Ines de Santiago

Ines de Santiago

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Ines de Santiago

Ines de Santiago

Publications by authors named "Ines de Santiago"

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Immunophenotypes of pancreatic ductal adenocarcinoma: Meta-analysis of transcriptional subtypes.

Int J Cancer 2019 Aug 18;145(4):1125-1137. Epub 2019 Mar 18.

Department of Oncology, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/ijc.32186DOI Listing
August 2019

Analysis of ChIP-seq Data in R/Bioconductor.

Methods Mol Biol 2018 ;1689:195-226

Medical Research Council, London Institute of Medical Sciences, Imperial College London, London, UK.

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http://dx.doi.org/10.1007/978-1-4939-7380-4_17DOI Listing
May 2018

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

Authors:
Maya Ghoussaini Stacey L Edwards Kyriaki Michailidou Silje Nord Richard Cowper-Sal Lari Kinjal Desai Siddhartha Kar Kristine M Hillman Susanne Kaufmann Dylan M Glubb Jonathan Beesley Joe Dennis Manjeet K Bolla Qin Wang Ed Dicks Qi Guo Marjanka K Schmidt Mitul Shah Robert Luben Judith Brown Kamila Czene Hatef Darabi Mikael Eriksson Daniel Klevebring Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Bernard Thienpont Patrick Neven Hans Wildiers Annegien Broeks Laura J Van't Veer Emiel J Th Rutgers Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel Dos-Santos-Silva Lorna Gibson Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Per Hall Jingmei Li Jianjun Liu Keith Humphreys Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Keitaro Matsuo Hidemi Ito Hiroji Iwata Yasushi Yatabe Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Xiao-Ou Shu Wei Lu Yu-Tang Gao Qiuyin Cai Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Annika Lindblom Sara Margolin Soo Hwang Teo Cheng Har Yip Daphne S C Lee Tien Y Wong Maartje J Hooning John W M Martens J Margriet Collée Carolien H M van Deurzen John L Hopper Melissa C Southey Helen Tsimiklis Miroslav K Kapuscinski Chen-Yang Shen Pei-Ei Wu Jyh-Cherng Yu Shou-Tung Chen Grethe Grenaker Alnæs Anne-Lise Borresen-Dale Graham G Giles Roger L Milne Catriona McLean Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Mikael Hartman Hui Miao Shaik Ahmad Bin Syed Buhari Yik Ying Teo Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Hiltrud Brauch Thomas Brüning Yon-Dschun Koto Paolo Radice Paolo Peterlongo Bernardo Bonanni Sara Volorio Thilo Dörk Natalia V Bogdanova Sonja Helbig Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Ute Hamann Diana Torres Wei Zheng Jirong Long Hoda Anton-Culver Susan L Neuhausen Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Ines de Santiago Jason Carroll Carlos Caldas Melissa A Brown Mathieu Lupien Vessela N Kristensen Paul D P Pharoah Georgia Chenevix-Trench Juliet D French Douglas F Easton Alison M Dunning

Nat Commun 2018 04 10;9:16193. Epub 2018 Apr 10.

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http://dx.doi.org/10.1038/ncomms16193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898457PMC
April 2018

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells.

Nat Struct Mol Biol 2017 Jun 24;24(6):515-524. Epub 2017 Apr 24.

Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max Delbrück Centre for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.1038/nsmb.3402DOI Listing
June 2017

Complex multi-enhancer contacts captured by genome architecture mapping.

Nature 2017 03 8;543(7646):519-524. Epub 2017 Mar 8.

Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max-Delbrück Centre for Molecular Medicine, Robert-Rössle Straße, Berlin-Buch 13125, Germany.

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http://dx.doi.org/10.1038/nature21411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366070PMC
March 2017

BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes.

Genome Biol 2017 02 24;18(1):39. Epub 2017 Feb 24.

Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, UK.

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http://dx.doi.org/10.1186/s13059-017-1165-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326502PMC
February 2017

Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis.

PLoS Med 2017 01 31;14(1):e1002223. Epub 2017 Jan 31.

Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283690PMC
January 2017

FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness.

Carcinogenesis 2016 08 28;37(8):741-750. Epub 2016 May 28.

Present address: Abcam, Cambridge Science Park, Milton, Cambridge CB4 0FL, UK.

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http://dx.doi.org/10.1093/carcin/bgw065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967216PMC
August 2016

Regulators of genetic risk of breast cancer identified by integrative network analysis.

Nat Genet 2016 Jan 30;48(1):12-21. Epub 2015 Nov 30.

Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697365PMC
January 2016

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

Authors:
Maya Ghoussaini Stacey L Edwards Kyriaki Michailidou Silje Nord Richard Cowper-Sal Lari Kinjal Desai Siddhartha Kar Kristine M Hillman Susanne Kaufmann Dylan M Glubb Jonathan Beesley Joe Dennis Manjeet K Bolla Qin Wang Ed Dicks Qi Guo Marjanka K Schmidt Mitul Shah Robert Luben Judith Brown Kamila Czene Hatef Darabi Mikael Eriksson Daniel Klevebring Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Bernard Thienpont Patrick Neven Hans Wildiers Annegien Broeks Laura J Van't Veer Emiel J Th Rutgers Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel Dos-Santos-Silva Lorna Gibson Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Per Hall Jingmei Li Jianjun Liu Keith Humphreys Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Keitaro Matsuo Hidemi Ito Hiroji Iwata Yasushi Yatabe Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Xiao-Ou Shu Wei Lu Yu-Tang Gao Qiuyin Cai Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Annika Lindblom Sara Margolin Soo Hwang Teo Cheng Har Yip Daphne S C Lee Tien Y Wong Maartje J Hooning John W M Martens J Margriet Collée Carolien H M van Deurzen John L Hopper Melissa C Southey Helen Tsimiklis Miroslav K Kapuscinski Chen-Yang Shen Pei-Ei Wu Jyh-Cherng Yu Shou-Tung Chen Grethe Grenaker Alnæs Anne-Lise Borresen-Dale Graham G Giles Roger L Milne Catriona McLean Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Mikael Hartman Hui Miao Shaik Ahmad Bin Syed Buhari Yik Ying Teo Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Hiltrud Brauch Thomas Brüning Yon-Dschun Koto Paolo Radice Paolo Peterlongo Bernardo Bonanni Sara Volorio Thilo Dörk Natalia V Bogdanova Sonja Helbig Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Ute Hamann Diana Torres Wei Zheng Jirong Long Hoda Anton-Culver Susan L Neuhausen Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Alvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Ines de Santiago Jason Carroll Carlos Caldas Melissa A Brown Mathieu Lupien Vessela N Kristensen Paul D P Pharoah Georgia Chenevix-Trench Juliet D French Douglas F Easton Alison M Dunning

Nat Commun 2014 Sep 23;4:4999. Epub 2014 Sep 23.

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1038/ncomms5999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321900PMC
September 2014

Master regulators of FGFR2 signalling and breast cancer risk.

Nat Commun 2013 ;4:2464

1] Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK [2] Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK [3] [4].

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http://dx.doi.org/10.1038/ncomms3464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778544PMC
April 2014

Impact of artifact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data.

Front Genet 2014 10;5:75. Epub 2014 Apr 10.

Cambridge Institute CRUK, University of Cambridge Cambridge, UK.

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http://dx.doi.org/10.3389/fgene.2014.00075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989762PMC
April 2014

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

Authors:
Kerstin B Meyer Martin O'Reilly Kyriaki Michailidou Saskia Carlebur Stacey L Edwards Juliet D French Radhika Prathalingham Joe Dennis Manjeet K Bolla Qin Wang Ines de Santiago John L Hopper Helen Tsimiklis Carmel Apicella Melissa C Southey Marjanka K Schmidt Annegien Broeks Laura J Van 't Veer Frans B Hogervorst Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Peter A Fasching Michael P Lux Arif B Ekici Matthias W Beckmann Julian Peto Isabel Dos Santos Silva Olivia Fletcher Nichola Johnson Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Federick Marme Andreas Schneeweiss Christof Sohn Barbara Burwinkel Pascal Guénel Thérèse Truong Pierre Laurent-Puig Florence Menegaux Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Roger L Milne M Pilar Zamora Jose I Arias Javier Benitez Susan Neuhausen Hoda Anton-Culver Argyrios Ziogas Christina C Dur Hermann Brenner Heiko Müller Volker Arndt Christa Stegmaier Alfons Meindl Rita K Schmutzler Christoph Engel Nina Ditsch Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Keitaro Matsuo Hidemi Ito Hiroji Iwata Yasushi Yatabe Thilo Dörk Sonja Helbig Natalia V Bogdanova Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Georgia Chenevix-Trench Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Diether Lambrechts Bernard Thienpont Marie-Rose Christiaens Ann Smeets Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Bernardo Bonanni Loris Bernard Fergus J Couch Janet E Olson Xianshu Wang Kristen Purrington Graham G Giles Gianluca Severi Laura Baglietto Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Soo-Hwang Teo Cheng-Har Yip Sze-Yee Phuah Vessela Kristensen Grethe Grenaker Alnæs Anne-Lise Børresen-Dale Wei Zheng Sandra Deming-Halverson Martha Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robert A E M Tollenaar Caroline M Seynaeve Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Hartef Darabi Kimael Eriksson Maartje J Hooning John W M Martens Ans M W van den Ouweland Carolien H M van Deurzen Per Hall Jingmei Li Jianjun Liu Keith Humphreys Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Angela Cox Malcolm W R Reed William Blot Lisa B Signorello Qiuyin Cai Paul D P Pharoah Maya Ghoussaini Patricia Harrington Jonathan Tyrer Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Mikael Hartman Miao Hui Wei-Yen Lim Shaik A Buhari Ute Hamann Asta Försti Thomas Rüdiger Hans-Ulrich Ulmer Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Celine Vachon Susan Slager Florentia Fostira Robert Pilarski Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Ming-Feng Hou Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Bruce A J Ponder Alison M Dunning Douglas F Easton

Am J Hum Genet 2013 Dec 27;93(6):1046-60. Epub 2013 Nov 27.

CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2013.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852923PMC
December 2013

Eukaryotic gene regulation in three dimensions and its impact on genome evolution.

Curr Opin Genet Dev 2008 Dec 27;18(6):571-82. Epub 2008 Nov 27.

MRC Laboratory of Molecular Biology, Cambridge, UK.

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http://dx.doi.org/10.1016/j.gde.2008.10.002DOI Listing
December 2008