814. Epub 2020 Jul 29.

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.

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August 2020

An atlas of dynamic chromatin landscapes in mouse fetal development.

Authors:
David U Gorkin Iros Barozzi Yuan Zhao Yanxiao Zhang Hui Huang Ah Young Lee Bin Li Joshua Chiou Andre Wildberg Bo Ding Bo Zhang Mengchi Wang J Seth Strattan Jean M Davidson Yunjiang Qiu Veena Afzal Jennifer A Akiyama Ingrid Plajzer-Frick Catherine S Novak Momoe Kato Tyler H Garvin Quan T Pham Anne N Harrington Brandon J Mannion Elizabeth A Lee Yoko Fukuda-Yuzawa Yupeng He Sebastian Preissl Sora Chee Jee Yun Han Brian A Williams Diane Trout Henry Amrhein Hongbo Yang J Michael Cherry Wei Wang Kyle Gaulton Joseph R Ecker Yin Shen Diane E Dickel Axel Visel Len A Pennacchio Bing Ren

Nature 2020 07 29;583(7818):744-751. Epub 2020 Jul 29.

Ludwig Institute for Cancer Research, La Jolla, CA, USA.

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July 2020

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer.

Authors:
Ahmet Acar Daniel Nichol Javier Fernandez-Mateos George D Cresswell Iros Barozzi Sung Pil Hong Nicholas Trahearn Inmaculada Spiteri Mark Stubbs Rosemary Burke Adam Stewart Giulio Caravagna Benjamin Werner Georgios Vlachogiannis Carlo C Maley Luca Magnani Nicola Valeri Udai Banerji Andrea Sottoriva

Nat Commun 2020 04 21;11(1):1923. Epub 2020 Apr 21.

Evolutionary Genomics and Modelling Lab, Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.

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April 2020

Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation.

Authors:
Roberto Ravasio Elena Ceccacci Luciano Nicosia Amir Hosseini Pier Luigi Rossi Iros Barozzi Lorenzo Fornasari Roberto Dal Zuffo Sergio Valente Rossella Fioravanti Ciro Mercurio Mario Varasi Andrea Mattevi Antonello Mai Giulio Pavesi Tiziana Bonaldi Saverio Minucci

Sci Adv 2020 04 8;6(15):eaax2746. Epub 2020 Apr 8.

Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Via Adamello 16, Milan 20139, Italy.

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April 2020

High-resolution label-free 3D mapping of extracellular pH of single living cells.

Authors:
Yanjun Zhang Yasufumi Takahashi Sung Pil Hong Fengjie Liu Joanna Bednarska Philip S Goff Pavel Novak Andrew Shevchuk Sahana Gopal Iros Barozzi Luca Magnani Hideki Sakai Yoshimoto Suguru Takuto Fujii Alexander Erofeev Peter Gorelkin Alexander Majouga Dominik J Weiss Christopher Edwards Aleksandar P Ivanov David Klenerman Elena V Sviderskaya Joshua B Edel Yuri Korchev

Nat Commun 2019 12 6;10(1):5610. Epub 2019 Dec 6.

Department of Medicine, Imperial College London, London, W12 0NN, UK.

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December 2019

Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy.

Authors:
Sung Pil Hong Thalia E Chan Ylenia Lombardo Giacomo Corleone Nicole Rotmensz Sara Bravaccini Andrea Rocca Giancarlo Pruneri Kirsten R McEwen R Charles Coombes Iros Barozzi Luca Magnani

Nat Commun 2019 09 2;10(1):3840. Epub 2019 Sep 2.

Department of Surgery and Cancer, Imperial College London, London, UK.

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September 2019

Author Correction: Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion.

Authors:
Van T M Nguyen Iros Barozzi Monica Faronato Ylenia Lombardo Jennifer H Steel Naina Patel Philippa Darbre Leandro Castellano Balázs Győrffy Laura Woodley Alba Rodriguez-Meira Darren K Patten Valentina Vircillo Manikandan Periyasamy Simak Ali Gianmaria Frige Saverio Minucci R Charles Coombes Luca Magnani

Nat Commun 2019 Aug 6;10(1):3505. Epub 2019 Aug 6.

Department of Surgery and Cancer, Imperial College London, London, W12 0NN, UK.

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August 2019

Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells.

Authors:
Federico Comoglio Marta Simonatto Sara Polletti Xin Liu Stephen T Smale Iros Barozzi Gioacchino Natoli

Genes Dev 2019 09 1;33(17-18):1159-1174. Epub 2019 Aug 1.

Humanitas University (Hunimed), Pieve Emanuele, Milano 20090, Italy.

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September 2019

Noncoding deletions reveal a gene that is critical for intestinal function.

Authors:
Danit Oz-Levi Tsviya Olender Ifat Bar-Joseph Yiwen Zhu Dina Marek-Yagel Iros Barozzi Marco Osterwalder Anna Alkelai Elizabeth K Ruzzo Yujun Han Erica S M Vos Haike Reznik-Wolf Corina Hartman Raanan Shamir Batia Weiss Rivka Shapiro Ben Pode-Shakked Pavlo Tatarskyy Roni Milgrom Michael Schvimer Iris Barshack Denise M Imai Devin Coleman-Derr Diane E Dickel Alex S Nord Veena Afzal Kelly Lammerts van Bueren Ralston M Barnes Brian L Black Christopher N Mayhew Matthew F Kuhar Amy Pitstick Mehmet Tekman Horia C Stanescu James M Wells Robert Kleta Wouter de Laat David B Goldstein Elon Pras Axel Visel Doron Lancet Yair Anikster Len A Pennacchio

Nature 2019 07 19;571(7763):107-111. Epub 2019 Jun 19.

Division of Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.

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July 2019

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.

Authors:
Sergi Cuartero Felix D Weiss Gopuraja Dharmalingam Ya Guo Elizabeth Ing-Simmons Silvia Masella Irene Robles-Rebollo Xiaolin Xiao Yi-Fang Wang Iros Barozzi Dounia Djeghloul Mariane T Amano Henri Niskanen Enrico Petretto Robin D Dowell Kikuë Tachibana Minna U Kaikkonen Kim A Nasmyth Boris Lenhard Gioacchino Natoli Amanda G Fisher Matthias Merkenschlager

Nat Immunol 2018 09 20;19(9):932-941. Epub 2018 Aug 20.

Lymphocyte Development Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.

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September 2018

Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer.

Authors:
Darren K Patten Giacomo Corleone Balázs Győrffy Ylenia Perone Neil Slaven Iros Barozzi Edina Erdős Alina Saiakhova Kate Goddard Andrea Vingiani Sami Shousha Lőrinc Sándor Pongor Dimitri J Hadjiminas Gaia Schiavon Peter Barry Carlo Palmieri Raul C Coombes Peter Scacheri Giancarlo Pruneri Luca Magnani

Nat Med 2018 09 23;24(9):1469-1480. Epub 2018 Jul 23.

Department of Surgery and Cancer, The Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, UK.

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September 2018

Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures.

Authors:
Federico Comoglio Hyun Jung Park Stefan Schoenfelder Iros Barozzi Daniel Bode Peter Fraser Anthony R Green

Genome Res 2018 02 2. Epub 2018 Feb 2.

University of Cambridge.

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February 2018

Enhancer redundancy provides phenotypic robustness in mammalian development.

Authors:
Marco Osterwalder Iros Barozzi Virginie Tissières Yoko Fukuda-Yuzawa Brandon J Mannion Sarah Y Afzal Elizabeth A Lee Yiwen Zhu Ingrid Plajzer-Frick Catherine S Pickle Momoe Kato Tyler H Garvin Quan T Pham Anne N Harrington Jennifer A Akiyama Veena Afzal Javier Lopez-Rios Diane E Dickel Axel Visel Len A Pennacchio

Nature 2018 02 31;554(7691):239-243. Epub 2018 Jan 31.

Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.

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February 2018

Ultraconserved Enhancers Are Required for Normal Development.

Authors:
Diane E Dickel Athena R Ypsilanti Ramón Pla Yiwen Zhu Iros Barozzi Brandon J Mannion Yupar S Khin Yoko Fukuda-Yuzawa Ingrid Plajzer-Frick Catherine S Pickle Elizabeth A Lee Anne N Harrington Quan T Pham Tyler H Garvin Momoe Kato Marco Osterwalder Jennifer A Akiyama Veena Afzal John L R Rubenstein Len A Pennacchio Axel Visel

Cell 2018 01 18;172(3):491-499.e15. Epub 2018 Jan 18.

Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA; U.S. Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA; School of Natural Sciences, University of California Merced, Merced, CA 95343, USA. Electronic address:

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January 2018

Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb.

Authors:
Remo Monti Iros Barozzi Marco Osterwalder Elizabeth Lee Momoe Kato Tyler H Garvin Ingrid Plajzer-Frick Catherine S Pickle Jennifer A Akiyama Veena Afzal Niko Beerenwinkel Diane E Dickel Axel Visel Len A Pennacchio

PLoS Comput Biol 2017 Aug 21;13(8):e1005720. Epub 2017 Aug 21.

Lawrence Berkeley National Laboratory, Berkeley, California, United States of America.

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August 2017

TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.

Authors:
Sara Montagner Cristina Leoni Stefan Emming Giulia Della Chiara Chiara Balestrieri Iros Barozzi Viviana Piccolo Susan Togher Myunggon Ko Anjana Rao Gioacchino Natoli Silvia Monticelli

Cell Rep 2017 08;20(7):1744

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August 2017