Irma Joosten

Irma Joosten

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Irma Joosten

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Long-Term Effects of Experimental Human Endotoxemia on Immune Cell Function: Similarities and Differences With Sepsis.

Shock 2019 Jun;51(6):678-689

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/SHK.0000000000001222DOI Listing
June 2019

An Autocrine TNFα-Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability .

Front Immunol 2018 21;9:573. Epub 2018 Mar 21.

Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.00573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871762PMC
May 2019

DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4CD25 FOXP3 Regulatory T Cells but Does Not Affect Their Suppressive Capacity.

J Immunol Res 2018 15;2018:4973964. Epub 2018 Apr 15.

Department of Laboratory Medicine-Medical Immunology, Radboud University Medical Center (Radboudumc), Nijmegen, Netherlands.

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http://dx.doi.org/10.1155/2018/4973964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924998PMC
October 2018

TNF-α-induced protein 3 (TNFAIP3)/A20 acts as a master switch in TNF-α blockade-driven IL-17A expression.

J Allergy Clin Immunol 2018 08 14;142(2):517-529. Epub 2017 Dec 14.

Department of Laboratory Medicine, Laboratory of Medical Immunology (LMI), Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.024DOI Listing
August 2018

How uterine microbiota might be responsible for a receptive, fertile endometrium.

Hum Reprod Update 2018 07;24(4):393-415

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Geert Grooteplein 10, PO Box 9101, Internal mail 469, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/humupd/dmy012DOI Listing
July 2018

MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse.

Am J Hum Genet 2018 07 28;103(1):74-88. Epub 2018 Jun 28.

Hearing and Genes Division, Department of Otorhinolaryngology, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037131PMC
July 2018

Intradermal injection of low dose human regulatory T cells inhibits skin inflammation in a humanized mouse model.

Sci Rep 2018 07 3;8(1):10044. Epub 2018 Jul 3.

Radboud university medical center, department of Laboratory Medicine-Medical Immunology, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-28346-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030170PMC
July 2018

Evaluation of a new free light chain ELISA assay: bringing coherence with electrophoretic methods.

Clin Chem Lab Med 2018 01;56(2):312-322

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1515/cclm-2017-0339DOI Listing
January 2018

Human Cytomegalovirus Infection Increases Both Antibody- and Non-Antibody-Dependent Cellular Reactivity by Natural Killer Cells.

Transplant Direct 2017 Dec 20;3(12):e335. Epub 2017 Nov 20.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/TXD.0000000000000750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828690PMC
December 2017

Stabilizing human regulatory T cells for tolerance inducing immunotherapy.

Immunotherapy 2017 08 3;9(9):735-751. Epub 2017 Aug 3.

Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.2217/imt-2017-0017DOI Listing
August 2017

A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells.

PLoS One 2016 25;11(5):e0156311. Epub 2016 May 25.

Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156311PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880213PMC
July 2017

Human uterine lymphocytes acquire a more experienced and tolerogenic phenotype during pregnancy.

Sci Rep 2017 06 6;7(1):2884. Epub 2017 Jun 6.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, PO box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-03191-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460245PMC
June 2017

Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells.

Sci Rep 2017 02 22;7:43003. Epub 2017 Feb 22.

Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/srep43003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320448PMC
February 2017

Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study.

Immun Ageing 2017 22;14. Epub 2017 Feb 22.

Departments of Rheumatology and Clinical Immunology and Translational Immunology Groningen (TRIGR), University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9700RB Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12979-017-0087-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322590PMC
February 2017

Cell Surface Expression of HLA-Cw6 by Human Epidermal Keratinocytes: Positive Regulation by Cytokines, Lack of Correlation to a Variant Upstream of HLA-C.

J Invest Dermatol 2016 09 11;136(9):1903-1906. Epub 2016 Jun 11.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jid.2016.05.112DOI Listing
September 2016

Added effects of dexamethasone and mesenchymal stem cells on early Natural Killer cell activation.

Transpl Immunol 2016 07 30;37:1-9. Epub 2016 Apr 30.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud university medical center, Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09663274163003
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http://dx.doi.org/10.1016/j.trim.2016.04.008DOI Listing
July 2016

Inflammation-associated changes in lipid composition and the organization of the erythrocyte membrane.

BBA Clin 2016 Jun 3;5:186-92. Epub 2016 Apr 3.

Department of Biochemistry, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.bbacli.2016.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864322PMC
June 2016

Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture.

J Vis Exp 2016 Apr 8(110):e52564. Epub 2016 Apr 8.

Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Centre;

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http://dx.doi.org/10.3791/52564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941874PMC
April 2016

Prominent HLA-G Expression in Liver Disease But Not After Liver Transplantation.

Transplantation 2015 Dec;99(12):2514-22

1 Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, the Netherlands. 2 Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands. 3 Department of Pathology, Erasmus MC University Medical Centre, Rotterdam, the Netherlands. 4 Department of Viroscience, Erasmus MC University Medical Centre, Rotterdam, the Netherlands. 5 Department of Surgery, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1097/TP.0000000000000761DOI Listing
December 2015

Cytokine Release After Treatment With Rituximab in Renal Transplant Recipients.

Transplantation 2015 Sep;99(9):1907-11

1 Department of Laboratory Medicine-Medical Immunology, Radboud University Medical Center, Nijmegen, the Netherlands. 2 Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/TP.0000000000000515DOI Listing
September 2015

Quantitative measurement of immunoglobulins and free light chains using mass spectrometry.

Anal Chem 2015 Aug 28;87(16):8268-74. Epub 2015 Jul 28.

‡Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboudumc, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.5b01263DOI Listing
August 2015

KIR and Human Leukocyte Antigen Genotype Associated Risk of Cytomegalovirus Disease in Renal Transplant Patients.

Transplantation 2015 Jul;99(7):1506-13

1 Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, the Netherlands. 2 Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands. 3 Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/TP.0000000000000497DOI Listing
July 2015

Balance of Treg versus T-effector cells during systemic treatment with adalimumab and topical treatment with calcipotriol-betamethasone dipropionate ointment.

Exp Dermatol 2015 Jan 18;24(1):65-7. Epub 2014 Nov 18.

Department of Dermatology, Radboud university medical center, Nijmegen, The Netherlands; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/exd.12575DOI Listing
January 2015

Soluble CD30 does not predict late acute rejection or safe tapering of immunosuppression in renal transplantation.

Transpl Immunol 2015 Jan 6;32(1):18-22. Epub 2014 Nov 6.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre, PO Box 9101 6500HB Nijmegen, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09663274140010
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http://dx.doi.org/10.1016/j.trim.2014.10.006DOI Listing
January 2015

The number of CCR5 expressing CD4+ T lymphocytes is lower in HIV-infected long-term non-progressors with viral control compared to normal progressors: a cross-sectional study.

BMC Infect Dis 2014 Dec 13;14:683. Epub 2014 Dec 13.

Department of Internal Medicine, Radboud University Medical Center, Route 456, PO Box 910, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12879-014-0683-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271479PMC
December 2014

Cellular sources of IL-17 in psoriasis: a paradigm shift?

Exp Dermatol 2014 Nov;23(11):799-803

Department of Dermatology, Radboud university medical center, Nijmegen, The Netherlands; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/exd.12487DOI Listing
November 2014

Immune responses to stress in rheumatoid arthritis and psoriasis.

Rheumatology (Oxford) 2014 Oct 20;53(10):1844-8. Epub 2014 May 20.

Department of Medical Psychology, Radboud University Medical Center, Nijmegen, Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Department of Rheumatology and Clinical Immunology & Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Department of Dermatology, Radboud University Medical Center, Department for Health Evidence, Radboud University Medical Center, Department of Rheumatology, Sint Maartenskliniek and Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands. Department of Medical Psychology, Radboud University Medical Center, Nijmegen, Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Department of Rheumatology and Clinical Immunology & Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Department of Dermatology, Radboud University Medical Center, Department for Health Evidence, Radboud University Medical Center, Department of Rheumatology, Sint Maartenskliniek and Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/keu221DOI Listing
October 2014

Redefining Strategies to Introduce Tolerance-Inducing Cellular Therapy in Human beings to Combat Autoimmunity and Transplantation Reactions.

Front Immunol 2014 15;5:392. Epub 2014 Aug 15.

Laboratory for Translational Immunology, Center for Molecular and Cellular Immunology, Wilhelmina Children's Hospital, University Medical Centre Utrecht , Utrecht , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2014.00392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133652PMC
September 2014

In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORγt and IL-17.

J Invest Dermatol 2014 May 6;134(5):1276-1284. Epub 2013 Dec 6.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands; Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/jid.2013.526DOI Listing
May 2014

Phosphatidylserine exposure on stored red blood cells as a parameter for donor-dependent variation in product quality.

Blood Transfus 2014 Apr 3;12(2):204-9. Epub 2013 Oct 3.

Department of Biochemistry, Radboud University Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://www.bloodtransfusion.it/articolo.aspx?idart=002691&am
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http://dx.doi.org/10.2450/2013.0106-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039702PMC
April 2014

Targeting PKC in human T cells using sotrastaurin (AEB071) preserves regulatory T cells and prevents IL-17 production.

J Invest Dermatol 2014 Apr 5;134(4):975-983. Epub 2013 Nov 5.

Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.459DOI Listing
April 2014

Crosstalk between keratinocytes and T cells in a 3D microenvironment: a model to study inflammatory skin diseases.

J Invest Dermatol 2014 Mar 11;134(3):719-727. Epub 2013 Oct 11.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.417DOI Listing
March 2014

Selective expansion of human natural killer cells leads to enhanced alloreactivity.

Cell Mol Immunol 2014 Mar 18;11(2):160-8. Epub 2013 Nov 18.

Department of Laboratory Medicine-Laboratory of Medical Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/cmi.2013.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003378PMC
March 2014

Gateway to understanding microparticles: standardized isolation and identification of plasma membrane-derived vesicles.

Nanomedicine (Lond) 2013 Oct;8(10):1657-68

Department of Biochemistry, Radboud University Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.2217/nnm.13.149DOI Listing
October 2013

Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells.

Blood 2013 Sep 15;122(13):2213-23. Epub 2013 Aug 15.

Department of Laboratory Medicine-Medical Immunology, Radboud University Medical Centre, Nijmegen, The Netherlands;

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-03-48
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http://dx.doi.org/10.1182/blood-2013-03-489443DOI Listing
September 2013

The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production.

Transpl Immunol 2013 Jun 4;28(4):183-8. Epub 2013 May 4.

Department of Medicine (463), Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.trim.2013.04.008DOI Listing
June 2013

High-dose vitamin D3 supplementation is a requisite for modulation of skin-homing markers on regulatory T cells in HIV-infected patients.

AIDS Res Hum Retroviruses 2013 Feb 29;29(2):299-306. Epub 2012 Aug 29.

Department of Laboratory Medicine, Laboratory Medical Immunology, Radboud University Nijmegen Medical Center, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1089/AID.2012.0051DOI Listing
February 2013

Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis.

J Clin Invest 2013 Feb 25;123(2):917-27. Epub 2013 Jan 25.

Department of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, P.O. Box 9101, Nijmegen 6500 HB, The Netherlands.

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http://dx.doi.org/10.1172/JCI65642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561798PMC
February 2013

Storage-induced changes in erythrocyte membrane proteins promote recognition by autoantibodies.

PLoS One 2012 3;7(8):e42250. Epub 2012 Aug 3.

Department of Laboratory Medicine - Laboratory of Medical Immunology, Radboud University Medical Centre, Nijmegen Institute for Infection Inflammation and Immunity, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042250PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411782PMC
January 2013

Co-culture of healthy human keratinocytes and T-cells promotes keratinocyte chemokine production and RORγt-positive IL-17 producing T-cell populations.

J Dermatol Sci 2013 Jan 17;69(1):44-53. Epub 2012 Oct 17.

Department of Laboratory Medicine - Medical Immunology, Radboud University Medical Centre, Nijmegen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S09231811120030
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http://dx.doi.org/10.1016/j.jdermsci.2012.10.004DOI Listing
January 2013

Defining early human NK cell developmental stages in primary and secondary lymphoid tissues.

PLoS One 2012 3;7(2):e30930. Epub 2012 Feb 3.

Department of Laboratory Medicine-Laboratory of Medical Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030930PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272048PMC
September 2012

Rho kinase inhibitor Y-27632 prolongs the life span of adult human keratinocytes, enhances skin equivalent development, and facilitates lentiviral transduction.

Tissue Eng Part A 2012 Sep 5;18(17-18):1827-36. Epub 2012 Jun 5.

Department of Dermatology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1089/ten.TEA.2011.0616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432898PMC
September 2012

Seasonal variation in vitamin D₃ levels is paralleled by changes in the peripheral blood human T cell compartment.

PLoS One 2012 3;7(1):e29250. Epub 2012 Jan 3.

Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029250PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250425PMC
May 2012

Translating the role of vitamin D3 in infectious diseases.

Crit Rev Microbiol 2012 May 5;38(2):122-35. Epub 2012 Feb 5.

Radboud University Nijmegen Medical Center, Department of Laboratory Medicine, Laboratory Medical Immunology, Nijmegen, Netherlands.

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http://dx.doi.org/10.3109/1040841X.2011.622716DOI Listing
May 2012

Analyzing the homeostasis of signaling proteins by a combination of Western blot and fluorescence correlation spectroscopy.

Biophys J 2011 Dec;101(11):2807-15

Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.bpj.2011.09.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297796PMC
December 2011

Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin.

J Invest Dermatol 2011 Sep 9;131(9):1853-60. Epub 2011 Jun 9.

Department of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/jid.2011.139DOI Listing
September 2011

Donor and recipient HLA/KIR genotypes do not predict liver transplantation outcome.

Transpl Int 2011 Sep 14;24(9):932-42. Epub 2011 Jun 14.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1432-2277.2011.01286.xDOI Listing
September 2011

1,25-dihydroxyvitamin D3 modulates cytokine production induced by Candida albicans: impact of seasonal variation of immune responses.

J Infect Dis 2011 Jan;203(1):122-30

Department of Laboratory Medicine, Radboud University Nijmegen Medical Center; 3Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/infdis/jiq008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086448PMC
January 2011

Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation.

Liver Transpl 2010 Jul;16(7):895-908

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/lt.22080DOI Listing
July 2010

DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells.

Sci Signal 2010 Feb 23;3(110):ra14. Epub 2010 Feb 23.

Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.

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http://stke.sciencemag.org/cgi/doi/10.1126/scisignal.2000467
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http://dx.doi.org/10.1126/scisignal.2000467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793721PMC
February 2010

Immunotherapy with regulatory T cells in transplantation.

Immunotherapy 2009 Sep;1(5):855-71

Department of Blood Transfusion & Transplantation Immunology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.2217/imt.09.45DOI Listing
September 2009

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells.

Blood 2008 Sep 10;112(6):2340-52. Epub 2008 Jul 10.

Department of Blood Transfusion and Transplantation Immunology, Radboud University Nijmegen Medical Centre, The Netherlands.

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http://www.bloodjournal.org/content/112/6/2340.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2008-01-13
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http://dx.doi.org/10.1182/blood-2008-01-133967DOI Listing
September 2008

Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation.

PLoS One 2008 Sep 8;3(9):e3161. Epub 2008 Sep 8.

Department of Bloodtransfusion and Transplantation Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003161PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2522271PMC
September 2008

A novel (Leu183Pro-)mutation in the HFE-gene co-inherited with the Cys282Tyr mutation in two unrelated Dutch hemochromatosis patients.

Blood Cells Mol Dis 2008 May-Jun;40(3):334-8. Epub 2007 Nov 26.

Department of Clinical Chemistry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S10799796070022
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http://dx.doi.org/10.1016/j.bcmd.2007.10.003DOI Listing
August 2008

KIR2DS5 is associated with leukemia free survival after HLA identical stem cell transplantation in chronic myeloid leukemia patients.

Mol Immunol 2008 Aug 16;45(13):3631-8. Epub 2008 Jun 16.

Department of Blood Transfusion and Transplantation Immunology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2008.04.016DOI Listing
August 2008

Immunological monitoring of renal transplant recipients to predict acute allograft rejection following the discontinuation of tacrolimus.

PLoS One 2008 Jul 16;3(7):e2711. Epub 2008 Jul 16.

Department of Blood Transfusion and Transplantation Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002711PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442873PMC
July 2008

Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy.

PLoS One 2008 May 21;3(5):e2233. Epub 2008 May 21.

Department of Bloodtransfusion and Transplantation Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002233PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376059PMC
May 2008

The presence of donor-specific human leukocyte antigen antibodies does not preclude successful withdrawal of tacrolimus in stable renal transplant recipients.

Transplantation 2007 Nov;84(9):1092-6

Department of Blood Transfusion and Transplantation Immunology, Radboud University Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/01.tp.0000285994.29305.b1DOI Listing
November 2007

KIR gene and KIR ligand analysis to predict graft rejection after renal transplantation.

Transplantation 2007 Oct;84(8):1045-51

Department of Blood Transfusion and Transplantation Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/01.tp.0000286097.11173.70DOI Listing
October 2007

Allogeneic stimulation of naturally occurring CD4+CD25+ T cells induces strong regulatory capacity with increased donor-reactivity.

Transpl Immunol 2007 Jun 31;17(4):237-42. Epub 2007 Jan 31.

Department of Bloodtransfusion and Transplantation Immunology, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.trim.2007.01.004DOI Listing
June 2007

The immunosuppressive drug FK778 induces regulatory activity in stimulated human CD4+ CD25- T cells.

Blood 2007 Jan 10;109(1):244-52. Epub 2006 Aug 10.

Radboud University Nijmegen Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1182/blood-2006-05-021931DOI Listing
January 2007

Antigen-specific regulatory T-cell subsets in transplantation tolerance regulatory T-cell subset quality reduces the need for quantity.

Hum Immunol 2006 Sep 27;67(9):665-75. Epub 2006 Jun 27.

Department of Blood Transfusion and Transplantation Immunology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.humimm.2006.05.007DOI Listing
September 2006