In-Hyun Park

In-Hyun Park

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In-Hyun Park

Publications by authors named "In-Hyun Park"

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Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain.

Cell Rep 2020 Feb;30(6):1682-1689.e3

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.01.038DOI Listing
February 2020

The critical role of persistent sodium current in hippocampal gamma oscillations.

Neuropharmacology 2020 Jan 21;162:107787. Epub 2019 Sep 21.

Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA; Department of Neuroscience, University of Kentucky, Lexington, KY 40536, USA; Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2019.107787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952064PMC
January 2020

The RNA exosome nuclease complex regulates human embryonic stem cell differentiation.

J Cell Biol 2019 Aug 15;218(8):2564-2582. Epub 2019 Jul 15.

Department of Cell Biology, Yale School of Medicine, New Haven, CT

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http://dx.doi.org/10.1083/jcb.201811148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683745PMC
August 2019

hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids.

Cell Stem Cell 2019 03 21;24(3):487-497.e7. Epub 2019 Feb 21.

Department of Genetics, Yale Stem Cell Center, Yale Child Study Center, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853597PMC
March 2019

Generation and Fusion of Human Cortical and Medial Ganglionic Eminence Brain Organoids.

Curr Protoc Stem Cell Biol 2018 11 11;47(1). Epub 2018 Sep 11.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1002/cpsc.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402040PMC
November 2018

Correction to: New Advances in Human X Chromosome Status from a Developmental and Stem Cell Biology.

Tissue Eng Regen Med 2018 02 19;15(1):125. Epub 2018 Jan 19.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520 USA.

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http://dx.doi.org/10.1007/s13770-017-0111-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171639PMC
February 2018

New Advances in Human X chromosome status from a Developmental and Stem Cell Biology.

Tissue Eng Regen Med 2017 Dec 22;14(6):643-652. Epub 2017 Nov 22.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1007/s13770-017-0096-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738034PMC
December 2017

Enhanced Therapeutic and Long-Term Dynamic Vascularization Effects of Human Pluripotent Stem Cell-Derived Endothelial Cells Encapsulated in a Nanomatrix Gel.

Circulation 2017 Nov 29;136(20):1939-1954. Epub 2017 Sep 29.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA (S.-J.L., Y.-D.S., A.A., S.K., J.B., J.W.H., Y.-S.Y.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685906PMC
November 2017

Neural Stem Cells Restore Hair Growth Through Activation of the Hair Follicle Niche.

Cell Transplant 2016 22;25(8):1439-51. Epub 2016 Apr 22.

School of Biosystem and Biomedical Science, College of Health Science, Korea University, Anam-dong, Seongbuk-gu, Seoul, Republic of Korea.

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http://journals.sagepub.com/doi/full/10.3727/096368916X69146
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http://dx.doi.org/10.3727/096368916X691466DOI Listing
October 2017

Development of an inducible platform for intercellular protein delivery.

Int J Pharm 2017 Apr 28;522(1-2):1-10. Epub 2017 Feb 28.

Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112 Blindern, Oslo 0317, Norway; Norwegian Center for Stem Cell Research, PO Box 1112 Blindern, Oslo 0317, Norway; Institute of Immunology, Oslo University Hospital-Rikshospitalet, PO Box 4950 Nydalen, Oslo 0424, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2017.02.067DOI Listing
April 2017

Direct Reprogramming of Human Dermal Fibroblasts Into Endothelial Cells Using ER71/ETV2.

Circ Res 2017 Mar 21;120(5):848-861. Epub 2016 Dec 21.

From the Department of Pharmacology, College of Medicine, University of Illinois at Chicago (C.P., E.J.K.); Department of Pediatrics, Children's Heart Research and Outcomes Center, Emory University School of Medicine, Atlanta, GA (C.P., J.Y.K., S.Y.O.); Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA (S.L., J.W.H., K.C., S.K., H.J.A., C.M.S., S.S., Y.-s.Y.); Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT (Y.T., I.-H.P.); and Division of Cardiology, Department of Medicine, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea (S.-J.L., Y.-s.Y.)

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336520PMC
March 2017

Modeling and correction of structural variations in patient-derived iPSCs using CRISPR/Cas9.

Nat Protoc 2016 Nov 6;11(11):2154-2169. Epub 2016 Oct 6.

Department of Physiology, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/nprot.2016.129DOI Listing
November 2016

Dnmt1 regulates the myogenic lineage specification of muscle stem cells.

Sci Rep 2016 10 18;6:35355. Epub 2016 Oct 18.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, 10 Amistad, 201B, New Haven, CT, 06520.

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http://dx.doi.org/10.1038/srep35355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082760PMC
October 2016

Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family.

Stem Cell Reports 2016 07 30;7(1):43-54. Epub 2016 Jun 30.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, 10 Amistad, 201B, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945581PMC
July 2016

Ethanol upregulates NMDA receptor subunit gene expression in human embryonic stem cell-derived cortical neurons.

PLoS One 2015 12;10(8):e0134907. Epub 2015 Aug 12.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States of America; VA Medical Center, VA Connecticut Healthcare System, West Haven, CT, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134907PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534442PMC
May 2016

Histone Deacetylases Positively Regulate Transcription through the Elongation Machinery.

Cell Rep 2015 Nov 5;13(7):1444-1455. Epub 2015 Nov 5.

Department of Biological Sciences and Center for Systems Biology, The University of Texas at Dallas, Richardson, TX 75080, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934896PMC
November 2015

Tgif1 Counterbalances the Activity of Core Pluripotency Factors in Mouse Embryonic Stem Cells.

Cell Rep 2015 Oct 24;13(1):52-60. Epub 2015 Sep 24.

Department of Molecular Biosciences, the University of Texas at Austin, Austin, TX 78712, USA; Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, the University of Texas at Austin, Austin, TX 78712, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.067DOI Listing
October 2015

Role of Zscan4 in secondary murine iPSC derivation mediated by protein extracts of ESC or iPSC.

Biomaterials 2015 Aug 15;59:102-15. Epub 2015 May 15.

National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea; Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul 110-744, Republic of Korea; Molecular Medicine & Biopharmaceutical Sciences, Seoul National University, Seoul 110-744, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.03.031DOI Listing
August 2015

Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming.

Stem Cell Reports 2015 Jun 21;4(6):1125-39. Epub 2015 May 21.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471828PMC
June 2015

X Chromosome of female cells shows dynamic changes in status during human somatic cell reprogramming.

Stem Cell Reports 2014 Jun 15;2(6):896-909. Epub 2014 May 15.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, 10 Amistad, 201B, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.stemcr.2014.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050354PMC
June 2014

Therapeutic potential of human induced pluripotent stem cells in experimental stroke.

Cell Transplant 2013 3;22(8):1427-40. Epub 2012 Oct 3.

CHA Stem Cell Institute, Department of Biomedical Science, CHA University, Seoul, Korea.

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http://dx.doi.org/10.3727/096368912X657314DOI Listing
April 2014

Investigation of Rett syndrome using pluripotent stem cells.

J Cell Biochem 2013 Nov;114(11):2446-53

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, 10 Amistad 201B, New Haven, Connecticut, 06520; Department of Biology and Biotechnology, Hashemite University, Zarqa, P.O. Box 150459 13133, Jordan.

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http://dx.doi.org/10.1002/jcb.24597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773984PMC
November 2013

Trivalent chromatin marks the way in.

Cell Stem Cell 2013 Nov;13(5):510-2

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, 10 Amistad, 201B, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.stem.2013.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665996PMC
November 2013

Development of a novel two-dimensional directed differentiation system for generation of cardiomyocytes from human pluripotent stem cells.

Int J Cardiol 2013 Sep 6;168(1):41-52. Epub 2012 Oct 6.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, United States.

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http://dx.doi.org/10.1016/j.ijcard.2012.09.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556195PMC
September 2013

Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells.

Blood 2013 Aug 3;122(7):1162-73. Epub 2013 Jun 3.

McMaster Stem Cell and Cancer Research Institute, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1182/blood-2012-12-471649DOI Listing
August 2013

Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction.

Cell Stem Cell 2013 Jun 18;12(6):727-36. Epub 2013 Apr 18.

Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.stem.2013.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755012PMC
June 2013

Modelling human disease with pluripotent stem cells.

Curr Gene Ther 2013 Apr;13(2):99-110

Stem Cell Epigenetics Laboratory, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo. PO Box 1112. Blindern. 0317 Oslo. Norway.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785403PMC
http://dx.doi.org/10.2174/1566523211313020004DOI Listing
April 2013

Impact of retrotransposons in pluripotent stem cells.

Mol Cells 2012 Dec 6;34(6):509-16. Epub 2012 Nov 6.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, 10 Amistad, 201B, New Haven, CT 06520, USA.

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http://link.springer.com/content/pdf/10.1007/s10059-012-0242
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http://link.springer.com/10.1007/s10059-012-0242-8
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http://dx.doi.org/10.1007/s10059-012-0242-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784326PMC
December 2012

Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells.

Circulation 2012 Oct 22;126(14):1695-704. Epub 2012 Aug 22.

YCVRC Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, Yale Stem Cell Center, Ste 773A, 300 George St, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.116996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586776PMC
October 2012

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.

Proc Natl Acad Sci U S A 2012 Oct 8;109(43):17567-72. Epub 2012 Oct 8.

Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1215468109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491455PMC
October 2012

Excision of a viral reprogramming cassette by delivery of synthetic Cre mRNA.

Curr Protoc Stem Cell Biol 2012 ;Chapter 4:Unit4A.5

Division of Pediatric Hematology Oncology, Children's Hospital Boston, and Dana-Farber Cancer Institute; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/9780470151808.sc04a05s21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397830PMC
September 2012

Cellular reprogramming: a novel tool for investigating autism spectrum disorders.

Trends Mol Med 2012 Aug 6;18(8):463-71. Epub 2012 Jul 6.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, 10 Amistad, 201B, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.molmed.2012.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785941PMC
August 2012

Overcoming reprogramming resistance of Fanconi anemia cells.

Blood 2012 Jun 27;119(23):5449-57. Epub 2012 Feb 27.

Division of Pediatric Hematology/Oncology, Children's Hospital Boston, and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1182/blood-2012-02-408674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369681PMC
June 2012

Human induced pluripotent stem cells and neurodegenerative disease: prospects for novel therapies.

Curr Opin Neurol 2012 Apr;25(2):125-30

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1097/WCO.0b013e3283518226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786112PMC
April 2012

Reprogramming human somatic cells into induced pluripotent stem cells (iPSCs) using retroviral vector with GFP.

J Vis Exp 2012 Apr 3(62). Epub 2012 Apr 3.

Yale Stem Cell Center, Department of Genetics, Yale School of Medicine.

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http://dx.doi.org/10.3791/3804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466658PMC
April 2012

Humanized murine model for HBV and HCV using human induced pluripotent stem cells.

Arch Pharm Res 2012 Feb 28;35(2):261-9. Epub 2012 Feb 28.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1007/s12272-012-0206-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731984PMC
February 2012

The lesser known story of X chromosome reactivation: a closer look into the reprogramming of the inactive X chromosome.

Cell Cycle 2012 Jan 15;11(2):229-35. Epub 2012 Jan 15.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.4161/cc.11.2.18998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293375PMC
January 2012

Cell cycle adaptations of embryonic stem cells.

Proc Natl Acad Sci U S A 2011 Nov 14;108(48):19252-7. Epub 2011 Nov 14.

Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1116794108
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http://dx.doi.org/10.1073/pnas.1116794108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228440PMC
November 2011

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.

Authors:
Katherine Amps Peter W Andrews George Anyfantis Lyle Armstrong Stuart Avery Hossein Baharvand Julie Baker Duncan Baker Maria B Munoz Stephen Beil Nissim Benvenisty Dalit Ben-Yosef Juan-Carlos Biancotti Alexis Bosman Romulo Martin Brena Daniel Brison Gunilla Caisander María V Camarasa Jieming Chen Eric Chiao Young Min Choi Andre B H Choo Daniel Collins Alan Colman Jeremy M Crook George Q Daley Anne Dalton Paul A De Sousa Chris Denning Janet Downie Petr Dvorak Karen D Montgomery Anis Feki Angela Ford Victoria Fox Ana M Fraga Tzvia Frumkin Lin Ge Paul J Gokhale Tamar Golan-Lev Hamid Gourabi Michal Gropp Guangxiu Lu Ales Hampl Katie Harron Lyn Healy Wishva Herath Frida Holm Outi Hovatta Johan Hyllner Maneesha S Inamdar Astrid Kresentia Irwanto Tetsuya Ishii Marisa Jaconi Ying Jin Susan Kimber Sergey Kiselev Barbara B Knowles Oded Kopper Valeri Kukharenko Anver Kuliev Maria A Lagarkova Peter W Laird Majlinda Lako Andrew L Laslett Neta Lavon Dong Ryul Lee Jeoung Eun Lee Chunliang Li Linda S Lim Tenneille E Ludwig Yu Ma Edna Maltby Ileana Mateizel Yoav Mayshar Maria Mileikovsky Stephen L Minger Takamichi Miyazaki Shin Yong Moon Harry Moore Christine Mummery Andras Nagy Norio Nakatsuji Kavita Narwani Steve K W Oh Sun Kyung Oh Cia Olson Timo Otonkoski Fei Pan In-Hyun Park Steve Pells Martin F Pera Lygia V Pereira Ouyang Qi Grace Selva Raj Benjamin Reubinoff Alan Robins Paul Robson Janet Rossant Ghasem H Salekdeh Thomas C Schulz Karen Sermon Jameelah Sheik Mohamed Hui Shen Eric Sherrer Kuldip Sidhu Shirani Sivarajah Heli Skottman Claudia Spits Glyn N Stacey Raimund Strehl Nick Strelchenko Hirofumi Suemori Bowen Sun Riitta Suuronen Kazutoshi Takahashi Timo Tuuri Parvathy Venu Yuri Verlinsky Dorien Ward-van Oostwaard Daniel J Weisenberger Yue Wu Shinya Yamanaka Lorraine Young Qi Zhou

Nat Biotechnol 2011 Nov 27;29(12):1132-44. Epub 2011 Nov 27.

Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK.

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http://www.nature.com/articles/nbt.2051
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http://dx.doi.org/10.1038/nbt.2051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454460PMC
November 2011

Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients.

Ann Neurol 2011 Sep 30;70(3):402-9. Epub 2011 Jun 30.

Department of Physiology, Brain Korea 21 Project for Medical Science and Severance Biomedical Science Institute, Seoul, Korea.

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http://dx.doi.org/10.1002/ana.22486DOI Listing
September 2011

Induced pluripotent stem cells for neural tissue engineering.

Biomaterials 2011 Aug 22;32(22):5023-32. Epub 2011 Apr 22.

Department of Bioengineering, University of California, Berkeley, B108A Stanley Hall, Berkeley, CA 94720-1762, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2011.03.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100451PMC
August 2011

Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome.

Proc Natl Acad Sci U S A 2011 Aug 1;108(34):14169-74. Epub 2011 Aug 1.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1073/pnas.1018979108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161557PMC
August 2011

Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.

PLoS One 2011 Apr 29;6(4):e18992. Epub 2011 Apr 29.

Department of Ophthalmology, Institute for Vision Research, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0018992PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084746PMC
April 2011

Analysis of differential proteomes of induced pluripotent stem cells by protein-based reprogramming of fibroblasts.

J Proteome Res 2011 Mar 4;10(3):977-89. Epub 2011 Feb 4.

Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1021/pr100624fDOI Listing
March 2011

Human pluripotent stem cells produce natural killer cells that mediate anti-HIV-1 activity by utilizing diverse cellular mechanisms.

J Virol 2011 Jan 20;85(1):43-50. Epub 2010 Oct 20.

Department of Medicine, University of Minnesota, 420 Delaware St. SE, MMC 480, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1128/JVI.01774-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014194PMC
January 2011

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells.

Nat Genet 2010 Dec 7;42(12):1113-7. Epub 2010 Nov 7.

Stem Cell Transplantation Program, Division of Pediatric Hematology and Oncology, Manton Center for Orphan Disease Research, Children's Hospital Boston and Dana Farber Cancer Institute, Boston, Massachusetts, USA.

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http://www.nature.com/articles/ng.710
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http://dx.doi.org/10.1038/ng.710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040650PMC
December 2010

Five classic articles in somatic cell reprogramming.

Authors:
In-Hyun Park

Yale J Biol Med 2010 Sep;83(3):135-7

Department of Genetics, Yale Stem Cell Center, Yale University School of Medicine, 10 Amistad 201B, New Haven, CT 06520, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946127PMC
September 2010

Reprogramming of T cells from human peripheral blood.

Cell Stem Cell 2010 Jul;7(1):15-9

Division of Pediatric Hematology Oncology, Department of Biological Chemistry and Molecular Pharmacology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.stem.2010.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913590PMC
July 2010

Robust enhancement of neural differentiation from human ES and iPS cells regardless of their innate difference in differentiation propensity.

Stem Cell Rev Rep 2010 Jun;6(2):270-81

Department of Physiology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, [corrected] Seoul, 120-752, Korea.

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http://dx.doi.org/10.1007/s12015-010-9138-1DOI Listing
June 2010

DYS-HAC-iPS cells: the combination of gene and cell therapy to treat duchenne muscular dystrophy.

Authors:
In-Hyun Park

Mol Ther 2010 Feb;18(2):238-40

Department of Genetics, Yale School of Medicine, Yale Stem Cell Center, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/mt.2009.303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839312PMC
February 2010

Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells.

Nat Biotechnol 2009 Nov 11;27(11):1033-7. Epub 2009 Oct 11.

Division of Pediatric Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.1580DOI Listing
November 2009

A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells.

PLoS Genet 2009 Nov 13;5(11):e1000718. Epub 2009 Nov 13.

Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766639PMC
November 2009

Cardiomyocyte differentiation of human induced pluripotent stem cells.

Circulation 2009 Oct 28;120(15):1513-23. Epub 2009 Sep 28.

Sohnis Family Research Laboratory for Cardiac Electrophysiology and Regenerative Medicine, the Rappaport Family Institute for Research in the Medical Sciences, Technion-Israel Institute of Technology, Haifa, Israel.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.109.868885DOI Listing
October 2009

Hematopoietic development from human induced pluripotent stem cells.

Ann N Y Acad Sci 2009 Sep;1176:219-27

Division of Hematology and Oncology, University of Tuebingen Medical Center II, Tuebingen, Germany.

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http://dx.doi.org/10.1111/j.1749-6632.2009.04606.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849804PMC
September 2009

A role for Lin28 in primordial germ-cell development and germ-cell malignancy.

Nature 2009 Aug 5;460(7257):909-13. Epub 2009 Jul 5.

Division of Pediatric Hematology/Oncology, Children's Hospital Boston and the Dana-Farber Cancer Institute, MA 02115, USA.

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http://www.nature.com/articles/nature08210
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http://dx.doi.org/10.1038/nature08210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729657PMC
August 2009

Generation of induced pluripotent stem cells from human blood.

Blood 2009 May 18;113(22):5476-9. Epub 2009 Mar 18.

Department of Medicine, Division of Pediatric Hematology Oncology, Children's Hospital Boston, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1182/blood-2009-02-204800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689048PMC
May 2009

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells.

Nat Biotechnol 2009 Apr 29;27(4):361-8. Epub 2009 Mar 29.

Department of Genetics, Harvard Medical School, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/nbt.1533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566772PMC
April 2009

Human iPS cell derivation/reprogramming.

Curr Protoc Stem Cell Biol 2009 Jan;Chapter 4:Unit 4A.1

Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Medical School, Harvard Stem Cell Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/9780470151808.sc04a01s8DOI Listing
January 2009

Generation of human-induced pluripotent stem cells.

Nat Protoc 2008 ;3(7):1180-6

Division of Pediatric Hematology Oncology, Children's Hospital Boston, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nprot.2008.92DOI Listing
September 2008

Disease-specific induced pluripotent stem cells.

Cell 2008 Sep 7;134(5):877-86. Epub 2008 Aug 7.

Department of Medicine, Division of Pediatric Hematology Oncology, Children's Hospital Boston, and Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cell.2008.07.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633781PMC
September 2008

Regulatory networks define phenotypic classes of human stem cell lines.

Nature 2008 Sep 24;455(7211):401-5. Epub 2008 Aug 24.

Center for Regenerative Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature07213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637443PMC
September 2008

Reprogramming of human somatic cells to pluripotency with defined factors.

Nature 2008 Jan 23;451(7175):141-6. Epub 2007 Dec 23.

Division of Pediatric Hematology/Oncology, Children's Hospital Boston and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature06534DOI Listing
January 2008

In vitro generation of germ cells from murine embryonic stem cells.

Nat Protoc 2006 ;1(4):2026-36

Graduate Program of Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nprot.2006.303DOI Listing
October 2007

Debugging cellular reprogramming.

Nat Cell Biol 2007 Aug;9(8):871-3

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http://dx.doi.org/10.1038/ncb0807-871DOI Listing
August 2007

A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.

J Biol Chem 2006 Mar 9;281(11):7357-63. Epub 2006 Jan 9.

Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, 601 S. Goodwin Avenue, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1074/jbc.M512218200DOI Listing
March 2006

Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1.

Exp Cell Res 2005 Sep;309(1):211-9

Department of Cell and Structural Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1016/j.yexcr.2005.05.017DOI Listing
September 2005

Mammalian target of rapamycin (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation.

J Biol Chem 2005 Sep 25;280(36):32009-17. Epub 2005 Jul 25.

Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1074/jbc.M506120200DOI Listing
September 2005

PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.

Curr Biol 2003 Dec;13(23):2037-44

Department of Cell and Structural Biology, University of Illinois at Urbana-Champaign, 601 S. Goodwin Avenue B107, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1016/j.cub.2003.11.021DOI Listing
December 2003

IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients.

J Cell Biol 2003 Dec;163(5):931-6

Department of Cell and Structural Biology, University of Illinois at Urbana-Champaign, 601 S. Goodwin Ave., B107, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1083/jcb.200307158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173600PMC
December 2003

Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin.

J Biol Chem 2002 Aug 26;277(35):31423-9. Epub 2002 Jun 26.

Department of Cell and Structural Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1074/jbc.M204080200DOI Listing
August 2002