Irene Lee

Irene Lee

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Irene Lee

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PromISR-6, a Guanabenz Analogue, Improves Cellular Survival in an Experimental Model of Huntington's Disease.

ACS Chem Neurosci 2019 Aug 30;10(8):3575-3589. Epub 2019 Jul 30.

National Neuroscience Institute of Singapore , 11 Jalan Tan Tock Seng , Singapore 308433.

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http://dx.doi.org/10.1021/acschemneuro.9b00185DOI Listing
August 2019

Active Cushing Disease Is Characterized by Increased Adipose Tissue Macrophage Presence.

J Clin Endocrinol Metab 2019 Jun;104(6):2453-2461

Division of Endocrinology, Metabolism and Diabetes, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1210/jc.2018-02552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510019PMC
June 2019

Fovea-sparing rhegmatogenous retinal detachments: impact of clinical factors including time to surgery on visual and anatomic outcomes.

Graefes Arch Clin Exp Ophthalmol 2019 May 11;257(5):883-889. Epub 2019 Jan 11.

Retina Consultants of Houston, 6560 Fannin Street, Suite 750, Houston, TX, 77030, USA.

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http://link.springer.com/10.1007/s00417-018-04236-4
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http://dx.doi.org/10.1007/s00417-018-04236-4DOI Listing
May 2019

Bag-1L: a promising therapeutic target for androgen receptor-dependent prostate cancer.

J Mol Endocrinol 2019 Mar 1. Epub 2019 Mar 1.

A Cato, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany.

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http://dx.doi.org/10.1530/JME-19-0034DOI Listing
March 2019

Risk Factors for Early Intraocular Pressure Elevation After Cataract Surgery in a Cohort of United States Veterans.

Mil Med 2018 Sep;183(9-10):e427-e433

Section of Ophthalmology, VA Medical Center, 830 Chalkstone Ave, Providence, RI.

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http://dx.doi.org/10.1093/milmed/usx113DOI Listing
September 2018

Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function.

Cell Death Differ 2018 02 6;25(2):255-267. Epub 2017 Oct 6.

Signature Research Programmes in Neuroscience and Behavioural Disorders, and Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, Singapore.

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http://dx.doi.org/10.1038/cdd.2017.152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762841PMC
February 2018

Inactivation of bovine plasma amine oxidase by 1,1,1-trihalo-3-aminopropanes.

Bioorg Chem 2017 12 16;75:265-273. Epub 2017 Oct 16.

Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.bioorg.2017.10.007DOI Listing
December 2017

Evaluating social (pragmatic) communication disorder.

J Child Psychol Psychiatry 2017 Oct 25;58(10):1166-1175. Epub 2017 Jul 25.

Behavioural and Brain Science Unit, Institute of Child Health, UCL, London, UK.

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http://dx.doi.org/10.1111/jcpp.12785DOI Listing
October 2017

Dysfunction of mitochondrial Lon protease and identification of oxidized protein in mouse brain following exposure to MPTP: Implications for Parkinson disease.

Free Radic Biol Med 2017 07 30;108:236-246. Epub 2017 Mar 30.

INSERM, U1127, The Brain and Spinal Cord Institute (ICM), Hôpital de la Salpêtrière, 75013 Paris, France; CNRS, UMR 7225, Centre de Recherche en neurosciences, ICM, Thérapeutique expérimentale de la neurodégénérescence, Hôpital de la Salpêtrière, Paris, F-75005 Paris, France; Sorbonne Universités, Université Pierre et Marie Curie, 75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.03.036DOI Listing
July 2017

Utilization of Mechanistic Enzymology to Evaluate the Significance of ADP Binding to Human Lon Protease.

Front Mol Biosci 2017 11;4:47. Epub 2017 Jul 11.

Department of Chemistry, Case Western Reserve UniversityCleveland, OH, United States.

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http://dx.doi.org/10.3389/fmolb.2017.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504276PMC
July 2017

Considering Cocreation for the Choosing Wisely List.

Acad Med 2017 05;92(5):576

Medical student, Icahn School of Medicine at Mount Sinai, New York, New York; Medical student, Icahn School of Medicine at Mount Sinai, New York, New York. Director of quality and patient safety and assistant professor of medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://Insights.ovid.com/crossref?an=00001888-201705000-0001
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http://dx.doi.org/10.1097/ACM.0000000000001644DOI Listing
May 2017

Arousal Rules: An Empirical Investigation into the Aesthetic Experience of Cross-Modal Perception with Emotional Visual Music.

Front Psychol 2017 4;8:440. Epub 2017 Apr 4.

Communicative Interaction Lab, Graduate School of Culture Technology, Korea Advanced Institute of Science and TechnologyDaejeon, South Korea.

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http://dx.doi.org/10.3389/fpsyg.2017.00440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379063PMC
April 2017

External dacryocystorhinostomy outcomes in patients with a history of dacryocystitis.

Digit J Ophthalmol 2015 20;21(3):1-22. Epub 2015 Sep 20.

Division of Ophthalmic Plastic Surgery, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts;; Department of Ophthalmology, Harvard Medical School, Boston;

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http://dx.doi.org/10.5693/djo.01.2014.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902648PMC
March 2017

Translating protein phosphatase research into treatments for neurodegenerative diseases.

Biochem Soc Trans 2017 02;45(1):101-112

Signature Programs in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, Singapore

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http://dx.doi.org/10.1042/BST20160157DOI Listing
February 2017

Regulation of Pyruvate Dehydrogenase Kinase 4 in the Heart through Degradation by the Lon Protease in Response to Mitochondrial Substrate Availability.

J Biol Chem 2017 Jan 17;292(1):305-312. Epub 2016 Nov 17.

From the Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104,

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http://dx.doi.org/10.1074/jbc.M116.754127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217688PMC
January 2017

Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response.

Mol Cell Biol 2016 07 15;36(13):1868-80. Epub 2016 Jun 15.

Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, Singapore Signature Research Program in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, Singapore, Singapore

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http://dx.doi.org/10.1128/MCB.00190-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911741PMC
July 2016

Effect on Baby-Friendly Hospital Steps When Hospitals Implement a Policy to Pay for Infant Formula.

J Hum Lact 2016 May 18;32(2):238-49. Epub 2015 Aug 18.

College of Nursing and Healthcare Innovation, Arizona State University, AZ, USA.

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http://dx.doi.org/10.1177/0890334415599399DOI Listing
May 2016

The Mental Health of Older Persons After Human-Induced Disasters: A Systematic Review and Meta-Analysis of Epidemiological Data.

Am J Geriatr Psychiatry 2016 05 8;24(5):379-88. Epub 2016 Jan 8.

School of Medicine, University of Queensland, Brisbane, Australia; Metro South Addiction and Mental Health Service, Brisbane, Australia; Diamantina Health Partners: Centre for Neuroscience Recovery and Mental Health, Brisbane, Australia; Griffith Institute of Health, Griffith University, Brisbane, Australia.

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http://dx.doi.org/10.1016/j.jagp.2015.12.010DOI Listing
May 2016

Exploiting Aryl Mesylates and Tosylates in Catalytic Mono-α-arylation of Aryl- and Heteroarylketones.

Org Lett 2016 Apr 5;18(8):1872-5. Epub 2016 Apr 5.

State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University , Hung Hom, Kowloon, Hong Kong.

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http://dx.doi.org/10.1021/acs.orglett.6b00643DOI Listing
April 2016

Physiological enzymology: The next frontier in understanding protein structure and function at the cellular level.

Biochim Biophys Acta 2016 Jan 13;1864(1):65-9. Epub 2015 Aug 13.

Department of Chemistry, Cleveland State University, 2351 Euclid Avenue, Cleveland, OH 44115, USA; Center for Gene Regulation in Health and Disease, Cleveland State University, 2351 Euclid Avenue, Cleveland, OH 44115, USA; Case Comprehensive Cancer Center, 11000 Euclid Avenue, Cleveland, OH 44106, USA; Red5 Pharmaceuticals, LLC, 10000 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2015.07.011DOI Listing
January 2016

Strategies and techniques to understand the structure and function of proteins inside cells.

Biochim Biophys Acta 2016 Jan 25;1864(1):62-3. Epub 2015 Sep 25.

Department of Chemistry, Cleveland State University, 2351 Euclid Avenue, Cleveland, OH 44115, USA; Center for Gene Regulation in Health and Disease, Cleveland State University, 2351 Euclid Avenue, Cleveland, OH 44115, USA; Case Comprehensive Cancer Center, 11000 Euclid Avenue, Cleveland, OH 44106, USA; Red5 Pharmaceuticals, LLC, 10000 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2015.09.003DOI Listing
January 2016

Effect of a hospital policy of not accepting free infant formula on in-hospital formula supplementation rates and breast-feeding duration.

Public Health Nutr 2015 Oct 27;18(14):2689-99. Epub 2015 Feb 27.

7College of Nursing and Healthcare Innovation,Arizona State University,Phoenix,AZ,USA.

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http://dx.doi.org/10.1017/S1368980015000117DOI Listing
October 2015

Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.

Cell Rep 2015 Jun 18;11(12):1885-91. Epub 2015 Jun 18.

Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI 02912, USA; Department of Chemistry, Brown University, Providence, RI 02912, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489983PMC
June 2015

Interdisciplinary medical social work: a working taxonomy.

Soc Work Health Care 2014 ;53(6):532-51

a Simmons College School of Social Work, Harvard School of Dental Medicine , Harvard School of Public Health , Boston , Massachusetts , USA.

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http://dx.doi.org/10.1080/00981389.2014.905817DOI Listing
April 2015

Synaptic, transcriptional and chromatin genes disrupted in autism.

Antenatal education to increase exclusive breastfeeding: a randomized controlled trial.

Obstet Gynecol 2014 Nov;124(5):961-8

School of Nursing, the University of Hong Kong, and Queen Mary Hospital, Pokfulam, and Kwong Wah Hospital, Kowloon, Hong Kong.

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http://dx.doi.org/10.1097/AOG.0000000000000481DOI Listing
November 2014

Influence of AKT on progesterone action in endometrial diseases.

Biol Reprod 2014 Sep 6;91(3):63. Epub 2014 Aug 6.

Division of Reproductive Science in Medicine, Department of Obstetrics and Gynecology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois

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http://dx.doi.org/10.1095/biolreprod.114.119255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435059PMC
September 2014

Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics.

J Biol Chem 2014 Sep 8;289(39):26989-7003. Epub 2014 Aug 8.

From the Institute of Molecular and Cell Biology, A-STAR, 61 Biopolis Drive, Singapore 138673 and

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http://dx.doi.org/10.1074/jbc.M114.588079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175338PMC
September 2014

Effect of solvent on diffusion: probing with nonpolar solutes.

J Phys Chem B 2014 Sep 9;118(37):10945-55. Epub 2014 Sep 9.

Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University , Hung Hom, Kowloon, Hong Kong.

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http://dx.doi.org/10.1021/jp505141zDOI Listing
September 2014

Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills.

Proc Natl Acad Sci U S A 2014 Feb 23;111(5):1987-92. Epub 2013 Dec 23.

Institute of Child Health, University College London, London WC1N 1EH, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1302985111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918840PMC
February 2014

Development and characterization of a non-natural nucleoside that displays anticancer activity against solid tumors.

ACS Chem Biol 2013 Nov 16;8(11):2452-65. Epub 2013 Sep 16.

Departments of Pharmacology and ‡Chemistry, Case Western Reserve University , 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.

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http://dx.doi.org/10.1021/cb400350hDOI Listing
November 2013

Fall Prevention for Community-Living Older Adults: A Tale of Two Systematic Reviews.

OT Pract 2013 Sep;18(16):19-22

The University of Southern California's Division of Occupational Science and Occupational Therapy and the Davis School of Gerontology.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351703PMC
September 2013

Processive degradation of unstructured protein by Escherichia coli Lon occurs via the slow, sequential delivery of multiple scissile sites followed by rapid and synchronized peptide bond cleavage events.

Biochemistry 2013 Aug 24;52(33):5629-44. Epub 2013 Jul 24.

Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1021/bi4008319DOI Listing
August 2013

Insights into the roles of desolvation and π-electron interactions during DNA polymerization.

Chembiochem 2013 Mar 12;14(4):489-98. Epub 2013 Feb 12.

Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106 (USA).

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http://dx.doi.org/10.1002/cbic.201200649DOI Listing
March 2013

Inhibition of AKT with the orally active allosteric AKT inhibitor, MK-2206, sensitizes endometrial cancer cells to progestin.

PLoS One 2012 24;7(7):e41593. Epub 2012 Jul 24.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041593PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404036PMC
February 2013

Insights into the roles of desolvation and π-electron interactions during DNA polymerization.

Chembiochem 2013 Mar 12;14(4):489-98. Epub 2013 Feb 12.

Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106 (USA).

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http://dx.doi.org/10.1002/cbic.201200649DOI Listing
March 2013

Spectroscopic analysis of polymerization and exonuclease proofreading by a high-fidelity DNA polymerase during translesion DNA synthesis.

Biochim Biophys Acta 2013 Jan 28;1834(1):34-45. Epub 2012 Aug 28.

Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S157096391200192
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http://dx.doi.org/10.1016/j.bbapap.2012.08.019DOI Listing
January 2013

The relationships of social support, uncertainty, self-efficacy, and commitment to prenatal psychosocial adaptation.

J Adv Nurs 2012 Dec 23;68(12):2633-45. Epub 2012 Feb 23.

School of Nursing The University of Hong Kong.

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http://dx.doi.org/10.1111/j.1365-2648.2012.05962.xDOI Listing
December 2012

A non-natural nucleoside with combined therapeutic and diagnostic activities against leukemia.

ACS Chem Biol 2012 Jun 13;7(6):988-98. Epub 2012 Mar 13.

Departments of Chemistry , Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1021/cb300038fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376215PMC
June 2012

Watching Their Steps: Integrating Vision Intervention Into Daily Practice to Limit Fall Risk at Skilled Nursing Facilities.

OT Pract 2012 Jun;17(11):7-16

the Division of Occupational Science and Occupational Therapy at the University of Southern California.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285353PMC
June 2012

Identification of a region in the N-terminus of Escherichia coli Lon that affects ATPase, substrate translocation and proteolytic activity.

J Mol Biol 2012 May 1;418(3-4):208-25. Epub 2012 Mar 1.

Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.jmb.2012.02.039DOI Listing
May 2012

Photogenerated lectin sensors produced by thiol-ene/yne photo-click chemistry in aqueous solution.

Biosens Bioelectron 2012 Apr 28;34(1):51-6. Epub 2012 Jan 28.

KTH Royal Institute of Technology, Department of Chemistry, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bios.2012.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405975PMC
April 2012

Gold-containing indoles as anticancer agents that potentiate the cytotoxic effects of ionizing radiation.

J Med Chem 2012 Mar 15;55(5):2437-51. Epub 2012 Feb 15.

Department of Pharmacology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/jm2005942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326641PMC
March 2012

A general method to determine ionization constants of responsive polymer thin films.

J Colloid Interface Sci 2012 Jan 3;365(1):178-83. Epub 2011 Sep 3.

Department of Chemistry, Portland State University, PO Box 751, Portland, OR 97207-0751, USA.

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http://dx.doi.org/10.1016/j.jcis.2011.08.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034268PMC
January 2012

Multitasking in the mitochondrion by the ATP-dependent Lon protease.

Biochim Biophys Acta 2012 Jan 18;1823(1):56-66. Epub 2011 Nov 18.

Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 South Orange Avenue, MSB E-633, Newark, New Jersey 07103 USA.

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http://dx.doi.org/10.1016/j.bbamcr.2011.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263341PMC
January 2012

An implantable biofuel cell for a live insect.

J Am Chem Soc 2012 Jan 13;134(3):1458-60. Epub 2012 Jan 13.

Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://pubs.acs.org/doi/10.1021/ja210794c
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http://dx.doi.org/10.1021/ja210794cDOI Listing
January 2012

Bifunctional trehalose anode incorporating two covalently linked enzymes acting in series.

Anal Chem 2011 Oct 1;83(19):7408-11. Epub 2011 Sep 1.

Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106-7078, USA.

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http://dx.doi.org/10.1021/ac2014417DOI Listing
October 2011

Impact of baby-friendly hospital practices on breastfeeding in Hong Kong.

Birth 2011 Sep 20;38(3):238-45. Epub 2011 May 20.

School of Nursing, University of Hong Kong.

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http://dx.doi.org/10.1111/j.1523-536X.2011.00483.xDOI Listing
September 2011

Active-site-directed chemical tools for profiling mitochondrial Lon protease.

ACS Chem Biol 2011 Aug 6;6(8):781-8. Epub 2011 May 6.

Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07101-1709, United States.

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http://dx.doi.org/10.1021/cb100408wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158820PMC
August 2011

Bilateral orbital bone infarction in sickle-cell disease.

Ophthalmic Plast Reconstr Surg 2011 Mar-Apr;27(2):e26-7

Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1097/IOP.0b013e3181c70b65DOI Listing
May 2011

Association of FMR1 genotypes with in vitro fertilization (IVF) outcomes based on ethnicity/race.

PLoS One 2011 Apr 15;6(4):e18781. Epub 2011 Apr 15.

Center for Human Reproduction and Foundation for Reproductive Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0018781PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078144PMC
April 2011

Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis.

Nucleic Acids Res 2011 Mar 15;39(4):1623-37. Epub 2010 Oct 15.

Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045600PMC
March 2011

FMR1 genotype with autoimmunity-associated polycystic ovary-like phenotype and decreased pregnancy chance.

PLoS One 2010 Dec 16;5(12):e15303. Epub 2010 Dec 16.

Center for Human Reproduction (CHR) and Foundation for Reproductive Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015303PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002956PMC
December 2010

N-Terminal peptidic boronic acids selectively inhibit human ClpXP.

Org Biomol Chem 2010 Aug 4;8(15):3451-6. Epub 2010 Jun 4.

Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, USA.

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http://dx.doi.org/10.1039/c004247aDOI Listing
August 2010

Increasing Asian American women's research participation: the Asian grocery store-based cancer education program.

Contemp Clin Trials 2010 Jul 15;31(4):283-8. Epub 2010 Mar 15.

Rebecca and John Moores UCSD Cancer Center, 3855 Health Sciences Drive #0850, La Jolla, CA 92093-0850, USA.

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http://dx.doi.org/10.1016/j.cct.2010.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891128PMC
July 2010

Non-natural nucleotides as probes for the mechanism and fidelity of DNA polymerases.

Biochim Biophys Acta 2010 May 3;1804(5):1064-80. Epub 2009 Sep 3.

Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.bbapap.2009.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149816PMC
May 2010

Breastfeeding and weaning practices among Hong Kong mothers: a prospective study.

BMC Pregnancy Childbirth 2010 May 29;10:27. Epub 2010 May 29.

School of Nursing, Li Ka Shing Faculty of Medicine, 21 Sassoon Road, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1186/1471-2393-10-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887376PMC
May 2010

Replication of a universal nucleobase provides unique insight into the role of entropy during DNA polymerization and pyrophosphorolysis.

Biochemistry 2010 Apr;49(14):3009-23

Department of Pharmacology, Case Western Reserve University,10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi901523y
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http://dx.doi.org/10.1021/bi901523yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172712PMC
April 2010

Utilization of positional isotope exchange experiments to evaluate reversibility of ATP hydrolysis catalyzed by Escherichia coli Lon protease.

Biochem Cell Biol 2010 Feb;88(1):119-28

WIL Research Laboratories, LLC, Ashland, OH 44805, USA.

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http://dx.doi.org/10.1139/o09-117DOI Listing
February 2010

Oxidant stress in HIV-infected women from the Women's Interagency HIV Study.

Antivir Ther 2009 ;14(6):763-9

Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.3851/IMP1290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760028PMC
December 2009

Utilization of synthetic peptides to evaluate the importance of substrate interaction at the proteolytic site of Escherichia coli Lon protease.

Biochim Biophys Acta 2009 Sep 11;1794(9):1355-63. Epub 2009 Mar 11.

Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106-7078, USA.

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http://dx.doi.org/10.1016/j.bbapap.2009.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738752PMC
September 2009

Plasma homocysteine is not associated with HIV serostatus or antiretroviral therapy in women.

J Acquir Immune Defic Syndr 2009 Jun;51(2):175-8

Department of Medicine, St. Luke's-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY, USA.

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http://dx.doi.org/10.1097/QAI.0b013e3181a42bdfDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755615PMC
June 2009

Validated robotic laparoscopic surgical training in a virtual-reality environment.

Surg Endosc 2009 Jan 10;23(1):66-73. Epub 2008 Apr 10.

HPER Biomechanics Lab, University of Nebraska at Omaha, Omaha, NE 68182-0216, USA.

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http://dx.doi.org/10.1007/s00464-008-9894-zDOI Listing
January 2009

Mechanism and dynamics of translesion DNA synthesis catalyzed by the Escherichia coli Klenow fragment.

Biochemistry 2008 Aug 25;47(33):8527-37. Epub 2008 Jul 25.

Departments of Pharmacology and Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi800324r
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692461PMC
August 2008

Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates.

Biochim Biophys Acta 2008 May 5;1784(5):727-35. Epub 2008 Mar 5.

Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106-7078, USA.

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http://dx.doi.org/10.1016/j.bbapap.2008.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443057PMC
May 2008

Resolving individual steps in the operation of ATP-dependent proteolytic molecular machines: from conformational changes to substrate translocation and processivity.

Biochemistry 2008 Mar 1;47(12):3595-605. Epub 2008 Mar 1.

Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi800025g
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March 2008

Towards the control of intracellular protein turnover: mitochondrial Lon protease inhibitors versus proteasome inhibitors.

Biochimie 2008 Feb 25;90(2):260-9. Epub 2007 Oct 25.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106 / IFR 117, Université Paris 7-Denis Diderot, 2 place Jussieu, Tour 33-23, 1(er) étage, CC 7128, 75251 Paris cedex 05, France.

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http://dx.doi.org/10.1016/j.biochi.2007.10.010DOI Listing
February 2008

Reversible hypertensive brainstem oedema.

Hong Kong Med J 2008 Feb;14(1):74-5

Department of Medicine and Geriatrics, Princess Margaret Hospital, Laichikok, Kowloon, Hong Kong.

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February 2008

Enhancing the "A-rule" of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates.

Biochemistry 2007 Dec 6;46(48):13752-61. Epub 2007 Nov 6.

Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi701328h
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December 2007

Optimization of non-natural nucleotides for selective incorporation opposite damaged DNA.

Org Biomol Chem 2007 Nov 12;5(22):3623-30. Epub 2007 Oct 12.

Department of Pharmacology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1039/b712480eDOI Listing
November 2007

Detection and characterization of two ATP-dependent conformational changes in proteolytically inactive Escherichia coli Lon mutants by stopped flow kinetic techniques.

Biochemistry 2007 Nov 2;46(47):13593-605. Epub 2007 Nov 2.

Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi701649bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2537469PMC
November 2007

Peptidyl boronates inhibit Salmonella enterica serovar Typhimurium Lon protease by a competitive ATP-dependent mechanism.

Biochemistry 2007 Jun 12;46(22):6647-57. Epub 2007 May 12.

Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi7002789DOI Listing
June 2007

Is a thymine dimer replicated via a transient abasic site intermediate? A comparative study using non-natural nucleotides.

Biochemistry 2007 Apr 23;46(15):4486-98. Epub 2007 Mar 23.

Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi602438tDOI Listing
April 2007

Fluorescent analysis of translesion DNA synthesis by using a novel, non-natural nucleotide analogue.

Chembiochem 2006 Dec;7(12):1990-7

Case Western Reserve University, 2109 Adelbert Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1002/cbic.200600128DOI Listing
December 2006

Rational attempts to optimize non-natural nucleotides for selective incorporation opposite an abasic site.

Biochemistry 2006 Nov;45(44):13293-303

Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi060418v
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November 2006

Recent developments in the mechanistic enzymology of the ATP-dependent Lon protease from Escherichia coli: highlights from kinetic studies.

Mol Biosyst 2006 Oct 24;2(10):477-83. Epub 2006 Aug 24.

Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1039/b609936jDOI Listing
October 2006

Transient kinetic experiments demonstrate the existence of a unique catalytic enzyme form in the peptide-stimulated ATPase mechanism of Escherichia coli Lon protease.

Biochemistry 2006 Sep;45(38):11432-43

Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi060809+DOI Listing
September 2006

Identification of the proteasome inhibitor MG262 as a potent ATP-dependent inhibitor of the Salmonella enterica serovar Typhimurium Lon protease.

Biochemistry 2006 Jul;45(27):8264-74

Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi060542eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515377PMC
July 2006

Hydrophobicity, shape, and pi-electron contributions during translesion DNA synthesis.

J Am Chem Soc 2006 Jan;128(1):143-9

Departments of Pharmacology and Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://pubs.acs.org/doi/abs/10.1021/ja0546830
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January 2006

The use of nonnatural nucleotides to probe the contributions of shape complementarity and pi-electron surface area during DNA polymerization.

Biochemistry 2005 Oct;44(39):13101-10

Department of Pharmacology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi050585fDOI Listing
October 2005

A potential chemotherapeutic strategy for the selective inhibition of promutagenic DNA synthesis by nonnatural nucleotides.

Biochemistry 2005 Oct;44(39):13111-21

Department of Pharmacology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi050584n
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October 2005

Monitoring the timing of ATP hydrolysis with activation of peptide cleavage in Escherichia coli Lon by transient kinetics.

Biochemistry 2005 Feb;44(5):1671-82

Department of Chemistry and Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi048618zDOI Listing
February 2005

Prevalence of infectious diseases in feral cats in Northern Florida.

J Feline Med Surg 2004 Oct;6(5):287-96

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 S.W. 16th Avenue, Box 100126, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1016/j.jfms.2003.11.005DOI Listing
October 2004

Cytologic diagnosis of invasive lobular carcinoma: factors associated with negative and equivocal diagnoses.

Diagn Cytopathol 2004 Aug;31(2):87-93

Division of Cytopathology, Department of Pathology, New York University Medical Center, New York, New York 10016, USA.

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http://dx.doi.org/10.1002/dc.20084DOI Listing
August 2004

Correlation of an adenine-specific conformational change with the ATP-dependent peptidase activity of Escherichia coli Lon.

Biochemistry 2004 Jun;43(23):7432-42

Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi036165cDOI Listing
June 2004

Evaluating the contributions of desolvation and base-stacking during translesion DNA synthesis.

Org Biomol Chem 2004 Jun 19;2(12):1703-11. Epub 2004 May 19.

Department of Pharmacology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1039/b401732cDOI Listing
June 2004

DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate.

J Biol Chem 2004 Apr 22;279(14):13902-10. Epub 2004 Jan 22.

Department of Biochemistry and Molecular Biology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103, USA.

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http://dx.doi.org/10.1074/jbc.M309642200DOI Listing
April 2004

Aspiration biopsy of mammary lesions with abundant extracellular mucinous material. Review of 43 cases with surgical follow-up.

Am J Clin Pathol 2003 Aug;120(2):194-202

Department of Pathology, Division of Cytopathology, New York University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1309/2MKQ-RJ3D-LPMT-4LJADOI Listing
August 2003