Ingo Drexler

Ingo Drexler

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Ingo Drexler

Publications by authors named "Ingo Drexler"

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Corrigendum: Interleukin-2-Inducible T-Cell Kinase Deficiency-New Patients, New Insight?

Front Immunol 2018 1;9:2197. Epub 2018 Oct 1.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.02197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174291PMC
October 2018

The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation.

Eur J Immunol 2018 07 2;48(7):1137-1152. Epub 2018 May 2.

Department of Immunology, the Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1002/eji.201747378DOI Listing
July 2018

Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol.

J Gen Virol 2018 06 20;99(6):790-804. Epub 2018 Apr 20.

1​Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://www.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/jgv.0.001034DOI Listing
June 2018

Impact of the TAP-like transporter in antigen presentation and phagosome maturation.

Mol Immunol 2018 Jun 23. Epub 2018 Jun 23.

Institut National de la Sante et de la Recherche Médicale, Unité 1151; Université Paris Descartes, Faculté de médecine; Centre National de la Recherche Scientifique, UMR8253; 149 rue de Sèvres, 75743 Paris Cedex 15, France. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2018.06.268DOI Listing
June 2018

Interleukin-2-Inducible T-Cell Kinase Deficiency-New Patients, New Insight?

Front Immunol 2018 8;9:979. Epub 2018 May 8.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.00979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951928PMC
May 2018

Active dissemination of cellular antigens by DCs facilitates CD8 T-cell priming in lymph nodes.

Eur J Immunol 2017 10;47(10):1802-1818

Department of Immunology and Veterinary Services, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1002/eji.201747042DOI Listing
October 2017

Immune Protection by a Cytomegalovirus Vaccine Vector Expressing a Single Low-Avidity Epitope.

J Immunol 2017 09 2;199(5):1737-1747. Epub 2017 Aug 2.

Research Group Immune Aging and Chronic Infections, Department of Vaccinology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany;

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http://dx.doi.org/10.4049/jimmunol.1602115DOI Listing
September 2017

Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection.

J Exp Med 2016 07 4;213(8):1571-87. Epub 2016 Jul 4.

Departement de Pathologie et Immunologie, Centre Medical Universitaire, University of Geneva, 1211 Geneva, Switzerland Division of Clinical Pathology, Geneva University Hospital, 1211 Geneva, Switzerland

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http://dx.doi.org/10.1084/jem.20151916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986533PMC
July 2016

Gene Expression Driven by a Strong Viral Promoter in MVA Increases Vaccination Efficiency by Enhancing Antibody Responses and Unmasking CD8⁺ T Cell Epitopes.

Vaccines (Basel) 2014 Jul 22;2(3):581-600. Epub 2014 Jul 22.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany.

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http://dx.doi.org/10.3390/vaccines2030581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494220PMC
July 2014

Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells.

Immunity 2014 Jul;41(1):116-26

Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich 81675, Germany; Focus Group "Clinical Cell Processing and Purification," Institute for Advanced Study, TUM, Munich 81675, Germany; Clinical Cooperation Groups "Antigen-specific Immunotherapy" and "Immune-Monitoring," Helmholtz Center Munich (Neuherberg), TUM, Munich 81675, Germany; German Center for Infection Research (DZIF), Munich 81675, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.05.018DOI Listing
July 2014

Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production.

Nat Immunol 2014 Jun 28;15(6):538-45. Epub 2014 Apr 28.

Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1038/ni.2888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309842PMC
June 2014

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.

PLoS Pathog 2014 Apr 17;10(4):e1003989. Epub 2014 Apr 17.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America; Lucille Castori Center for Microbes, Inflammation and Cancer, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990710PMC
April 2014

α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets.

Acta Neuropathol Commun 2014 Mar 7;2:27. Epub 2014 Mar 7.

Klinikum rechts der Isar, Department of Neurology, Technische Universität München, Ismaninger Str, 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1186/2051-5960-2-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029267PMC
March 2014

Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines.

Int J Oncol 2012 Aug 14;41(2):733-44. Epub 2012 May 14.

Institute of Pathology, Technische Universität München, Klinikum rechts der Isar, Munich, Germany.

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http://dx.doi.org/10.3892/ijo.2012.1479DOI Listing
August 2012

Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines.

J Cancer Res Clin Oncol 2012 May;138(5):843-58

Institut für Allgemeine Pathologie und Pathologische Anatomie, Technische Universität München, Klinikum rechts der Isar, Trogerstr. 18, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00432-011-1128-4DOI Listing
May 2012

Rapid in vivo conversion of effector T cells into Th2 cells during helminth infection.

J Immunol 2012 Jan 7;188(2):615-23. Epub 2011 Dec 7.

Institute for Immunology, Ludwig Maximilian University, 80336 Munich, Germany.

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http://dx.doi.org/10.4049/jimmunol.1101164DOI Listing
January 2012

Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction.

J Immunol 2011 Sep 17;187(6):3186-97. Epub 2011 Aug 17.

Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.1101649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169715PMC
September 2011

Interplay between modified vaccinia virus Ankara and dendritic cells: phenotypic and functional maturation of bystander dendritic cells.

J Virol 2011 Jun 16;85(11):5532-45. Epub 2011 Mar 16.

Centro Nacional de Referencia para el SIDA, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1128/JVI.02267-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094969PMC
June 2011

Antigen delivery to plasmacytoid dendritic cells via BST2 induces protective T cell-mediated immunity.

J Immunol 2011 Jun 9;186(12):6718-25. Epub 2011 May 9.

II Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, D-81675 München, Germany.

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http://dx.doi.org/10.4049/jimmunol.1004029DOI Listing
June 2011

Modified vaccinia virus Ankara exerts potent immune modulatory activities in a murine model.

PLoS One 2010 Jun 30;5(6):e11400. Epub 2010 Jun 30.

Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011400PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900180PMC
June 2010

Cutting edge: memory CD8 T cell compartment grows in size with immunological experience but nevertheless can lose function.

J Immunol 2009 Dec 4;183(11):6898-902. Epub 2009 Nov 4.

Institute for Medical Microbiology, Immunology, and Hygiene, Technical University Munich, 81675 Munich, Germany.

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http://dx.doi.org/10.4049/jimmunol.0902454DOI Listing
December 2009

Differential capacity of chaperone-rich lysates in cross-presenting human endogenous and exogenous melanoma differentiation antigens.

Int J Hyperthermia 2008 Dec;24(8):623-37

Clinical Cooperation Group Hyperthermia, Helmholtz Zentrum München-German Research Center for Environmental Health, 81377 Munich, Germany.

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http://dx.doi.org/10.1080/02656730802213384DOI Listing
December 2008

Cross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines.

J Virol 2007 Nov 15;81(21):11925-36. Epub 2007 Aug 15.

GSF-Institute for Molecular Virology, Schneckenburgerstrasse 8, D-81675 Munich, Germany.

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http://dx.doi.org/10.1128/JVI.00903-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168793PMC
November 2007

A novel cytosolic class I antigen-processing pathway for endoplasmic-reticulum-targeted proteins.

EMBO Rep 2007 Oct 14;8(10):945-51. Epub 2007 Sep 14.

Division of Immunology, Department of Biology, Postbox M661, Universitatstrasse 10, University of Constance, Konstanz D-78457, Germany.

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http://dx.doi.org/10.1038/sj.embor.7401065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002554PMC
October 2007

Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccination.

J Exp Med 2007 Sep 20;204(9):2187-98. Epub 2007 Aug 20.

Institute of Molecular Virology, Antigen-specific Immunotherapy Clinical Cooperation Group, National Research Center for Environment and Health, 81675 Munich, Germany.

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http://dx.doi.org/10.1084/jem.20070489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118691PMC
September 2007

The poxviral scrapin MV-LAP requires a myxoma viral infection context to efficiently downregulate MHC-I molecules.

Virology 2005 Dec 23;343(2):171-8. Epub 2005 Sep 23.

UMR 1225 Interactions Hôtes Agents pathogènes, INRA/ENVT, Ecole Nationale Vétérinaire de Toulouse, 23 chemin des Capelles, BP87614, 31076 Toulouse cedex 03, France.

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http://dx.doi.org/10.1016/j.virol.2005.07.032DOI Listing
December 2005

Melanoma patients respond to a new HLA-A*01-presented antigenic ligand derived from a multi-epitope region of melanoma antigen TRP-2.

Int J Cancer 2005 Oct;116(6):944-8

Skin Cancer Unit of the German Cancer Research Center at the University Hospital of Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1002/ijc.21132DOI Listing
October 2005

Modified vaccinia virus Ankara as antigen delivery system: how can we best use its potential?

Curr Opin Biotechnol 2004 Dec;15(6):506-12

Institute for Molecular Virology, München, Germany.

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http://dx.doi.org/10.1016/j.copbio.2004.09.001DOI Listing
December 2004

Construction and isolation of recombinant MVA.

Methods Mol Biol 2004 ;269:77-100

Institute of Molecular Virology, GSF-Research Center and Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1385/1-59259-789-0:077DOI Listing
August 2004

Partial tyrosinase-specific self tolerance by HLA-A*0201-restricted cytotoxic T lymphocytes in mice and man.

Int J Cancer 2004 Feb;108(4):571-9

Department of Hematology and Oncology, Johannes Gutenberg-University, Mainz, Germany.

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http://dx.doi.org/10.1002/ijc.11602DOI Listing
February 2004

HER-2/neu-mediated regulation of components of the MHC class I antigen-processing pathway.

Cancer Res 2004 Jan;64(1):215-20

Third Department of Internal Medicine and Pathology, Johannes Gutenberg-University, Mainz, Germany.

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January 2004

Functional role of human leukocyte antigen-G up-regulation in renal cell carcinoma.

Cancer Res 2003 Jul;63(14):4107-11

Third Department of Internal Medicine, Johannes Gutenberg University, 55101 Mainz, Germany.

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July 2003

Impaired transporter associated with antigen processing (TAP) function attributable to a single amino acid alteration in the peptide TAP subunit TAP1.

J Immunol 2003 Jan;170(2):941-6

Third Department of Internal Medicine, Johannes Gutenberg-University, Mainz, Germany.

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http://dx.doi.org/10.4049/jimmunol.170.2.941DOI Listing
January 2003

Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines.

Proc Natl Acad Sci U S A 2003 Jan 23;100(1):217-22. Epub 2002 Dec 23.

GSF-Institut für Molekulare Virologie, Institut für Virologie, Technische Universität München (TUM), Trogerstrasse 4 b, Germany.

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http://dx.doi.org/10.1073/pnas.262668999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140931PMC
January 2003

The use of HLA-A*0201-transfected K562 as standard antigen-presenting cells for CD8(+) T lymphocytes in IFN-gamma ELISPOT assays.

J Immunol Methods 2002 Jan;259(1-2):95-110

Third Department of Medicine, Hematology and Oncology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, D-55101, Mainz, Germany.

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January 2002