Inge Marie Svane

Inge Marie Svane

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Inge Marie Svane

Publications by authors named "Inge Marie Svane"

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Differential effects of corticosteroids and anti-TNF on tumor-specific immune responses: implications for the management of irAEs.

Int J Cancer 2019 Sep 7;145(5):1408-1413. Epub 2019 Jan 7.

Department of Hematology, Center for Cancer Immune Therapy, Herlev and Gentofte Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1002/ijc.32080DOI Listing
September 2019

Peripheral memory T cells specific for Arginase-1.

Cell Mol Immunol 2019 May 10. Epub 2019 May 10.

Center for Cancer Immune Therapy (CCIT), Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1038/s41423-019-0231-3DOI Listing
May 2019

The real-world impact of modern treatments on the survival of patients with metastatic melanoma.

Eur J Cancer 2019 Feb 31;108:25-32. Epub 2018 Dec 31.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, Herlev, Denmark; Department of Oncology, Herlev Hospital, Herlev, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049183153
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http://dx.doi.org/10.1016/j.ejca.2018.12.002DOI Listing
February 2019

Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.

Br J Cancer 2019 Feb 5;120(4):424-434. Epub 2019 Feb 5.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://www.nature.com/articles/s41416-019-0384-y
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http://dx.doi.org/10.1038/s41416-019-0384-yDOI Listing
February 2019

Principles of adoptive T cell therapy in cancer.

Semin Immunopathol 2019 01 5;41(1):49-58. Epub 2018 Sep 5.

Center for Cancer Immune Therapy, Department of Hematology, Copenhagen University Hospital, Entrance 81, Floor 05, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00281-018-0703-zDOI Listing
January 2019

Correction: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

Oncotarget 2018 11 9;9(88):35870. Epub 2018 Nov 9.

Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.18632/oncotarget.26359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254673PMC
November 2018

Immunoprofiles of colorectal cancer from Lynch syndrome.

Oncoimmunology 2019 26;8(1):e1515612. Epub 2018 Sep 26.

The Danish HNPCC Register, Clinical Research Centre, Copenhagen University Hospital, Hvidovre Hospital, Hvidovre, Denmark.

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https://www.tandfonline.com/doi/full/10.1080/2162402X.2018.1
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http://dx.doi.org/10.1080/2162402X.2018.1515612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287783PMC
September 2018

Cancer immunotherapy in patients with brain metastases.

Cancer Immunol Immunother 2018 May 8;67(5):703-711. Epub 2018 Mar 8.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-018-2146-8DOI Listing
May 2018

[Cancer immunotherapy].

Ugeskr Laeger 2018 May;180(21)

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May 2018

Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes.

Leuk Lymphoma 2018 04 9;59(4):973-977. Epub 2017 Aug 9.

a Department of Hematology , Zealand University Hospital , Roskilde , Denmark.

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http://dx.doi.org/10.1080/10428194.2017.1359743DOI Listing
April 2018

Checkpoint inhibitors in breast cancer - Current status.

Cancer Treat Rev 2018 Feb 14;63:122-134. Epub 2017 Dec 14.

Department of Oncology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev Ringvej 75, DK-2730 Herlev, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03057372173021
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http://dx.doi.org/10.1016/j.ctrv.2017.12.008DOI Listing
February 2018

T-cell Responses in the Microenvironment of Primary Renal Cell Carcinoma-Implications for Adoptive Cell Therapy.

Cancer Immunol Res 2018 02 4;6(2):222-235. Epub 2018 Jan 4.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0467DOI Listing
February 2018

Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab.

Oncoimmunology 2018 1;7(5):e1424674. Epub 2018 Feb 1.

Institute for Inflammation Research, Center for Rheumatology and Spine Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/2162402X.2018.1424674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927482PMC
February 2018

Large-Scale mRNA Transfection of Dendritic Cells by Electroporation in Continuous Flow Systems.

Methods Mol Biol 2016 ;1428:151-61

Department of Micro- and Nanotechnology, DTU Nanotech, Technical University of Denmark, Ørsteds Plads 345B, 2800, Kgs. Lyngby, Denmark.

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http://dx.doi.org/10.1007/978-1-4939-3625-0_10DOI Listing
December 2017

Immune Monitoring Using mRNA-Transfected Dendritic Cells.

Methods Mol Biol 2016 ;1428:245-59

Department of Haematology, Center for Cancer Immune Therapy, Copenhagen University Hospital Herlev, Herlev Ringvej 75, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/978-1-4939-3625-0_16DOI Listing
December 2017

Transfection of Tumor-Infiltrating T Cells with mRNA Encoding CXCR2.

Methods Mol Biol 2016 ;1428:261-76

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Copenhagen University Hospital Herlev, Herlev Ringvej 75, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/978-1-4939-3625-0_17DOI Listing
December 2017

Frequent adaptive immune responses against arginase-1.

Oncoimmunology 2018 26;7(3):e1404215. Epub 2017 Dec 26.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1080/2162402X.2017.1404215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790367PMC
December 2017

Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.

Nat Commun 2017 11 23;8(1):1738. Epub 2017 Nov 23.

Division of Oncology and Pathology, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Scheelegatan 2, Medicon Village, 22185, Lund, Sweden.

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http://dx.doi.org/10.1038/s41467-017-01460-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701046PMC
November 2017

PD-1 Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer.

Clin Cancer Res 2017 Oct 5;23(19):5779-5788. Epub 2017 Jul 5.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1692DOI Listing
October 2017

Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model.

Nat Commun 2017 09 27;8(1):707. Epub 2017 Sep 27.

From the Sahlgrenska Translational Melanoma Group, Institute of Clinical Science, Departments of Surgery and Oncology, Sahlgrenska Cancer Center at University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, 405 30, Sweden.

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http://dx.doi.org/10.1038/s41467-017-00786-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617838PMC
September 2017

Indoleamine 2,3-dioxygenase and survivin peptide vaccine combined with temozolomide in metastatic melanoma.

Stem Cell Investig 2017 21;4:77. Epub 2017 Sep 21.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.21037/sci.2017.08.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639040PMC
September 2017

Clinical Impact of the Number of Treatment Cycles in First-Line Docetaxel for Patients With Metastatic Castration-Resistant Prostate Cancer.

Clin Genitourin Cancer 2017 04 8;15(2):e281-e287. Epub 2016 Sep 8.

Department of Oncology, Herlev University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1016/j.clgc.2016.08.019DOI Listing
April 2017

Cancer immunotherapy in patients with preexisting autoimmune disorders.

Semin Immunopathol 2017 04 11;39(3):333-337. Epub 2016 Oct 11.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00281-016-0595-8DOI Listing
April 2017

Dendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II study.

Cytotherapy 2017 04 15;19(4):500-513. Epub 2017 Feb 15.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark; Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2017.01.007DOI Listing
April 2017

Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

Oncotarget 2017 04;8(16):27062-27074

Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.18632/oncotarget.16003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432318PMC
April 2017

The majority of patients with metastatic melanoma are not represented in pivotal phase III immunotherapy trials.

Eur J Cancer 2017 03 12;74:89-95. Epub 2017 Feb 12.

Center for Cancer Immune Therapy, Department of Hematology, Herlev, Denmark; Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S09598049173002
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http://dx.doi.org/10.1016/j.ejca.2016.12.017DOI Listing
March 2017

Predictors of Chemotherapy-Induced Toxicity and Treatment Outcomes in Elderly Versus Younger Patients With Metastatic Castration-Resistant Prostate Cancer.

Clin Genitourin Cancer 2016 12 24;14(6):e559-e568. Epub 2016 Mar 24.

Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1016/j.clgc.2016.03.018DOI Listing
December 2016

The Danish Melanoma Database.

Clin Epidemiol 2016 25;8:543-548. Epub 2016 Oct 25.

Registry Support Centre (East) - Epidemiology and Biostatistics, Research Centre for Prevention and Health, Glostrup - Rigshospitalet, University of Copenhagen, Glostrup, Denmark.

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http://dx.doi.org/10.2147/CLEP.S99484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094525PMC
October 2016

Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma.

Hum Vaccin Immunother 2015 ;11(12):2790-5

a Center for Cancer Immune Therapy ; Department of Hematology; Herlev Hospital; Copenhagen University ; Copenhagen , Denmark.

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http://dx.doi.org/10.1080/21645515.2015.1075106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054777PMC
September 2016

Autocrine CCL19 blocks dendritic cell migration toward weak gradients of CCL21.

Cytotherapy 2016 09 14;18(9):1187-96. Epub 2016 Jul 14.

Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2016.06.010DOI Listing
September 2016

CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment.

Oncoimmunology 2016 30;5(11):e1238541. Epub 2016 Sep 30.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Copenhagen University Hospital, Herlev, Denmark; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/2162402X.2016.1238541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139648PMC
September 2016

Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen.

Clin Cancer Res 2016 08 22;22(15):3734-45. Epub 2016 Mar 22.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark. Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1879DOI Listing
August 2016

Safety, immune and clinical responses in metastatic melanoma patients vaccinated with a long peptide derived from indoleamine 2,3-dioxygenase in combination with ipilimumab.

Cytotherapy 2016 08;18(8):1043-55

Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Herlev, Denmark; Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2016.05.010DOI Listing
August 2016

[Treatment of BRAF-mutated metastatic melanoma].

Ugeskr Laeger 2016 Aug;178(35)

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August 2016

PD-L1 peptide co-stimulation increases immunogenicity of a dendritic cell-based cancer vaccine.

Oncoimmunology 2016 Aug 1;5(8):e1202391. Epub 2016 Jul 1.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Copenhagen University Hospital, Herlev, Denmark; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/2162402X.2016.1202391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007957PMC
August 2016

mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma.

Oncoimmunology 2016 8;5(9):e1207842. Epub 2016 Jul 8.

Center for Cancer Immune Therapy (CCIT), Department of Hematology, Copenhagen University Hospital, Herlev, Denmark; Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1080/2162402X.2016.1207842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048758PMC
July 2016

Immunological correlates of treatment and response in stage IV malignant melanoma patients treated with Ipilimumab.

Oncoimmunology 2016 Apr 25;5(4):e1100788. Epub 2015 Nov 25.

Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Herlev, Denmark; Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1080/2162402X.2015.1100788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839337PMC
April 2016

The controversial role of TNF in melanoma.

Oncoimmunology 2016 Apr 29;5(4):e1107699. Epub 2015 Oct 29.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark; Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1080/2162402X.2015.1107699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839341PMC
April 2016

Low-dose prednisolone in first-line docetaxel for patients with metastatic castration-resistant prostate cancer: is there a clinical benefit?

Urol Oncol 2015 Nov 5;33(11):494.e15-20. Epub 2015 Aug 5.

Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S10781439150033
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http://dx.doi.org/10.1016/j.urolonc.2015.06.022DOI Listing
November 2015

[Ipilimumab induced colitis].

Ugeskr Laeger 2015 11;177(46):V66773

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November 2015

Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05.

Cytometry A 2015 Oct 1;87(10):967-75. Epub 2015 Jun 1.

Department of Hematology, Center for Cancer Immune Therapy, Herlev University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/cyto.a.22689DOI Listing
October 2015

Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity.

Cancer Res 2015 Sep 16;75(18):3747-59. Epub 2015 Jul 16.

Center for Cancer Immune Therapy, Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark. Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://cancerres.aacrjournals.org/content/early/2015/07/16/0
Web Search
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-14-2956DOI Listing
September 2015

Broadening the repertoire of melanoma-associated T-cell epitopes.

Cancer Immunol Immunother 2015 May 18;64(5):609-20. Epub 2015 Feb 18.

Center for Cancer Immune Therapy, Department of Hematology, University Hospital Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-015-1664-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412285PMC
May 2015

Confinement dependent chemotaxis in two-photon polymerized linear migration constructs with highly definable concentration gradients.

Biomed Microdevices 2015 Apr;17(2):30

Department of Micro- and Nanotechnology, Technical University of Denmark, Ørsteds Plads 345E, 2800, Kgs. Lyngby, Denmark.

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http://dx.doi.org/10.1007/s10544-015-9937-xDOI Listing
April 2015

Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α.

Eur J Haematol 2015 Mar 24;94(3):227-34. Epub 2014 Sep 24.

Department of Haematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark; Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1111/ejh.12420DOI Listing
March 2015

The targeting of indoleamine 2,3 dioxygenase -mediated immune escape in cancer.

Basic Clin Pharmacol Toxicol 2015 Jan 13;116(1):19-24. Epub 2014 Oct 13.

Department of Haematology and Oncology, Center for Cancer ImmuneTherapy (CCIT), Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1111/bcpt.12320DOI Listing
January 2015

Indoleamine 2,3-dioxygenase vaccination.

Oncoimmunology 2015 Jan 3;4(1):e983770. Epub 2015 Feb 3.

Department of Hematology; Center for Cancer Immune Therapy (CCIT); Copenhagen University Hospital ; Herlev, Denmark ; Department of Oncology; Copenhagen University Hospital ; Herlev, Denmark.

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http://dx.doi.org/10.4161/2162402X.2014.983770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368142PMC
January 2015

Successful treatment with Ipilimumab and Interleukin-2 in two patients with metastatic melanoma and systemic autoimmune disease.

Cancer Immunol Immunother 2014 Dec 17;63(12):1341-6. Epub 2014 Sep 17.

Department of Haematology and Oncology, Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-014-1607-yDOI Listing
December 2014

Spontaneous presence of FOXO3-specific T cells in cancer patients.

Oncoimmunology 2014;3(8):e953411. Epub 2014 Nov 14.

Center for Cancer Immune Therapy (CCIT); Department of Hematology; Copenhagen University Hospital ; Herlev ; Herlev, Denmark.

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http://dx.doi.org/10.4161/21624011.2014.953411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368145PMC
November 2014

Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?

Cancer Immunol Immunother 2014 Oct 7;63(10):1081-91. Epub 2014 Aug 7.

Department of Haematology and Department of Oncology, Herlev Hospital, Center for Cancer Immune Therapy (CCIT), University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark,

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http://dx.doi.org/10.1007/s00262-014-1580-5DOI Listing
October 2014

Simplified protocol for clinical-grade tumor-infiltrating lymphocyte manufacturing with use of the Wave bioreactor.

Cytotherapy 2014 Aug 13;16(8):1117-20. Epub 2014 May 13.

Center for Cancer Immune Therapy, Department of Hematology, Herlev, Denmark; Department of Oncology, Herlev Hospital, Herlev, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2014.02.004DOI Listing
August 2014

Late development of splenic sarcoidosis-like lesions in a patient with metastatic melanoma and long-lasting clinical response to ipilimumab.

Oncoimmunology 2014;3(8):e954506. Epub 2014 Aug 3.

Centre for Cancer Immune Therapy; Department of Haematology and Oncology; Herlev Hospital; University of Copenhagen ; Denmark ; Department of Oncology; Herlev Hospital; University of Copenhagen ; Denmark.

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http://dx.doi.org/10.4161/21624011.2014.954506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292567PMC
August 2014

Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase.

Clin Cancer Res 2014 Jan 11;20(1):221-32. Epub 2013 Nov 11.

Authors' Affiliations: Center for Cancer Immune Therapy, Department of Haematology & Department of Oncology, Copenhagen University Hospital at Herlev, Herlev; Department of Pathology, Bispebjerg Hospital, Team Bispebjerg (RH), Bispebjerg Bakke, Copenhagen NV, Denmark Interfaculty Institute of Biochemistry; and Department of Immunology, Interfaculty Institute of Cell Biology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1560DOI Listing
January 2014

In-chip fabrication of free-form 3D constructs for directed cell migration analysis.

Lab Chip 2013 Dec;13(24):4800-9

Department of Micro- and Nanotechnology, DTU Nanotech, Technical University of Denmark, Ørsteds Plads 345E, DK-2800 Kgs. Lyngby, Denmark.

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http://dx.doi.org/10.1039/c3lc50930cDOI Listing
December 2013

Analysis of survivin-specific T cells in breast cancer patients using human DCs engineered with survivin mRNA.

Methods Mol Biol 2013 ;969:275-92

Department of Hematology, Center for Cancer Immune Therapy (CCIT), University Hospital Herlev, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/978-1-62703-260-5_17DOI Listing
June 2013

Silencing of the glucocorticoid-induced leucine zipper improves the immunogenicity of clinical-grade dendritic cells.

Cytotherapy 2013 Jun;15(6):740-9

Center for Cancer Immune Therapy (CCIT), University Hospital Herlev, Copenhagen, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S14653249130038
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http://dx.doi.org/10.1016/j.jcyt.2013.02.005DOI Listing
June 2013

The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4 T cells.

Oncoimmunology 2013 Apr;2(4):e23991

1Center for Cancer Immune Therapy (CCIT); Department of Hematology and Oncology; Copenhagen University Hospital; Herlev, Denmark.

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http://dx.doi.org/10.4161/onci.23991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654604PMC
April 2013

HLA-restricted CTL that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients.

Cancer Res 2013 Mar 17;73(6):1764-76. Epub 2013 Jan 17.

Center for Cancer Immune Therapy, Department of Hematology and Oncology, Copenhagen University Hospital, Herlev, Herlev Ringvej, Herlev, Denmark.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3507DOI Listing
March 2013

Methods to improve adoptive T-cell therapy for melanoma: IFN-γ enhances anticancer responses of cell products for infusion.

J Invest Dermatol 2013 Feb 27;133(2):545-52. Epub 2012 Sep 27.

Department of Haematology, Center for Cancer Immune Therapy, Copenhagen University Hospital at Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1038/jid.2012.336DOI Listing
February 2013

Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients.

Oncoimmunology 2013 Feb;2(2):e23288

Department of Haematology and Oncology; Center for Cancer Immune Therapy (CCIT); Copenhagen University Hospital at Herlev; Herlev, Denmark.

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http://dx.doi.org/10.4161/onci.23288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601183PMC
February 2013

FDG PET scans as evaluation of clinical response to dendritic cell vaccination in patients with malignant melanoma.

Cancer Immunol Immunother 2013 Jan 22;62(1):17-25. Epub 2012 Jun 22.

Department of Haematology, Center for Cancer ImmuneTherapy (CCIT), University Hospital Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-012-1306-5DOI Listing
January 2013

Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy.

Vaccine 2013 Jan 29;31(4):639-46. Epub 2012 Nov 29.

Center for Cancer Immune Therapy, Department of Haematology, Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1016/j.vaccine.2012.11.053DOI Listing
January 2013

BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer.

Oncoimmunology 2012 Dec;1(9):1476-1483

Center for Cancer Immune Therapy; Department of Haematology; Copenhagen University Hospital at Herlev; Herlev, Denmark ; Department of Biomedical Sciences; University of Catania; Catania, Italy.

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http://dx.doi.org/10.4161/onci.21940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525603PMC
December 2012

Characterization of T-cell responses against IκBα in cancer patients.

Oncoimmunology 2012 Nov;1(8):1290-1296

Center for Cancer Immune Therapy (CCIT); Department of Hematology and Oncology; Copenhagen University Hospital; Herlev, Denmark.

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http://dx.doi.org/10.4161/onci.21625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518501PMC
November 2012

Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes.

Oncoimmunology 2012 Nov;1(8):1297-1304

Center for Cancer Immune Therapy; Department of Haematology; Copenhagen University Hospital at Herlev; Herlev, Denmark ; Department of Biomedical Sciences; University of Catania; Catania, Italy.

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http://dx.doi.org/10.4161/onci.21659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518502PMC
November 2012

Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial.

Cancer Immunol Immunother 2012 Oct 20;61(10):1791-804. Epub 2012 Mar 20.

Department of Haematology, Center for Cancer Immune Therapy, Copenhagen University Hospital, Herlev, Herlev Ringvej 75, 2730 Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-012-1242-4DOI Listing
October 2012

Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.

PLoS One 2012 23;7(4):e34568. Epub 2012 Apr 23.

Department of Hematology and Oncology, Center for Cancer Immune Therapy, Copenhagen University Hospital, Herlev, Herlev, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034568PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335144PMC
September 2012

Generation of autologous tumor-specific T cells for adoptive transfer based on vaccination, in vitro restimulation and CD3/CD28 dynabead-induced T cell expansion.

Cancer Immunol Immunother 2012 Aug 12;61(8):1221-31. Epub 2012 Jan 12.

Department of Hematology 54P4, Center for Cancer Immune Therapy, University Hospital Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1007/s00262-011-1199-8DOI Listing
August 2012

Effector and regulatory T cells in patients with acute optic neuritis.

Neuroimmunomodulation 2012 11;19(2):111-20. Epub 2012 Jan 11.

Department of Neurology, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark.

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http://dx.doi.org/10.1159/000330242DOI Listing
July 2012

Dissection of T-cell antigen specificity in human melanoma.

Cancer Res 2012 Apr 6;72(7):1642-50. Epub 2012 Feb 6.

Department of Hematology, Center for Cancer Immune Therapy and Oncology, University Hospital Herlev, Herlev, Denmark.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2614DOI Listing
April 2012