Irina Mikhailenko

Irina Mikhailenko

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Irina Mikhailenko

Irina Mikhailenko

Publications by authors named "Irina Mikhailenko"

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26Publications

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LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages.

PLoS One 2015 10;10(6):e0128903. Epub 2015 Jun 10.

Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD 21201, United States of America; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, United States of America; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128903PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463855PMC
March 2016

LRP1 protects the vasculature by regulating levels of connective tissue growth factor and HtrA1.

Arterioscler Thromb Vasc Biol 2013 Sep 18;33(9):2137-46. Epub 2013 Jul 18.

Center for Vascular and Inflammatory Disease, Departments of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1161/ATVBAHA.113.301893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892666PMC
September 2013

Tissue transglutaminase promotes PDGF/PDGFR-mediated signaling and responses in vascular smooth muscle cells.

J Cell Physiol 2012 May;227(5):2089-96

Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1002/jcp.22938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210882PMC
May 2012

Identification of VLDLR as a novel endothelial cell receptor for fibrin that modulates fibrin-dependent transendothelial migration of leukocytes.

Blood 2012 Jan 17;119(2):637-44. Epub 2011 Nov 17.

Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, 21201, USA.

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http://dx.doi.org/10.1182/blood-2011-09-382580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257021PMC
January 2012

Murine missing in metastasis (MIM) mediates cell polarity and regulates the motility response to growth factors.

PLoS One 2011 9;6(6):e20845. Epub 2011 Jun 9.

The Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, Maryland, United of States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020845PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111439PMC
October 2011

LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.

J Neurosci 2011 Jul;31(30):10836-46

Center for Vascular and Inflammatory Diseases and the Departments of Surgery and Physiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5065-10.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189500PMC
July 2011

Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomes.

PLoS One 2011 Apr 27;6(4):e19414. Epub 2011 Apr 27.

Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019414PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083433PMC
April 2011

Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease.

Int Arch Allergy Immunol 2010 24;152(1):75-80. Epub 2009 Nov 24.

Sezione Biotecnologia e Biologia Molecolare, Dipartimento di Medicina Sperimentale, Seconda Università degli Studi di Napoli, Naples, Italy.

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http://dx.doi.org/10.1159/000260087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956008PMC
May 2010

Microglial low-density lipoprotein receptor-related protein 1 modulates c-Jun N-terminal kinase activation.

J Neuroimmunol 2009 Sep 7;214(1-2):25-32. Epub 2009 Jul 7.

Department of Neuroscience, Georgetown University, Washington, DC 20057-1464, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016557280900227
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http://dx.doi.org/10.1016/j.jneuroim.2009.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745483PMC
September 2009

Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase.

J Biol Chem 2009 Jun 22;284(24):16693-703. Epub 2009 Apr 22.

Department of Biochemistry and Molecular Biology, Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1074/jbc.M109.010769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713562PMC
June 2009

IL-4 promotes the formation of multinucleated giant cells from macrophage precursors by a STAT6-dependent, homotypic mechanism: contribution of E-cadherin.

J Leukoc Biol 2007 Dec 12;82(6):1542-53. Epub 2007 Sep 12.

Department of Orthopedics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1189/jlb.0107058DOI Listing
December 2007

Localization of the low-density lipoprotein receptor-related protein regions involved in binding to the A2 domain of coagulation factor VIII.

Thromb Haemost 2007 Dec;98(6):1170-81

Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

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December 2007

Cell-surface transglutaminase undergoes internalization and lysosomal degradation: an essential role for LRP1.

J Cell Sci 2007 Sep 21;120(Pt 18):3188-99. Epub 2007 Aug 21.

Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1242/jcs.010397DOI Listing
September 2007

Fluorescence lifetime imaging microscopy (FLIM) detects stimulus-dependent phosphorylation of the low density lipoprotein receptor-related protein (LRP) in primary neurons.

Biochem Biophys Res Commun 2006 Oct 14;349(1):24-30. Epub 2006 Aug 14.

Alzheimer's Disease Research Unit, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.bbrc.2006.07.212DOI Listing
October 2006

RAP uses a histidine switch to regulate its interaction with LRP in the ER and Golgi.

Mol Cell 2006 May;22(3):423-30

Protein-Nucleic Acid Interaction Section, Structural Biophysics Laboratory, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1016/j.molcel.2006.04.011DOI Listing
May 2006

Platelet-derived growth factor receptor-beta (PDGFR-beta) activation promotes its association with the low density lipoprotein receptor-related protein (LRP). Evidence for co-receptor function.

J Biol Chem 2005 Jul 8;280(30):27872-8. Epub 2005 Jun 8.

Department of Surgery and Physiology, University of Maryland School of Medicine, 15601 Crabbs Branch Way, Rockville, Maryland 20855, USA.

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http://dx.doi.org/10.1074/jbc.M505410200DOI Listing
July 2005

Modulation of the LDL receptor and LRP levels by HIV protease inhibitors.

J Lipid Res 2003 Oct 1;44(10):1859-69. Epub 2003 Jul 1.

Department of Vascular Biology, Jerome H. Holland Laboratories, American Red Cross, Rockville, MD 20855, USA.

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http://dx.doi.org/10.1194/jlr.M200487-JLR200DOI Listing
October 2003

The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.

J Biol Chem 2002 May 26;277(18):16160-6. Epub 2002 Feb 26.

Department of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1074/jbc.M201401200DOI Listing
May 2002