Ilene Galinsky

Ilene Galinsky

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Ilene Galinsky

Ilene Galinsky

Publications by authors named "Ilene Galinsky"

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Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy.

Cell Res 2019 Jun 25;29(6):446-459. Epub 2019 Apr 25.

Cancer Research Institute, Beth Israel Deaconess Cancer Center; Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Ludwig Center at Harvard, Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/articles/s41422-019-0162-7
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http://dx.doi.org/10.1038/s41422-019-0162-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796925PMC
June 2019

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity.

Cell 2019 03 28;176(6):1265-1281.e24. Epub 2019 Feb 28.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Ludwig Center at Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674193009
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http://dx.doi.org/10.1016/j.cell.2019.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515904PMC
March 2019

Neuropathology of a Case With Fatal CAR T-Cell-Associated Cerebral Edema.

J Neuropathol Exp Neurol 2018 10;77(10):877-882

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/jnen/nly064DOI Listing
October 2018

Role of the Advanced Practice Provider in Clinical Trials: Contributions to the Management of Patients Receiving Inotuzumab Ozogamicin.

J Adv Pract Oncol 2017 Sep-Oct;8(6):631-636. Epub 2017 Sep 1.

Dana Farber Cancer Institute, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167080PMC
September 2017

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 07 11;30(1):183. Epub 2016 Jul 11.

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http://dx.doi.org/10.1016/j.ccell.2016.06.008DOI Listing
July 2016

Targeting MTHFD2 in acute myeloid leukemia.

J Exp Med 2016 06 20;213(7):1285-306. Epub 2016 Jun 20.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215 Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142

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http://dx.doi.org/10.1084/jem.20151574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925018PMC
June 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 04;29(4):574-586

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177991PMC
April 2016

Non-hematologic predictors of mortality improve the prognostic value of the international prognostic scoring system for MDS in older adults.

J Geriatr Oncol 2015 Jul 11;6(4):288-98. Epub 2015 Jun 11.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States; Geriatric Research Education and Clinical Center, VA Boston Medical Center, Boston, MA, United States; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jgo.2015.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860010PMC
July 2015

A genome-wide aberrant RNA splicing in patients with acute myeloid leukemia identifies novel potential disease markers and therapeutic targets.

Clin Cancer Res 2014 Mar 27;20(5):1135-45. Epub 2013 Nov 27.

Authors' Affiliations: Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts; Bioinformatics and Computational Genomics Laboratory, Institut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada; Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; Dana-Farber Cancer Institute, Center for Cancer Systems Biology and Department of Genetics, Harvard Medical School, Boston University School of Medicine and Biomedical Engineering Department, Boston University, Boston, Massachusetts; Unité de Génomique du Myélome, Laboratoire UGM, University Hospital, CHU Rangueil, Toulouse, France; Hematology Laboratory, University Hospital; and INSERM U892, Nantes, France; Molecular Diagnostics Laboratory, Dana Farber Cancer Institute, Boston, Massachusetts; Biotique Systems Inc., www.biotiquesystems.com; Adult Leukemia Program, Dana Farber Cancer Institute, Boston, Massachusetts; Brigham and Women's Hospital, Boston, Massachusetts; Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458245PMC
March 2014

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.

Cancer Discov 2014 Mar 17;4(3):362-75. Epub 2013 Dec 17.

Departments of 1Leukemia, 2Pediatrics, and 3Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; 4Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; 5Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; 6The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio; 7AbbVie Inc., North Chicago, Illinois; and 8Department of Laboratory Medicine, University of California San Francisco, San Francisco, California; 9Department of Internal Medicine III, University Hospital of Ulm, Ulm; 10MLL Munich Leukemia Laboratory, Munich, Germany.

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http://research4.dfci.harvard.edu/letai/Publications/2013-12
Web Search
http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
Publisher Site
http://dx.doi.org/10.1158/2159-8290.CD-13-0609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975047PMC
March 2014

SYK is a critical regulator of FLT3 in acute myeloid leukemia.

Cancer Cell 2014 Feb;25(2):226-42

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, Boston, MA 02215, USA; The Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106711PMC
February 2014

The nurse liaison role in the cooperative group setting.

Semin Oncol Nurs 2014 Feb 18;30(1):11-6. Epub 2013 Dec 18.

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http://dx.doi.org/10.1016/j.soncn.2013.12.003DOI Listing
February 2014

Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells.

Mol Cancer Ther 2013 Dec 15;12(12):2651-62. Epub 2013 Oct 15.

Corresponding Authors: Kalindi Parmar, Division of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0103-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089878PMC
December 2013

Guide to interpreting disease responses in chronic myeloid leukemia.

J Adv Pract Oncol 2012 Jul;3(4):225-36

Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093342PMC
http://dx.doi.org/10.6004/jadpro.2012.3.4.3DOI Listing
July 2012

Discovery and characterization of novel mutant FLT3 kinase inhibitors.

Mol Cancer Ther 2010 Sep 31;9(9):2468-77. Epub 2010 Aug 31.

Department of Medical Oncology/Hematologic Neoplasia, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-0232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967795PMC
September 2010

CNS relapse in acute promyeloctyic leukemia.

J Clin Oncol 2010 Aug 7;28(24):e409-11. Epub 2010 Jun 7.

Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1200/JCO.2009.27.1577DOI Listing
August 2010

Identification of AML1-ETO modulators by chemical genomics.

Blood 2009 Jun 17;113(24):6193-205. Epub 2009 Apr 17.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Children's Hospital Boston, Harvard Medical School, MA 02115, USA.

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http://dx.doi.org/10.1182/blood-2008-07-166090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699238PMC
June 2009

Practical management of dasatinib for maximum patient benefit.

Clin J Oncol Nurs 2009 Jun;13(3):329-35

Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1188/09.CJON.329-335DOI Listing
June 2009

Low dose interleukin-2 following intensification therapy with high dose cytarabine for acute myelogenous leukemia in first complete remission.

Am J Hematol 2008 Oct;83(10):771-7

Department of Medical Oncology, Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://doi.wiley.com/10.1002/ajh.21253
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http://dx.doi.org/10.1002/ajh.21253DOI Listing
October 2008

Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells.

Mol Cancer Ther 2008 May 29;7(5):1121-9. Epub 2008 Apr 29.

Department of Medical Oncology/Hematologic Neoplasia, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034541PMC
May 2008

Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation.

Nat Med 2007 Jan 10;13(1):78-83. Epub 2006 Dec 10.

Laboratory of Development and Diseases, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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http://dx.doi.org/10.1038/nm1512DOI Listing
January 2007

Quantitative monitoring of BCR/ABL transcript during STI-571 therapy.

Leuk Lymphoma 2002 Dec;43(12):2281-9

Center for Hematologic Oncology, Department of Biostatistics, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1080/1042819021000039992DOI Listing
December 2002