Publications by authors named "Iris Postmus"

31Publications

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Authors:
Alexander Teumer Layal Chaker Stefan Groeneweg Yong Li Celia Di Munno Caterina Barbieri Ulla T Schultheiss Michela Traglia Tarunveer S Ahluwalia Masato Akiyama Emil Vincent R Appel Dan E Arking Alice Arnold Arne Astrup Marian Beekman John P Beilby Sofie Bekaert Eric Boerwinkle Suzanne J Brown Marc De Buyzere Purdey J Campbell Graziano Ceresini Charlotte Cerqueira Francesco Cucca Ian J Deary Joris Deelen Kai-Uwe Eckardt Arif B Ekici Johan G Eriksson Luigi Ferrrucci Tom Fiers Edoardo Fiorillo Ian Ford Caroline S Fox Christian Fuchsberger Tessel E Galesloot Christian Gieger Martin Gögele Alessandro De Grandi Niels Grarup Karin Halina Greiser Kadri Haljas Torben Hansen Sarah E Harris Diana van Heemst Martin den Heijer Andrew A Hicks Wouter den Hollander Georg Homuth Jennie Hui M Arfan Ikram Till Ittermann Richard A Jensen Jiaojiao Jing J Wouter Jukema Eero Kajantie Yoichiro Kamatani Elisa Kasbohm Jean-Marc Kaufman Lambertus A Kiemeney Margreet Kloppenburg Florian Kronenberg Michiaki Kubo Jari Lahti Bruno Lapauw Shuo Li David C M Liewald Ee Mun Lim Allan Linneberg Michela Marina Deborah Mascalzoni Koichi Matsuda Daniel Medenwald Christa Meisinger Ingrid Meulenbelt Tim De Meyer Henriette E Meyer Zu Schwabedissen Rafael Mikolajczyk Matthijs Moed Romana T Netea-Maier Ilja M Nolte Yukinori Okada Mauro Pala Cristian Pattaro Oluf Pedersen Astrid Petersmann Eleonora Porcu Iris Postmus Peter P Pramstaller Bruce M Psaty Yolande F M Ramos Rajesh Rawal Paul Redmond J Brent Richards Ernst R Rietzschel Fernando Rivadeneira Greet Roef Jerome I Rotter Cinzia F Sala David Schlessinger Elizabeth Selvin P Eline Slagboom Nicole Soranzo Thorkild I A Sørensen Timothy D Spector John M Starr David J Stott Youri Taes Daniel Taliun Toshiko Tanaka Betina Thuesen Daniel Tiller Daniela Toniolo Andre G Uitterlinden W Edward Visser John P Walsh Scott G Wilson Bruce H R Wolffenbuttel Qiong Yang Hou-Feng Zheng Anne Cappola Robin P Peeters Silvia Naitza Henry Völzke Serena Sanna Anna Köttgen Theo J Visser Marco Medici

Nat Commun 2018 10 26;9(1):4455. Epub 2018 Oct 26.

Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-06356-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203810PMC
October 2018

Visit-to-visit lipid variability: Clinical significance, effects of lipid-lowering treatment, and (pharmaco) genetics.

J Clin Lipidol 2018 Mar - Apr;12(2):266-276.e3. Epub 2018 Jan 11.

Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Section of Gerontology and Geriatrics, Department of Internal Medicine, LUMC, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacl.2018.01.001DOI Listing
September 2019

Lessons from Mendelian randomization studies on liver biomarkers: response to Abbasi.

Int J Epidemiol 2017 10;46(5):1713-1714

Department of Internal Medicine, Section of Gerontology and Geriatrics.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ije/dyx064DOI Listing
October 2017

Effect of intranasally administered insulin on cerebral blood flow and perfusion; a randomized experiment in young and older adults.

Aging (Albany NY) 2017 03;9(3):790-802

Department of Internal Medicine, section Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.101192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391232PMC
March 2017

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.

J Med Genet 2016 12 1;53(12):835-845. Epub 2016 Sep 1.

Department of Atherosclerosis Research, Children's Hospital Oakland Research Institute, Oakland, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jmedgenet-2016-103966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309131PMC
December 2016

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

Authors:
Norihiro Kato Marie Loh Fumihiko Takeuchi Niek Verweij Xu Wang Weihua Zhang Tanika N Kelly Danish Saleheen Benjamin Lehne Irene Mateo Leach Alexander W Drong James Abbott Simone Wahl Sian-Tsung Tan William R Scott Gianluca Campanella Marc Chadeau-Hyam Uzma Afzal Tarunveer S Ahluwalia Marc Jan Bonder Peng Chen Abbas Dehghan Todd L Edwards Tõnu Esko Min Jin Go Sarah E Harris Jaana Hartiala Silva Kasela Anuradhani Kasturiratne Chiea-Chuen Khor Marcus E Kleber Huaixing Li Zuan Yu Mok Masahiro Nakatochi Nur Sabrina Sapari Richa Saxena Alexandre F R Stewart Lisette Stolk Yasuharu Tabara Ai Ling Teh Ying Wu Jer-Yuarn Wu Yi Zhang Imke Aits Alexessander Da Silva Couto Alves Shikta Das Rajkumar Dorajoo Jemma C Hopewell Yun Kyoung Kim Robert W Koivula Jian'an Luan Leo-Pekka Lyytikäinen Quang N Nguyen Mark A Pereira Iris Postmus Olli T Raitakari Molly Scannell Bryan Robert A Scott Rossella Sorice Vinicius Tragante Michela Traglia Jon White Ken Yamamoto Yonghong Zhang Linda S Adair Alauddin Ahmed Koichi Akiyama Rasheed Asif Tin Aung Inês Barroso Andrew Bjonnes Timothy R Braun Hui Cai Li-Ching Chang Chien-Hsiun Chen Ching-Yu Cheng Yap-Seng Chong Rory Collins Regina Courtney Gail Davies Graciela Delgado Loi D Do Pieter A Doevendans Ron T Gansevoort Yu-Tang Gao Tanja B Grammer Niels Grarup Jagvir Grewal Dongfeng Gu Gurpreet S Wander Anna-Liisa Hartikainen Stanley L Hazen Jing He Chew-Kiat Heng James E Hixson Albert Hofman Chris Hsu Wei Huang Lise L N Husemoen Joo-Yeon Hwang Sahoko Ichihara Michiya Igase Masato Isono Johanne M Justesen Tomohiro Katsuya Muhammad G Kibriya Young Jin Kim Miyako Kishimoto Woon-Puay Koh Katsuhiko Kohara Meena Kumari Kenneth Kwek Nanette R Lee Jeannette Lee Jiemin Liao Wolfgang Lieb David C M Liewald Tatsuaki Matsubara Yumi Matsushita Thomas Meitinger Evelin Mihailov Lili Milani Rebecca Mills Nina Mononen Martina Müller-Nurasyid Toru Nabika Eitaro Nakashima Hong Kiat Ng Kjell Nikus Teresa Nutile Takayoshi Ohkubo Keizo Ohnaka Sarah Parish Lavinia Paternoster Hao Peng Annette Peters Son T Pham Mohitha J Pinidiyapathirage Mahfuzar Rahman Hiromi Rakugi Olov Rolandsson Michelle Ann Rozario Daniela Ruggiero Cinzia F Sala Ralhan Sarju Kazuro Shimokawa Harold Snieder Thomas Sparsø Wilko Spiering John M Starr David J Stott Daniel O Stram Takao Sugiyama Silke Szymczak W H Wilson Tang Lin Tong Stella Trompet Väinö Turjanmaa Hirotsugu Ueshima André G Uitterlinden Satoshi Umemura Marja Vaarasmaki Rob M van Dam Wiek H van Gilst Dirk J van Veldhuisen Jorma S Viikari Melanie Waldenberger Yiqin Wang Aili Wang Rory Wilson Tien-Yin Wong Yong-Bing Xiang Shuhei Yamaguchi Xingwang Ye Robin D Young Terri L Young Jian-Min Yuan Xueya Zhou Folkert W Asselbergs Marina Ciullo Robert Clarke Panos Deloukas Andre Franke Paul W Franks Steve Franks Yechiel Friedlander Myron D Gross Zhirong Guo Torben Hansen Marjo-Riitta Jarvelin Torben Jørgensen J Wouter Jukema Mika Kähönen Hiroshi Kajio Mika Kivimaki Jong-Young Lee Terho Lehtimäki Allan Linneberg Tetsuro Miki Oluf Pedersen Nilesh J Samani Thorkild I A Sørensen Ryoichi Takayanagi Daniela Toniolo Habibul Ahsan Hooman Allayee Yuan-Tsong Chen John Danesh Ian J Deary Oscar H Franco Lude Franke Bastiaan T Heijman Joanna D Holbrook Aaron Isaacs Bong-Jo Kim Xu Lin Jianjun Liu Winfried März Andres Metspalu Karen L Mohlke Dharambir K Sanghera Xiao-Ou Shu Joyce B J van Meurs Eranga Vithana Ananda R Wickremasinghe Cisca Wijmenga Bruce H W Wolffenbuttel Mitsuhiro Yokota Wei Zheng Dingliang Zhu Paolo Vineis Soterios A Kyrtopoulos Jos C S Kleinjans Mark I McCarthy Richie Soong Christian Gieger James Scott Yik-Ying Teo Jiang He Paul Elliott E Shyong Tai Pim van der Harst Jaspal S Kooner John C Chambers

Nat Genet 2015 11 21;47(11):1282-1293. Epub 2015 Sep 21.

Department of Epidemiology and Biostatistics, Imperial College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719169PMC
November 2015

Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship.

J Clin Endocrinol Metab 2015 Oct 31;100(10):3806-13. Epub 2015 Jul 31.

Departments of Gerontology and Geriatrics (S.W.J., E.v.d.S., A.A.A., I.P., R.G.W., D.v.H.), Endocrinology and Metabolic Diseases (F.R., H.P.), Clinical Chemistry and Laboratory Medicine (B.E.B., C.M.C.), Radiology (J.v.d.G.), and Section of Molecular Epidemiology, Department of Medical Statistics (P.E.S.), Leiden University Medical Center, and Leiden Institute for Brain and Cognition (J.v.d.G.), Leiden University, Albinusdreef 2, 2300 RC Leiden, The Netherlands; and Department of Public Health (R.G.W.), University of Copenhagen, Gothersgade 160, 1123, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2015-2624DOI Listing
October 2015

LDL cholesterol still a problem in old age? A Mendelian randomization study.

Int J Epidemiol 2015 Apr 7;44(2):604-12. Epub 2015 Apr 7.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands, Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands, Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands, Leyden Academy of Vitality and Ageing, Leiden, The Netherlands, Faculty of Health and Medical Sciences, Department of Public Health, University of Copenhagen, Copenhagen, Denmark, Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands and Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands, Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands, Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands, Leyden Academy of Vitality and Ageing, Leiden, The Netherlands, Faculty of Health and Medical Sciences, Department of Public Health, University of Copenhagen, Copenhagen, Denmark, Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands and Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands, Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands, Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands, Leyd

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ije/dyv031DOI Listing
April 2015

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels.

Nat Commun 2015 Mar 9;6:6065. Epub 2015 Mar 9.

Department of Epidemiology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms7065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366498PMC
March 2015

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers.

PLoS Genet 2014 Dec 4;10(12):e1004799. Epub 2014 Dec 4.

BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1004799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256159PMC
December 2014

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.

Authors:
Iris Postmus Stella Trompet Harshal A Deshmukh Michael R Barnes Xiaohui Li Helen R Warren Daniel I Chasman Kaixin Zhou Benoit J Arsenault Louise A Donnelly Kerri L Wiggins Christy L Avery Paula Griffin QiPing Feng Kent D Taylor Guo Li Daniel S Evans Albert V Smith Catherine E de Keyser Andrew D Johnson Anton J M de Craen David J Stott Brendan M Buckley Ian Ford Rudi G J Westendorp P Eline Slagboom Naveed Sattar Patricia B Munroe Peter Sever Neil Poulter Alice Stanton Denis C Shields Eoin O'Brien Sue Shaw-Hawkins Y-D Ida Chen Deborah A Nickerson Joshua D Smith Marie Pierre Dubé S Matthijs Boekholdt G Kees Hovingh John J P Kastelein Paul M McKeigue John Betteridge Andrew Neil Paul N Durrington Alex Doney Fiona Carr Andrew Morris Mark I McCarthy Leif Groop Emma Ahlqvist Joshua C Bis Kenneth Rice Nicholas L Smith Thomas Lumley Eric A Whitsel Til Stürmer Eric Boerwinkle Julius S Ngwa Christopher J O'Donnell Ramachandran S Vasan Wei-Qi Wei Russell A Wilke Ching-Ti Liu Fangui Sun Xiuqing Guo Susan R Heckbert Wendy Post Nona Sotoodehnia Alice M Arnold Jeanette M Stafford Jingzhong Ding David M Herrington Stephen B Kritchevsky Gudny Eiriksdottir Leonore J Launer Tamara B Harris Audrey Y Chu Franco Giulianini Jean G MacFadyen Bryan J Barratt Fredrik Nyberg Bruno H Stricker André G Uitterlinden Albert Hofman Fernando Rivadeneira Valur Emilsson Oscar H Franco Paul M Ridker Vilmundur Gudnason Yongmei Liu Joshua C Denny Christie M Ballantyne Jerome I Rotter L Adrienne Cupples Bruce M Psaty Colin N A Palmer Jean-Claude Tardif Helen M Colhoun Graham Hitman Ronald M Krauss J Wouter Jukema Mark J Caulfield

Nat Commun 2014 Oct 28;5:5068. Epub 2014 Oct 28.

1] NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK [2] Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London EC1M6BQ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms6068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220464PMC
October 2014

In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study.

Atherosclerosis 2014 Jul 26;235(1):58-64. Epub 2014 Apr 26.

Department of Cardiology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00219150140020
Publisher Site
http://dx.doi.org/10.1016/j.atherosclerosis.2014.04.009DOI Listing
July 2014

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Hum Mol Genet 2014 Aug 31;23(16):4420-32. Epub 2014 Mar 31.

Department of Molecular Epidemiology, Netherlands Consortium for Healthy Ageing,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddu139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103672PMC
August 2014

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers.

Int J Epidemiol 2014 Jun 14;43(3):878-86. Epub 2014 Jan 14.

Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands, Netherlands Consortium for Healthy Ageing, Leiden University Medical Center, Leiden, The Netherlands, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK, Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands, Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Estonian Genome Center, University of Tartu, Tartu, Estonia, Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands and Department of Medical Statistics, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands, Netherlands Consortium for Healthy Ageing, Leiden University Medical Center, Leiden, The Netherlands, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK, Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands, Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Estonian Genome Center, University of Tartu, Tartu, Estonia, Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands and Department of Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
https://academic.oup.com/ije/article-lookup/doi/10.1093/ije/
Publisher Site
http://dx.doi.org/10.1093/ije/dyt267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052133PMC
June 2014

Re: "Mendelian randomization and estimation of treatment efficacy for chronic diseases".

Am J Epidemiol 2014 Jan 13;179(2):264. Epub 2013 Dec 13.

Department of Clinical Epidemiology, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/aje/kwt306DOI Listing
January 2014

Statins work around the world.

Curr Med Res Opin 2013 Jul 10;29(7):747-9. Epub 2013 May 10.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1185/03007995.2013.799392DOI Listing
July 2013

Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives.

Pharmacogenomics 2012 May;13(7):831-40

Department of Gerontology & Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs.12.25DOI Listing
May 2012