Publications by authors named "In-Gyu Kim"

145Publications

Transglutaminase 2 crosslinks the glutathione S-transferase tag, impeding protein-protein interactions of the fused protein.

Authors:
Hyo-Jun Kim Jin-Haeng Lee Ki Baek Lee Ji-Woong Shin Mee-Ae Kwon Soojin Lee Eui Man Jeong Sung-Yup Cho In-Gyu Kim

Exp Mol Med 2021 Jan 13. Epub 2021 Jan 13.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea.

View Article and Find Full Text PDF
January 2021

HSPA1L Enhances Cancer Stem Cell-Like Properties by Activating IGF1Rβ and Regulating β-Catenin Transcription.

Authors:
Soo-Im Choi Jei-Ha Lee Rae-Kwon Kim Uhee Jung Yeon-Jee Kahm Eun-Wie Cho In-Gyu Kim

Int J Mol Sci 2020 Sep 22;21(18). Epub 2020 Sep 22.

Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, Daejeon 34057, Korea.

View Article and Find Full Text PDF
September 2020

F-fluorodeoxyglucose PET/CT as an independent predictor for patients with hepatocellular carcinoma combined with major portal vein tumor thrombus.

Authors:
Xu-Guang Hu Xue-Yin Shen Jin-Niang Nan In-Gyu Kim Joon-Kee Yoon Sung-Yeon Hong Mi-Na Kim Bong-Wan Kim Hee-Jung Wang

Ann Surg Treat Res 2020 Jul 29;99(1):8-17. Epub 2020 Jun 29.

Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Ajou University School of Medicine, Suwon, Korea.

View Article and Find Full Text PDF
July 2020

Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway.

Authors:
Jisun Lim Jinbeom Heo Hyein Ju Ji-Woong Shin YongHwan Kim Seungun Lee Hwan Yeul Yu Chae-Min Ryu HongDuck Yun Sujin Song Ki-Sung Hong Hyung-Min Chung Hwa-Ryeon Kim Jae-Seok Roe Kihang Choi In-Gyu Kim Eui Man Jeong Dong-Myung Shin

Sci Adv 2020 Apr 15;6(16):eaba1334. Epub 2020 Apr 15.

Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

View Article and Find Full Text PDF
April 2020

Antioxidants reduce the heterogeneity of the intracellular glutathione level in senescent cell population of human dermal fibroblasts.

Authors:
Ki Baek Lee Ji-Woong Shin Mee-Ae Kwon Hyewon Kang Hye-Mi Kim Seok-Jin Lee Eui Man Jeong Heun-Soo Kang In-Gyu Kim

J Dermatol Sci 2020 Jun 24;98(3):195-198. Epub 2020 Apr 24.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
June 2020

Keratinocyte transglutaminase 2 promotes CCR6 γδT-cell recruitment by upregulating CCL20 in psoriatic inflammation.

Authors:
Ji-Woong Shin Mee-Ae Kwon Jinha Hwang Seok-Jin Lee Jin-Haeng Lee Hyo-Jun Kim Ki Baek Lee Soo-Jin Lee Eui Man Jeong Jin Ho Chung In-Gyu Kim

Cell Death Dis 2020 04 30;11(4):301. Epub 2020 Apr 30.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.

View Article and Find Full Text PDF
April 2020

Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs.

Authors:
Sung-Yup Cho Seungun Lee Jeonghun Yeom Hyo-Jun Kim Jin-Haeng Lee Ji-Woong Shin Mee-Ae Kwon Ki Baek Lee Eui Man Jeong Hee Sung Ahn Dong-Myung Shin Kyunggon Kim In-Gyu Kim

Life Sci Alliance 2020 03 19;3(3). Epub 2020 Feb 19.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

View Article and Find Full Text PDF
March 2020

Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2.

Authors:
Eui Man Jeong Ki Baek Lee Gi Eob Kim Chang Min Kim Jin-Haeng Lee Hyo-Jun Kim Ji-Woong Shin Mee-Ae Kwon Hyun Ho Park In-Gyu Kim

Int J Mol Sci 2020 Jan 25;21(3). Epub 2020 Jan 25.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.

View Article and Find Full Text PDF
January 2020

Monitoring Glutathione Dynamics and Heterogeneity in Living Stem Cells.

Authors:
Eui Man Jeong Ji-Woong Shin Jisun Lim Ju Hwan Kim Hyewon Kang Yingfu Yin Hye-Mi Kim YongHwan Kim Sun-Gi Kim Heun-Soo Kang Dong-Myung Shin Kihang Choi In-Gyu Kim

Int J Stem Cells 2019 Jul;12(2):367-379

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea.

View Article and Find Full Text PDF
July 2019

The 7th/8th American Joint Committee on Cancer and the Modified Union for International Cancer Control Staging System for Hepatocellular Carcinoma.

Authors:
In Gyu Kim Xu Guang Hu Hee Jung Wang Bong Wan Kim Sung Yeon Hong Xue Yin Shen

Yonsei Med J 2019 Feb;60(2):140-147

Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, Ajou University School of Medicine, Suwon, Korea.

View Article and Find Full Text PDF
February 2019

Exercise training increases skeletal muscle strength independent of hypertrophy in older adults aged 75 years and older.

Authors:
Hojun Lee In-Gyu Kim Changsu Sung Tae-Bong Jeon Kibum Cho Yong-Chan Ha Ki-Soo Park Jun-Il Yoo Gyeong Hui Kang Su Jin Kim Ji-Seok Kim

Geriatr Gerontol Int 2019 Mar 8;19(3):265-270. Epub 2019 Jan 8.

Department of Physical Education, Gyeongsang National University, Jinju, Korea.

View Article and Find Full Text PDF
March 2019

Structure of natural variant transglutaminase 2 reveals molecular basis of gaining stability and higher activity.

Authors:
Hyun Ji Ha Sunghark Kwon Eui Man Jeong Chang Min Kim Ki Baek Lee In-Gyu Kim Hyun Ho Park

PLoS One 2018 15;13(10):e0204707. Epub 2018 Oct 15.

School of Pharmacy, Chung-Ang University, Seoul, South Korea.

View Article and Find Full Text PDF
March 2019

Hypoxia-inducible transgelin 2 selects epithelial-to-mesenchymal transition and γ-radiation-resistant subtypes by focal adhesion kinase-associated insulin-like growth factor 1 receptor activation in non-small-cell lung cancer cells.

Authors:
In-Gyu Kim Jei-Ha Lee Seo-Yeon Kim Hai-Min Hwang Tae-Rim Kim Eun-Wie Cho

Cancer Sci 2018 Nov 10;109(11):3519-3531. Epub 2018 Oct 10.

Rare Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.

View Article and Find Full Text PDF
November 2018

Tescalcin/c-Src/IGF1Rβ-mediated STAT3 activation enhances cancer stemness and radioresistant properties through ALDH1.

Authors:
Jei Ha Lee Soo Im Choi Rae Kwon Kim Eun Wie Cho In Gyu Kim

Sci Rep 2018 Jul 16;8(1):10711. Epub 2018 Jul 16.

Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, 111, Daedeok-Daero 989 Beon-Gil, Yuseong-Gu, Daejeon, Korea.

View Article and Find Full Text PDF
July 2018

S-nitrosylation of transglutaminase 2 impairs fatty acid-stimulated contraction in hypertensive cardiomyocytes.

Authors:
Eui Man Jeong Chun Zi Jin Ji Hyun Jang Zai Hao Zhao Chun Li Jin Jin Hang Lee Ki Baek Lee Sung Joon Kim In-Gyu Kim Yin Hua Zhang

Exp Mol Med 2018 04 6;50(4). Epub 2018 Apr 6.

Department of Physiology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Jongno-gu, Seoul, Republic of Korea.

View Article and Find Full Text PDF
April 2018

Shikonin induces mitochondria-mediated apoptosis and attenuates epithelial-mesenchymal transition in cisplatin-resistant human ovarian cancer cells.

Authors:
Kristina Shilnikova Mei Jing Piao Kyoung Ah Kang Yea Seong Ryu Jeong Eon Park Yu Jae Hyun Ao Xuan Zhen Yong Joo Jeong Uhee Jung In Gyu Kim Jin Won Hyun

Oncol Lett 2018 Apr 15;15(4):5417-5424. Epub 2018 Feb 15.

Department of Biochemistry, School of Medicine, Jeju National University, Jeju 63243, Republic of Korea.

View Article and Find Full Text PDF
April 2018

Proinvasive extracellular matrix remodeling in tumor microenvironment in response to radiation.

Authors:
Ki-Chun Yoo Yongjoon Suh Yoojeong An Hae-June Lee Ye Ji Jeong Nizam Uddin Yan-Hong Cui Tae-Hoon Roh Jin-Kyoung Shim Jong Hee Chang Jong Bae Park Min-Jung Kim In-Gyu Kim Seok-Gu Kang Su-Jae Lee

Oncogene 2018 06 21;37(24):3317-3328. Epub 2018 Mar 21.

Department of Life Science, Research Institute for Natural Sciences, Hanyang University, Seoul, 04763, Korea.

View Article and Find Full Text PDF
June 2018

FYN promotes mesenchymal phenotypes of basal type breast cancer cells through STAT5/NOTCH2 signaling node.

Authors:
Ga-Hang Lee Ki-Chun Yoo Yoojeong An Hae-June Lee Minyoung Lee Nizam Uddin Min-Jung Kim In-Gyu Kim Yongjoon Suh Su-Jae Lee

Oncogene 2018 04 19;37(14):1857-1868. Epub 2018 Jan 19.

Department of Life Science, Research Institute for Natural Sciences, Hanyang University, Seoul, Korea.

View Article and Find Full Text PDF
April 2018

Real-Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function.

Authors:
Eui Man Jeong Ji-Hye Yoon Jisun Lim Ji-Woong Shin A Young Cho Jinbeom Heo Ki Baek Lee Jin-Haeng Lee Won Jong Lee Hyo-Jun Kim Young Hoon Son Seok-Jin Lee Sung-Yup Cho Dong-Myung Shin Kihang Choi In-Gyu Kim

Stem Cell Reports 2018 02 4;10(2):600-614. Epub 2018 Jan 4.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Institute of Human-Environment Interface Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
February 2018

Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells.

Authors:
Soo Im Choi Seo Yoen Kim Jei Ha Lee Jung Yul Kim Eun Wie Cho In-Gyu Kim

Oncotarget 2017 Nov 18;8(60):101284-101297. Epub 2017 Sep 18.

Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, Yuseong-Gu, Daejeon 34057, Korea.

View Article and Find Full Text PDF
November 2017