Imo E Hoefer

Imo E Hoefer

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Imo E Hoefer

Publications by authors named "Imo E Hoefer"

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Local inflammatory responses take their toll on the heart.

Int J Cardiol 2019 Jul 22. Epub 2019 Jul 22.

Laboratory for Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, the Netherlands.. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.07.055DOI Listing
July 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Authors:
Riyaz S Patel Vinicius Tragante Amand F Schmidt Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behloui Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Marie-Pierre Dubé Line Dufresne Niclas Eriksson Luisa Foco Markus Scholz Crystel M Gijsberts Charlotte Glinge Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Salma Kotti Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica Van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Lawien Al Ali Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Thomas Engstrøm Natalie Fitzpatrick Kim Fox Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Christopher Newton-Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Eric H Boersma Peter Bogaty Michiel L Bots Hermann Brenner Jasper J Brugts Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Nicolas Danchin Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Diederick E Grobbee Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Reza Jabbari Julie A Johnson J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm B K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Anna Niemcunowicz-Janica Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Agneta Siegbahn Tabassome Simon Juha Sinisalo J Gustav Smith John A Spertus Steen Stender Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jean-Claude Tardif Jurriën M Ten Berg Jacob Tfelt-Hansen George Thanassoulis Joachim Thiery Christian Torp-Pedersen Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Peter E Weeke Pim Van der Harst Chim C Lang Naveed Sattar Vicky A Cameron Jeffrey L Anderson James M Brophy Guillaume Pare Benjamin D Horne Winfried März Lars Wallentin Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 Apr 21;12(4):e002470. Epub 2019 Mar 21.

Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.119.002470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629546PMC
April 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Authors:
Riyaz S Patel Amand F Schmidt Vinicius Tragante Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Marie-Pierre Dubé Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behlouli Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Line Dufresne Niclas Eriksson Luisa Foco Crystel M Gijsberts Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Natalie Fitzpatrick Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Chris Newton Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Peter Bogaty Gert J de Borst Hermann Brenner Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Julie A Johnson Pim A de Jong J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm Bakhtawar K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Witold Pepinski Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Markus Scholz Agneta Siegbahn Juha Sinisalo J Gustav Smith John A Spertus Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jurriën M Ten Berg George Thanassoulis Joachim Thiery Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Pim Van der Harst Jean-Claude Tardif Naveed Sattar Chim C Lang Guillaume Pare James M Brophy Jeffrey L Anderson Winfried März Lars Wallentin Vicky A Cameron Benjamin D Horne Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 Apr 21;12(4):e002471. Epub 2019 Mar 21.

Institute of Cardiovascular Science, Faculty of Population Health Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A.).

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http://dx.doi.org/10.1161/CIRCGEN.119.002471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625876PMC
April 2019

A Human(e) Factor in Clinical Decision Support Systems.

J Med Internet Res 2019 Mar 19;21(3):e11732. Epub 2019 Mar 19.

Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

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http://dx.doi.org/10.2196/11732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444220PMC
March 2019

Testosterone to oestradiol ratio reflects systemic and plaque inflammation and predicts future cardiovascular events in men with severe atherosclerosis.

Cardiovasc Res 2019 Feb;115(2):453-462

Laboratory of Experimental Cardiology, University Medical Center Utrecht, University of Utrecht, Heidelberglaan 100, CX Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvy188DOI Listing
February 2019

Circulating CD14CD16 classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients.

J Mol Cell Cardiol 2019 Feb 7;127:260-269. Epub 2019 Jan 7.

Laboratory for Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222828193001
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http://dx.doi.org/10.1016/j.yjmcc.2019.01.002DOI Listing
February 2019

Renin and aldosterone are not associated with vulnerable plaque characteristics in patients with carotid artery disease.

J Vasc Surg 2018 07 13;68(1):128-135. Epub 2018 Mar 13.

Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jvs.2017.05.117DOI Listing
July 2018

Janus revisited: The intricate role of the immune system in neovascularization.

Int J Cardiol 2018 06;260:193-194

Laboratory of Experimental Cardiology, UMC Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.ijcard.2018.03.014DOI Listing
June 2018

Beyond the matrix: MMP2 as critical regulator of inflammation-mediated vascular dysfunction.

Cardiovasc Res 2017 12;113(14):1705-1707

Laboratory for Experimental Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvx202DOI Listing
December 2017

Preclinical Testing of Frequency-Tunable Capacitive Micromachined Ultrasonic Transducer Probe Prototypes.

Ultrasound Med Biol 2017 09 20;43(9):2079-2085. Epub 2017 Jun 20.

Erasmus MC, Thorax Center Department of Biomedical Engineering, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2017.05.005DOI Listing
September 2017

Effect of Monocyte-to-Lymphocyte Ratio on Heart Failure Characteristics and Hospitalizations in a Coronary Angiography Cohort.

Am J Cardiol 2017 Sep 29;120(6):911-916. Epub 2017 Jun 29.

Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands; ICIN-Netherlands Heart Institute, The Netherlands; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Cardiovascular Research Institute (CVRI), National University Heart Center (NUHCS), National University Health System, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2017.06.020DOI Listing
September 2017

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets.

Cancer Cell 2017 08;32(2):238-252.e9

Department of Neurosurgery, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Brain Tumor Center Amsterdam, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, 149 13(th) Street, Charlestown, MA 02129, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381325PMC
August 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Authors:
Stephen Zewinger Marcus E Kleber Vinicius Tragante Raymond O McCubrey Amand F Schmidt Kenan Direk Ulrich Laufs Christian Werner Wolfgang Koenig Dietrich Rothenbacher Ute Mons Lutz P Breitling Herrmann Brenner Richard T Jennings Ioannis Petrakis Sarah Triem Mira Klug Alexandra Filips Stefan Blankenberg Christoph Waldeyer Christoph Sinning Renate B Schnabel Karl J Lackner Efthymia Vlachopoulou Ottar Nygård Gard Frodahl Tveitevåg Svingen Eva Ringdal Pedersen Grethe S Tell Juha Sinisalo Markku S Nieminen Reijo Laaksonen Stella Trompet Roelof A J Smit Naveed Sattar J Wouter Jukema Heinrich V Groesdonk Graciela Delgado Tatjana Stojakovic Anna P Pilbrow Vicky A Cameron A Mark Richards Robert N Doughty Yan Gong Rhonda Cooper-DeHoff Julie Johnson Markus Scholz Frank Beutner Joachim Thiery J Gustav Smith Ragnar O Vilmundarson Ruth McPherson Alexandre F R Stewart Sharon Cresci Petra A Lenzini John A Spertus Oliviero Olivieri Domenico Girelli Nicola I Martinelli Andreas Leiherer Christoph H Saely Heinz Drexel Axel Mündlein Peter S Braund Christopher P Nelson Nilesh J Samani Daniel Kofink Imo E Hoefer Gerard Pasterkamp Arshed A Quyyumi Yi-An Ko Jaana A Hartiala Hooman Allayee W H Wilson Tang Stanley L Hazen Niclas Eriksson Claes Held Emil Hagström Lars Wallentin Axel Åkerblom Agneta Siegbahn Igor Karp Christopher Labos Louise Pilote James C Engert James M Brophy George Thanassoulis Peter Bogaty Wojciech Szczeklik Marcin Kaczor Marek Sanak Salim S Virani Christie M Ballantyne Vei-Vei Lee Eric Boerwinkle Michael V Holmes Benjamin D Horne Aroon Hingorani Folkert W Asselbergs Riyaz S Patel Bernhard K Krämer Hubert Scharnagl Danilo Fliser Winfried März Thimoteus Speer

Lancet Diabetes Endocrinol 2017 07 26;5(7):534-543. Epub 2017 May 26.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/S2213-8587(17)30096-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651679PMC
July 2017

Prognostic Value of Circulating Inflammatory Cells in Patients with Stable and Acute Coronary Artery Disease.

Front Cardiovasc Med 2017 14;4:44. Epub 2017 Jul 14.

Laboratory for Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.3389/fcvm.2017.00044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509763PMC
July 2017

Microvesicles in vascular homeostasis and diseases. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology.

Thromb Haemost 2017 06 1;117(7):1296-1316. Epub 2017 Jun 1.

Victoria Ridger, PhD, Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK, E-mail: or, Chantal M. Boulanger, PhD, INSERM UMR-S 970, Paris Cardiovascular Research Center - PARCC, 56 rue Leblanc, 75015 Paris, France, E-mail:

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http://dx.doi.org/10.1160/TH16-12-0943DOI Listing
June 2017

The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction.

Eur Heart J 2017 Mar;38(11):828-836

Experimental Cardiology Laboratory (Room G02.523), University Medical Center Utrecht, Heidelberglaan 100, PO Box 85500, Utrecht 3508 GA, The Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehw247DOI Listing
March 2017

Total Arterial Minimally Invasive Direct Coronary Artery Bypass Surgery Facilitated by the Trinity Clip Connector.

Innovations (Phila) 2015 Nov-Dec;10(6):389-93

From the *Department of Cardiothoracic Surgery, Heart and Lungs Division, University Medical Center Utrecht, Utrecht, The Netherlands; †Corvasco Medical, Utrecht, The Netherlands; and ‡Experimental Cardiology, Heart and Lungs Division, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/IMI.0000000000000219DOI Listing
October 2016

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction.

J Vis Exp 2016 10 14(116). Epub 2016 Oct 14.

Department of Experimental Cardiology, University Medical Center Utrecht; Department of Clinical Chemistry and Hematology, University Medical Center Utrecht.

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http://dx.doi.org/10.3791/54021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092202PMC
October 2016

Targeting danger-associated molecular patterns after myocardial infarction.

Expert Opin Ther Targets 2016 30;20(2):223-39. Epub 2015 Sep 30.

a 1 University Medical Center Utrecht, Experimental Cardiology Laboratory , Utrecht, The Netherlands ;

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http://dx.doi.org/10.1517/14728222.2016.1088005DOI Listing
September 2016

Panta rhei: Everything flows - flow is everything Comment on Buschmann et al, p. 317 - 324.

Authors:
Imo E Hoefer

Vasa 2016 ;45(4):265-6

1 Laboratory of Clinical Chemistry and Haematology, UMC Utrecht, the Netherland.

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http://dx.doi.org/10.1024/0301-1526/a000536DOI Listing
September 2016

Routinely analyzed leukocyte characteristics improve prediction of mortality after coronary angiography.

Eur J Prev Cardiol 2016 07 7;23(11):1211-20. Epub 2015 Dec 7.

Experimental Cardiology Laboratory, University Medical Center Utrecht, Utrecht, The Netherlands Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands

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http://dx.doi.org/10.1177/2047487315621832DOI Listing
July 2016

Health-related quality of life and outcome in atherosclerosis - Does sex matter?

Int J Cardiol 2016 Jun 24;212:303-6. Epub 2016 Mar 24.

Experimental Cardiology Laboratory, University Medical Center Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.03.149DOI Listing
June 2016

Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype.

Arterioscler Thromb Vasc Biol 2016 06 14;36(6):1240-6. Epub 2016 Apr 14.

From the Laboratory of Experimental Cardiology, Division Heart and Lungs (G.P., S.W.v.d.L., S.H., M.A.S., T.B., J.v.S., I.E.H., S.C.A.d.J., H.M.d.R.), Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy (G.P.), and Division Heart and Lungs, Department of Cardiology (F.W.A.), University Medical Center Utrecht, Utrecht, The Netherlands; Vascular Biology Unit, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden (H.F.A., J.L.M.B.); Institut für Schlaganfall- und Demenzforschung (ISD) Klinikum der Universität München, Munich, Germany (M.D., R.M.); Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (M.D.); Department of Neurology, University of Virginia, Charlottesville (B.B.W.); Klinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany (H.S.); Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) e.V., Partner Site Munich Heart Alliance, Munich, Germany (H.S.); Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom (N.J.S.); Leicester National Institute of Health Research Biomedical Research Unit in Cardiovascular Disease, Leicester, United Kingdom (N.J.S.); Department of Surgery, National University of Singapore, Singapore (D.P.V.d.K.); Cardiovascular Research Institute (CVRI), National University Health System, Singapore, Singapore (D.P.V.d.K.); Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (D.P.V.d.K.); Department of Neurosciences, University of Cambridge, Cambridge, United Kingdom (H.S.M.); The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom (T.M.); Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY (J.L.M.B.); Department of Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estoni

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http://dx.doi.org/10.1161/ATVBAHA.115.306958DOI Listing
June 2016

Beware of the content!-exosomes as benefactors and agitators.

Authors:
Imo E Hoefer

Cardiovasc Res 2016 06 21;110(3):293-4. Epub 2016 Apr 21.

Laboratory of Clinical Chemistry and Hematology, UMC Utrecht, G03.550, Heidelberglaan 100, Utrecht 3584CX, The Netherlands

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http://dx.doi.org/10.1093/cvr/cvw088DOI Listing
June 2016

A membrane-based microfluidic device for mechano-chemical cell manipulation.

Biomed Microdevices 2016 Apr;18(2):31

Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.

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http://dx.doi.org/10.1007/s10544-016-0040-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778142PMC
April 2016

Translational failure of anti-inflammatory compounds for myocardial infarction: a meta-analysis of large animal models.

Cardiovasc Res 2016 Feb 20;109(2):240-8. Epub 2015 Oct 20.

Experimental Cardiology Laboratory, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584CX, The Netherlands Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvv239DOI Listing
February 2016

Platelet density per monocyte predicts adverse events in patients after percutaneous coronary intervention.

Thromb Haemost 2016 Jan 1;115(2):353-60. Epub 2015 Oct 1.

Dr. Bert Rutten, Department of Clinical Chemistry and Haematology, UMC Utrecht, Utrecht, the Netherlands, E-mail:

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http://dx.doi.org/10.1160/TH15-03-0227DOI Listing
January 2016

Development and evaluation of in vivo tissue engineered blood vessels in a porcine model.

Biomaterials 2016 Jan 22;75:82-90. Epub 2015 Oct 22.

Department of Nephrology, Leiden University Medical Center, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.10.023DOI Listing
January 2016

Biomarkers of Coronary Artery Disease Differ Between Asians and Caucasians in the General Population.

Glob Heart 2015 Dec 7;10(4):301-311.e11. Epub 2015 Mar 7.

Laboratory of Experimental Cardiology, University Medical Centre Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.gheart.2014.11.004DOI Listing
December 2015

Relation Between Circulating Inflammatory Chemokines and Vascular Characteristics in Healthy, Young Children.

J Am Heart Assoc 2015 Dec 16;4(12). Epub 2015 Dec 16.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands (C.M.U., M.L.B., G.W.D.).

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http://dx.doi.org/10.1161/JAHA.115.002346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845277PMC
December 2015

The multifaceted functions of CXCL10 in cardiovascular disease.

Biomed Res Int 2014 23;2014:893106. Epub 2014 Apr 23.

Laboratory of Experimental Cardiology, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands ; Interuniversity Cardiology Institute of the Netherlands, P.O. Box 19258, 3501 DG, Utrecht, The Netherlands.

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http://dx.doi.org/10.1155/2014/893106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017714PMC
November 2015

Hematological Parameters Improve Prediction of Mortality and Secondary Adverse Events in Coronary Angiography Patients: A Longitudinal Cohort Study.

Medicine (Baltimore) 2015 Nov;94(45):e1992

From the Experimental Cardiology Laboratory, University Medical Center Utrecht (CMG, HMDR, DPVDK, GP, IEH); ICIN-Netherlands Heart Institute, Utrecht, The Netherlands (CMG, DPVDK); Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore (DPVDK); Cardiovascular Research Institute (CVRI), National University Heart Centre (NUHCS), National University Health System, Singapore, Singapore (DPVDK); Department of Clinical Chemistry and Hematology (AH, MJTB, RHAVW, WWVS, IEH); Department of Cardiology, University Medical Center Utrecht (FWA, MV); Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands (FWA); and Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK (FWA).

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http://dx.doi.org/10.1097/MD.0000000000001992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912281PMC
November 2015

Circulating endothelial cells in coronary artery disease and acute coronary syndrome.

Trends Cardiovasc Med 2015 Oct 7;25(7):578-87. Epub 2015 Feb 7.

Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands; Laboratory of Clinical Chemistry and Hematology, University Medical Center Utrecht, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10501738150003
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http://dx.doi.org/10.1016/j.tcm.2015.01.013DOI Listing
October 2015

Novel methodologies for biomarker discovery in atherosclerosis.

Eur Heart J 2015 Oct 5;36(39):2635-42. Epub 2015 Jun 5.

Ludwig-Maximilians-University, G02.523, Heidelberglaan 100, 3584CX Munich, Germany German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.

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http://eurheartj.oxfordjournals.org/content/ehj/36/39/2635.f
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http://eurheartj.oxfordjournals.org/lookup/doi/10.1093/eurhe
Publisher Site
http://dx.doi.org/10.1093/eurheartj/ehv236DOI Listing
October 2015

Gender differences in health-related quality of life in patients undergoing coronary angiography.

Open Heart 2015 27;2(1):e000231. Epub 2015 Aug 27.

Laboratory of Experimental Cardiology, Division Heart and Lungs , University Medical Centre Utrecht , Utrecht , The Netherlands.

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http://dx.doi.org/10.1136/openhrt-2014-000231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555073PMC
September 2015

Severity of stable coronary artery disease and its biomarkers differ between men and women undergoing angiography.

Atherosclerosis 2015 Jul 4;241(1):234-40. Epub 2015 Feb 4.

Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Centre Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.02.002DOI Listing
July 2015

Endogenous contrast MRI of cardiac fibrosis: beyond late gadolinium enhancement.

J Magn Reson Imaging 2015 May 5;41(5):1181-9. Epub 2014 Aug 5.

Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/jmri.24715DOI Listing
May 2015

Common carotid intima-media thickness relates to cardiovascular events in adults aged <45 years.

Hypertension 2015 Apr 26;65(4):707-13. Epub 2015 Jan 26.

From the Department of Radiology (A.L.M.E.), Department of Cardiovascular Epidemiology, Julius Center for Health Sciences and Primary Care (K.A.G., D.E.G., S.A.E.P., M.L.B., H.M.d.R.), and Department of Experimental Cardiology (I.E.H., H.M.d.R.), University Medical Center, Utrecht, Utrecht, The Netherlands; Department of Cardiac Sciences and Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (T.J.A.); Department of Epidemiology and Public Health University College London, London, United Kingdom (A.R.B.); Department of Clinical Sciences in Malmö, Lund University, Skåne University Hospital, Malmö, Sweden (G.E., B.H., M.R.); Department of Biostatistical Sciences and Neurology, Wake Forest School of Medicine, Winston-Salem, NC (G.W.E.); Division of Vascular Medicine, Department of General Internal Medicine, Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands (J.d.G., S.H.); Department of Clinical Epidemiology, University of Malaya Medical Center, Kuala Lumpur, Malaysia (D.E.G.); Osaka Medical Center for Health Science and Promotion, Osaka, Japan (A.I., A.K.); Department of Neurology, Tokyo Women Medical University, Tokyo, Japan (K.K.); Division of Cardiology and Population Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada (E.M.L.); Department of Neurology, University Hospital, Goethe-University, Frankfurt am Main, Germany (M.W.L., M.S.); Brain and Circulation Research Group, Department of Clinical Medicine, University of Tromsø, Tromsø, Norway (E.B.M.); Department of General Practice, EMGO Institute, VU Medical Center, Amsterdam, The Netherlands (G.N., J.M.D.); Stroke Center, Department of Neurology, Osaka University Graduate School of Medicine, Osaka, Japan (S.O.); Department of Radiology, Tufts Medical Center, Boston, MA (D.H.O'L., J.F.P.); Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom (J.F.P., C.R.); Cardiology Division, De

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04658DOI Listing
April 2015

Monocyte hyporesponsiveness and Toll-like receptor expression profiles in coronary artery bypass grafting and its clinical implications for postoperative inflammatory response and pneumonia: An observational cohort study.

Eur J Anaesthesiol 2015 Mar;32(3):177-88

From the Department of Anaesthesiology, University Medical Center Utrecht (UMCU), Utrecht (SF, THK), Department of Rheumatology and Clinical Immunology, UMCU, Utrecht (ANC), Department of Clinical Microbiology, Admiraal de Ruyter Ziekenhuis, Goes (DV), Division of Heart and Lung, Experimental Cardiology Laboratory, UMCU, Utrecht (IEH, GP), Department of Intensive Care Medicine and Department of Emergency Medicine, UMCU, Utrecht (DWDL) and Department of Anaesthesiology and Pain Medicine, University Medical Center Maastricht, Maastricht, the Netherlands (WFB).

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http://dx.doi.org/10.1097/EJA.0000000000000184DOI Listing
March 2015

Necrostatin-1 alleviates reperfusion injury following acute myocardial infarction in pigs.

Eur J Clin Invest 2015 Feb 13;45(2):150-9. Epub 2015 Jan 13.

Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands; Interuniversity Cardiology Institute of the Netherlands (ICIN), Utrecht, the Netherlands.

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http://dx.doi.org/10.1111/eci.12391DOI Listing
February 2015

Six-month healing of the nonocclusive coronary anastomotic connector in an off-pump porcine bypass model.

Innovations (Phila) 2014 Mar-Apr;9(2):130-6; discussion 136

From the Departments of *Cardiothoracic Surgery, †Cardiology, and ‡Experimental Cardiology, Heart and Lungs Division, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/IMI.0000000000000055DOI Listing
January 2015

Popliteal artery aneurysms differ from abdominal aortic aneurysms in cellular topography and inflammatory markers.

J Vasc Surg 2014 Dec 3;60(6):1514-9. Epub 2014 Oct 3.

Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jvs.2014.08.088DOI Listing
December 2014

Extracellular vesicle protein CD14 relates to common carotid intima-media thickness in eight-year-old children.

Atherosclerosis 2014 Oct 28;236(2):270-6. Epub 2014 Jul 28.

Julius Center for Health Sciences and Primary Care, University Medical Center, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.07.018DOI Listing
October 2014

Intracoronary infusion of encapsulated glucagon-like peptide-1-eluting mesenchymal stem cells preserves left ventricular function in a porcine model of acute myocardial infarction.

Circ Cardiovasc Interv 2014 Oct 7;7(5):673-83. Epub 2014 Oct 7.

From the Department of Cardiology, Thorax Center, Erasmus University Medical Center, Rotterdam, The Netherlands (R.d.J., J.H.H., K.K.); Experimental Cardiology Laboratory, University and Medical Center Utrecht, The Netherlands (G.P.J.v.H., G.P., I.E.H.); BTG International Germany GmbH, Alzenau, Germany (C.W.); Biocompatibles UK Ltd, a BTG International Group Company, Farnham, United Kingdom (A.L.); and Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands (H.J.D.).

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.114.001580DOI Listing
October 2014

The nonocclusive laser-assisted coronary anastomotic connector in an off-pump porcine bypass model.

J Thorac Cardiovasc Surg 2014 Apr 29;147(4):1390-1397.e2. Epub 2013 Aug 29.

Department of Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jtcvs.2013.07.018DOI Listing
April 2014

Innate collateral segments are predominantly present in the subendocardium without preferential connectivity within the left ventricular wall.

J Physiol 2014 Mar 23;592(5):1047-60. Epub 2013 Dec 23.

Department of Biomedical Engineering and Physics, Academic Medical Center - University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1113/jphysiol.2013.258855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948562PMC
March 2014

Absence of chemokine (C-x-C motif) ligand 10 diminishes perfusion recovery after local arterial occlusion in mice.

Arterioscler Thromb Vasc Biol 2014 Mar 9;34(3):594-602. Epub 2014 Jan 9.

From the Laboratory of Experimental Cardiology (P.v.d.B., R.T.H., I.E.H., G.P., D.P.V.d.K.), Department of Nephrology and Hypertension (C.C.), and Department of Cardiology (H.J.D.), University Medical Center Utrecht, Utrecht, The Netherlands; Molecular Cardiology Laboratory, Experimental Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands (M.M.B., C.C.); Department of Surgery (P.H.A.Q.) and Einthoven Laboratory of Experimental Vascular Medicine (P.H.A.Q.), Leiden University Medical Center, Leiden, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (I.E.H., G.P., D.P.V.d.K.); and Cardiovascular Research Institute and Surgery, National University Hospital, Singapore, Singapore (D.P.V.d.K.).

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http://dx.doi.org/10.1161/ATVBAHA.113.303050DOI Listing
March 2014

FLow-induced PRotrusions (FLIPRs): a platelet-derived platform for the retrieval of microparticles by monocytes and neutrophils.

Circ Res 2014 Feb 9;114(5):780-91. Epub 2014 Jan 9.

From the Laboratory of Clinical Chemistry and Haematology (C.T., H.F.H., R.T.U., C.M., P.G.d.G., M.R.), Laboratory of Experimental Cardiology (C.T., G.P., I.E.H.), and Cell Microscopy Center, Department of Cell Biology (H.F.H.), UMC Utrecht, Utrecht, The Netherlands; UMR-S949 INSERM, EFS-Alsace, Université de Strasbourg, Strasbourg, France (A.E., C.G.); Department of Clinical Chemistry, AMC Amsterdam, Amsterdam, The Netherlands (R.N.); and Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom (R.W.F.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.114.30236
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.114.302361DOI Listing
February 2014

Toll-like receptor 4 inhibitor TAK-242 treatment does not influence perfusion recovery in tissue ischemia.

J Cardiovasc Pharmacol 2014 Jan;63(1):16-22

*Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands; †Department of Surgery; and ‡Einthoven Laboratory of Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands; and §Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands.

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http://dx.doi.org/10.1097/FJC.0000000000000019DOI Listing
January 2014

Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events.

Eur Heart J 2013 Dec 11;34(48):3699-706. Epub 2013 Jun 11.

Experimental Cardiology Laboratory (room G02.523), University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands.

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http://dx.doi.org/10.1093/eurheartj/eht186DOI Listing
December 2013

Proteomics of plaques and novel sources of potential biomarkers for atherosclerosis.

Proteomics Clin Appl 2013 Aug 9;7(7-8):490-503. Epub 2013 Jul 9.

Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/prca.201200119DOI Listing
August 2013

Biomechanical factors as triggers of vascular growth.

Cardiovasc Res 2013 Jul 10;99(2):276-83. Epub 2013 Apr 10.

Laboratory of Experimental Cardiology, University Medical Center, G02.523, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvt089DOI Listing
July 2013

Temporal changes of soluble ST2 after cardiovascular interventions.

Eur J Clin Invest 2013 Feb 6;43(2):113-20. Epub 2012 Dec 6.

Department of Experimental Cardiology, University Medical Centre Utrecht, 3584 CX, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/eci.12022DOI Listing
February 2013

Distinct CD44 splice variants differentially affect collateral artery growth.

Curr Vasc Pharmacol 2013 Jan;11(1):13-20

Laboratory of Experimental Cardiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

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January 2013

CD26 inhibition enhances perfusion recovery in ApoE-/-mice.

Curr Vasc Pharmacol 2013 Jan;11(1):21-8

Laboratory of Experimental Cardiology, University Medical Center Utrecht, G02.523, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

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January 2013

Deep proteome profiling of circulating granulocytes reveals bactericidal/permeability-increasing protein as a biomarker for severe atherosclerotic coronary stenosis.

J Proteome Res 2012 Nov 11;11(11):5235-44. Epub 2012 Oct 11.

Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University and Netherlands Proteomics Centre, Utrecht, The Netherlands.

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http://pubs.acs.org/doi/10.1021/pr3004375
Publisher Site
http://dx.doi.org/10.1021/pr3004375DOI Listing
November 2012