Publications by authors named "Irfan Mohamad"

78 Publications

Traumatic Neck Injury: An Accidental Impalement by a Needlefish.

Wilderness Environ Med 2021 Aug 31. Epub 2021 Aug 31.

Borneo Marine Research Institute, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.

Encounters between marine animals and humans can result in critical injury and fatal complications. We highlight a 20-y-old male who sustained a penetrating injury to the neck as a result of impalement by needlefish (Tylosurus sp) while snorkeling. He sustained a penetrating injury in the posterior triangle of the neck. On presentation, he was stabilized and received empirical antibiotics, analgesia, and antitetanus toxoid injection before being transferred to a tertiary center. On presentation to the tertiary hospital, the patient was hemodynamically stable with no clinical evidence of injury to surrounding neck structures, and this was confirmed using computed tomography. The patient underwent local wound exploration and retrieval of the needlefish beak under general anesthesia. The wound was left open to heal by secondary intention. The patient was discharged with oral antibiotics and went on to make a complete recovery.
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http://dx.doi.org/10.1016/j.wem.2021.07.006DOI Listing
August 2021

The Role of Social Media in Making an Impact to Health Knowledge and Behaviour on COVID-19 in Malaysia.

Malays J Med Sci 2021 Jun 30;28(3):155-157. Epub 2021 Jun 30.

Islamic Medical Association of Malaysia (IMAM) Response and Relief Team (IMARET), Cheras, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.21315/mjms2021.28.3.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260071PMC
June 2021

Challenges and Adaptation in Otorhinolaryngology Practice During Pandemic Lockdown: Experience from a Malaysian COVID-19 Hospital.

Malays J Med Sci 2021 Jun 30;28(3):143-150. Epub 2021 Jun 30.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

COVID-19 has taken the world by storm: since the first few cases appeared in Wuhan, China in December 2019 and by June 2020 there were more than 10 million cases of COVID-19 cases worldwide. Malaysia had its first case in January 2020 and acted promptly by implementing several drastic measures to contain the disease. Subsequently, the Ministry of Health Malaysia has implemented guidelines and recommendations on the management of COVID-19. The Department of Otorhinolaryngology-Head and Neck Surgery (ORL-HNS) provides services for patients with ear, nose, throat, head and neck diseases and provides audiology, speech and language therapy, as well as undergraduate and postgraduate training. As the department's staff is heavily involved in examinations and interventions of upper aerodigestive tract problems, the challenges are distinctly different from other specialties. This article discusses how COVID-19 affected ORL-HNS services and what measures were taken in Hospital Melaka, Malaysia.
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http://dx.doi.org/10.21315/mjms2021.28.3.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260059PMC
June 2021

Managing supraglottitis in the COVID-19 era.

Vis J Emerg Med 2021 Jul 14;24:101092. Epub 2021 Jul 14.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kota Bharu, Kelantan 16150, Malaysia.

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http://dx.doi.org/10.1016/j.visj.2021.101092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277377PMC
July 2021

Primary Eustachian Tube Tuberculosis.

Medeni Med J 2021 18;36(2):172-175. Epub 2021 Jun 18.

Hospital Sultan Abdul Halim, Department of Otorhinolaryngology-Head & Neck Surgery, Sungai Petani, Kedah, Malaysia.

Nasopharyngeal tuberculosis is a rare occurrence, and primarily involves the proximal part of the Eustachian tube. Mechanical obstruction of the Eustachian tube will affect the pressure discrepancy between the middle ear and the external atmosphere, leading to aural fullness, unilateral hearing disturbance, and otitis media. These conditions can be overlooked or mistakenly diagnosed as ear pathology. We report a case of unilateral hearing loss and tinnitus in a 31-year-old healthy woman that was later confirmed to be tuberculosis of the Eustachian tube. In cases with indicators suggesting a high index of suspicion, a thorough examination of the head and neck regions is especially very important. Once it has been diagnosed, Eustachian tuberculosis can be successfully treated with anti-tuberculosis medications.
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http://dx.doi.org/10.5222/MMJ.2021.52460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226409PMC
June 2021

Acute Retropharyngeal Calcific Tendonitis as a Rare Cause of Odynophagia and Neck Pain.

Medeni Med J 2021 26;36(1):75-79. Epub 2021 Mar 26.

Universiti Sains Malaysia, School of Medical Sciences, Department of Otorhinolaryngology- Head and Neck Surgery, Kelantan, Malaysia.

Retropharyngeal calcific tendonitis (RCT) is an aseptic inflammatory process of the superior oblique tendons of the longus colli muscle caused by the deposition of calcium hydroxyapatite crystals. We reported a 23-year-old woman who presented with a sudden onset of neck pain with odynophagia after waking up from sleep. Physical examination showed paracervical point tenderness with limited neck movement in all directions. Prior to surgery, further imaging was requested to aid in diagnosis, which in turn revealed RCT. It is important to be aware that RCT presentation may mimic other severe conditions such as retropharyngeal space abscess or meningitis.
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http://dx.doi.org/10.5222/MMJ.2021.37539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020188PMC
March 2021

Purulent Discharge on the Pharyngeal Wall.

Oman Med J 2021 Jan 31;36(1):e228. Epub 2021 Jan 31.

Medical Based Department, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.

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http://dx.doi.org/10.5001/omj.2021.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883409PMC
January 2021

Real-time loop-mediated isothermal amplification assay for rapid detection of human papillomavirus 16 in oral squamous cell carcinoma.

Arch Oral Biol 2021 Apr 28;124:105051. Epub 2021 Jan 28.

School of Dental Sciences, Universiti Sains Malaysia, Health Campus, 16150, Kubang Kerian, Kelantan, Malaysia. Electronic address:

Objective: The present study established a real-time loop-mediated isothermal amplification (qLAMP) for rapid detection of human papillomavirus subtype 16 (HPV-16) in oral squamous cell carcinoma (OSCC).

Methods: The qLAMP assay was optimized targeting the HPV-16 E7 gene. The analytical sensitivity and specificity of the assay were determined using HPV-18 (ATCC® 45152D™), HPV-35 (ATCC® 40330™), HPV-43 (ATCC® 40338™) and HPV-56 (ATCC® 40549™) viral strains and oral bacteria. HPV-16 standard curve was constructed for determination of HPV-16 viral load. The diagnostic performance of the assay was evaluated from 63 OSCC patients comprising 63 tissue, 13 saliva and 49 blood samples, in comparison with p16 immunohistochemistry (IHC), in-house PCR and nested PCR assays.

Results: The detection limit of developed LAMP and PCR assays was 4.68 × 10 and 4.68 × 10 copies/μl, respectively. qLAMP assay enabled detection of positive results as early as 23 min at 67 °C. This assay can detect HPV-16 positivity in 23 % (3/13) saliva and 4.8 % (3/63) tissue samples with the viral load ranging from 4.68 × 10 to 4.68 × 10 copies/μl. HPV-16 positivity was not detected in all the blood samples. The sensitivity and specificity of qLAMP were 100 % in comparison with that of p16 IHC and nested PCR.

Conclusion: This study reports for the first time on the use of qLAMP assay for detection of HPV-16 in OSCC in both tissue and saliva as the sample matrix which holds promise in improving the diagnostic application owing to its rapidity, simplicity, high sensitivity and specificity.
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http://dx.doi.org/10.1016/j.archoralbio.2021.105051DOI Listing
April 2021

Basaloid Nasopharyngeal Carcinoma: An Entity That Remains Oblivious.

Gulf J Oncolog 2020 Sep;1(34):83-86

Department of Otorhinolaryngology, Hospital Tuanku Ja'afar, Jalan Rasah, 70300 Seremban, Negeri Sembilan, Malaysia.

Introduction: Basaloid squamous cell carcinoma of the nasopharynx is a rare entity with only scarce cases reported in the English Literature. It is a histological variant of squamous cell carcinoma with aggressive nature and comprises of both basal cell carcinoma and squamous cell carcinoma.

Case Presentation: Herein, we report on a middleaged male who presented with left-sided spontaneous epistaxis and aural fullness with no neck node which turned out to be basaloid cell carcinoma of nasopharynx.

Discussion And Conclusion: We highlight high clinical suspicion of rare variant of nasopharyngeal carcinoma although no palpable node was evident upon presentation.
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September 2020

Posterior Ethmoid Nodular Fasciitis.

Medeni Med J 2020 30;35(3):276-280. Epub 2020 Sep 30.

Department of Pathology, Hospital Raja Perempuan Zainab II, Kota Bharu, Kelantan, Malaysia.

Nodular fasciitis (NF) is an uncommon and benign tumour-like fibroblastic proliferation that is difficult to distinguish from sarcoma both clinically and histologically. In addition, it is a type of lesion characterised by having a potential for spontaneous regression. NF is frequently misdiagnosed due to its rapid growth, rich cellularity, and mitotic figure. Although NF is only rarely diagnosed in children, the head and neck represent the most common locations for NF among this population. The cause of NF remains unknown, however trauma is believed to be an important triggering factor. We describe an unusual case of NF in the posterior ethmoid sinus in a six-year-old boy with no history of trauma. The NF was incidentally noted on a computed tomography scan after the patient complained of a squint. The diagnosis of NF was also supported by histopathology and specific immunohistological staining. A surgical biopsy was performed, and no recurrence was observed after one year.
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http://dx.doi.org/10.5222/MMJ.2020.90093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584270PMC
September 2020

Vocal Fold Injury Following Intubation.

J Craniofac Surg 2020 10;31(7):2064-2065

Speech Pathology Programme, School of Health Sciences, Universiti Sains Malaysia Health Campus, Kota Bharu, Malaysia.

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http://dx.doi.org/10.1097/SCS.0000000000006839DOI Listing
October 2020

MJMS Performance Reports 2014-2018: The Unique Profile of the Top Submitting Authors.

Authors:
Irfan Mohamad

Malays J Med Sci 2020 Mar 30;27(2):170-171. Epub 2020 Apr 30.

Department of Otorhinolaryngology - Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

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http://dx.doi.org/10.21315/mjms2020.27.2.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409572PMC
March 2020

The Insights of Head and Neck Non-Hodgkin Lymphoma.

Medeni Med J 2020 30;35(2):179-180. Epub 2020 Jun 30.

Universiti Sains Malaysia, School of Medical Sciences, Department of Otorhinolaryngology- Head & Neck Surgery, Kota Bharu, Kelantan, Malaysia.

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http://dx.doi.org/10.5222/MMJ.2020.23682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384514PMC
June 2020

Kimura Disease with Parotid Swelling and Cervical Lymphadenopathy: A Case Report and Literature Review.

Medeni Med J 2020 30;35(2):170-174. Epub 2020 Jun 30.

Universiti Sains Malaysia Health Campus, School of Medical Sciences, Department of Otorhinolaryngology-Head and Neck Surgery, Kelantan, Malaysia.

Kimura disease (KD) is a rare chronic benign inflammatory disorder of unknown etiology that is prevalent in Asian males. The head and neck region, especially the parotid glands and cervical lymph nodes, are most commonly affected. Diagnosis is based on clinicopathological features, while radiology findings are nonspecific. Although various treatment strategies have been proposed, there is a high recurrence rate. Combination therapy has been found to produce better results than monotherapy. We present a case of KD with huge parotid and cervical lymph node involvement that was treated with a combination of surgery and corticosteroids administered perioperatively.
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http://dx.doi.org/10.5222/MMJ.2020.84594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384504PMC
June 2020

Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia.

Medeni Med J 2020 30;35(2):166-169. Epub 2020 Jun 30.

Universiti Sains Malaysia, Health Campus, School of Dental Sciences, Kelantan, Malaysia.

Carcinosarcoma is a rare type of malignant tumour that possess both the elements of carcinoma and sarcoma. They may occur in various locations such as the uterus, breast, thyroid, lung and gastrointestinal system. However, very few primary mediastinal carcinosarcomas have been reported. We are presenting a case of a 75-year-old male who presented with progressive dysphagia and hoarseness for 3 weeks. Contrast-enhanced computed tomography of the neck showed features of enlarged mediastinal necrotic nodes and the biopsy of this mass showed morphology and immunohistochemical profile that are consistent with carcinosarcoma. However, the patient succumbed to his illness soon after diagnosis.
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http://dx.doi.org/10.5222/MMJ.2020.82956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384507PMC
June 2020

Ex Utero Intrapartum Treatment (Exit) of Gigantic Intrapartum Lymphangioma and Its Management Dilemma - A Case Report.

Medeni Med J 2020 30;35(2):161-165. Epub 2020 Jun 30.

Universiti Sains Malaysia, Health Campus, School of Medical Sciences, Department of Otorhinolaryngology-Head & Neck Surgery, Kota Bharu, Kelantan, Malaysia.

With the advancement of radiological investigation, intrapartum detection of fetal abnormalities is now precisely performed. Lymphangiomas are now diagnosed even before patient is born. The swelling may be gigantic and potentially life-threatening during the delivery. Nowadays, it is still a great challenge to doctors as how to deliver the baby together with the big neck mass. We present a case of huge intrapartum neck lymphangioma, for which we performed ex-utero intrapartum treatment (EXIT) procedure, followed by excision of the lesion later. The challenges on managing both mother and infant will be discussed.
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http://dx.doi.org/10.5222/MMJ.2020.06992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384513PMC
June 2020

Mantle Cell Lymphoma: A Rare Vallecular Tumour.

Medeni Med J 2020 28;35(1):67-70. Epub 2020 Feb 28.

Universiti Sains Malaysia, School of Medical Sciences, Department of Pathology, Kubang Kerian, Malaysia.

Vallecular lymphoma is an extremely rare tumour of oropharynx. We report a case of 61-year-old gentleman presented with severe dysphagia and globus sensation for two months. Patient underwent endoscopic transoral tumour debulking for diagnostic and therapeutic purpose. Histopathologically, patient was diagnosed as mantle cell lymphoma (MCL). In this case report, atypical presentation of the disease, histopathological features and its current treatments are discussed.
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http://dx.doi.org/10.5222/MMJ.2020.22208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384489PMC
February 2020

When Air is the Complication: Emphysema Following Tracheostomy.

Authors:
Irfan Mohamad

Oman Med J 2020 May 30;35(3):e139. Epub 2020 Jun 30.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

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http://dx.doi.org/10.5001/omj.2020.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372390PMC
May 2020

Managing Aerodigestive Emergencies During the COVID-19 Pandemic: Challenges for Healthcare Workers.

Malays J Med Sci 2020 May 30;27(3):153-156. Epub 2020 Jun 30.

Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

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http://dx.doi.org/10.21315/mjms2020.27.3.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337941PMC
May 2020

Sustainable Medical Teaching and Learning During the COVID-19 Pandemic: Surviving the New Normal.

Malays J Med Sci 2020 May 30;27(3):137-142. Epub 2020 Jun 30.

Department of Community Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

During the first phase of the Movement Control Order, many medical lecturers had difficulty adapting to the online teaching and learning methods that were made compulsory by the institutional directives. Some of these lecturers are clinicians who need to juggle between clinical work and teaching, and consider a two-week adaptation during this period to be not enough. Furthermore, converting traditional face-to-face learning to online formats for undergraduate and postgraduate clinical programmes would reduce the learning outcomes, especially those related to clinical applications and the acquisition of new skills. This editorial discusses the impact that movement restrictions have had on medical teaching and learning, the alternatives and challenges and the way forward.
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http://dx.doi.org/10.21315/mjms2020.27.3.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337950PMC
May 2020

Giant submandibular sialolipoma masquerading as huge goitre: a case report.

BMC Surg 2020 Jun 11;20(1):130. Epub 2020 Jun 11.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.

Background: Sialolipoma is a rare tumour which may arise from both major and minor salivary glands and has recently been described as a variant of salivary gland lipomatous lesions.

Case Presentation: We report a 54-year-old male who presented with a 7-year history of large right anterior neck swelling. He was clinically euthyroid and had no compressive or infiltrative symptoms. He sought medical attention due to the discomfort exerted by the weight of the mass and was keen for excision. The swelling appeared like a goitre but physical examination proved otherwise. Imaging was suggestive of a benign tumour arising from the right parapharyngeal fossa. The mass was surgically excised and was noted to be adherent to part of the submandibular gland. Histopathological examination revealed a new variant of benign adipocytic tumour of salivary gland or sialolipoma arising from the submandibular gland. Besides being the largest sialolipoma to be reported, there are also no reports of giant submandibular sialolipomas masquerading as a huge goitre in appearance.

Conclusion: Submandibular sialolipomas can present in really large sizes and appear as a giant goitre. It is important to differentiate between benign lipomas from liposarcomas and tailor the management accordingly. Surgical enucleation is the preferred choice of treatment for these benign tumours with low recurrence rates.
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http://dx.doi.org/10.1186/s12893-020-00787-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291645PMC
June 2020

Bilateral Vocal Cord Immobility After Chemoradiotherapy For Nasopharyngeal Carcinoma.

Gulf J Oncolog 2020 May;1(33):80-83

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, Kubang Kerian, Kelantan, Malaysia.

Post chemoradiation vocal cord immobility is a rare complication and this maybe life threatening when patients present with severe aspiration and recurrent pneumonia or even worse if they have an upper airway obstruction. We report a case of nasopharyngeal carcinoma patient whom after receiving curative concurrent chemoradiotherapy, presented with episodes of shortness of breath and aspiration pneumonia finally diagnosed with bilateral vocal cord immobility. She had no evidence of tumour recurrence.
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May 2020

A Critical Appraisal of COVID-19 in Malaysia and Beyond.

Malays J Med Sci 2020 Mar 10;27(2):1-9. Epub 2020 Apr 10.

Editorial Board Member, Malaysian Journal of Medical Sciences, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

When the first report of COVID-19 appeared in December 2019 from Wuhan, China, the world unknowingly perceived this as another flu-like illness. Many were surprised at the extreme steps that China had subsequently taken to seal Wuhan from the rest of the world. However, by February 2020, the SARS-CoV-2 virus, which causes COVID-19, had spread so quickly across the globe that the World Health Organization officially declared COVID-19 a pandemic. COVID-19 is not the first pandemic the world has seen, so what makes it so unique in Malaysia, is discussed to avoid a future coronacoma.
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http://dx.doi.org/10.21315/mjms2020.27.2.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153689PMC
March 2020

A Rare Intraorbital Mass: An Isolated Mucocele.

Medeni Med J 2020 25;35(4):344-348. Epub 2020 Dec 25.

Universiti Sains Malaysia, School of Medical Sciences, Department of Otorhinolaryngology-Head and Neck Surgery, Kelantan, Malaysia.

Mucocele is a mucous filled benign cystic lesion. It develops due to obstruction of any natural os-tium of the paranasal sinus. Even though being benign, it has capability to erode and cause thinning the adjacent bony structures. Isolated intraorbital mucocele without paranasal sinus disease is a rare condition. We present a 39-year-old female patient with right medial canthal swelling without any nasal symptoms, and normal nasoendoscopic finding. Imaging revealed the lesion as a right ethmoidal mucocele with normal paranasal sinuses. However intraoperatively, it was an isolated intraorbital lesion, lateral to lamina papyracea with thick-yellowish mucin discharge.
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http://dx.doi.org/10.5222/MMJ.2020.01057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945724PMC
December 2020

Nasal NK/T-cell Lymphoma Presenting as Acute Inflammation of Nasal Vestibule.

Indian J Otolaryngol Head Neck Surg 2019 Nov 19;71(Suppl 3):1986-1989. Epub 2018 May 19.

Department of Otorhinolaryngology-Head & Neck Surgery, Hospital Tawau, 91007 Tawau, Malaysia.

Extra nodal nasal NK/T cell lymphoma is relatively a rare type of non-Hodgkin lymphoma. Variable clinical presentation with rapidly progressive necrosis of the cartilaginous and bony wall of the nose and upper respiratory passages leads to delayed diagnosis and treatment. A 43-years-old patient presented with right nasal pain and furuncle-like swelling. The swelling progressed rapidly to cellulitis to the face up to the right eye. Within 2 months, it had advanced to necrosis of the lateral vestibular cartilage, medial maxillary wall, turbinate and nasal septal cartilage. Biopsy reported as non-Hodgkin diffuse T cell (angiocentric T cell) lymphoma.
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http://dx.doi.org/10.1007/s12070-018-1402-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848314PMC
November 2019

Foreign Body Ingestion in Children: The Role of X-ray.

Authors:
Irfan Mohamad

Oman Med J 2019 Nov;34(6):570

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kelantan, Malaysia.

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http://dx.doi.org/10.5001/omj.2019.104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851070PMC
November 2019

Adult and Pediatric Lateral Lamella Cribriform Plate Height: In Need for a Comparative Study.

Allergy Rhinol (Providence) 2019 Jan-Dec;10:2152656719874775. Epub 2019 Sep 9.

Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.

Surgery for sinuses has evolved with the advancement of instruments and modification in techniques. Endoscopes have expanded the surgical roles for lesions in the nose and para-nasal sinuses with reduced rate of complications and cosmetic side effects. Nevertheless sinus surgery in pediatrics patients has its own challenges. Pre-operative imaging is of paramount important especially when embarking on skull base procedures. The differences between adult and pediatric anatomy need to be further studied.
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http://dx.doi.org/10.1177/2152656719874775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737862PMC
September 2019

"Double Tongue" Appearance in Ludwig's Angina.

N Engl J Med 2019 Jul;381(2):163

Hospital Sultanah Nora Ismail, Batu Pahat, Malaysia.

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http://dx.doi.org/10.1056/NEJMicm1814117DOI Listing
July 2019

Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity.

Oman Med J 2019 Jan;34(1):74-77

Department of Otorhinolaryngology-Head and Neck Surgery, Universiti Sains Malaysia Health Campus, Kelantan, Malaysia.

Mantle cell lymphoma (MCL) is a rare, aggressive subtype of non-Hodgkin lymphoma with a poor prognosis and high recurrence rate. It seldom affects the Waldeyer's ring let alone the nasopharynx. Patients usually present at late stages of the disease leading to poor failure-free and overall survival rates. Intensive chemotherapy regimes and autologous stem cell transplantation have reported increased survival rates. We report a relapsed case of nasopharyngeal MCL, which previously occurred in the gastrointestinal tract. The patient had undergone a hemicolectomy for colon intussusception secondary to the intraluminal lymphoma mass. He was unable to complete the treatment regime for MCL due to the adverse side effects. Oropharyngeal mass was discovered during routine outpatient follow-up, which was confirmed as nasopharyngeal MCL. We discuss the prognosis, disease progression, and possible treatments.
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http://dx.doi.org/10.5001/omj.2019.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330188PMC
January 2019

Aspiration Avoiding Tracheostomy in Neonatal Cystic Oral Lesion.

Medeni Med J 2019 26;34(4):400-403. Epub 2019 Dec 26.

Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia.

Oral cyst is uncommon in the neonatal period. Depending on the size and site of occurrence, its symptoms may vary. If not diagnosed and managed expeditiously, these oral cysts may cause significant and potentially fatal morbidity and mortality. We report a successfully managed case of oral cyst in neonate that presented with huge tongue at birth and complaints of impending airway obstruction. She was referred for tracheostomy as intubation was impossible. We attempted needle aspiration and the airway successfully relieved without the need for tracheostomy.
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http://dx.doi.org/10.5222/MMJ.2019.44977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433721PMC
December 2019
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