Inigo Martincorena

Inigo Martincorena

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Inigo Martincorena

Inigo Martincorena

Publications by authors named "Inigo Martincorena"

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52Publications

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Somatic evolution and global expansion of an ancient transmissible cancer lineage.

Science 2019 08;365(6452)

Transmissible Cancer Group, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1126/science.aau9923DOI Listing
August 2019

Somatic mutation and clonal expansions in human tissues.

Genome Med 2019 05 28;11(1):35. Epub 2019 May 28.

Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.

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http://dx.doi.org/10.1186/s13073-019-0648-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537184PMC
May 2019

Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways.

Cancer Cell 2019 Mar;35(3):441-456.e8

Research Department of Pathology, Cancer Institute, University College London, London WC1E 6BT, UK; Department of Cellular and Molecular Pathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex HA7 4LP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428691PMC
March 2019

Recurrent histone mutations in T-cell acute lymphoblastic leukaemia.

Br J Haematol 2019 Feb 30;184(4):676-679. Epub 2018 Mar 30.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, UK.

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http://dx.doi.org/10.1111/bjh.15155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766952PMC
February 2019

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nature 2019 02;566(7742):E1

Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.

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http://www.nature.com/articles/s41586-019-0883-2
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http://dx.doi.org/10.1038/s41586-019-0883-2DOI Listing
February 2019

Prediction of acute myeloid leukaemia risk in healthy individuals.

Nature 2018 07 9;559(7714):400-404. Epub 2018 Jul 9.

Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41586-018-0317-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485381PMC
July 2018

Cancer-mutation network and the number and specificity of driver mutations.

Proc Natl Acad Sci U S A 2018 06 12;115(26):E6010-E6019. Epub 2018 Jun 12.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894;

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http://dx.doi.org/10.1073/pnas.1803155115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042135PMC
June 2018

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

Nat Genet 2018 05 16;50(5):682-692. Epub 2018 Apr 16.

The Institute of Cancer Research, London, UK.

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http://www.nature.com/articles/s41588-018-0086-z
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http://dx.doi.org/10.1038/s41588-018-0086-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372064PMC
May 2018

Pathway-based dissection of the genomic heterogeneity of cancer hallmarks' acquisition with SLAPenrich.

Sci Rep 2018 04 30;8(1):6713. Epub 2018 Apr 30.

European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, CB10 1SD, UK.

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http://dx.doi.org/10.1038/s41598-018-25076-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928049PMC
April 2018

Universal Patterns of Selection in Cancer and Somatic Tissues.

Cell 2017 Nov 19;171(5):1029-1041.e21. Epub 2017 Oct 19.

Wellcome Trust Sanger Institute, Hinxton CB10 1SA, Cambridgeshire, UK; Department of Haematology, University of Cambridge, Cambridge CB2 2XY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720395PMC
November 2017

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nature 2016 06 2;534(7605):47-54. Epub 2016 May 2.

Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature17676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910866PMC
June 2016

Genomic Classification and Prognosis in Acute Myeloid Leukemia.

N Engl J Med 2016 Jun;374(23):2209-2221

Cancer Genome Project, Wellcome Trust Sanger Institute (E.P., M.G., N.D.R., N.B., G.G., P.V.L., I.M., L.M., S.M., S.O., K.R., D.R.J., J.W.T., A.P.B., P.J.C.), and the European Bioinformatics Institute, European Molecular Biology Laboratory (EMBL-EBI) (M.G.), Hinxton, the Centre for Evolution and Cancer, Institute of Cancer Research, London (N.E.P., M.F.G.), and the Department of Haematology, University of Cambridge, Cambridge (N.B.) - all in the United Kingdom; the Departments of Epidemiology and Biostatistics and Cancer Biology, the Center for Molecular Oncology and the Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York (E.P.); the Department of Internal Medicine III, Ulm University, Ulm (L.B., V.I.G., P.P., K.D., R.F.S., H.D.), and the Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover (M.H., F.T., A.G.) - both in Germany; the Division of Hematology, Fondazione IRCCS, Istituto Nazionale dei Tumori, and Department of Oncology and Onco-Hematology, University of Milan, Milan (N.B.); the Department of Human Genetics, University of Leuven, Leuven, Belgium (P.V.L.); and the Department of Pathology, University of Otago, Christchurch, New Zealand (P.G., P.J.C.).

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http://dx.doi.org/10.1056/NEJMoa1516192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979995PMC
June 2016

Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer.

Elife 2016 05 17;5. Epub 2016 May 17.

Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.7554/eLife.14552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869914PMC
May 2016

Constrained positive selection on cancer mutations in normal skin.

Proc Natl Acad Sci U S A 2016 Mar 16;113(9):E1128-9. Epub 2016 Feb 16.

Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, United Kingdom; Department of Haematology, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

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http://www.pnas.org/content/113/9/E1128.full.pdf
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http://www.pnas.org/lookup/doi/10.1073/pnas.1600910113
Publisher Site
http://dx.doi.org/10.1073/pnas.1600910113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780655PMC
March 2016

Somatic mutation in cancer and normal cells.

Science 2015 Sep 24;349(6255):1483-9. Epub 2015 Sep 24.

Wellcome Trust Sanger Institute, Hinxton CB10 1SA, Cambridgeshire, UK. Department of Haematology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1126/science.aab4082DOI Listing
September 2015

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Science 2014 Aug;345(6196):1251343

Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.

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http://dx.doi.org/10.1126/science.1251343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380235PMC
August 2014

Non-random mutation: the evolution of targeted hypermutation and hypomutation.

Bioessays 2013 Feb 20;35(2):123-30. Epub 2012 Dec 20.

Cancer Research UK London Research Institute, London, UK.

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http://dx.doi.org/10.1002/bies.201200150DOI Listing
February 2013

Evidence of non-random mutation rates suggests an evolutionary risk management strategy.

Nature 2012 May;485(7396):95-8

EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SD, UK.

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http://dx.doi.org/10.1038/nature10995DOI Listing
May 2012

Lexical access changes in patients with multiple sclerosis: a two-year follow-up study.

J Clin Exp Neuropsychol 2011 Feb 10;33(2):169-75. Epub 2010 Sep 10.

Department of Neuroscience, CIMA University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1080/13803395.2010.499354DOI Listing
February 2011

The organization of local and distant functional connectivity in the human brain.

PLoS Comput Biol 2010 Jun 10;6(6):e1000808. Epub 2010 Jun 10.

Howard Hughes Medical Institute, Cambridge, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1000808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883589PMC
June 2010