Ina Poser

Ina Poser

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Ina Poser

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Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin.

EMBO J 2019 08 4;38(15):e101341. Epub 2019 Jul 4.

Centre for Neuroscience and Nanotechnology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.

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http://dx.doi.org/10.15252/embj.2018101341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669919PMC
August 2019

Publisher Correction: Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency.

Nat Cell Biol 2019 Jul;21(7):911-912

Department of Molecular Biology, Faculty of Science, Radboud University, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1038/s41556-019-0341-2DOI Listing
July 2019

Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency.

Nat Cell Biol 2019 05 29;21(5):568-578. Epub 2019 Apr 29.

Department of Molecular Biology, Faculty of Science, Radboud University, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.

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http://www.nature.com/articles/s41556-019-0310-9
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http://dx.doi.org/10.1038/s41556-019-0310-9DOI Listing
May 2019

Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding.

Nat Commun 2017 11 2;8(1):1266. Epub 2017 Nov 2.

Department of Biosystems Science and Engineering (D-BSSE), Eidgenössische Technische Hochschule (ETH) Zurich, Mattenstrasse 26, 4058, Basel, Switzerland.

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http://dx.doi.org/10.1038/s41467-017-01147-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668354PMC
November 2017

Cellular differentiation state modulates the mRNA export activity of SR proteins.

J Cell Biol 2017 07 7;216(7):1993-2009. Epub 2017 Jun 7.

Cluster of Excellence Macromolecular Complexes, Institute of Cell Biology and Neuroscience, Goethe University Frankfurt, Frankfurt am Main, Germany

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http://dx.doi.org/10.1083/jcb.201610051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496613PMC
July 2017

Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins.

J Proteome Res 2017 01 26;16(1):147-155. Epub 2016 Oct 26.

Science for Life Laboratory, Royal Institute of Technology , SE-114 28 Stockholm, Sweden.

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http://dx.doi.org/10.1021/acs.jproteome.6b00821DOI Listing
January 2017

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

J Cell Biol 2016 Nov 8;215(4):543-558. Epub 2016 Nov 8.

Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany

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http://dx.doi.org/10.1083/jcb.201601090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119934PMC
November 2016

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

Mol Cell 2016 09 25;63(5):796-810. Epub 2016 Aug 25.

Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41125, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.07.021DOI Listing
September 2016

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.

Nature 2016 07 29;535(7611):308-12. Epub 2016 Jun 29.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.

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http://dx.doi.org/10.1038/nature18610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947524PMC
July 2016

PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.

J Biol Chem 2016 May 4;291(21):11016-29. Epub 2016 Apr 4.

From the Department of Cell Biology and Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211-4 Geneva, Switzerland,

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http://dx.doi.org/10.1074/jbc.M115.712935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900252PMC
May 2016

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

J Biol Chem 2016 Apr 3;291(14):7313-24. Epub 2016 Feb 3.

From the Department of Molecular Cancer Research, University Medical Center Utrecht, Universiteitsweg 100, 3584CG Utrecht, The Netherlands, Department of Molecular Biology, Radboud Institute for Molecular Life Sciences, Geert Grooteplein Zuid 30, 6525GA Nijmegen, The Netherlands,

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http://dx.doi.org/10.1074/jbc.M115.701227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817164PMC
April 2016

Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission.

Mol Biol Cell 2016 Mar 13;27(5):812-27. Epub 2016 Jan 13.

Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.

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http://dx.doi.org/10.1091/mbc.E15-02-0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803307PMC
March 2016

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Cell 2015 Oct 22;163(3):712-23. Epub 2015 Oct 22.

Max Planck Institute of Biochemistry, 82152 Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.09.053DOI Listing
October 2015

Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.

Cell Syst 2015 Aug 26;1(2):141-51. Epub 2015 Aug 26.

Medical Systems Biology, UCC, Medical Faculty Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2015.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023010PMC
August 2015

Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis.

EMBO J 2015 Jan 4;34(2):251-65. Epub 2014 Dec 4.

Proteomics Center at Children's Hospital Boston, Boston, MA, USA Department of Neurobiology, Harvard Medical School and Children's Hospital Boston, Boston, MA, USA.

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http://dx.doi.org/10.15252/embj.201385162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337065PMC
January 2015

MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain.

Proteomics 2014 Oct 24;14(19):2179-89. Epub 2014 Apr 24.

Molecular Cancer Research, Cancer Genomics, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/pmic.201400013DOI Listing
October 2014

Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis.

Proc Natl Acad Sci U S A 2014 Jan 2;111(3):E354-63. Epub 2014 Jan 2.

Ministry of Education Key Laboratory of Protein Sciences, Center for Structural Biology, School of Life Sciences, and Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, People's Republic of China.

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http://dx.doi.org/10.1073/pnas.1317535111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903230PMC
January 2014

The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.

Mol Biol Cell 2013 Nov 18;24(22):3557-68. Epub 2013 Sep 18.

Department of RNA Biology, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague 142 20, Czech Republic Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague 142 20, Czech Republic Max Planck Institute for Molecular Cell Biology and Genetics, Dresden 01307, Germany J. Heyrovsky Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Prague 182 23, Czech Republic.

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http://dx.doi.org/10.1091/mbc.E13-06-0303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826993PMC
November 2013

A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis.

Dev Cell 2013 Sep 5;26(5):496-510. Epub 2013 Sep 5.

Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA; Center for Integrated Protein Science CIPSM, Department Biology II, Ludwig-Maximilians University, Munich, 82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1016/j.devcel.2013.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239416PMC
September 2013

Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase.

J Cell Biol 2013 Aug;202(4):623-36

Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan.

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http://www.jcb.org/lookup/doi/10.1083/jcb.201302123
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http://dx.doi.org/10.1083/jcb.201302123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747305PMC
August 2013

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Cell 2013 Feb 8;152(4):909-22. Epub 2013 Feb 8.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research and Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94122, USA.

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http://dx.doi.org/10.1016/j.cell.2013.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652613PMC
February 2013

Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics.

Nucleic Acids Res 2013 Jan 12;41(1):e28. Epub 2012 Oct 12.

Department of Molecular Cancer Research, UMC Utrecht, Universiteitsweg 100, 3584CG Utrecht, The Netherlands.

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https://academic.oup.com/nar/article/41/1/e28/1177414
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http://dx.doi.org/10.1093/nar/gks941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592467PMC
January 2013

BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures.

Mol Biol Cell 2012 Nov 5;23(21):4226-41. Epub 2012 Sep 5.

Department of Cell Biology, Erasmus Medical Centre, 3000 CA Rotterdam, Netherlands Department of Neuroscience, Erasmus Medical Centre, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1091/mbc.E12-03-0210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484101PMC
November 2012

Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores.

J Cell Biol 2012 Jul 16;198(2):173-83. Epub 2012 Jul 16.

Institute of Biochemistry, Swiss Federal Institute of Technology Zurich, CH-8093 Zurich, Switzerland.

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http://www.jcb.org/lookup/doi/10.1083/jcb.201112112
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http://dx.doi.org/10.1083/jcb.201112112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410419PMC
July 2012

ARF6 GTPase protects the post-mitotic midbody from 14-3-3-mediated disintegration.

EMBO J 2012 May 11;31(11):2604-14. Epub 2012 May 11.

The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/emboj.2012.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365424PMC
May 2012

From RNAi screens to molecular function in embryonic stem cells.

Stem Cell Rev Rep 2012 Mar;8(1):32-42

University Hospital Carl Gustav Carus and Medical Faculty, University of Technology Dresden, Fetscherstr. 74, 01307, Dresden, Germany.

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http://dx.doi.org/10.1007/s12015-011-9269-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285751PMC
March 2012

Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments.

Science 2011 Mar 10;331(6024):1616-20. Epub 2011 Feb 10.

Institute of Biochemistry, Department of Biology, Swiss Federal Institute of Technology Zurich (ETHZ), Schafmattstrasse 18, Zurich, Switzerland.

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http://dx.doi.org/10.1126/science.1201847DOI Listing
March 2011

The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells.

J Cell Biol 2010 Oct;191(1):75-86

Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, 142 20 Prague, Czech Republic.

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http://dx.doi.org/10.1083/jcb.201004030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953428PMC
October 2010

CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.

Mol Biosyst 2010 Sep 4;6(9):1700-6. Epub 2010 Jun 4.

Department of Physiological Chemistry and Cancer Genomics Centre, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1039/c004108dDOI Listing
September 2010

Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions.

J Cell Biol 2010 May;189(4):739-54

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1083/jcb.200911091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872919PMC
May 2010

Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs.

Chromosoma 2010 Apr 11;119(2):149-65. Epub 2009 Nov 11.

Department of Cell Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152, Martinsried, Munich, Germany.

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http://dx.doi.org/10.1007/s00412-009-0244-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846388PMC
April 2010

SR protein family members display diverse activities in the formation of nascent and mature mRNPs in vivo.

Mol Cell 2009 Apr;34(2):179-90

Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, Dresden, Germany.

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http://dx.doi.org/10.1016/j.molcel.2009.02.031DOI Listing
April 2009

Loss of full length CtBP1 expression enhances the invasive potential of human melanoma.

BMC Cancer 2009 Feb 12;9:52. Epub 2009 Feb 12.

Institute of Pathology, University Regensburg, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1186/1471-2407-9-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650708PMC
February 2009

Tandem affinity purification of functional TAP-tagged proteins from human cells.

Nat Protoc 2007 ;2(5):1145-51

Department of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Dr Bohr-Gasse 1, 1030 Vienna, Austria.

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http://www.nature.com/doifinder/10.1038/nprot.2007.172
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http://dx.doi.org/10.1038/nprot.2007.172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957861PMC
January 2008

Genome-scale RNAi profiling of cell division in human tissue culture cells.

Nat Cell Biol 2007 Dec 11;9(12):1401-12. Epub 2007 Nov 11.

Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1038/ncb1659DOI Listing
December 2007

Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling.

Mol Cell Neurosci 2007 Apr 11;34(4):603-11. Epub 2007 Jan 11.

University of Regensburg Medical School, D-93053 Regensburg, Germany.

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http://dx.doi.org/10.1016/j.mcn.2007.01.002DOI Listing
April 2007

Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes.

J Cell Sci 2007 Apr 13;120(Pt 7):1245-55. Epub 2007 Mar 13.

Research Institute of Molecular Pathology, Dr Bohrgasse 7, A-1030 Vienna, Austria.

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http://dx.doi.org/10.1242/jcs.03425DOI Listing
April 2007

Snail-regulated genes in malignant melanoma.

Melanoma Res 2005 Aug;15(4):305-13

Institute of Pathology, University of Regensburg, D-93053 Regensburg, Germany.

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http://dx.doi.org/10.1097/00008390-200508000-00012DOI Listing
August 2005

Characterization of Sno expression in malignant melanoma.

Int J Oncol 2005 May;26(5):1411-7

University of Regensburg Medical School, D-93053 Regensburg, Germany.

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May 2005

Inhibition of melanoma inhibitory activity (MIA) expression in melanoma cells leads to molecular and phenotypic changes.

Pigment Cell Res 2005 Apr;18(2):92-101

Institute of Pathology, University of Regensburg, D-93053 Regensburg, Germany.

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http://doi.wiley.com/10.1111/j.1600-0749.2005.00212.x
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http://dx.doi.org/10.1111/j.1600-0749.2005.00212.xDOI Listing
April 2005

RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells.

Proc Natl Acad Sci U S A 2005 Feb 3;102(7):2396-401. Epub 2005 Feb 3.

Max Planck Institute for Molecular Cell Biology and Genetics, 01307 Dresden, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0409861102
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http://dx.doi.org/10.1073/pnas.0409861102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548992PMC
February 2005

Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration.

Cancer Res 2005 Jan;65(2):448-56

University of Regensburg Medical School, Regensburg, Germany.

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January 2005

Functional role of MIA in melanocytes and early development of melanoma.

Oncogene 2004 Aug;23(36):6115-24

Institute of Pathology, University of Regensburg, Franz-Josef-Strauss-Allee 11, D-93053 Regensburg, Germany.

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http://dx.doi.org/10.1038/sj.onc.1207797DOI Listing
August 2004

Ultraviolet radiation induces release of MIA: a new mechanism for UVR-induced progression of melanoma.

Int J Oncol 2004 Jul;25(1):105-11

Department of Dermatology, University of Colorado Health Sciences Center, Denver, CO 80262, USA.

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July 2004

Interphase fish analysis of cell cycle genes in asbestos-treated human mesothelial cells (HMC), SV40-transformed HMC (MeT-5A) and mesothelioma cells (COLO).

Cell Mol Biol (Noisy-le-grand) 2002 ;48 Online Pub:OL271-7

Institute of Hygiene and Occupational Health, University of Essen, Hufelandstrasse 55, 45147 Essen, Germany.

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September 2003

Down-regulation of COOH-terminal binding protein expression in malignant melanomas leads to induction of MIA expression.

Cancer Res 2002 Oct;62(20):5962-6

Institute of Pathology, RWTH Aachen, Germany.

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October 2002