Irina Elovaara

Irina Elovaara

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Irina Elovaara

Publications by authors named "Irina Elovaara"

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Gene expression profiles of TNF-like cytokine 1A (TL1A) and its receptors death receptor 3 (DR3) and decoy receptor 3 (DcR3) in multiple sclerosis.

J Neuroimmunol 2019 Oct 14;335:577020. Epub 2019 Aug 14.

Neuroimmunology Unit, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland; Neuro Group, BioMediTech, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1016/j.jneuroim.2019.577020DOI Listing
October 2019

Effects of inflammatory cytokines IFN-γ, TNF-α and IL-6 on the viability and functionality of human pluripotent stem cell-derived neural cells.

J Neuroimmunol 2019 Jun 29;331:36-45. Epub 2018 Aug 29.

Neuro Group, BioMeditech, The Faculty of Medicine and Life Sciences, University of Tampere, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2018.07.010DOI Listing
June 2019

Diffusion tensor imaging and disability progression in multiple sclerosis: A 4-year follow-up study.

Brain Behav 2019 01 26;9(1):e01194. Epub 2018 Dec 26.

Faculty of Medicine and Life Sciences, Tampere University, Tampere, Finland.

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http://dx.doi.org/10.1002/brb3.1194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346728PMC
January 2019

JCPyV microRNA in plasma inversely correlates with JCPyV seropositivity among long-term natalizumab-treated relapsing-remitting multiple sclerosis patients.

J Neurovirol 2017 10 22;23(5):734-741. Epub 2017 Aug 22.

Department of Virology, Medicum, University of Helsinki and Helsinki University Hospital Laboratory, Helsinki, Finland.

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http://dx.doi.org/10.1007/s13365-017-0560-xDOI Listing
October 2017

Circulating microRNAs as biomarkers in progressive multiple sclerosis.

Mult Scler 2017 Mar 11;23(3):403-412. Epub 2016 Jul 11.

Neuroimmunology Unit, School of Medicine, University of Tampere, Tampere, Finland/Department of Neurology, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1177/1352458516651141DOI Listing
March 2017

Adipsin Is Associated with Multiple Sclerosis: A Follow-Up Study of Adipokines.

Mult Scler Int 2015 8;2015:371734. Epub 2015 Nov 8.

Neuroimmunology Unit, Medical School, University of Tampere, Tampere University Hospital, Biokatu 10, 33520 Tampere, Finland ; Department of Neurology, Tampere University Hospital, Teiskontie 35, 33520 Tampere, Finland.

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http://dx.doi.org/10.1155/2015/371734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655075PMC
December 2015

Longitudinal assessment of clinically isolated syndrome with diffusion tensor imaging and volumetric MRI.

Clin Imaging 2015 Mar-Apr;39(2):207-12. Epub 2014 Oct 23.

Neuroimmunology Unit, Medical School, University of Tampere, Tampere, Finland; Department of Neurology, Tampere University Hospital, Tampere, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.clinimag.2014.10.014DOI Listing
October 2015

Hemispheric asymmetry measured by texture analysis and diffusion tensor imaging in two multiple sclerosis subtypes.

Acta Radiol 2015 Jul 14;56(7):844-51. Epub 2014 Jul 14.

Department of Electronics and Communications Engineering, Tampere University of Technology, Tampere, Finland Department of Radiology, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1177/0284185114539323DOI Listing
July 2015

Association between soluble L-selectin and anti-JCV antibodies in natalizumab-treated relapsing-remitting MS patients.

Mult Scler Relat Disord 2015 Jul 17;4(4):334-8. Epub 2015 Jun 17.

Neuroimmunology Unit, Medical School, University of Tampere, Tampere, Finland; Department of Neurology, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1016/j.msard.2015.06.008DOI Listing
July 2015

Analysis of apoptosis-related genes in patients with clinically isolated syndrome and their association with conversion to multiple sclerosis.

J Neuroimmunol 2015 Mar 25;280:43-8. Epub 2015 Feb 25.

Neuroimmunology Unit, Medical School, University of Tampere and Tampere University Hospital, Tampere, Finland; Department of Neurology, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1016/j.jneuroim.2015.02.006DOI Listing
March 2015

MR image texture in Parkinson's disease: a longitudinal study.

Acta Radiol 2015 Jan 10;56(1):97-104. Epub 2014 Jan 10.

Department of Radiology, Medical Imaging Center and Hospital Pharmacy, Tampere University Hospital, Tampere, Finland Tampere Medical School, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1177/0284185113519775DOI Listing
January 2015

Increasing Incidence in Relapsing-Remitting MS and High Rates among Young Women in Finland: A Thirty-Year Follow-Up.

Mult Scler Int 2014 9;2014:186950. Epub 2014 Nov 9.

School of Medicine, University of Tampere, Arvo 312, 33014 Tampere, Finland ; Tampere University Hospital, P.O. Box 2000, 33521 Tampere, Finland.

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http://dx.doi.org/10.1155/2014/186950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241579PMC
November 2014

Impact of atrial fibrillation and inadequate antithrombotic management on mortality in acute neurovascular syndrome.

J Stroke Cerebrovasc Dis 2014 Oct 23;23(9):2256-64. Epub 2014 Aug 23.

School of Medicine, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2014.04.017DOI Listing
October 2014

Clinical MRI for iron detection in Parkinson's disease.

Clin Imaging 2013 Jul-Aug;37(4):631-6. Epub 2013 Mar 20.

Medical Imaging Centre, Department of Radiology, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1016/j.clinimag.2013.02.001DOI Listing
June 2014

Imaging brain iron and diffusion patterns: a follow-up study of Parkinson's disease in the initial stages.

Acad Radiol 2014 Jan;21(1):64-71

Department of Radiology, Medical Imaging Centre, Tampere University Hospital, Teiskontie 35, Post Box 2000, 33520 Tampere, Finland; Tampere Medical School, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1016/j.acra.2013.09.018DOI Listing
January 2014

Diffusion Tensor Imaging in NAWM and NADGM in MS and CIS: Association with Candidate Biomarkers in Sera.

Mult Scler Int 2013 17;2013:265259. Epub 2013 Dec 17.

Neuroimmunology Unit, Medical School, University of Tampere, 33520 Tampere, Finland ; Department of Electronics and Communications Engineering, Tampere University of Technology, 33520 Tampere, Finland.

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http://dx.doi.org/10.1155/2013/265259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877634PMC
January 2014

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://dx.doi.org/10.1038/ng.2770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

Volumetric MRI assessment of brain and spinal cord in Finnish twins discordant for multiple sclerosis.

Medicina (Kaunas) 2012 ;48(9):437-41

Department of Neurology and Rehabilitation, Tampere University Hospital, Finland.

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September 2013

Melatonin pathway genes are associated with progressive subtypes and disability status in multiple sclerosis among Finnish patients.

J Neuroimmunol 2012 Sep 13;250(1-2):106-10. Epub 2012 Jun 13.

Neuroimmunology Unit, School of Medicine, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1016/j.jneuroim.2012.05.014DOI Listing
September 2012

Early treatment in multiple sclerosis.

Authors:
Irina Elovaara

J Neurol Sci 2011 Dec;311 Suppl 1:S24-8

Department of Neurology, Tampere University Hospital, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1016/S0022-510X(11)70005-3DOI Listing
December 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Intravenous immunoglobulins are a therapeutic option in the treatment of multiple sclerosis relapse.

Clin Neuropharmacol 2011 Mar-Apr;34(2):84-9

Neuroimmunology Unit, Medical School, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1097/WNF.0b013e31820a17f3DOI Listing
July 2011

Disease-associated inflammatory biomarker profiles in blood in different subtypes of multiple sclerosis: prospective clinical and MRI follow-up study.

J Neuroimmunol 2011 May 11;234(1-2):141-7. Epub 2011 Mar 11.

Neuroimmunology Unit, Medical School, University of Tampere and Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1016/j.jneuroim.2011.02.009DOI Listing
May 2011

Causes of death among patients with multiple sclerosis.

Mult Scler 2010 Dec 8;16(12):1437-42. Epub 2010 Sep 8.

Faculty of Medicine, University of Tampere, Finland.

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http://dx.doi.org/10.1177/1352458510379244DOI Listing
December 2010

Brain iron deposition and sequence characteristics in Parkinsonism: comparison of SWI, T₂* maps, T₂-weighted-, and FLAIR-SPACE.

Invest Radiol 2010 Dec;45(12):795-802

Department of Radiology, Medical Imaging Centre, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1097/RLI.0b013e3181ec9c96DOI Listing
December 2010

MRI texture analysis in multiple sclerosis: toward a clinical analysis protocol.

Acad Radiol 2010 Jun;17(6):696-707

Medical Imaging Center, Tampere University Hospital, Teiskontie 35, Tampere, Finland.

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http://dx.doi.org/10.1016/j.acra.2010.01.005DOI Listing
June 2010

[Stem cells in therapy of multiple sclerosis].

Duodecim 2009 ;125(9):965-73

Tampereen yliopisto, TAYS, Sekä Solu- ja kudosteknologiakeskus Regea, Biokatu, Tampere.

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July 2009

MYO9B polymorphisms in multiple sclerosis.

Eur J Hum Genet 2009 Jun 14;17(6):840-3. Epub 2009 Jan 14.

Department of Molecular Medicine, National Public Health Institute and Institute for Molecular Medicine Finland, FIMM, Helsinki, Finland.

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http://dx.doi.org/10.1038/ejhg.2008.251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685895PMC
June 2009

A follow-up study of chromosome 19q13 in multiple sclerosis susceptibility.

J Neuroimmunol 2009 Mar 4;208(1-2):119-24. Epub 2009 Feb 4.

Molecular Neuroscience Programme, Biomedicum-Helsinki, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jneuroim.2009.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682252PMC
March 2009

No evidence for shared etiology in two demyelinative disorders, MS and PLOSL.

J Neuroimmunol 2009 Jan 18;206(1-2):86-90. Epub 2008 Nov 18.

Finnish Institute for Molecular Medicine, FIMM, and National Public Health Institute, Biomedicum, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jneuroim.2008.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682253PMC
January 2009

Apoptosis-related molecules in blood in multiple sclerosis.

J Neuroimmunol 2008 Dec 28;205(1-2):135-41. Epub 2008 Oct 28.

Neuroimmunology Unit, Department of Neurology, Finn-Medi 3, Biokatu 10, 33014 University of Tampere, Finland.

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http://dx.doi.org/10.1016/j.jneuroim.2008.09.002DOI Listing
December 2008

[Not Available].

Duodecim 2006 ;122(18):2181-2

Maskun Neurologinen Kuntoutuskeskus, Masku.

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April 2008

[Not Available].

Duodecim 2006 ;122(18):2239-47

TAYS, neurologian ja kuntoutuksen vastuualue.

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April 2008

Cell surface adhesion molecules and cytokine profiles in primary progressive multiple sclerosis.

Mult Scler 2007 Jul 15;13(6):701-7. Epub 2007 Mar 15.

Department of Neurology, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1177/1352458506075378DOI Listing
July 2007

Elevated serum soluble vascular adhesion protein-1 (VAP-1) in patients with active relapsing remitting multiple sclerosis.

J Neuroimmunol 2006 Aug 30;177(1-2):132-5. Epub 2006 Jun 30.

Department of Neurology and MediCity Research Laboratory, University of Turku, PO Box 52, 20521Turku, Finland.

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http://dx.doi.org/10.1016/j.jneuroim.2006.05.014DOI Listing
August 2006

Gene expression profiles in Finnish twins with multiple sclerosis.

BMC Med Genet 2006 Feb 27;7:11. Epub 2006 Feb 27.

Neuroimmunology Unit, Department of Neurology, Tampere University Hospital, Teiskontie, 35, 33520 Tampere, Finland.

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http://dx.doi.org/10.1186/1471-2350-7-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421383PMC
February 2006

Fine mapping of the multiple sclerosis susceptibility locus on 5p14-p12.

J Neuroimmunol 2005 Dec 19;170(1-2):122-33. Epub 2005 Sep 19.

Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2005.08.004DOI Listing
December 2005

Suppression of immune system genes by methylprednisolone in exacerbations of multiple sclerosis. Preliminary results.

J Neurol 2004 Oct;251(10):1215-9

Tampere University Hospital, Centre for Laboratory Medicine, Laboratory of Atherosclerosis Genetics Finn-Medi 2, 3rd Floor, P. O. Box 2000, 33521 Tampere, Finland.

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http://dx.doi.org/10.1007/s00415-004-0516-yDOI Listing
October 2004

[Multiple sclerosis in a female patient].

Duodecim 2003 ;119(21):2037-43

Tampereen yliopisto, lääketieteen laitos.

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March 2004