Ilkka Julkunen

Ilkka Julkunen

UNVERIFIED PROFILE

Are you Ilkka Julkunen?   Register this Author

Register author
Ilkka Julkunen

Ilkka Julkunen

Publications by authors named "Ilkka Julkunen"

Are you Ilkka Julkunen?   Register this Author

100Publications

1625Reads

41Profile Views

Pandemic influenza A(H1N1pdm09) vaccine induced high levels of influenza-specific IgG and IgM antibodies as analyzed by enzyme immunoassay and dual-mode multiplex microarray immunoassay methods.

Vaccine 2020 Feb 24;38(8):1933-1942. Epub 2020 Jan 24.

Institute of Biomedicine/Virology, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland; Turku University Hospital, Clinical Microbiology, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2020.01.022DOI Listing
February 2020

In vitro production of synthetic viral RNAs and their delivery into mammalian cells and the application of viral RNAs in the study of innate interferon responses.

Methods 2019 Nov 1. Epub 2019 Nov 1.

Institute of Biomedicine, University of Turku and Turku University Hospital, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymeth.2019.10.013DOI Listing
November 2019

Influenza virus infections from 0 to 2 years of age: A birth cohort study.

J Microbiol Immunol Infect 2019 Aug 7;52(4):526-533. Epub 2017 Dec 7.

Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmii.2017.10.007DOI Listing
August 2019

Seasonal influenza vaccines induced high levels of neutralizing cross-reactive antibody responses against different genetic group influenza A(H1N1)pdm09 viruses.

Vaccine 2019 May 4;37(20):2731-2740. Epub 2019 Apr 4.

Expert Microbiology Unit, Department of Health Security, National Institute for Health and Welfare (THL), POB 30, 00271 Helsinki, Finland; Institute of Biomedicine, University of Turku and Turku University Hospital, Kiinamyllynkatu 10, 20520 Turku, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2019.03.078DOI Listing
May 2019

Interleukin-5, interleukin-6, interferon induced protein-10, procalcitonin and C-reactive protein among mechanically ventilated severe community-acquired viral and bacterial pneumonia patients.

Cytokine 2019 01 25;113:272-276. Epub 2018 Jul 25.

Department of Infection Control, Oulu University Hospital, P.O. Box 21, FI-90029 OUH, Finland; Medical Research Center Oulu Research Group of Surgery, Anaesthesiology and Intensive Care, University of Oulu, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cyto.2018.07.019DOI Listing
January 2019

Highly Pathogenic H5N1 Influenza A Virus Spreads Efficiently in Human Primary Monocyte-Derived Macrophages and Dendritic Cells.

Front Immunol 2018 17;9:1664. Epub 2018 Jul 17.

Expert Microbiology Unit, Department of Health Security, National Institute for Health and Welfare, Helsinki, Finland.

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fimmu.2018.01664
Publisher Site
http://dx.doi.org/10.3389/fimmu.2018.01664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056608PMC
July 2018

Narcolepsy Associated with Pandemrix Vaccine.

Curr Neurol Neurosci Rep 2018 06 1;18(7):43. Epub 2018 Jun 1.

Department of Clinical Neurosciences, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11910-018-0851-5
Publisher Site
http://dx.doi.org/10.1007/s11910-018-0851-5DOI Listing
June 2018

Ebolavirus protein VP24 interferes with innate immune responses by inhibiting interferon-λ1 gene expression.

Virology 2017 09 5;509:23-34. Epub 2017 Jun 5.

Institute of Biomedicine/Virology, University of Turku, Kiinamyllynkatu 13, 20520 Turku, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.virol.2017.06.002DOI Listing
September 2017

Production, purification and immunogenicity of recombinant Ebola virus proteins - A comparison of Freund's adjuvant and adjuvant system 03.

J Virol Methods 2017 04 24;242:35-45. Epub 2016 Dec 24.

Department of Virology, University of Turku, Turku, Finland; Viral Infections Unit, National Institute for Health and Welfare, Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jviromet.2016.12.014DOI Listing
April 2017

Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes.

Biochim Biophys Acta 2016 11 21;1859(11):1440-1448. Epub 2016 Sep 21.

Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki 00290, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbagrm.2016.09.005DOI Listing
November 2016

Spectrally and Spatially Multiplexed Serological Array-in-Well Assay Utilizing Two-Color Upconversion Luminescence Imaging.

Anal Chem 2016 Apr 29;88(8):4470-7. Epub 2016 Mar 29.

Department of Biotechnology, University of Turku , Tykistökatu 6 A, FI-20520 Turku, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.6b00337DOI Listing
April 2016

Nuclear Translocation of Crk Adaptor Proteins by the Influenza A Virus NS1 Protein.

Viruses 2016 Apr 15;8(4):101. Epub 2016 Apr 15.

Department of Virology, University of Helsinki and Helsinki University Hospital, 00014 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/v8040101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848595PMC
April 2016

Immuno-modulating properties of saliphenylhalamide, SNS-032, obatoclax, and gemcitabine.

Antiviral Res 2016 Feb 29;126:69-80. Epub 2015 Dec 29.

The Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Finland; Department of Virology, University of Turku, Turku, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.antiviral.2015.12.011DOI Listing
February 2016

RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression.

J Virol 2015 Dec 16;89(23):12014-25. Epub 2015 Sep 16.

Viral Infections Unit, Department of Infectious Diseases, National Institute for Health and Welfare, Helsinki, Finland Department of Virology, University of Turku, Turku, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.01576-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645339PMC
December 2015

[Narcolepsy as an autoimmune disease].

Duodecim 2015 ;131(12):1153-60

View Article

Download full-text PDF

Source
September 2015

Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling.

Nucleic Acids Res 2015 May 29;43(10):5236-48. Epub 2015 Apr 29.

Centre for Structural Biology, Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkv389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446440PMC
May 2015

MAP kinase p38α regulates type III interferon (IFN-λ1) gene expression in human monocyte-derived dendritic cells in response to RNA stimulation.

J Leukoc Biol 2015 Feb 3;97(2):307-20. Epub 2014 Dec 3.

*Virology Unit, Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare, Helsinki, Finland; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, USA; Department of Microbiology, Immunology, and Molecular Genetics, Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, California, USA; Institute of Biotechnology and Department of Biosciences, University of Helsinki, Finland; and Department of Virology, University of Turku, Finland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.2A0114-059RRDOI Listing
February 2015

Blood MxA protein as a marker for respiratory virus infections in young children.

J Clin Virol 2015 Jan 18;62:8-13. Epub 2014 Nov 18.

Department of Virology, University of Turku, Turku, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcv.2014.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106481PMC
January 2015

Efficient replication and strong induction of innate immune responses by H9N2 avian influenza virus in human dendritic cells.

Virology 2014 Dec 25;471-473:38-48. Epub 2014 Oct 25.

Virology Unit, National Institute for Health and Welfare (THL), Mannerheimintie 166, FI-00271 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.virol.2014.10.002DOI Listing
December 2014

Neuroimmunology: Disease mechanisms in narcolepsy remain elusive.

Nat Rev Neurol 2014 Nov 14;10(11):616-7. Epub 2014 Oct 14.

Helsinki Sleep Clinic, VitalMed Research Centre, Sitratori 3, 00420 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nrneurol.2014.191
Publisher Site
http://dx.doi.org/10.1038/nrneurol.2014.191DOI Listing
November 2014

Does autoreactivity have a role in narcolepsy?

Lancet Neurol 2014 Nov;13(11):1072-1073

Institute of Clinical Medicine, University of Helsinki, Helsinki, Finland; Respiratory, Inflammatory and Autoimmune Diseases, Innovative Medicine, AstraZeneca, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1474-4422(14)70168-1DOI Listing
November 2014

Akt inhibitor MK2206 prevents influenza pH1N1 virus infection in vitro.

Antimicrob Agents Chemother 2014 Jul 21;58(7):3689-96. Epub 2014 Apr 21.

Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland Department of Environmental Research, Siauliai University, Siauliai, Lithuania

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02798-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068572PMC
July 2014

Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication.

Virol J 2014 Jul 14;11:128. Epub 2014 Jul 14.

Virology Unit, Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare (THL), Mannerheimintie 166, FIN-00300 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1743-422X-11-128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112715PMC
July 2014

Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination.

Lancet Neurol 2014 Jun;13(6):600-13

Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1474-4422(14)70075-4DOI Listing
June 2014

Human kinome analysis reveals novel kinases contributing to virus infection and retinoic-acid inducible gene I-induced type I and type III IFN gene expression.

Innate Immun 2013 Oct 12;19(5):516-30. Epub 2013 Feb 12.

1Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare (THL), Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1753425912473345DOI Listing
October 2013

Antibody responses against influenza A(H1N1)pdm09 virus after sequential vaccination with pandemic and seasonal influenza vaccines in Finnish healthcare professionals.

Influenza Other Respir Viruses 2013 May 23;7(3):431-8. Epub 2012 Aug 23.

Virology Unit, Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1750-2659.2012.00415.x
Publisher Site
http://dx.doi.org/10.1111/j.1750-2659.2012.00415.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779819PMC
May 2013

Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions.

J Med Virol 2013 Jan 23;85(1):71-82. Epub 2012 Oct 23.

Virology Unit, Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare (THL), Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jmv.23442DOI Listing
January 2013

[Influenza viruses--a challenge for vaccinations].

Duodecim 2012 ;128(18):1919-28

Virologin yksikkö ja kansallinen influenssakeskus, Tartuntatautiseurannan ja -torjunnan osasto, Terveyden ja hyvinvoinnin Iaitos.

View Article

Download full-text PDF

Source
December 2012

Incoming influenza A virus evades early host recognition, while influenza B virus induces interferon expression directly upon entry.

J Virol 2012 Oct 1;86(20):11183-93. Epub 2012 Aug 1.

Department of Infectious Disease Surveillance and Control, Virology Unit, National Institute for Health and Welfare, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.01050-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457146PMC
October 2012

The NS1 protein of influenza A virus blocks RIG-I-mediated activation of the noncanonical NF-κB pathway and p52/RelB-dependent gene expression in lung epithelial cells.

J Virol 2012 Sep 11;86(18):10211-7. Epub 2012 Jul 11.

Institute of Molecular Virology (IMV), Centre for Molecular Biology of Inflammation (ZMBE), Westfälische-Wilhelms-University, Muenster, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.00323-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446553PMC
September 2012

Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin.

Virol J 2012 Aug 21;9:167. Epub 2012 Aug 21.

Virology Unit, Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare (THL), Mannerheimintie 166, FIN-00300 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1743-422X-9-167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493336PMC
August 2012

Minor changes in the hemagglutinin of influenza A(H1N1)2009 virus alter its antigenic properties.

PLoS One 2011 11;6(10):e25848. Epub 2011 Oct 11.

Viral Infections Unit, Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025848PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191144PMC
February 2012

Innate immune responses in human monocyte-derived dendritic cells are highly dependent on the size and the 5' phosphorylation of RNA molecules.

J Immunol 2011 Aug 8;187(4):1713-21. Epub 2011 Jul 8.

National Key Laboratory of Virology and Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan 430072, China.

View Article

Download full-text PDF

Source
http://www.jimmunol.org/content/187/4/1713.full.pdf
Web Search
http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1100361
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1100361DOI Listing
August 2011

Treatment of lymphatic malformations of head and neck with OK-432 sclerotherapy induce systemic inflammatory response.

Eur Arch Otorhinolaryngol 2011 Jan 16;268(1):123-9. Epub 2010 Jul 16.

Department of Otorhinolaryngology, Kuopio University Hospital and University of Kuopio, POB 1777, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00405-010-1332-x
Publisher Site
http://dx.doi.org/10.1007/s00405-010-1332-xDOI Listing
January 2011

TLR ligands induce synergistic interferon-β and interferon-λ1 gene expression in human monocyte-derived dendritic cells.

Mol Immunol 2011 Jan 30;48(4):505-15. Epub 2010 Oct 30.

Department of Vaccination and Immune Protection, National Institute for Heath and Welfare, PO Box 30, FI-00271 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S016158901000585
Publisher Site
http://dx.doi.org/10.1016/j.molimm.2010.10.005DOI Listing
January 2011

Inhibition of dynamin-dependent endocytosis interferes with type III IFN expression in bacteria-infected human monocyte-derived DCs.

J Leukoc Biol 2010 Oct 7;88(4):665-74. Epub 2010 Jul 7.

Department of Vaccination and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.1009651DOI Listing
October 2010

Genetic diversity of the 2009 pandemic influenza A(H1N1) viruses in Finland.

PLoS One 2010 Oct 20;5(10):e13329. Epub 2010 Oct 20.

Viral Infections Unit, Department of Vaccination and Immune Protection, National Institute for Health and Welfare THL, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013329PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958116PMC
October 2010

Pandemic H1N1 2009 influenza A virus induces weak cytokine responses in human macrophages and dendritic cells and is highly sensitive to the antiviral actions of interferons.

J Virol 2010 Feb 25;84(3):1414-22. Epub 2009 Nov 25.

Viral Infections Unit, Department of Vaccination and Immune Protection, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.01619-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812319PMC
February 2010

Cytokine responses in cord blood predict the severity of later respiratory syncytial virus infection.

J Allergy Clin Immunol 2009 Jul 30;124(1):52-58.e1-2. Epub 2009 May 30.

Department of Paediatrics, University of Oulu, PO Box 5000, University of Oulu, Oulu FI-90014, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2009.04.014DOI Listing
July 2009

Hepatitis C virus core, NS3, NS4B and NS5A are the major immunogenic proteins in humoral immunity in chronic HCV infection.

Virol J 2009 Jun 23;6:84. Epub 2009 Jun 23.

Department of Vaccination and Immune Protection, National Institute for Health and Welfare (THL), FI-00271 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1743-422X-6-84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709157PMC
June 2009

Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells.

J Leukoc Biol 2009 Apr;85(4):664-72

Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0808503DOI Listing
April 2009

Critical immunological pathways are downregulated in APECED patient dendritic cells.

J Mol Med (Berl) 2008 Oct 4;86(10):1139-52. Epub 2008 Jul 4.

National Public Health Institute and FIMM, Institute for Molecular Medicine Finland, Biomedicum, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-008-0374-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685494PMC
October 2008

Live Lactobacillus rhamnosus and Streptococcus pyogenes differentially regulate Toll-like receptor (TLR) gene expression in human primary macrophages.

J Leukoc Biol 2008 Oct 14;84(4):1092-100. Epub 2008 Jul 14.

Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.1206737DOI Listing
October 2008

Potentially probiotic bacteria induce efficient maturation but differential cytokine production in human monocyte-derived dendritic cells.

World J Gastroenterol 2008 Sep;14(36):5570-83; discussion 5581-2

Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, Helsinki Finland.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746346PMC
http://dx.doi.org/10.3748/wjg.14.5570DOI Listing
September 2008

NF-kappaB p52, RelB and c-Rel are transported into the nucleus via a subset of importin alpha molecules.

Cell Signal 2008 Aug 1;20(8):1442-51. Epub 2008 Apr 1.

Department of Viral Diseases and Immunology, National Public Health Institute, FIN-00300, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellsig.2008.03.012DOI Listing
August 2008

Effect of probiotic Lactobacillus rhamnosus GG intervention on global serum lipidomic profiles in healthy adults.

World J Gastroenterol 2008 May;14(20):3188-94

University of Helsinki, Institute of Biomedicine, Pharmacology, University of Helsinki, Helsinki 00014, Finland.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712851PMC
http://dx.doi.org/10.3748/wjg.14.3188DOI Listing
May 2008

Activation of pro-matrix metalloproteinase-9 and degradation of gelatin by the surface protease PgtE of Salmonella enterica serovar Typhimurium.

Int J Med Microbiol 2008 Apr 20;298(3-4):263-78. Epub 2007 Sep 20.

General Microbiology, Department of Biological and Environmental Sciences, Faculty of Biosciences, University of Helsinki, PO Box 56, FIN-00014 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijmm.2007.06.004DOI Listing
April 2008

Streptococcus pyogenes activates human plasmacytoid and myeloid dendritic cells.

J Leukoc Biol 2008 Feb 26;83(2):296-304. Epub 2007 Oct 26.

Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FI-00300 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0707457DOI Listing
February 2008

Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling.

J Biol Chem 2008 Feb 28;283(9):5719-27. Epub 2007 Dec 28.

Department of Virology, Haartman Institute, University of Helsinki and Helsinki University Central Hospital, Haartmaninkatu 3 POB 21, FIN-00014, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M707195200
Publisher Site
http://dx.doi.org/10.1074/jbc.M707195200DOI Listing
February 2008

Hepatitis C virus proteins interfere with the activation of chemokine gene promoters and downregulate chemokine gene expression.

J Gen Virol 2008 Feb;89(Pt 2):432-443

Department of Viral Diseases and Immunology, National Public Health Institute, FIN-00300 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/vir.0.83316-0DOI Listing
February 2008

Probiotic Leuconostoc mesenteroides ssp. cremoris and Streptococcus thermophilus induce IL-12 and IFN-gamma production.

World J Gastroenterol 2008 Feb;14(8):1192-203

University of Helsinki, Institute of Biomedicine, Pharmacology, Helsinki 00014, Finland.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690666PMC
http://dx.doi.org/10.3748/wjg.14.1192DOI Listing
February 2008

IFN-alpha regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages.

J Leukoc Biol 2007 Nov 7;82(5):1185-92. Epub 2007 Aug 7.

Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FI-00300, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0307157DOI Listing
November 2007

Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response.

J Mol Med (Berl) 2007 Sep 26;85(9):971-83. Epub 2007 May 26.

Department of Molecular Medicine, National Public Health Institute, Biomedicum, Haartmaninkatu 8, 00290, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-007-0191-4DOI Listing
September 2007

Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells.

J Leukoc Biol 2007 Sep 26;82(3):710-20. Epub 2007 Jun 26.

Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FI-00300 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1189/jlb.0307194
Publisher Site
http://dx.doi.org/10.1189/jlb.0307194DOI Listing
September 2007

Cellular immunity to mumps virus in young adults 21 years after measles-mumps-rubella vaccination.

J Infect Dis 2007 Sep 10;196(6):861-7. Epub 2007 Aug 10.

Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/521029DOI Listing
September 2007

IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes.

J Immunol 2007 Sep;179(6):3434-42

Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.179.6.3434DOI Listing
September 2007

The effect of probiotics on respiratory infections and gastrointestinal symptoms during training in marathon runners.

Int J Sport Nutr Exerc Metab 2007 Aug;17(4):352-63

Institute of Biomedicine, Pharmacology, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1123/ijsnem.17.4.352DOI Listing
August 2007

Type I interferon response against viral and non-viral gene transfer in human tumor and primary cell lines.

J Gene Med 2007 Feb;9(2):122-35

A. I. Virtanen Institute for Molecular Sciences, Department of Biotechnology and Molecular Medicine, University of Kuopio, P.O. Box 1627, FIN-70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jgm.997DOI Listing
February 2007

Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells.

J Immunol 2007 Jan;178(1):253-61

Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.178.1.253DOI Listing
January 2007

Expression of MxA protein in blood lymphocytes of children receiving anticancer chemotherapy.

Pediatr Hematol Oncol 2006 Dec;23(8):649-60

Turku Immunology Centre and Departments of Pediatrics and Virology, University of Turku, Turku, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/08880010600956863DOI Listing
December 2006

The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines.

Microbes Infect 2006 Jul 26;8(8):2138-44. Epub 2006 May 26.

Department of Virology, University of Turku, Kiinamyllynkatu 13, FIN-20520 Turku, Finland.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S128645790600167
Publisher Site
http://dx.doi.org/10.1016/j.micinf.2006.04.005DOI Listing
July 2006

IL-21 enhances SOCS gene expression and inhibits LPS-induced cytokine production in human monocyte-derived dendritic cells.

J Leukoc Biol 2006 Jun 21;79(6):1279-85. Epub 2006 Mar 21.

Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FIN-00300 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0905503DOI Listing
June 2006

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

J Biol Chem 2006 Jan 23;281(4):2095-103. Epub 2005 Nov 23.

Terry Fox Molecular Oncology Group, Lady Davis Institute for Medical Research, and Department of Microbiology, McGill University, Montreal, Quebec H3T 1E2, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M510326200DOI Listing
January 2006