Publications by authors named "Irene Bosch"

48Publications

Importance of clinical and laboratory characteristics in the diagnosis of dengue and chikungunya co-infection: Probable case report

Biomedica 2020 09 1;40(3):472-478. Epub 2020 Sep 1.

Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, United States of América.

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September 2020

Point-of-Care Devices to Detect Zika and Other Emerging Viruses.

Annu Rev Biomed Eng 2020 06;22:371-386

Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA; email:

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June 2020

Clinical, laboratory and immune aspects of Zika virus-associated encephalitis in children.

Int J Infect Dis 2020 Jan 31;90:104-110. Epub 2019 Oct 31.

Programa de Medicina, Facultad de Salud, Universidad Surcolombiana, Neiva, Huila, Colombia; Especialización Médica en Pediatría, Postgrados Clínicos, Facultad de Salud, Universidad Surcolombiana, Neiva, Huila, Colombia. Electronic address:

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January 2020

Molecular characterization of dengue virus reveals regional diversification of serotype 2 in Colombia.

Virol J 2019 05 8;16(1):62. Epub 2019 May 8.

Grupo de Virología, Dirección de Redes en Salud Pública, Instituto Nacional de Salud, Avenida Calle 26 N° 51-20 CAN, Bogotá DC, Colombia.

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May 2019

Challenges of the Nano-Bio Interface in Lateral Flow and Dipstick Immunoassays.

Trends Biotechnol 2017 12 28;35(12):1169-1180. Epub 2017 Sep 28.

Department of Mechanical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA; Department of Engineering, University of Massachusetts Boston, Boston, MA, USA. Electronic address:

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December 2017

Design of SERS nanotags for multiplexed lateral flow immunoassays.

Mol Syst Des Eng 2017 Oct 27;2(4):401-409. Epub 2017 Sep 27.

Department of Engineering, University of Massachusetts Boston, Boston, MA.

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October 2017

Surface-Enhanced Raman Spectroscopy-Based Sandwich Immunoassays for Multiplexed Detection of Zika and Dengue Viral Biomarkers.

ACS Infect Dis 2017 10 6;3(10):767-776. Epub 2017 Sep 6.

Department of Engineering, University of Massachusetts Boston , 100 Morrissey Blvd., Boston, Massachusetts 02125, United States.

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October 2017

[Serum activity of CK and CK-MB in patients with dengue virus infection].

Rev Salud Publica (Bogota) 2017 Jul-Aug;19(4):460-467

BR: MD. M. Sc. Instituto Colombiano de Medicina Tropical- Universidad CES, Sabaneta, Colombia.

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January 2019

Effect of the Protein Corona on Antibody-Antigen Binding in Nanoparticle Sandwich Immunoassays.

Bioconjug Chem 2017 01 8;28(1):230-238. Epub 2016 Dec 8.

Department of Engineering, University of Massachusetts Boston , Boston, Massachusetts 02125, United States.

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January 2017

Induction of Expansion and Folding in Human Cerebral Organoids.

Cell Stem Cell 2017 03 29;20(3):385-396.e3. Epub 2016 Dec 29.

The Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, 31 Ames Street, Cambridge, MA 02139, USA. Electronic address:

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March 2017

A comparison of nanoparticle-antibody conjugation strategies in sandwich immunoassays.

J Immunoassay Immunochem 2017 16;38(4):355-377. Epub 2016 Dec 16.

c Institute for Medical Engineering and Science, Massachusetts Institute of Technology , Cambridge , Massachusetts.

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January 2018

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components.

Cell 2016 May 6;165(5):1255-1266. Epub 2016 May 6.

Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA; Harvard-MIT Program in Health Sciences and Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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May 2016

Dengue virus type 3 adaptive changes during epidemics in São Jose de Rio Preto, Brazil, 2006-2007.

PLoS One 2013 7;8(5):e63496. Epub 2013 May 7.

Laboratório de Evolução Molecular e Bioinformática (LEMB), Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.

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December 2013

Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor.

Circulation 2013 Jan 25;127(3):365-76. Epub 2012 Dec 25.

Harvard-MIT Division of Science and Technology, Bldg E25-449, Massachusetts Institute of Technology, 77 Mass Ave, Cambridge, MA 02139, USA.

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January 2013

Population dynamics of DENV-1 genotype V in Brazil is characterized by co-circulation and strain/lineage replacement.

Arch Virol 2012 Nov 10;157(11):2061-73. Epub 2012 Jul 10.

Laboratório de Virologia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.

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November 2012

CD8+ T cells use TRAIL to restrict West Nile virus pathogenesis by controlling infection in neurons.

J Virol 2012 Sep 27;86(17):8937-48. Epub 2012 Jun 27.

Departments of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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September 2012

Gene expression profiling of dengue infected human primary cells identifies secreted mediators in vivo.

J Med Virol 2009 Aug;81(8):1403-11

Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, 01655, USA.

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August 2009

Increased activity of indoleamine 2,3-dioxygenase in serum from acutely infected dengue patients linked to gamma interferon antiviral function.

J Gen Virol 2009 Apr 4;90(Pt 4):810-817. Epub 2009 Mar 4.

Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.

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April 2009

Elevated levels of soluble ST2 protein in dengue virus infected patients.

Cytokine 2008 Feb 28;41(2):114-20. Epub 2008 Jan 28.

Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.

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February 2008

TRAIL is a novel antiviral protein against dengue virus.

J Virol 2008 Jan 3;82(1):555-64. Epub 2007 Oct 3.

Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, S6-712, 55 Lake Ave. North, Worcester, MA 01655, USA.

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January 2008

Discovering innate immunity genes using differential display: a story of RNA helicases.

J Cell Physiol 2006 Dec;209(3):636-44

Center for Infectious Disease and Vaccine Research, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.

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December 2006

Dengue virus induces novel changes in gene expression of human umbilical vein endothelial cells.

J Virol 2003 Nov;77(21):11822-32

Center for Infectious Disease and Vaccine Research and Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

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November 2003

Increased production of interleukin-8 in primary human monocytes and in human epithelial and endothelial cell lines after dengue virus challenge.

J Virol 2002 Jun;76(11):5588-97

Center for Infectious Disease and Vaccine Research and Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

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June 2002