Publications by authors named "Ilsa Coleman"

99Publications

Imaging Fibroblast Activation Protein Alpha Improves Diagnosis of Metastatic Prostate Cancer with Positron Emission Tomography.

Clin Cancer Res 2020 Sep 7;26(18):4882-4891. Epub 2020 Jul 7.

Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota.

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http://dx.doi.org/10.1158/1078-0432.CCR-20-1358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683011PMC
September 2020

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress.

Cell Rep 2020 05;31(8):107669

Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Medicine, University of Washington, Seattle, WA 98195, USA; Department of Urology, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453577PMC
May 2020

Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4.

Neoplasia 2020 06 11;22(6):253-262. Epub 2020 May 11.

Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA; Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2020.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218227PMC
June 2020

Comparison of four next generation sequencing platforms for fusion detection: Oncomine by ThermoFisher, AmpliSeq by illumina, FusionPlex by ArcherDX, and QIAseq by QIAGEN.

Cancer Genet 2020 05 7;243:11-18. Epub 2020 Mar 7.

Cytogenetics Laboratory, Seattle Cancer Care Alliance, United States; Clinical Research Division, Fred Hutchinson Cancer Research Center (FHCRC), 825 Eastlake Ave. E., MS: BL103, Seattle, WA 98109, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2020.02.007DOI Listing
May 2020

Exploitation of CD133 for the Targeted Imaging of Lethal Prostate Cancer.

Clin Cancer Res 2020 03 15;26(5):1054-1064. Epub 2019 Nov 15.

Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056526PMC
March 2020

PEG10 Promoter-Driven Expression of Reporter Genes Enables Molecular Imaging of Lethal Prostate Cancer.

Cancer Res 2019 11 17;79(21):5668-5680. Epub 2019 Sep 17.

Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-2181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825593PMC
November 2019

The Aged Microenvironment Influences the Tumorigenic Potential of Malignant Prostate Epithelial Cells.

Mol Cancer Res 2019 01 17;17(1):321-331. Epub 2018 Sep 17.

Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-18-0522DOI Listing
January 2019

A Novel Flavonoid Composition Targets Androgen Receptor Signaling and Inhibits Prostate Cancer Growth in Preclinical Models.

Neoplasia 2018 08 4;20(8):789-799. Epub 2018 Jul 4.

Molecular Oncology and Biomarkers Program, Georgia Cancer Center; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, USA; Department of Urology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA; MetCure Therapeutics LLC, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2018.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034581PMC
August 2018

Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling.

Cancer Cell 2017 10;32(4):474-489.e6

Department of Medicine, University of Washington, Seattle, WA, USA; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Mailstop D4-100, 1100 Fairview Avenue N, Seattle, WA 98109-1024, USA; Department of Urology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA; Department of Pathology, University of Washington, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750052PMC
October 2017

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.

Cell Rep 2017 06;19(10):2045-2059

Centre for Molecular Medicine Norway, Nordic European Molecular Biology Laboratory Partnership, Forskningsparken, University of Oslo, 21 0349 Oslo, Norway; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, 0424 Oslo, Norway; PCUK Movember Centre of Excellence, CCRCB, Queen's University, Belfast BT7 1NN, Northern Ireland, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.05.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675034PMC
June 2017

DNA Damage Induces a Secretory Program in the Quiescent TME that Fosters Adverse Cancer Phenotypes.

Mol Cancer Res 2017 07 29;15(7):842-851. Epub 2017 Mar 29.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859576PMC
July 2017

Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors.

Oncotarget 2017 Jan;8(4):6179-6192

Department of Pathology and Immunology, Baylor College of Medicine and Michael E. DeBakey Department of Veterans Affairs Medical Center Baylor College of Medicine, Houston, 77030, TX, USA.

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http://dx.doi.org/10.18632/oncotarget.14049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351622PMC
January 2017

Expression of STAT3 in Prostate Cancer Metastases.

Eur Urol 2017 03 22;71(3):313-316. Epub 2016 Jun 22.

Department of Translational Medicine, Division of Urological Cancers, Lund University, Malmö, Sweden; Department of Urology, Skåne University Hospital, Lund University, Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2016.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624794PMC
March 2017

Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.

Mol Cancer Res 2016 Apr 11;14(4):374-84. Epub 2016 Jan 11.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Pathology, University of Washington, Seattle, Washington. Department of Urology, University of Washington, Seattle, Washington. Department of Medicine, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582956PMC
April 2016

ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.

Cancer Cell 2015 Jun;27(6):797-808

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Pathology, University of Washington, Seattle, WA 98195, USA; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461839PMC
June 2015

Chemotherapy-induced monoamine oxidase expression in prostate carcinoma functions as a cytoprotective resistance enzyme and associates with clinical outcomes.

PLoS One 2014 8;9(9):e104271. Epub 2014 Sep 8.

Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Department of Pathology, University of Washington, Seattle, Washington, United States of America; Department of Urology, University of Washington, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104271PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157741PMC
November 2015

The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.

Cancer Discov 2014 Nov 13;4(11):1310-25. Epub 2014 Aug 13.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Pathology, University of Washington, Seattle, Washington. Department of Urology, University of Washington, Seattle, Washington. Department of Medicine, University of Washington, Seattle, Washington.

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http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
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http://dx.doi.org/10.1158/2159-8290.CD-13-1010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409786PMC
November 2014

Spheroid culture of LuCaP 147 as an authentic preclinical model of prostate cancer subtype with SPOP mutation and hypermutator phenotype.

Cancer Lett 2014 Sep 3;351(2):272-80. Epub 2014 Jul 3.

Department of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112013PMC
September 2014

Prostate cancer derived prostatic acid phosphatase promotes an osteoblastic response in the bone microenvironment.

Clin Exp Metastasis 2014 Feb 17;31(2):247-56. Epub 2013 Nov 17.

Genitourinary Cancer Research Laboratory, Department of Urology, University of Washington, Box 356510, Seattle, WA, 98195, USA.

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http://link.springer.com/10.1007/s10585-013-9625-2
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http://dx.doi.org/10.1007/s10585-013-9625-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946934PMC
February 2014

Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation.

PLoS One 2013 21;8(5):e63563. Epub 2013 May 21.

Division of Hematology/Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063563PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660401PMC
December 2013

The effects of aging on the molecular and cellular composition of the prostate microenvironment.

PLoS One 2010 Sep 1;5(9). Epub 2010 Sep 1.

Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012501PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931699PMC
September 2010

Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: implications for prostate cancer chemoprevention.

Cancer Res 2010 Feb 2;70(4):1286-95. Epub 2010 Feb 2.

Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, D4-100, Seattle, WA 91809, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822890PMC
February 2010

Transforming Growth Factor-{beta}-Stimulated Clone-22 Is an Androgen-Regulated Gene That Enhances Apoptosis in Prostate Cancer following Insulin-Like Growth Factor-I Receptor Inhibition.

Clin Cancer Res 2009 Dec;15(24):7634-7641

Authors' Affiliations: Departments of Medicine and Urology, University of Washington; Puget Sound Veterans Affairs Health Care System; Fred Hutchinson Cancer Research Center, Seattle, Washington and Imclone Systems, Inc., New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795132PMC
December 2009

Conserved gene expression programs integrate mammalian prostate development and tumorigenesis.

Cancer Res 2009 Mar 17;69(5):1739-47. Epub 2009 Feb 17.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-6817DOI Listing
March 2009

A causal role for ERG in neoplastic transformation of prostate epithelium.

Proc Natl Acad Sci U S A 2008 Feb 1;105(6):2105-10. Epub 2008 Feb 1.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1073/pnas.0711711105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538886PMC
February 2008

Tissue-specific consequences of cyclin D1 overexpression in prostate cancer progression.

Cancer Res 2007 Sep;67(17):8188-97

Department of Cancer Biology, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232-2765, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-0418DOI Listing
September 2007

Genetic background influences murine prostate gene expression: implications for cancer phenotypes.

Genome Biol 2007 ;8(6):R117

Division of Human Biology, Fred Hutchinson Cancer Research Center, Fairview Avenue, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1186/gb-2007-8-6-r117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394769PMC
February 2008

Interaction of IGF signaling and the androgen receptor in prostate cancer progression.

J Cell Biochem 2006 Oct;99(2):392-401

Department of Medicine, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1002/jcb.20929DOI Listing
October 2006

Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo.

Cancer Lett 2006 Dec 23;244(2):274-88. Epub 2006 Feb 23.

Laboratory for Cancer Ontogeny and Therapeutics, Department of Biological Sciences, University of Delaware, Wolf Hall, Newark, DE 19716, USA.

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http://dx.doi.org/10.1016/j.canlet.2005.12.027DOI Listing
December 2006

The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms.

Cancer Res 2006 Jan;66(2):794-802

Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1716DOI Listing
January 2006

Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma.

Clin Cancer Res 2005 May;11(10):3905-14

Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center and Department of Medicine and Oncology, Veterans Affairs Puget Sound Health Care System, University of Washington, Seattle, Washington, USA.

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http://www.pedb.org/PUBLICATIONS/Publications/Bonham_Nelson_
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-04-1974DOI Listing
May 2005

Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma.

Int J Cancer 2005 Apr;114(4):563-71

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1002/ijc.20773DOI Listing
April 2005