Irfan A Asangani

Irfan A Asangani

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Irfan A Asangani

Irfan A Asangani

Publications by authors named "Irfan A Asangani"

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31Publications

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EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins.

Cancer Res 2018 Aug 13;78(16):4760-4773. Epub 2018 Jun 13.

Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, BRBII/III, Philadelphia, Pennsylvania.

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August 2018

Resistance to BET Inhibitor Leads to Alternative Therapeutic Vulnerabilities in Castration-Resistant Prostate Cancer.

Cell Rep 2018 Feb;22(9):2236-2245

Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Cancer Biology, Abramson Family Cancer Research Institute, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, 421 Curie Boulevard, BRBII/III, Philadelphia, PA 19104, USA. Electronic address:

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February 2018

The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division.

Sci Signal 2018 Jan 2;11(511). Epub 2018 Jan 2.

Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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January 2018

Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer.

Cancer Cell 2017 04 23;31(4):532-548.e7. Epub 2017 Mar 23.

Michigan Center for Translational Pathology, University of Michigan, 1400 East Medical Center Drive, 5316 CCGC, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, 1400 East Medical Center Drive, 5316 CCGC, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, 1400 East Medical Center Drive, 5316 CCGC, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan, 1400 East Medical Center Drive, 5316 CCGC, Ann Arbor, MI 48109, USA; Comprehensive Cancer Center, University of Michigan, 1400 East Medical Center Drive, 5316 CCGC, Ann Arbor, MI 48109, USA. Electronic address:

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April 2017

BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer.

Mol Cancer Res 2016 04 20;14(4):324-31. Epub 2016 Jan 20.

Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan. Department of Pathology, University of Michigan, Ann Arbor, Michigan. Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan. Department of Urology, University of Michigan, Ann Arbor, Michigan.

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April 2016

Targeting the MLL complex in castration-resistant prostate cancer.

Nat Med 2015 Apr 30;21(4):344-52. Epub 2015 Mar 30.

1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA. [3] Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. [5] Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, USA. [6] Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.

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April 2015

Galanin modulates the neural niche to favour perineural invasion in head and neck cancer.

Nat Commun 2015 Apr 28;6:6885. Epub 2015 Apr 28.

1] Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan 48109, USA [2] Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [3] Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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April 2015

BETting on a new prostate cancer treatment.

Cell Cycle 2014 6;13(13):2015-6. Epub 2014 Jun 6.

Michigan Center for Translational Pathology; University of Michigan Medical School; Ann Arbor, MI USA; Department of Pathology; University of Michigan Medical School; Ann Arbor, MI USA; Howard Hughes Medical Institute; University of Michigan Medical School; Ann Arbor, MI USA; Comprehensive Cancer Center; University of Michigan Medical School; Ann Arbor, MI USA; Department of Urology; University of Michigan Medical School; Ann Arbor, MI USA.

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January 2015

BETs abet Tam-R in ER-positive breast cancer.

Cell Res 2014 Aug 8;24(8):899-900. Epub 2014 Jul 8.

1] Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA [2] Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA [3] Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA [4] Department of Urology, University of Michigan Medical School, Ann Arbor, MI 48109, USA [5] Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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August 2014

The lncRNA PCAT29 inhibits oncogenic phenotypes in prostate cancer.

Mol Cancer Res 2014 Aug 16;12(8):1081-7. Epub 2014 Jul 16.

Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan. Department of Pathology, University of Michigan, Ann Arbor, Michigan. Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan.

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August 2014

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.

Nature 2014 Jun 23;510(7504):278-82. Epub 2014 Apr 23.

1] Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [2] Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [3] Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [4] Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [5] Department of Urology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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June 2014

Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer.

Biosci Rep 2011 Jun;31(3):185-97

Department of Experimental Surgery, Mannheim Medical Faculty, Ruprecht-Karls-University Heidelberg, 68167 Mannheim, Germany.

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June 2011

Cetuximab attenuates metastasis and u-PAR expression in non-small cell lung cancer: u-PAR and E-cadherin are novel biomarkers of cetuximab sensitivity.

Cancer Res 2009 Mar 10;69(6):2461-70. Epub 2009 Mar 10.

Department of Experimental Surgery and Molecular Oncology of Solid Tumors, Medical Faculty Mannheim, University Heidelberg and DKFZ (German Cancer Research Center), Heidelberg, Germany.

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March 2009

NRF-1, and AP-1 regulate the promoter of the human calpain small subunit 1 (CAPNS1) gene.

Gene 2008 Feb 23;410(1):197-206. Epub 2007 Dec 23.

Department Experimental Surgery Mannheim, University Heidelberg, and Molecular Oncology of Solid Tumors Unit, German Cancer Research Center (DKFZ) Heidelberg, Germany.

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February 2008

Combination analysis of activator protein-1 family members, Sp1 and an activator protein-2alpha-related factor binding to different regions of the urokinase receptor gene in resected colorectal cancers.

Clin Cancer Res 2005 Dec;11(24 Pt 1):8538-48

Department of Experimental Surgery and Molecular Oncology, Universitaetsklinikum Mannheim and Department of Pediatrics, Dr. v. Haunersches Kinderspital, Munich, Germany.

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December 2005