Dr. Ioannis P Androulakis, BS, MS, PhD - Rutgers University - Professor

Dr. Ioannis P Androulakis

BS, MS, PhD

Rutgers University

Professor

Pisctaway, NJ | United States

Dr. Ioannis P Androulakis, BS, MS, PhD - Rutgers University - Professor

Dr. Ioannis P Androulakis

BS, MS, PhD

Introduction

Dr. Androulakis is a Professor in the Department of Biomedical Engineering, the Department of Chemical & Biochemical Engineering and hold an Adjuct faculty position in the Department of Surgery at the Rutgers-RWJ Medical School. His research focuses on systems biology and pharmacology of inflammation with special emphasis on the interactions between the circadian and immune systems. He is Fellow of the American Institute for Medical and Biological Engineering. Dr. Androulakis holds a BS degree from NTUA, Athens, Greece; MS/PhD from Purdue University, all in Chemical Engineering. He was a Research Associate at Princeton University and prior to joining Rutgers was with ExxonMobil's Corporate Strategic Research Laboratories in NJ. For more information please see www.ipandro.com

Primary Affiliation: Rutgers University - Pisctaway, NJ , United States

Research Interests:

Publications

92Publications

1050Reads

6Profile Views

784PubMed Central Citations

Mathematical modeling informs the impact of changes in circadian rhythms and meal patterns on insulin secretion.

Am J Physiol Regul Integr Comp Physiol 2019 07 1;317(1):R98-R107. Epub 2019 May 1.

Chemical & Biochemical Engineering Department, Rutgers University , Piscataway, New Jersey.

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http://dx.doi.org/10.1152/ajpregu.00230.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692763PMC
July 2019
3.106 Impact Factor

The physiological significance of the circadian dynamics of the HPA axis: Interplay between circadian rhythms, allostasis and stress resilience.

Horm Behav 2019 04 15;110:77-89. Epub 2019 Mar 15.

Chemical & Biochemical Engineering Department, Rutgers University, Piscataway, NJ, United States of America; Biomedical Engineering Department, Rutgers University, Piscataway, NJ, United States of America; Department of Surgery, Rutgers - Robert Wood Johnson Medical School, New Brunswick, NJ, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.yhbeh.2019.02.018DOI Listing
April 2019
3 Reads
4.632 Impact Factor

Pathway-Based Analysis of the Liver Response to Intravenous Methylprednisolone Administration in Rats: Acute Versus Chronic Dosing.

Gene Regul Syst Bio 2019 15;13:1177625019840282. Epub 2019 Apr 15.

Department of Biomedical Engineering, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.

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http://dx.doi.org/10.1177/1177625019840282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466473PMC
April 2019
4 Reads

Chronopharmacology of glucocorticoids.

Adv Drug Deliv Rev 2019 Nov - Dec;151-152:245-261. Epub 2019 Feb 21.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, 98 Brett Road, Piscataway, NJ 08854, United States; Department of Biomedical Engineering, Rutgers The State University of New Jersey, 599 Taylor Road, Piscataway, NJ 08854, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2019.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703983PMC
February 2019
4 Reads
15.038 Impact Factor

Exploration of sexual dimorphism and inter-individual variability in multivariate parameter spaces for a pharmacokinetic compartment model.

Math Biosci 2019 02 15;308:70-80. Epub 2018 Dec 15.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, 98 Brett Road, Piscataway, NJ 08854, United States; Department of Biomedical Engineering, Rutgers, The State University of New Jersey, 599 Taylor Road, Piscataway, NJ 08854, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mbs.2018.12.011DOI Listing
February 2019
5 Reads
1.303 Impact Factor

Modeling the influence of chronopharmacological administration of synthetic glucocorticoids on the hypothalamic-pituitary-adrenal axis.

Chronobiol Int 2018 11 30;35(12):1619-1636. Epub 2018 Jul 30.

a Department of Chemical and Biochemical Engineering , Rutgers, The State University of New Jersey , Piscataway , New Jersey , USA.

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http://dx.doi.org/10.1080/07420528.2018.1498098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292202PMC
November 2018
50 Reads
3.343 Impact Factor

Mathematical analysis of circadian disruption and metabolic re-entrainment of hepatic gluconeogenesis: the intertwining entraining roles of light and feeding.

Am J Physiol Endocrinol Metab 2018 06 9;314(6):E531-E542. Epub 2018 Jan 9.

Chemical & Biochemical Engineering Department, Rutgers University , Piscataway, New Jersey.

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http://dx.doi.org/10.1152/ajpendo.00271.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032066PMC
June 2018
7 Reads
1 Citation
3.790 Impact Factor

Pharmacokinetics and Pharmacodynamics of Curcumin in regulating anti-inflammatory and epigenetic gene expression.

Biopharm Drug Dispos 2018 Jun;39(6):289-297

Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.

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http://dx.doi.org/10.1002/bdd.2136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078813PMC
June 2018
65 Reads
2.180 Impact Factor

Modeling the Influence of Seasonal Differences in the HPA Axis on Synchronization of the Circadian Clock and Cell Cycle.

Endocrinology 2018 04;159(4):1808-1826

Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, New Jersey.

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http://dx.doi.org/10.1210/en.2017-03226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044315PMC
April 2018
1 Read
4.503 Impact Factor

A framework for 2-stage global sensitivity analysis of GastroPlus™ compartmental models.

J Pharmacokinet Pharmacodyn 2018 04 8;45(2):309-327. Epub 2018 Feb 8.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, 98 Brett Road, Piscataway, NJ, 08854, USA.

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http://dx.doi.org/10.1007/s10928-018-9573-1DOI Listing
April 2018
9 Reads
1.460 Impact Factor

Physiologically-based pharmacokinetic models: approaches for enabling personalized medicine.

J Pharmacokinet Pharmacodyn 2016 10 19;43(5):481-504. Epub 2016 Sep 19.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, 98 Brett Road, Piscataway, NJ, 08854, USA.

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http://dx.doi.org/10.1007/s10928-016-9492-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204363PMC
October 2016
88 Reads
6 Citations
1.460 Impact Factor

The role of the hypothalamic-pituitary-adrenal axis in modulating seasonal changes in immunity.

Physiol Genomics 2016 10 24;48(10):719-738. Epub 2016 Jun 24.

Biomedical Engineering Department, Rutgers University, Piscataway, New Jersey; Chemical and Biochemical Engineering Department, Rutgers University, Piscataway, New Jersey; and Department of Surgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey

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http://dx.doi.org/10.1152/physiolgenomics.00006.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243227PMC
October 2016
1 Read
7 Citations
2.374 Impact Factor

Quantitative Systems Pharmacology: A Framework for Context.

Curr Pharmacol Rep 2016 Jun 8;2(3):152-160. Epub 2016 Apr 8.

Biomedical Engineering Department, Chemical & Biochemical Engineering Department, Rutgers University, Piscataway, NJ 08854.

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http://dx.doi.org/10.1007/s40495-016-0058-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996481PMC
June 2016
3 Reads
3 Citations

Burn trauma disrupts circadian rhythms in rat liver.

Int J Burns Trauma 2016 1;6(2):12-25. Epub 2016 Jun 1.

Chemical and Biochemical Engineering Department, Rutgers, The State University of New JerseyPiscataway, NJ 08854, USA; Biomedical Engineering Department, Rutgers, The State University of New JerseyPiscataway, NJ 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913229PMC
June 2016
4 Reads
2 Citations

Systems engineering meets quantitative systems pharmacology: from low-level targets to engaging the host defenses.

Wiley Interdiscip Rev Syst Biol Med 2015 May-Jun;7(3):101-12. Epub 2015 Mar 16.

Biomedical Engineering Department, Rutgers University, Piscataway, NJ, USA.

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http://dx.doi.org/10.1002/wsbm.1294DOI Listing
March 2016
1 Read
5 Citations

Pharmacokinetics and pharmacodynamics of 3,3'-diindolylmethane (DIM) in regulating gene expression of phase II drug metabolizing enzymes.

J Pharmacokinet Pharmacodyn 2015 Aug 3;42(4):401-8. Epub 2015 Jul 3.

Department of Pharmacology, Tzu Chi University, Hualien City, Taiwan.

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http://dx.doi.org/10.1007/s10928-015-9421-5DOI Listing
August 2015
28 Reads
3 Citations
1.460 Impact Factor

Dynamics of hepatic gene expression and serum cytokine profiles in single and double-hit burn and sepsis animal models.

Data Brief 2015 Jun 11;3:229-33. Epub 2015 Mar 11.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA ; Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.dib.2015.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510136PMC
June 2015
6 Reads
1 Citation

Circadian characteristics of permissive and suppressive effects of cortisol and their role in homeostasis and the acute inflammatory response.

Math Biosci 2015 Feb 31;260:54-64. Epub 2014 Oct 31.

Chemical & Biochemical Engineering Department, Rutgers University, Piscataway, NJ, United States; Department of Surgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, United States; Biomedical Engineering Department, Rutgers University, Piscataway, NJ, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mbs.2014.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306649PMC
February 2015
2 Reads
12 Citations
1.303 Impact Factor

Tandem analysis of transcriptome and proteome changes after a single dose of corticosteroid: a systems approach to liver function in pharmacogenomics.

OMICS 2015 Feb 22;19(2):80-91. Epub 2015 Jan 22.

1 Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey , Piscataway, New Jersey.

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http://dx.doi.org/10.1089/omi.2014.0130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322790PMC
February 2015
61 Reads
5 Citations
2.362 Impact Factor

A Chemical Engineer's Perspective on Health and Disease.

Comput Chem Eng 2014 Dec;71:665-671

Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, NJ 08854 ; Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854 ; Department of Surgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08901.

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http://dx.doi.org/10.1016/j.compchemeng.2014.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260424PMC
December 2014
3 Reads
1 Citation
2.784 Impact Factor

Integrated transcriptional and metabolic profiling in human endotoxemia.

Shock 2014 Dec;42(6):499-508

*Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway; †Department of Surgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick; and ‡Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, New Jersey.

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http://dx.doi.org/10.1097/SHK.0000000000000248DOI Listing
December 2014
1 Read
5 Citations
3.045 Impact Factor

Mathematical modeling of light-mediated HPA axis activity and downstream implications on the entrainment of peripheral clock genes.

Physiol Genomics 2014 Oct 29;46(20):766-78. Epub 2014 Jul 29.

Chemical & Biochemical Engineering Department, Rutgers University, Piscataway, New Jersey; Department of Surgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey; and Biomedical Engineering Department, Rutgers University, Piscataway, New Jersey

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http://dx.doi.org/10.1152/physiolgenomics.00026.2014DOI Listing
October 2014
4 Reads
12 Citations
2.374 Impact Factor

Effects of coupled dose and rhythm manipulation of plasma cortisol levels on leukocyte transcriptional response to endotoxin challenge in humans.

Innate Immun 2014 Oct 11;20(7):774-84. Epub 2013 Nov 11.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, USA Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, USA Department of Surgery, Rutgers, Robert Wood Johnson Medical School, Clinical Academic Building, New Brunswick, NJ, USA

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http://ini.sagepub.com/content/20/7/774.full.pdf
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http://ini.sagepub.com/cgi/doi/10.1177/1753425913508458
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http://dx.doi.org/10.1177/1753425913508458DOI Listing
October 2014
5 Reads
4 Citations
3.271 Impact Factor

On heart rate variability and autonomic activity in homeostasis and in systemic inflammation.

Math Biosci 2014 Jun 26;252:36-44. Epub 2014 Mar 26.

Department of Biomedical Engineering, Rutgers University, 599 Taylor Road, Piscataway, NJ 08854, USA; Department of Surgery, Robert Wood Johnson Medical School, Clinical Academic Building, 125 Patterson Street, New Brunswick, NJ 08901, USA; Department of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mbs.2014.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159048PMC
June 2014
3 Reads
3 Citations
1.303 Impact Factor

Metabolomic fingerprinting: challenges and opportunities.

Crit Rev Biomed Eng 2013 ;41(3):205-21

Department of Surgery, Robert Wood Johnson Medical School, Department of Biomedical Engineering, Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096240PMC
http://dx.doi.org/10.1615/critrevbiomedeng.2013007736DOI Listing
April 2014
2 Reads
9 Citations

Bioinformatics analysis of transcriptional regulation of circadian genes in rat liver.

BMC Bioinformatics 2014 Mar 25;15:83. Epub 2014 Mar 25.

Chemical and Biochemical Engineering Department, Rutgers the State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1186/1471-2105-15-83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987685PMC
March 2014
39 Reads
6 Citations
2.580 Impact Factor

Time-restricted feeding and the realignment of biological rhythms: translational opportunities and challenges.

J Transl Med 2014 Mar 28;12:79. Epub 2014 Mar 28.

Biomedical Engineering Department, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1186/1479-5876-12-79DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973614PMC
March 2014
105 Reads
7 Citations
3.930 Impact Factor

Tissue-specific gene expression and regulation in liver and muscle following chronic corticosteroid administration.

Gene Regul Syst Bio 2014 10;8:75-87. Epub 2014 Mar 10.

Biomedical Engineering Department, Rutgers University, Piscataway, NJ, USA. ; Chemical and Biochemical Engineering Department, Rutgers University, Piscataway, NJ, USA.

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http://dx.doi.org/10.4137/GRSB.S13134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956809PMC
March 2014
34 Reads
3 Citations

Topology and dynamics of signaling networks: in search of transcriptional control of the inflammatory response.

Annu Rev Biomed Eng 2013 ;15:1-28

Chemical & Biochemical Engineering Department, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1146/annurev-bioeng-071812-152425DOI Listing
February 2014
6 Reads
6 Citations
14.211 Impact Factor

Branched-chain amino acid supplementation: impact on signaling and relevance to critical illness.

Wiley Interdiscip Rev Syst Biol Med 2013 Jul-Aug;5(4):449-460. Epub 2013 Mar 29.

Department of Biomedical Engineering, Rutgers, the State University of New Jersey, Piscataway, New Jersey.

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http://dx.doi.org/10.1002/wsbm.1219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482218PMC
January 2014
2 Reads
6 Citations

Predicting critical transitions in a model of systemic inflammation.

J Theor Biol 2013 Dec 21;338:9-15. Epub 2013 Aug 21.

Department of Biomedical Engineering, Rutgers University, 599 Taylor Road, Piscataway, NJ 08854, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jtbi.2013.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870185PMC
December 2013
3 Citations
2.120 Impact Factor

Temporal metabolic profiling of plasma during endotoxemia in humans.

Shock 2013 Dec;40(6):519-26

Departments of *Chemical and Biochemical Engineering and †Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway; and ‡Department of Surgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey.

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http://dx.doi.org/10.1097/SHK.0000000000000063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970546PMC
December 2013
5 Reads
10 Citations
3.045 Impact Factor

Use of genomic data in risk assessment case study: II. Evaluation of the dibutyl phthalate toxicogenomic data set.

Toxicol Appl Pharmacol 2013 Sep 30;271(3):349-62. Epub 2011 Jun 30.

National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2011.06.014DOI Listing
September 2013
39 Reads
6 Citations
3.705 Impact Factor

Enzyme sequence similarity improves the reaction alignment method for cross-species pathway comparison.

Toxicol Appl Pharmacol 2013 Sep 17;271(3):363-71. Epub 2010 Sep 17.

Chemical and Biochemical Engineering Department, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.taap.2010.09.009DOI Listing
September 2013
3 Reads
2 Citations
3.705 Impact Factor

A Systems Engineering Perspective on Homeostasis and Disease.

Front Bioeng Biotechnol 2013 9;1. Epub 2013 Sep 9.

Department of Biomedical Engineering, Rutgers University , Piscataway, NJ , USA ; Department of Chemical and Biochemical Engineering, Rutgers University , Piscataway, NJ , USA ; Department of Surgery, Rutgers Robert Wood Johnson Medical School , New Brunswick, NJ , USA.

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http://dx.doi.org/10.3389/fbioe.2013.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090890PMC
September 2013
5 Reads
5 Citations

Pathway modeling of microarray data: a case study of pathway activity changes in the testis following in utero exposure to dibutyl phthalate (DBP).

Toxicol Appl Pharmacol 2013 Sep 17;271(3):386-94. Epub 2010 Sep 17.

Chemical and Biochemical Engineering Department, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.taap.2010.09.008DOI Listing
September 2013
43 Reads
4 Citations
3.705 Impact Factor

Effect of fasting on the metabolic response of liver to experimental burn injury.

PLoS One 2013 5;8(2):e54825. Epub 2013 Feb 5.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, New Jersey, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054825PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564862PMC
August 2013
3 Reads
1 Citation
3.234 Impact Factor

Translational applications of evaluating physiologic variability in human endotoxemia.

J Clin Monit Comput 2013 Aug 1;27(4):405-15. Epub 2012 Dec 1.

Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1007/s10877-012-9418-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664105PMC
August 2013
1 Read
8 Citations
1.450 Impact Factor

An agent-based model of cellular dynamics and circadian variability in human endotoxemia.

PLoS One 2013 30;8(1):e55550. Epub 2013 Jan 30.

BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055550PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559552PMC
July 2013
2 Reads
9 Citations
3.234 Impact Factor

Impact of burn priming on immune and metabolic functions of whole Liver in a rat cecal ligation and puncture model.

Int J Burns Trauma 2013 24;3(1):55-65. Epub 2013 Jan 24.

Chemical and Biochemical Engineering Department, Rutgers, the State University of New Jersey Piscataway, NJ, 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560487PMC
April 2013
7 Reads
3 Citations

Special issue in memory of Dr. Stephen F. Lowry.

Crit Rev Biomed Eng 2012 ;40(4):259-361

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1615/critrevbiomedeng.v40.i4.10DOI Listing
January 2013
4 Reads

A semi-mechanistic integrated toxicokinetic-toxicodynamic (TK/TD) model for arsenic(III) in hepatocytes.

J Theor Biol 2013 Jan 12;317:244-56. Epub 2012 Oct 12.

Environmental and Occupational Health Sciences Institute (EOHSI) A Joint Institute of UMDNJ-Robert Wood Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.jtbi.2012.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026948PMC
January 2013
3 Reads
3 Citations
2.120 Impact Factor

Molecular mechanisms of chronic intermittent hypoxia and hypertension.

Crit Rev Biomed Eng 2012 ;40(4):265-78

UMDNJ- Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634614PMC
http://dx.doi.org/10.1615/critrevbiomedeng.v40.i4.30DOI Listing
January 2013
25 Reads
8 Citations

Modeling physiologic variability in human endotoxemia.

Crit Rev Biomed Eng 2012 ;40(4):313-22

Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604977PMC
http://dx.doi.org/10.1615/critrevbiomedeng.v40.i4.60DOI Listing
January 2013
6 Citations

Long-term gene expression profile dynamics following cecal ligation and puncture in the rat.

J Surg Res 2012 Nov 16;178(1):431-42. Epub 2012 Apr 16.

Department of Chemical and Biochemical Engineering, Rutgers, State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.jss.2012.03.052DOI Listing
November 2012
11 Reads
3 Citations
1.940 Impact Factor

Linking Inflammation, Cardiorespiratory Variability, and Neural Control in Acute Inflammation via Computational Modeling.

Front Physiol 2012 2;3:222. Epub 2012 Jul 2.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Case Western Reserve University Cleveland, OH, USA.

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http://dx.doi.org/10.3389/fphys.2012.00222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387781PMC
October 2012
34 Reads
13 Citations

Pharmacokinetics and pharmacodynamics of phase II drug metabolizing/antioxidant enzymes gene response by anticancer agent sulforaphane in rat lymphocytes.

Mol Pharm 2012 Oct 11;9(10):2819-27. Epub 2012 Sep 11.

Graduate Program in Pharmaceutical Sciences, Department of Pharmaceutics, Ernest Mario School of Pharmacy, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA.

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http://pubs.acs.org/doi/10.1021/mp300130k
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http://dx.doi.org/10.1021/mp300130kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580178PMC
October 2012
25 Reads
6 Citations
4.384 Impact Factor

Dynamics of short-term gene expression profiling in liver following thermal injury.

J Surg Res 2012 Aug 21;176(2):549-58. Epub 2011 Oct 21.

Chemical and Biochemical Engineering Department, Rutgers, the State University of New Jersey, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1016/j.jss.2011.09.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319855PMC
August 2012
3 Reads
7 Citations
1.940 Impact Factor

Entrainment of peripheral clock genes by cortisol.

Physiol Genomics 2012 Jun 17;44(11):607-21. Epub 2012 Apr 17.

Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, New Jersey, USA.

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June 2012
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Long-term dynamic profiling of inflammatory mediators in double-hit burn and sepsis animal models.

Cytokine 2012 May 7;58(2):307-15. Epub 2012 Mar 7.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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May 2012
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Advanced stoichiometric analysis of metabolic networks of mammalian systems.

Crit Rev Biomed Eng 2011 ;39(6):511-34

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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March 2012
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Stoichiometry based steady-state hepatic flux analysis: computational and experimental aspects.

Metabolites 2012 Mar 14;2(1):268-91. Epub 2012 Mar 14.

Department of Chemical and Biochemical Engineering, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.

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March 2012
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Transcriptional implications of ultradian glucocorticoid secretion in homeostasis and in the acute stress response.

Physiol Genomics 2012 Feb 29;44(2):121-9. Epub 2011 Nov 29.

Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA.

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February 2012
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Metabolic network analysis of perfused livers under fed and fasted states: incorporating thermodynamic and futile-cycle-associated regulatory constraints.

J Theor Biol 2012 Jan 21;293:101-10. Epub 2011 Oct 21.

Department of Chemical and Biochemical Engineering, Rutgers, State University of New Jersey, 98 Brett Road, Piscataway, NJ 08854, USA.

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January 2012
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Pulsatile glucocorticoid secretion: origins and downstream effects.

IEEE Trans Biomed Eng 2011 Dec 18;58(12):3504-7. Epub 2011 Jul 18.

Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA.

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December 2011
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Metabolic response of perfused livers to various oxygenation conditions.

Biotechnol Bioeng 2011 Dec 4;108(12):2947-57. Epub 2011 Aug 4.

Department of Chemical and Biochemical Engineering, Rutgers, State University of New Jersey, Piscataway, New Jersey 08854, USA.

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December 2011
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The dynamics of the early inflammatory response in double-hit burn and sepsis animal models.

Cytokine 2011 Nov 6;56(2):494-502. Epub 2011 Aug 6.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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November 2011
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Computational identification of transcriptional regulators in human endotoxemia.

PLoS One 2011 27;6(5):e18889. Epub 2011 May 27.

BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey, United States of America.

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September 2011
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Comparison of the cytokine and chemokine dynamics of the early inflammatory response in models of burn injury and infection.

Cytokine 2011 Sep 8;55(3):362-71. Epub 2011 Jun 8.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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September 2011
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A dual negative regulation model of Toll-like receptor 4 signaling for endotoxin preconditioning in human endotoxemia.

Math Biosci 2011 Aug 23;232(2):151-63. Epub 2011 May 23.

Chemical Engineering, Rutgers University, Piscataway, NJ 08854, USA.

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Assessment of pharmacologic area under the curve when baselines are variable.

Pharm Res 2011 May 14;28(5):1081-9. Epub 2011 Jan 14.

Biomedical Engineering Department, Rutgers University, 599 Taylor Road, Piscataway, New Jersey 08854, USA.

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May 2011
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Identification of a gene regulatory network necessary for the initiation of oligodendrocyte differentiation.

PLoS One 2011 Apr 7;6(4):e18088. Epub 2011 Apr 7.

Department of Neuroscience and Genetics and Genomic, Mount Sinai School of Medicine, New York, New York, United States of America.

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April 2011
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Pathway analysis of liver metabolism under stressed condition.

J Theor Biol 2011 Mar 14;272(1):131-40. Epub 2010 Dec 14.

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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March 2011
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A physiological model for autonomic heart rate regulation in human endotoxemia.

Shock 2011 Mar;35(3):229-39

Biomedical Engineering, Rutgers University, Piscataway.

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March 2011
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A quantitative model of thermal injury-induced acute inflammation.

Math Biosci 2011 Feb 11;229(2):135-48. Epub 2010 Aug 11.

Chemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854, USA.

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February 2011
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Metabolic flux determination in perfused livers by mass balance analysis: effect of fasting.

Biotechnol Bioeng 2010 Dec;107(5):825-35

Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA.

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December 2010
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Circadian signatures in rat liver: from gene expression to pathways.

BMC Bioinformatics 2010 Nov 1;11:540. Epub 2010 Nov 1.

Chemical and Biochemical Engineering Department, Rutgers University Piscataway, NJ 08854, USA.

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November 2010
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Transcriptional and metabolic flux profiling of triadimefon effects on cultured hepatocytes.

Toxicol Appl Pharmacol 2010 Nov 24;248(3):165-77. Epub 2010 Jul 24.

Dept. of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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November 2010
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Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: transcriptional dynamics and regulatory structures.

BMC Bioinformatics 2010 Oct 14;11:515. Epub 2010 Oct 14.

BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey, USA.

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October 2010
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Multiscale model for the assessment of autonomic dysfunction in human endotoxemia.

Physiol Genomics 2010 Jun 16;42(1):5-19. Epub 2010 Mar 16.

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June 2010
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A new symbolic representation for the identification of informative genes in replicated microarray experiments.

OMICS 2010 Jun;14(3):239-48

Biomedical Engineering Department, Rutgers University, Piscataway, New Jersey 08854, USA.

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June 2010
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Modeling the influence of circadian rhythms on the acute inflammatory response.

J Theor Biol 2010 Jun 20;264(3):1068-76. Epub 2010 Mar 20.

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Importance of replication in analyzing time-series gene expression data: corticosteroid dynamics and circadian patterns in rat liver.

BMC Bioinformatics 2010 May 26;11:279. Epub 2010 May 26.

BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey, USA.

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May 2010
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Agent-based modeling of endotoxin-induced acute inflammatory response in human blood leukocytes.

PLoS One 2010 Feb 18;5(2):e9249. Epub 2010 Feb 18.

Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey, United States of America.

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February 2010
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Cytoskeleton-based forecasting of stem cell lineage fates.

Proc Natl Acad Sci U S A 2010 Jan 18;107(2):610-5. Epub 2009 Dec 18.

Department of Biomedical Engineering, New Jersey Center for Biomaterials, Rutgers University, Piscataway, NJ 08854, USA.

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January 2010
6 Reads
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Identification of global transcriptional dynamics.

PLoS One 2009 Jul 10;4(7):e5992. Epub 2009 Jul 10.

Biomedical Engineering Department, Rutgers University, NJ, USA.

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July 2009
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In silico simulation of corticosteroids effect on an NFkB- dependent physicochemical model of systemic inflammation.

PLoS One 2009 10;4(3):e4706. Epub 2009 Mar 10.

Biomedical Engineering, Rutgers University, Piscataway, New Jersey, United States of America.

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June 2009
29 Citations
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Unsupervised selection of highly coexpressed and noncoexpressed genes using a consensus clustering approach.

OMICS 2009 Jun;13(3):219-37

BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey 08854, USA.

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June 2009
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Assessing and selecting gene expression signals based upon the quality of the measured dynamics.

BMC Bioinformatics 2009 Feb 10;10:55. Epub 2009 Feb 10.

Biomedical Engineering Department, Rutgers University, Piscataway, NJ, USA.

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February 2009
2.580 Impact Factor

Transcription factor network reconstruction using the living cell array.

J Theor Biol 2009 Feb 22;256(3):393-407. Epub 2008 Oct 22.

Department of Biomedical Engineering, Rutgers University, 599 Taylor Road, Piscataway, NJ 08854, USA.

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February 2009
6 Citations
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Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect.

Toxicol Appl Pharmacol 2009 Jan 7;234(2):156-65. Epub 2008 Oct 7.

Environmental and Occupational Health Sciences Institute (EOHSI), a Joint Institute of UMDNJ-RW Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA.

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January 2009
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Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle.

Am J Physiol Regul Integr Comp Physiol 2008 Oct 30;295(4):R1031-47. Epub 2008 Jul 30.

Dept. of Biological Sciences, State Univ. of New York at Buffalo, Buffalo, NY 14260, USA.

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October 2008
6 Reads
25 Citations
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Circadian variations in rat liver gene expression: relationships to drug actions.

J Pharmacol Exp Ther 2008 Sep 18;326(3):700-16. Epub 2008 Jun 18.

Department of Biological Sciences, 107 Hochstetter Hall, State University of New York at Buffalo, Buffalo, NY 14260, USA.

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September 2008
3 Reads
25 Citations
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Assessing the information content of short time series expression data.

Conf Proc IEEE Eng Med Biol Soc 2006;2006:5535-8

Rutgers University, Piscataway, NJ 08845, USA.

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March 2008
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Control of hepatic differentiation via cellular aggregation in an alginate microenvironment.

Biotechnol Bioeng 2007 Oct;98(3):631-44

Department of Biomedical Engineering, Rutgers University, 617 Bowser Road, Piscataway, New Jersey 08854, USA.

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October 2007
21 Reads
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Context specific transcription factor prediction.

Ann Biomed Eng 2007 Jun 22;35(6):1053-67. Epub 2007 Mar 22.

Biomedical Engineering Department, Rutgers University, Piscataway, NJ 08854, USA.

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June 2007
2 Reads
3 Citations
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Bioinformatics analysis of the early inflammatory response in a rat thermal injury model.

BMC Bioinformatics 2007 Jan 10;8:10. Epub 2007 Jan 10.

Biomedical Engineering Department, Rutgers University, Piscataway, NJ, USA.

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January 2007
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Marianthi G Ierapetritou

the State University of New Jersey

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Francois Berthiaume
Francois Berthiaume

Rutgers University

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Princeton University

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Steve E Calvano
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Robert Wood Johnson Medical School

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Richard R Almon
Richard R Almon

State University of New York at Buffalo

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University of Medicine and Dentistry of New Jersey

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