Inge Seim

Inge Seim

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Inge Seim

Publications by authors named "Inge Seim"

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Distinct evolution of toll-like receptor signaling pathway genes in cetaceans.

Genes Genomics 2019 12 18;41(12):1417-1430. Epub 2019 Sep 18.

Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, 210023, Jiangsu, China.

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http://dx.doi.org/10.1007/s13258-019-00861-3DOI Listing
December 2019

The long non-coding RNA GHSROS facilitates breast cancer cell migration and orthotopic xenograft tumour growth.

Int J Oncol 2019 Dec 4;55(6):1223-1236. Epub 2019 Oct 4.

Ghrelin Research Group, Translational Research Institute-Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland 4102, Australia.

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http://dx.doi.org/10.3892/ijo.2019.4891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831199PMC
December 2019

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity.

Oncogene 2019 Nov 19;38(48):7294-7310. Epub 2019 Aug 19.

Inflammatory Disease Biology and Therapeutics Group, Mater Research Institute, The University of Queensland, Translational Research Institute, Woolloongabba, Brisbane, QLD, 4102, Australia.

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http://dx.doi.org/10.1038/s41388-019-0951-yDOI Listing
November 2019

Accelerated evolution and diversifying selection drove the adaptation of cetacean bone microstructure.

BMC Evol Biol 2019 10 24;19(1):194. Epub 2019 Oct 24.

Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, 210023, China.

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http://dx.doi.org/10.1186/s12862-019-1509-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813995PMC
October 2019

Contraction of the ROS Scavenging Enzyme Glutathione -Transferase Gene Family in Cetaceans.

G3 (Bethesda) 2019 07 9;9(7):2303-2315. Epub 2019 Jul 9.

Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, Jiangsu, 210046, China

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http://dx.doi.org/10.1534/g3.119.400224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643896PMC
July 2019

Limited short-term effects on human prostate cancer xenograft growth and epidermal growth factor receptor gene expression by the ghrelin receptor antagonist [D-Lys]-GHRP-6.

Endocrine 2019 05 2;64(2):393-405. Epub 2018 Nov 2.

Ghrelin Research Group, Institute of Health and Biomedical Innovation, Translational Research Institute and School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.

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http://link.springer.com/10.1007/s12020-018-1796-9
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http://dx.doi.org/10.1007/s12020-018-1796-9DOI Listing
May 2019

RadAA: A Command-line Tool for Identification of Radical Amino Acid Changes in Multiple Sequence Alignments.

Mol Inform 2019 01 17;38(1-2):e1800057. Epub 2018 Jul 17.

Comparative and Endocrine Biology Laboratory, Translational Research Institute - Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, 37 Kent St, 4102, Woolloongabba, Australia.

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http://dx.doi.org/10.1002/minf.201800057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585820PMC
January 2019

Transparency on scientific instruments.

EMBO Rep 2018 06 22;19(6). Epub 2018 May 22.

School of Biomedical Sciences, Queensland University of Technology, Brisbane, Qld, Australia.

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http://dx.doi.org/10.15252/embr.201845853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989778PMC
June 2018

Adaptive Evolution of Energy Metabolism-Related Genes in Hypoxia-Tolerant Mammals.

Front Genet 2017 7;8:205. Epub 2017 Dec 7.

Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.

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http://dx.doi.org/10.3389/fgene.2017.00205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725996PMC
December 2017

Whole-Genome Sequence of the Metastatic PC3 and LNCaP Human Prostate Cancer Cell Lines.

G3 (Bethesda) 2017 06 7;7(6):1731-1741. Epub 2017 Jun 7.

Comparative and Endocrine Biology Laboratory, Translational Research Institute-Institute of Health and Biomedical Innovation, Queensland University of Technology, Woolloongabba, Brisbane, Queensland 4102, Australia.

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http://dx.doi.org/10.1534/g3.117.039909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473753PMC
June 2017

MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance.

Int J Cancer 2017 05 28;140(10):2351-2363. Epub 2017 Feb 28.

Inflammatory Disease Biology and Therapeutics Group, Mater Research Institute - The University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.

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http://doi.wiley.com/10.1002/ijc.30651
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http://dx.doi.org/10.1002/ijc.30651DOI Listing
May 2017

Insights from engraftable immunodeficient mouse models of hyperinsulinaemia.

Sci Rep 2017 03 28;7(1):491. Epub 2017 Mar 28.

Ghrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/s41598-017-00443-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428450PMC
March 2017

Gene expression signatures of human cell and tissue longevity.

NPJ Aging Mech Dis 2016 7;2:16014. Epub 2016 Jul 7.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/npjamd.2016.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514998PMC
July 2016

Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide.

Endocrine 2016 Jun 20;52(3):609-17. Epub 2016 Jan 20.

Comparative and Endocrine Biology Laboratory, Translational Research Institute-Institute of Health and Biomedical Innovation (TRI-IHBI), Queensland University of Technology, Woolloongabba, QLD, 4102, Australia.

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http://dx.doi.org/10.1007/s12020-015-0848-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879156PMC
June 2016

Fusion transcript loci share many genomic features with non-fusion loci.

BMC Genomics 2015 Dec 1;16:1021. Epub 2015 Dec 1.

Australian Prostate Cancer Research Centre - Queensland, Translational Research Institute, Brisbane, Australia.

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http://dx.doi.org/10.1186/s12864-015-2235-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667522PMC
December 2015

Convergent evolution of marine mammals is associated with distinct substitutions in common genes.

Sci Rep 2015 Nov 9;5:16550. Epub 2015 Nov 9.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://www.nature.com/articles/srep16550
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http://dx.doi.org/10.1038/srep16550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637874PMC
November 2015

Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins.

Proc Natl Acad Sci U S A 2015 Aug 10;112(34):10685-90. Epub 2015 Aug 10.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1505315112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553801PMC
August 2015

Comparative analysis reveals loss of the appetite-regulating peptide hormone ghrelin in falcons.

Gen Comp Endocrinol 2015 May 8;216:98-102. Epub 2014 Dec 8.

Ghrelin Research Group, Translational Research Institute - Institute of Health and Biomedical Innovation, Queensland University of Technology, 37 Kent St., Woolloongabba, Queensland 4102, Australia; Australian Prostate Cancer Research Centre - Queensland, Queensland University of Technology and Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ygcen.2014.11.016DOI Listing
May 2015

The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal.

Aging (Albany NY) 2014 Oct;6(10):879-99

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247388PMC
http://dx.doi.org/10.18632/aging.100699DOI Listing
October 2014

Turtle ghrelin.

Nat Genet 2014 Jun;46(6):525-6

1] Ghrelin Research Group, Translational Research Institute-Institute of Health and Biomedical Innovation, Queensland University of Technology, Woolloongabba, Queensland, Australia. [2] Australian Prostate Cancer Research Centre-Queensland, Queensland University of Technology and Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.2964DOI Listing
June 2014

Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines.

Int J Oncol 2013 Aug 30;43(2):566-74. Epub 2013 May 30.

Ghrelin Research Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.3892/ijo.2013.1969DOI Listing
August 2013

Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo.

Am J Physiol Endocrinol Metab 2013 Jul 4;305(2):E305-13. Epub 2013 Jun 4.

School of Biomedical Sciences, University of Queensland, St. Lucia, Queensland, Australia.

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http://dx.doi.org/10.1152/ajpendo.00156.2013DOI Listing
July 2013

Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin.

Reprod Biol Endocrinol 2013 Jul 23;11:70. Epub 2013 Jul 23.

Ghrelin Research Group, Translational Research Institute - Institute of Health and Biomedical Innovation, Queensland University of Technology, 37 Kent St, Woolloongabba, Queensland, 4102, Australia.

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http://dx.doi.org/10.1186/1477-7827-11-70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724588PMC
July 2013

Cloning of a novel insulin-regulated ghrelin transcript in prostate cancer.

J Mol Endocrinol 2013 Apr 15;50(2):179-91. Epub 2013 Feb 15.

Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology, Kelvin Grove, Brisbane, Queensland 4059, Australia.

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http://dx.doi.org/10.1530/JME-12-0150DOI Listing
April 2013

The ghrelin axis--does it have an appetite for cancer progression?

Endocr Rev 2012 Dec 23;33(6):849-91. Epub 2012 Jul 23.

Ghrelin Research Group, Institute of Health and Biomedical Innovation, Queensland University of Technology and Australian Prostate Cancer Research Centre-Queensland, Brisbane, Queensland 4001, Australia.

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http://dx.doi.org/10.1210/er.2011-1007DOI Listing
December 2012

Ghrelin and the brain-gut axis as a pharmacological target for appetite control.

Curr Pharm Des 2012 ;18(6):768-75

Ghrelin Research Group, Institute of Health and Biomedical Innovation, 60 Musk Avenue, Kelvin Grove, Queensland, 4059, Australia.

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http://dx.doi.org/10.2174/138161212799277806DOI Listing
July 2012

Irritable bowel syndrome: the role of gut neuroendocrine peptides.

Front Biosci (Elite Ed) 2012 Jun 1;4:2783-800. Epub 2012 Jun 1.

Section for Gastroenterology, Department of Medicine, Stord Helse-Fonna Hospital, Norway.

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http://dx.doi.org/10.2741/e583DOI Listing
June 2012

The expanding roles of the ghrelin-gene derived peptide obestatin in health and disease.

Mol Cell Endocrinol 2011 Jun 1;340(1):111-7. Epub 2011 Apr 1.

Queensland University of Technology, Queensland, Brisbane, Australia.

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http://dx.doi.org/10.1016/j.mce.2011.03.018DOI Listing
June 2011

Ghrelin and cancer.

Mol Cell Endocrinol 2011 Jun 25;340(1):65-9. Epub 2011 May 25.

Queensland University of Technology, Brisbane, Australia.

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http://dx.doi.org/10.1016/j.mce.2011.04.013DOI Listing
June 2011

Ghrelin axis genes, peptides and receptors: recent findings and future challenges.

Mol Cell Endocrinol 2011 Jun 25;340(1):3-9. Epub 2011 May 25.

Queensland University of Technology, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1016/j.mce.2011.05.002DOI Listing
June 2011

Expression and in vitro functions of the ghrelin axis in endometrial cancer.

Horm Cancer 2010 Oct;1(5):245-55

Department of Physiology and Pharmacology, School of Biomedical Sciences, The University of Queensland, Brisbane QLD 4072, Australia.

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http://link.springer.com/10.1007/s12672-010-0047-1
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http://dx.doi.org/10.1007/s12672-010-0047-1DOI Listing
October 2010

A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells.

RNA 2010 Jun 20;16(6):1156-66. Epub 2010 Apr 20.

Australian Prostate Cancer Research Centre-Queensland, Queensland University of Technology and Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia.

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http://rnajournal.cshlp.org/cgi/doi/10.1261/rna.2019810
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http://dx.doi.org/10.1261/rna.2019810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874168PMC
June 2010

Ghrelin gene-related peptides: multifunctional endocrine / autocrine modulators in health and disease.

Clin Exp Pharmacol Physiol 2010 Jan 29;37(1):125-31. Epub 2009 Jun 29.

Institute of Health and Biomedical Innovation and School of Life Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1111/j.1440-1681.2009.05241.xDOI Listing
January 2010

New insights into the molecular complexity of the ghrelin gene locus.

Cytokine Growth Factor Rev 2009 Aug 8;20(4):297-304. Epub 2009 Aug 8.

Institute of Health and Biomedical Innovation and School of Life Sciences, Queensland University of Technology, Brisbane, QLD 4000, Australia.

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http://dx.doi.org/10.1016/j.cytogfr.2009.07.006DOI Listing
August 2009

The proximal first exon architecture of the murine ghrelin gene is highly similar to its human orthologue.

BMC Res Notes 2009 May 9;2:85. Epub 2009 May 9.

Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia.

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http://dx.doi.org/10.1186/1756-0500-2-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689246PMC
May 2009

Complex organisation and structure of the ghrelin antisense strand gene GHRLOS, a candidate non-coding RNA gene.

BMC Mol Biol 2008 Oct 28;9:95. Epub 2008 Oct 28.

Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia.

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http://dx.doi.org/10.1186/1471-2199-9-95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621237PMC
October 2008

Revised genomic structure of the human ghrelin gene and identification of novel exons, alternative splice variants and natural antisense transcripts.

BMC Genomics 2007 Aug 30;8:298. Epub 2007 Aug 30.

Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia.

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http://dx.doi.org/10.1186/1471-2164-8-298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014779PMC
August 2007