Publications by authors named "Ines Baldeiras"

62Publications

C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia.

Exp Gerontol 2020 Sep 16;138:111004. Epub 2020 Jun 16.

Neurology Department, Centro Hospitalar e Universitário de Coimbra, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal; Faculty of Medicine, University of Coimbra, R. Larga, 3004-504 Coimbra, Portugal; Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.exger.2020.111004DOI Listing
September 2020

Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease Patients.

Biomolecules 2019 11 28;9(12). Epub 2019 Nov 28.

Department of Neurology, National Reference Center for CJD Surveillance University Medical Center Göttingen, 37075 Göttingen, Germany.

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http://dx.doi.org/10.3390/biom9120800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995564PMC
November 2019

Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer's disease.

Alzheimers Res Ther 2019 11 23;11(1):91. Epub 2019 Nov 23.

Laboratory of Neurochemistry, Neurology Department, Centro Hospitalar e Universitário de Coimbra, 3000-075, Coimbra, Portugal.

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http://dx.doi.org/10.1186/s13195-019-0550-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875031PMC
November 2019

Lower CSF Amyloid-Beta Predicts a Higher Mortality Rate in Frontotemporal Dementia.

Diagnostics (Basel) 2019 Oct 25;9(4). Epub 2019 Oct 25.

Neurology Department, Centro Hospitalar e Universitário de Coimbra, 3000-045 Coimbra, Portugal.

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http://dx.doi.org/10.3390/diagnostics9040162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963225PMC
October 2019

Increased CSF tau is associated with a higher risk of seizures in patients with Alzheimer's disease.

Epilepsy Behav 2019 09 2;98(Pt A):207-209. Epub 2019 Aug 2.

Neurology Department, Centro Hospitalário e Universitário de Coimbra, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal; Faculty of Medicine, University of Coimbra, R. Larga, 3004-504 Coimbra, Portugal; Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.yebeh.2019.06.033DOI Listing
September 2019

Erlangen Score as a tool to predict progression from mild cognitive impairment to dementia in Alzheimer's disease.

Alzheimers Res Ther 2019 01 5;11(1). Epub 2019 Jan 5.

Department of Neurodegeneration Diagnostics, Medical University of Białystok, Białystok, Poland.

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http://dx.doi.org/10.1186/s13195-018-0456-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320577PMC
January 2019

The Head Turning Sign in Dementia and Mild Cognitive Impairment: Its Relationship to Cognition, Behavior, and Cerebrospinal Fluid Biomarkers.

Dement Geriatr Cogn Disord 2018 9;46(1-2):42-49. Epub 2018 Aug 9.

Neurology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1159/000486531DOI Listing
November 2018

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Authors:
Niklas Mattsson Colin Groot Willemijn J Jansen Susan M Landau Victor L Villemagne Sebastiaan Engelborghs Mark M Mintun Alberto Lleo José Luis Molinuevo William J Jagust Giovanni B Frisoni Adrian Ivanoiu Gaël Chételat Catarina Resende de Oliveira Karen M Rodrigue Johannes Kornhuber Anders Wallin Aleksandra Klimkowicz-Mrowiec Ramesh Kandimalla Julius Popp Pauline P Aalten Dag Aarsland Daniel Alcolea Ina S Almdahl Inês Baldeiras Mark A van Buchem Enrica Cavedo Kewei Chen Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Kiran Dip Gill Olymbia Gkatzima Timo Grimmer Harald Hampel Sanna-Kaisa Herukka Peter Johannsen Koen van Laere Mony J de Leon Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Barbara Mroczko Arto Nordlund Sudesh Prabhakar Oliver Peters Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Frans R J Verhey Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Rik Vandenberghe David J Brooks Tormod Fladby Christopher C Rowe Alexander Drzezga Marcel M Verbeek Marie Sarazin David A Wolk Adam S Fleisher William E Klunk Duk L Na Pascual Sánchez-Juan Dong Young Lee Agneta Nordberg Magda Tsolaki Vincent Camus Juha O Rinne Anne M Fagan Henrik Zetterberg Kaj Blennow Gil D Rabinovici Oskar Hansson Bart N M van Berckel Wiesje M van der Flier Philip Scheltens Pieter Jelle Visser Rik Ossenkoppele

Alzheimers Dement 2018 07 28;14(7):913-924. Epub 2018 Mar 28.

Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.02.009DOI Listing
July 2018

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Authors:
Willemijn J Jansen Rik Ossenkoppele Betty M Tijms Anne M Fagan Oskar Hansson William E Klunk Wiesje M van der Flier Victor L Villemagne Giovanni B Frisoni Adam S Fleisher Alberto Lleó Mark A Mintun Anders Wallin Sebastiaan Engelborghs Duk L Na Gäel Chételat José Luis Molinuevo Susan M Landau Niklas Mattsson Johannes Kornhuber Osama Sabri Christopher C Rowe Lucilla Parnetti Julius Popp Tormod Fladby William J Jagust Pauline Aalten Dong Young Lee Rik Vandenberghe Catarina Resende de Oliveira Elisabeth Kapaki Lutz Froelich Adrian Ivanoiu Tomasz Gabryelewicz Marcel M Verbeek Páscual Sanchez-Juan Helmut Hildebrandt Vincent Camus Marzena Zboch David J Brooks Alexander Drzezga Juha O Rinne Andrew Newberg Alexandre de Mendonça Marie Sarazin Gil D Rabinovici Karine Madsen Milica G Kramberger Agneta Nordberg Vincent Mok Barbara Mroczko David A Wolk Philipp T Meyer Magda Tsolaki Philip Scheltens Frans R J Verhey Pieter Jelle Visser Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kaj Blennow Mark A van Buchem Enrica Cavedo Kewei Chen Elena Chipi Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Olymbia Gkatzima Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Peter Johannsen Aleksandra Klimkowicz-Mrowiec Sebastian Köhler Norman Koglin Koen van Laere Mony de Leon Viviana Lisetti Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Arto Nordlund Gerald P Novak George P Paraskevas Gayan Perera Oliver Peters Inez H G B Ramakers Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Henrik Zetterberg

JAMA Psychiatry 2018 01;75(1):84-95

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1001/jamapsychiatry.2017.3391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786156PMC
January 2018

Development of a Mitochondriotropic Antioxidant Based on Caffeic Acid: Proof of Concept on Cellular and Mitochondrial Oxidative Stress Models.

J Med Chem 2017 08 10;60(16):7084-7098. Epub 2017 Aug 10.

CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto , Porto 4169-007, Portugal.

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http://dx.doi.org/10.1021/acs.jmedchem.7b00741DOI Listing
August 2017

Association between butyrylcholinesterase and cerebrospinal fluid biomarkers in Alzheimer's disease patients.

Neurosci Lett 2017 02 17;641:101-106. Epub 2017 Jan 17.

Laboratory of Neurochemistry, Coimbra University Hospital, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.neulet.2017.01.036DOI Listing
February 2017

Multiple sclerosis: Association of gelatinase B/matrix metalloproteinase-9 with risk and clinical course the disease.

Mult Scler Relat Disord 2017 Jan 13;11:71-76. Epub 2016 Dec 13.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Largo Marquês de Pombal, 3004-517 Coimbra, Portugal; Laboratory of Neurochemistry, Centro Hospitalar e Universitário de Coimbra (CHUC), Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.msard.2016.12.003DOI Listing
January 2017

Portuguese family with the co-occurrence of frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis phenotypes due to progranulin gene mutation.

Neurobiol Aging 2016 May 3;41:200.e1-200.e5. Epub 2016 Mar 3.

Neurology Department, Coimbra University Hospital, Coimbra, Portugal; Neurology Department, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.02.019DOI Listing
May 2016

Cerebrospinal fluid Aβ40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease.

J Neurol Sci 2015 Nov 10;358(1-2):308-16. Epub 2015 Sep 10.

Laboratory of Neurochemistry, Coimbra University Hospital, Portugal; Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.jns.2015.09.022DOI Listing
November 2015

Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-AD Biomarkers.

Front Neurol 2015 8;6:153. Epub 2015 Jul 8.

Center for Neuroscience and Cell Biology (CNC), University of Coimbra , Coimbra , Portugal ; Neurochemistry Laboratory, Neurology Department, Coimbra University Hospital , Coimbra , Portugal ; Faculty of Medicine, University of Coimbra , Coimbra , Portugal.

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http://dx.doi.org/10.3389/fneur.2015.00153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495343PMC
July 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Authors:
Willemijn J Jansen Rik Ossenkoppele Dirk L Knol Betty M Tijms Philip Scheltens Frans R J Verhey Pieter Jelle Visser Pauline Aalten Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kristen Bibeau Kaj Blennow David J Brooks Mark A van Buchem Vincent Camus Enrica Cavedo Kewei Chen Gael Chetelat Ann D Cohen Alexander Drzezga Sebastiaan Engelborghs Anne M Fagan Tormod Fladby Adam S Fleisher Wiesje M van der Flier Lisa Ford Stefan Förster Juan Fortea Nadia Foskett Kristian S Frederiksen Yvonne Freund-Levi Giovanni B Frisoni Lutz Froelich Tomasz Gabryelewicz Kiran Dip Gill Olymbia Gkatzima Estrella Gómez-Tortosa Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Helmut Hildebrandt Lianna Ishihara Adrian Ivanoiu William J Jagust Peter Johannsen Ramesh Kandimalla Elisabeth Kapaki Aleksandra Klimkowicz-Mrowiec William E Klunk Sebastian Köhler Norman Koglin Johannes Kornhuber Milica G Kramberger Koen Van Laere Susan M Landau Dong Young Lee Mony de Leon Viviana Lisetti Alberto Lleó Karine Madsen Wolfgang Maier Jan Marcusson Niklas Mattsson Alexandre de Mendonça Olga Meulenbroek Philipp T Meyer Mark A Mintun Vincent Mok José Luis Molinuevo Hanne M Møllergård John C Morris Barbara Mroczko Stefan Van der Mussele Duk L Na Andrew Newberg Agneta Nordberg Arto Nordlund Gerald P Novak George P Paraskevas Lucilla Parnetti Gayan Perera Oliver Peters Julius Popp Sudesh Prabhakar Gil D Rabinovici Inez H G B Ramakers Lorena Rami Catarina Resende de Oliveira Juha O Rinne Karen M Rodrigue Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Christopher C Rowe Eckart Rüther Osama Sabri Páscual Sanchez-Juan Isabel Santana Marie Sarazin Johannes Schröder Christin Schütte Sang W Seo Femke Soetewey Hilkka Soininen Luiza Spiru Hanne Struyfs Charlotte E Teunissen Magda Tsolaki Rik Vandenberghe Marcel M Verbeek Victor L Villemagne Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Anders Wallin Åsa K Wallin Jens Wiltfang David A Wolk Marzena Zboch Henrik Zetterberg

JAMA 2015 May;313(19):1924-38

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden87UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jama.2015.4668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486209PMC
May 2015

Validation of 14-3-3 Protein as a Marker in Sporadic Creutzfeldt-Jakob Disease Diagnostic.

Mol Neurobiol 2016 May 7;53(4):2189-99. Epub 2015 May 7.

Department of Neurology, University Medical Center Göttingen and German Center for Neurodegenerative Diseases (DZNE)-site Göttingen, Robert-Koch Str. 40, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1007/s12035-015-9167-5DOI Listing
May 2016

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease.

Biochim Biophys Acta 2015 Jul 6;1852(7):1428-41. Epub 2015 Apr 6.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2015.03.015DOI Listing
July 2015

Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes.

Curr Neurovasc Res 2014 ;11(4):330-9

Center for Neuroscience and Cell Biology, University of Coimbra 3004-504 & Laboratory of Physiology - Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.

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http://dx.doi.org/10.2174/1567202611666140903122801DOI Listing
July 2015

Rapeseed oil-rich diet alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics.

Arch Toxicol 2013 Dec 1;87(12):2151-63. Epub 2013 May 1.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Largo Marquês de Pombal, 3004-517, Coimbra, Portugal.

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http://dx.doi.org/10.1007/s00204-013-1068-7DOI Listing
December 2013

[Bilateral hyperintensity of the pulvinar and dorsomedial nucleus of the thalamus in sporadic Creutzfeldt-Jakob disease].

Acta Med Port 2012 2;25 Suppl 1:41-4. Epub 2012 Nov 2.

Serviço de Imagiologia, Hospitais da Universidade de Coimbra, Coimbra, Portugal.

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December 2013

Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance.

Neurobiol Dis 2013 Jan 24;49:1-12. Epub 2012 Aug 24.

Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; Institute of Physiology, Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2012.08.008DOI Listing
January 2013

Differentiation-dependent doxorubicin toxicity on H9c2 cardiomyoblasts.

Cardiovasc Toxicol 2012 Dec;12(4):326-40

CNC, Center for Neuroscience and Cell Biology, Largo Marques de Pombal, University of Coimbra, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1007/s12012-012-9177-8DOI Listing
December 2012

Transthyretin decrease in plasma of MCI and AD patients: investigation of mechanisms for disease modulation.

Curr Alzheimer Res 2012 Oct;9(8):881-9

Molecular Neurobiology Unit, IBMC- Instituto de Biologia Molecular e Celular, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.2174/156720512803251057DOI Listing
October 2012

Oxidative stress adaptation in aggressive prostate cancer may be counteracted by the reduction of glutathione reductase.

FEBS Open Bio 2012 30;2:119-28. Epub 2012 May 30.

General Pathology Laboratory, Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal ; CIMAGO - Centre of Investigation in Environment, Genetics and Oncobiology, Faculty of Medicine, University of Coimbra, Apartado, 9015 3001-301 Coimbra, Portugal ; CNC - Centre of Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.fob.2012.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642126PMC
May 2013

Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lung.

Chem Biol Interact 2010 Dec 7;188(3):478-86. Epub 2010 Oct 7.

Department of Life Sciences, University of Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.cbi.2010.09.027DOI Listing
December 2010

Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes.

Curr Neurovasc Res 2010 Nov;7(4):288-300

Center for Neuroscience and Cell Biology, Faculty of Sciences and Technology, University of Coimbra, 3000-354 Coimbra, Portugal.

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http://dx.doi.org/10.2174/156720210793180765DOI Listing
November 2010

Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment.

J Alzheimers Dis 2010 ;21(4):1165-77

Laboratory of Neurochemistry, Neurology Department, Coimbra University Hospital, Coimbra, Portugal.

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http://dx.doi.org/10.3233/jad-2010-091723DOI Listing
January 2012

Diagnostic value of CSF protein profile in a Portuguese population of sCJD patients.

J Neurol 2009 Sep 6;256(9):1540-50. Epub 2009 May 6.

Neurology Department, Laboratory of Neurochemistry, Coimbra University Hospital, Praceta Mota Pinto, 3000 Coimbra, Portugal.

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http://link.springer.com/content/pdf/10.1007/s00415-009-5160
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http://link.springer.com/10.1007/s00415-009-5160-0
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http://dx.doi.org/10.1007/s00415-009-5160-0DOI Listing
September 2009

Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet.

Scand J Gastroenterol 2008 Jan;43(1):95-102

Unidade de Nutrição e Metabolismo, Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Portugal.

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http://dx.doi.org/10.1080/00365520701559003DOI Listing
January 2008

Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease.

J Alzheimers Dis 2008 Sep;15(1):117-28

Laboratory of Neurochemistry, Neurology Department, Coimbra University Hospital, Coimbra, Portugal.

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http://dx.doi.org/10.3233/jad-2008-15110DOI Listing
September 2008

Protein kinase C isoform specificity of cholinergic potentiation of glucose-induced pulsatile 5-HT/ insulin release from mouse pancreatic islets.

Biol Res 2006 7;39(3):531-9. Epub 2006 Nov 7.

Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.4067/s0716-97602006000300014DOI Listing
May 2007